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Prothiaden 50 mg Tablet

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Composition for Prothiaden 50 mg Tablet

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Primary uses of Prothiaden 50 mg Tablet

Depression, Neuropathic pain, Anxiety disorder
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Medicine Overview of Prothiaden Tablet

uses

Uses of Prothiaden Tablet

Prothiaden 50 mg Tablet is used in the treatment of depression, neuropathic pain and anxiety disorder. It is used in patients intolerant of or unresponsive to alternative treatment options for depression.
uses

Prothiaden Tablet side effects

Common

Side Effects of Prothiaden are Dryness in mouth, Blurred vision, Sleepiness, Increased heart rate, Orthostatic hypotension (sudden lowering of blood pressure on standing), Weight gain, Difficulty in urination, Constipation.

uses

How to use Prothiaden Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Prothiaden 50 mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Prothiaden Tablet works

Prothiaden 50 mg Tablet increases the levels of chemical messengers in the brain that help in regulating the mood and treat depression.

In Depth Information on Prothiaden Tablet

Expert advice for Prothiaden Tablet

  • The main dose should be taken at night as this drug may produce drowsiness or sleepiness.
  • It can take 4 to 6 weeks for Prothiaden 50 mg Tablet to start working.
  • You should continue the treatment for at least 6 months after you feel better to stop depression from coming back.
  • If your doctor asks you to stop Prothiaden 50 mg Tablet, you should reduce the dose slowly over 4 weeks. You should not discontinue it abruptly.
  • Avoid driving or operating machinery as it may decrease alertness.
  • Avoid consuming alcohol when taking the Prothiaden 50 mg Tablet, as it may cause excessive drowsiness and calmness.
  • The addiction/dependence potential of Prothiaden 50 mg Tablet is very less.
  • It may be extremely dangerous in overdose.
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Prothiaden Tablet related warnings
Special precautions for Prothiaden Tablet
Alcohol
Interaction with alcohol is unknown. Please consult your doctor.
Pregnancy
WEIGH RISKS VS BENEFITS
Prothiaden 50 mg Tablet may be unsafe to use during pregnancy.
Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
Lactation
CAUTION
Prothiaden 50 mg Tablet is probably unsafe to use during lactation. Limited human data suggest that the drug could represent a significant risk to the baby.
Driving
It is not known whether Prothiaden 50 mg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney
There is limited information available on the use of Prothiaden 50 mg Tablet in patients with kidney disease. Please consult your doctor.
However, some studies suggest a cautious use of this medicine in patients with kidney disease.
Liver
There is limited information available on the use of Prothiaden 50 mg Tablet in patients with liver disease. Please consult your doctor.

What if you miss a dose of Prothiaden Tablet?uses

If you miss a dose of Prothiaden 50 mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Patient Concerns

