Prothiaden 50 mg Tablet

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Overview

Uses of Prothiaden Tablet
Prothiaden 50 mg Tablet is used in the treatment of depression, neuropathic pain and anxiety disorder. It is used in patients intolerant of or unresponsive to alternative treatment options for depression.
Prothiaden Tablet side effects
Common
  • Dryness in mouth
  • Blurred vision
  • Sleepiness
  • Increased heart rate
  • Orthostatic hypotension (sudden lowering of blood pressure on standing)
  • Weight gain
  • Difficulty in urination
  • Constipation
How to use Prothiaden Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Prothiaden 50 mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
How Prothiaden Tablet works
Prothiaden 50 mg Tablet increases the levels of chemical messengers in the brain that help in regulating the mood and treat depression.
Prothiaden Tablet related warnings
Alcohol
Interaction with alcohol is unknown. Please consult your doctor.
Pregnancy
WEIGH RISKS VS BENEFITS
Prothiaden 50 mg Tablet may be unsafe to use during pregnancy.
Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
Lactation
CAUTION
Prothiaden 50 mg Tablet is probably unsafe to use during lactation. Limited human data suggest that the drug could represent a significant risk to the baby.
Driving
It is not known whether Prothiaden 50 mg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney
There is limited information available on the use of Prothiaden 50 mg Tablet in patients with kidney disease. Please consult your doctor.
However, some studies suggest a cautious use of this medicine in patients with kidney disease.
Liver
There is limited information available on the use of Prothiaden 50 mg Tablet in patients with liver disease. Please consult your doctor.
What if you miss a dose of Prothiaden Tablet?
If you miss a dose of Prothiaden 50 mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Prothiaden 50 mg Tablet
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Expert Advice

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  • The main dose should be taken at night as this drug may produce drowsiness or sleepiness.
  • It can take 4 to 6 weeks for Prothiaden 50 mg Tablet to start working.
  • You should continue the treatment for at least 6 months after you feel better to stop depression from coming back.
  • If your doctor asks you to stop Prothiaden 50 mg Tablet, you should reduce the dose slowly over 4 weeks. You should not discontinue it abruptly.
  • Avoid driving or operating machinery as it may decrease alertness.
  • Avoid consuming alcohol when taking the Prothiaden 50 mg Tablet, as it may cause excessive drowsiness and calmness.
  • The addiction/dependence potential of Prothiaden 50 mg Tablet is very less.
  • It may be extremely dangerous in overdose.

Interaction with Drugs

Taking Prothiaden with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Zosert
SERIOUS
Brand(s): Risure
SERIOUS
Brand(s): Eurolam
SERIOUS
Brand(s): Tremash
SERIOUS
Brand(s): Panik
SERIOUS
Brand(s): Psycopan
SERIOUS
Brand(s): Shinosun
SERIOUS
Brand(s): Psycolith
SERIOUS
Brand(s): Leparox, Prx
SERIOUS
Brand(s): Vlx
SERIOUS

Patient Concerns

Questions Related to Prothiaden

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I feel like earthquake is coming & I will fainting. I think I have stress disorder. please tell me what will I do. I take pxr12. 5 in the morning & prothiaden 50mg in night at bed timedoctor please help me
Dr. Jyoti Kapoor Madan
Psychiatrist
Based on your clinical history, your doctor plans the type of medicine and it's dose and duration. For first episode of anxiety/ depression/ panic, the usual maintenance phase is 6 months of asymptomatic period, after which medicines can be gradually tapered. But treatment may need to continue longer depending on severity and frequency of episodes. Treatment for Recurrent Depressive Disorder , psychotic disorders, Bipolar Affective Disorder and OCD usually lasts for much longer.To monitor any potential side effects and to take any decision to change medication or stop them, several factors have to be taken in account for which regular follow up with your psychiatrist is important. For second opinion, seek a proper consultation with another psychiatrist and take along your previous prescriptions.
Sir, I have been prescribed prothiaden for depression before 1 year and i'm recovered Now I'm taking inosert-sterline for anxiety both these medicines are prescribed by a psychiatrist kindly help me to know difference between the medicines
Dr. Jyoti Kapoor Madan
Psychiatrist
Prothiaden belongs to TCA class od antidepressants and Sertraline belongs to SSRI group of antidepressants. The side effect profile of SSRIs is better and therefore these drugs are more ofte prescribed and can be continued for prolonged periods.
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FAQs

Q. Is Prothiaden a sedative?
No. Prothiaden is an antidepressant (TCA) that is used to treat depression, nerve pain, and anxiety disorder. It can cause drowsiness or sedation as a side effect. Therefore caution is advised when driving or operating dangerous machinery and even when getting out of bed at night.
Q. Is Prothiaden a muscle relaxant?
No. Prothiaden is not a muscle relaxant. It is a tricyclic antidepressant (TCA) used in the treatment of depression, nerve pain, and anxiety disorder.
Q. What is the difference between Prothiaden and amitriptyline?
Prothiaden is chemically related to Amitriptyline and both are tricyclic antidepressant (TCA) medicine. There is overlap in pharmacological property of this medicine.
Q. Is Prothiaden the same as doxepin?
Prothiaden and doxepin are different medicines but belong to the similar chemical class. Doxepin, at low doses, can improve sleep in patients with insomnia. It is also available in the topical form for use in various neuro-dermatitis syndrome, especially itching.
Q. How to stop Prothiaden?
If your doctor asks you to stop Prothiaden, you should reduce the dose slowly over 4 weeks. You should not discontinue it abruptly. Sudden discontinuation may cause aggression, anxiety, blurred vision, concentration impairment, constipation and crying spell.
Q. Is Prothiaden fatal?
Yes. Prothiaden can be fatal (can cause death) in overdose. This is due to a life-threatening or dangerous side effect in overdose like hyperthermia, seizure, arrhythmia, tachycardia, orthostatic hypotension or sudden death. That's why it is generally not considered a first-line option for depression because of side effect profile.
Q. Can Prothiaden be used along with mirtazapine?
It is better to avoid Prothiaden with mirtazapine. Mirtazapine, which is used in the treatment of depression, can potentiate the sedative effects of Prothiaden.
Q. Can Prothiaden be used with citalopram?
No. Citalopram and Prothiaden both are the antidepressant. Citalopram may increase the high blood level of Prothiaden. This may lead to a life-threatening or dangerous side effect of hyperthermia, seizure, arrhythmia, tachycardia, orthostatic hypotension or sudden death.
Q. Can Prothiaden be used with sertraline?
No. Sertraline and Prothiaden both are the anti-depressant. Sertraline may increase the high blood level of Prothiaden. This may lead to a life-threatening or dangerous side effect of hyperthermia, seizure, arrhythmia, tachycardia, orthostatic hypotension or sudden death.
Q. Can I take Prothiaden with diazepam?
It is better to avoid this combination. Diazepam is a sedative drug and Prothiaden may cause sedation as a side effect too. Taking both of them together can increase the drowsiness or sleepiness. Inform your doctor if you are taking diazepam.
Q. Can Prothiaden be used in the treatment of trigeminal neuralgia?
No. Prothiaden is not approved for the treatment of trigeminal neuralgia. Trigeminal neuralgia is a chronic pain condition that affects the trigeminal or 5th cranial nerve, one of the most widely distributed nerves in the head.
Q. Can Prothiaden be used in the treatment of burning mouth syndrome?
No. Prothiaden is not approved for the treatment of burning mouth syndrome. Burning mouth syndrome is a painful condition of mouth that is burning, scalding, tingling or feeling of numbness that may occur every day for months or longer.
Q. Can I take Prothiaden for depression?
Yes. Prothiaden is indicated for the treatment of depression. It has a potential advantage in the patient with depression if associated with insomnia and anxiety. It is generally not considered a first-line option for depression because of side effect profile but very useful for severe or treatment-resistant depression.
Q. Can Prothiaden used to treat IBS (Irritable Bowel Syndrome)?
No. Prothiaden is not approved for the treatment of Irritable Bowel Syndrome (IBS). Irritable Bowel Syndrome is a functional gastrointestinal disorder characterised by chronic or recurrent abdominal pain or discomfort associated with altered bowel habits.
Q. Can Prothiaden be used to treat insomnia with depression?
Yes. Prothiaden may be used for the treatment of insomnia (too much arousal both at night and during the day) associated with depression. Because it can cause drowsiness or sedation as side effects, it is effective in treating insomnia associated with depression.
Q. Can I use Prothiaden for fibromyalgia?
Yes. Prothiaden is not approved for the treatment of fibromyalgia. Fibromyalgia is a pain syndrome with tenderness but no structural pathology in muscles, ligamanets or joints.
Q. Can I use Prothiaden for nerve pain?
Yes. Prothiaden is indicated for the treatment of nerve pain/neuropathic pain. Chronic pain/Neuropathic pain is described as pain that arises from damage to, or dysfunction of, any part of peripheral or central nervous system. It is associated with the disease which can affect nerves like diabetes mellitus or herpes infections.

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Information last updated by Dr. Varun Gupta, MD Pharmacology on 29th Nov 2017.
Manufacturer/Marketer Address
16th Floor, Godrej BKC, Plot – C, “G” Block, Bandra-Kurla Complex, Bandra (East), Mumbai – 400 051, India
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MRP
197.91
15 tablets in 1 strip
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