User Submitted Feedback For Prothiaden 50 mg Tablet

Frequently asked questions about Prothiaden Tablet

Frequently asked questions about Dosulepin / Dothiepin

No. Prothiaden is an antidepressant (TCA) that is used to treat depression, nerve pain, and anxiety disorder. It can cause drowsiness or sedation as a side effect. Therefore caution is advised when driving or operating dangerous machinery and even when getting out of bed at night.
No. Prothiaden is not a muscle relaxant. It is a tricyclic antidepressant (TCA) used in the treatment of depression, nerve pain, and anxiety disorder.
Q. What is the difference between Prothiaden and amitriptyline?
Prothiaden is chemically related to Amitriptyline and both are tricyclic antidepressant (TCA) medicine. There is overlap in pharmacological property of this medicine.
Q. Is Prothiaden the same as doxepin?
Prothiaden and doxepin are different medicines but belong to the similar chemical class. Doxepin, at low doses, can improve sleep in patients with insomnia. It is also available in the topical form for use in various neuro-dermatitis syndrome, especially itching.
If your doctor asks you to stop Prothiaden, you should reduce the dose slowly over 4 weeks. You should not discontinue it abruptly. Sudden discontinuation may cause aggression, anxiety, blurred vision, concentration impairment, constipation and crying spell.
Yes. Prothiaden can be fatal (can cause death) in overdose. This is due to a life-threatening or dangerous side effect in overdose like hyperthermia, seizure, arrhythmia, tachycardia, orthostatic hypotension or sudden death. That's why it is generally not considered a first-line option for depression because of side effect profile.
Q. Can Prothiaden be used along with mirtazapine?
It is better to avoid Prothiaden with mirtazapine. Mirtazapine, which is used in the treatment of depression, can potentiate the sedative effects of Prothiaden.
Q. Can Prothiaden be used with citalopram?
No. Citalopram and Prothiaden both are the antidepressant. Citalopram may increase the high blood level of Prothiaden. This may lead to a life-threatening or dangerous side effect of hyperthermia, seizure, arrhythmia, tachycardia, orthostatic hypotension or sudden death.
Q. Can Prothiaden be used with sertraline?
No. Sertraline and Prothiaden both are the anti-depressant. Sertraline may increase the high blood level of Prothiaden. This may lead to a life-threatening or dangerous side effect of hyperthermia, seizure, arrhythmia, tachycardia, orthostatic hypotension or sudden death.
Q. Can I take Prothiaden with diazepam?
It is better to avoid this combination. Diazepam is a sedative drug and Prothiaden may cause sedation as a side effect too. Taking both of them together can increase the drowsiness or sleepiness. Inform your doctor if you are taking diazepam.
No. Prothiaden is not approved for the treatment of trigeminal neuralgia. Trigeminal neuralgia is a chronic pain condition that affects the trigeminal or 5th cranial nerve, one of the most widely distributed nerves in the head.
No. Prothiaden is not approved for the treatment of burning mouth syndrome. Burning mouth syndrome is a painful condition of mouth that is burning, scalding, tingling or feeling of numbness that may occur every day for months or longer.
Yes. Prothiaden is indicated for the treatment of depression. It has a potential advantage in the patient with depression if associated with insomnia and anxiety. It is generally not considered a first-line option for depression because of side effect profile but very useful for severe or treatment-resistant depression.
No. Prothiaden is not approved for the treatment of Irritable Bowel Syndrome (IBS). Irritable Bowel Syndrome is a functional gastrointestinal disorder characterised by chronic or recurrent abdominal pain or discomfort associated with altered bowel habits.
Yes. Prothiaden may be used for the treatment of insomnia (too much arousal both at night and during the day) associated with depression. Because it can cause drowsiness or sedation as side effects, it is effective in treating insomnia associated with depression.
Yes. Prothiaden is not approved for the treatment of fibromyalgia. Fibromyalgia is a pain syndrome with tenderness but no structural pathology in muscles, ligamanets or joints.
Yes. Prothiaden is indicated for the treatment of nerve pain/neuropathic pain. Chronic pain/Neuropathic pain is described as pain that arises from damage to, or dysfunction of, any part of peripheral or central nervous system. It is associated with the disease which can affect nerves like diabetes mellitus or herpes infections.

Severely interacts with other drugs like

Taking Prothiaden with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Prothiaden with Moxonidine
LIFE-THREATENING
Medicines with composition Moxonidine: Moxilong, Moxcent, Moxovas, Moxopress
Prothiaden with Moclobemide
LIFE-THREATENING
Medicines with composition Moclobemide: Trima, Rimarex
Prothiaden with Lorazepam
SERIOUS
Prothiaden with Midazolam
SERIOUS
Medicines with composition Midazolam: Medzol, Mezolam, Midfast, Fulsed, Midosed, Midzee, Benzosed, Megarest
Prothiaden with Terbinafine
SERIOUS
Medicines with composition Terbinafine: Terbicutis, Tzorg, Tinazen, Terfast, Fluty TF, Terbit, Tinafine
Prothiaden with Primidone
SERIOUS
Medicines with composition Primidone: Mysoline
Prothiaden with Cinacalcet
SERIOUS
Medicines with composition Cinacalcet: Capicet, Setz
Prothiaden with Paroxetine
SERIOUS
Medicines with composition Paroxetine: Parox, Pirotin, Paropex, Depaxil, Patriot, Xet, Parocen, Paroxee, Pxt, Praxet, Parot, Paxidep, Pxn, Emoxet, Paxiford, XL Paro
Prothiaden with Clonidine
SERIOUS
Medicines with composition Clonidine: Arkamin, Cloneon, Catapres
Prothiaden with Phenobarbitone
SERIOUS
Medicines with composition Phenobarbitone: Nytoin, Barbee, Gardenal, Fenobarb, Luminal, Beetal, Emgard
Prothiaden with Nalbuphine
SERIOUS
Medicines with composition Nalbuphine: Rubuphine, Nalfy, Nacphin
Prothiaden with Codeine
SERIOUS
Medicines with composition Codeine: Montokuf
Prothiaden with Etizolam
SERIOUS
Medicines with composition Etizolam: Etezole, Etilax, Etirest, Etimark, Etizep, Etilaam, Solopose, Lam ET, Suprabenz, Sylkam, Etizoram, New Zomnia
Prothiaden with Pentazocine
SERIOUS
Medicines with composition Pentazocine: Fortwin
Prothiaden with Butorphanol
SERIOUS
Medicines with composition Butorphanol: Butodol
Prothiaden with Rasagiline
SERIOUS
Medicines with composition Rasagiline: Rasalect, Relgin
Prothiaden with Ethylmorphine
SERIOUS
Medicines with composition Ethylmorphine: Dionindon
Prothiaden with Chlordiazepoxide
SERIOUS
Medicines with composition Chlordiazepoxide: Zepox, Anxibrium, Poxid, Peaceoxide, Anxon H, Equilibrium, Cloxide, Librel, Anxizide
Prothiaden with Ritonavir
SERIOUS
Medicines with composition Ritonavir: Viriton, Ritomune, Ritomax
Prothiaden with Lithium
SERIOUS
Medicines with composition Lithium: Lithocent, Lisalt, Lithocap, Carbolith, Hethium, Zecarb, Lalithium, T Lith, Tricab
Prothiaden with Clobazam
SERIOUS
Prothiaden with Fluoxetine
SERIOUS
Prothiaden with Fluvoxamine
SERIOUS
Medicines with composition Fluvoxamine: Voxinix, Uvox, Voxidep, Voxazen, Voxamin, Psyvoxin, Fluxam, Sorest, Fluvoxin, Fluvo
Prothiaden with Nitrazepam
SERIOUS
Medicines with composition Nitrazepam: Nap, Nitraz, Nzm, Sopor, N Tra, Nira, Hypnoril, Nitab, Hypnocent, Nite, Nitrosun, Nitavan
Prothiaden with Flurazepam
SERIOUS
Medicines with composition Flurazepam: Nindral
Prothiaden with Venlafaxine
SERIOUS
Medicines with composition Venlafaxine: Venlift, Ventee, Venpad, Venlor, Venla, Flavix, Venjoy, Nutraport, Venlaway, Sentosa, Ventin, Veniz
Prothiaden with Citalopram
SERIOUS
Medicines with composition Citalopram: Vocita, Olarc, Citopam, Cetadep, Topdep, Celica, Citalomine, Citalent, Citola, Cytop, Madam
Prothiaden with Diazepam
SERIOUS
Medicines with composition Diazepam: Peptica, Placidox, Shipam, Anxol, D P M, Paxum, Dizep, Juniz Rds, Starlium, Repam
Prothiaden with Dapoxetine
SERIOUS
Medicines with composition Dapoxetine: Actinex, DA Sutra, Stay Tal, Dapoxy, Dapnex, Duraject, Appynite, Ristor, Dejac
Prothiaden with Indinavir
SERIOUS
Medicines with composition Indinavir: Indivan

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