Prohale 300 SR Tablet is a natural female sex hormone, progesterone. It is used to treat menstrual and pregnancy-related issues that are caused due to hormonal imbalance.

Prohale 300 SR Tablet is also prescribed along with estrogen as a part of hormonal replacement therapy for preventing endometrial hyperplasia (thickening of the lining of the uterus). It should be taken without food, preferably in the evening or at bedtime. It should be taken at the same time each day to get the most benefit. You should continue taking it for as long as your doctor has told you to, even if you feel well.

The most common side effects include abdominal bloating, abdominal pain, dizziness, headache, depression, breast tenderness, hot flushes, vaginal discharge, joint paint, and urinary incontinence. Side effects are more common during the first few weeks and usually lessen as your body gets used to the medicine. You may also experience bleeding or spotting between your periods, consult with your doctor if it happens frequently. If you experience dizziness or tiredness, avoid driving or activity which requires mental concentration.

Before taking this medicine, inform your doctor if you have, or have had, breast cancer, unusual bleeding in the vagina, or liver disease. You will probably have several tests both before and during treatment to check your womb. Also, tell your doctor what other medicines you are taking as some may affect, or be affected by, this medicine.

Uses of Prohale Tablet SR

Benefits of Prohale Tablet SR

In Hormone replacement therapy

Hormone Placement Therapy (HRT) is a treatment to relieve symptoms of menopause such as hot flushes, night sweats, mood swings, vaginal dryness and reduced sex drive. Since menopause can last for several years, this treatment can make a big improvement to your daily life and mood. You should use this medicine as it is prescribed, and for as long as it is prescribed by your doctor.

In Female infertility

Prohale 300 SR Tablet contains progesterone, a female hormone that is important in the regulation of ovulation and menstruation. It is used to cause menstrual periods in women who have not reached menopause but are not having periods due to a lack of natural progesterone in the body. Progesterone helps to prepare the uterus for pregnancy by causing the uterus lining (endometrium) to thicken. This increases the chance of a successful pregnancy. You should use the medicine as prescribed for it to be effective. You may be asked to continue with this treatment for a period after becoming pregnant.

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Side effects of Prohale Tablet SR

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Prohale

Abdominal bloating
Hot flushes
Vaginal discharge
Urinary incontinence
Headache
Fatigue
Joint pain
Cough
Abnormal menstrual bleeding
Musculoskeletal (bone, muscle or joint) pain
Slurred speech
Pain behind eyes
Vertigo

Severe side effects of Prohale

Nausea
Sleepiness
Abdominal pain
Absence of menstrual periods
Itching
Change in body weight
Breast tenderness
Depression
Abnormal vaginal bleeding
Menstrual disorder
Edema (swelling)
Changes in cervical ectropion
Changes in cervical secretion
Cholestatic jaundice
Nipple discharge
Injection site reactions (pain, swelling, redness)
Red spots or bumps
Acne
Hair loss
Excessive hair growth on face
Anaphylactic reaction
Fever
Insomnia (difficulty in sleeping)

How to use Prohale Tablet SR

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Prohale 300 SR Tablet is to be taken empty stomach.

How Prohale Tablet SR works

Prohale 300 SR Tablet is a progesterone (female hormone). It works on the lining of the uterus and helps to establish and maintain pregnancy in infertile women. It helps in protecting the uterus from the negative effects of oestrogen when used for the treatment of postmenopausal symptoms.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Prohale 300 SR Tablet. Please consult your doctor.

Pregnancy

SAFE IF PRESCRIBED

Prohale 300 SR Tablet is safe to use during pregnancy. Most studies have shown low or no risk to the developing baby.

Breast feeding

SAFE IF PRESCRIBED

Prohale 300 SR Tablet is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.

Driving

UNSAFE

Prohale 300 SR Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CONSULT YOUR DOCTOR

There is limited information available on the use of Prohale 300 SR Tablet in patients with kidney disease. Please consult your doctor.

Liver

CONSULT YOUR DOCTOR

There is limited information available on the use of Prohale 300 SR Tablet in patients with liver disease. Please consult your doctor.
Use of Prohale 300 SR Tablet is however not recommended in patients with severe liver disease.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Prohale 300 SR Tablet

₹51.6/Tablet SR

Michelle -SR Tablet

Akumentis Healthcare Ltd

₹47.7/tablet sr

8% cheaper

Emprogest -SR 300 Tablet

Emcure Pharmaceuticals Ltd

₹43.7/tablet sr

15% cheaper

Nidagen -SR 300 Tablet

Systopic Laboratories Pvt Ltd

₹38.6/tablet sr

25% cheaper

Posito SR 300 Tablet

Eris Lifesciences Ltd

₹49.2/tablet sr

5% cheaper

Pregaloop Tablet SR

Shree Venkatesh International Limited

₹54.2/tablet sr

5% costlier

View all substitutes

Quick tips

Prohale 300 SR Tablet is used in the treatment of female infertility and as a part of hormone replacement therapy.
It regulates menstrual cycles, treats heavy bleeding, and prevents thickening of the uterus.
It is also used to restore menstruation in women with secondary amenorrhea (the absence of menstrual cycles).
It should be taken without food, preferably in the evening or at bedtime.
It may cause sleepiness or drowsiness. Don't drive or do anything that requires mental focus until you know how Prohale 300 SR Tablet affects you.
It may cause bleeding or spotting in between menstrual periods. Let your doctor know if this occurs frequently.

Fact Box

Chemical Class

Progesterone Derivative

Habit Forming

Therapeutic Class

GYNAECOLOGICAL

Action Class

Natural Progesterone

Patient concerns

I have been told by doctors I have cystitis also simple cyst in right ovary . What should I be doing its been two years I have this issue

Dr. Megha Tuli

Obstetrics and Gynaecology

Hi PATIENT hormone therapy helps with cysts. Ask your doctor for a hormone replacement.

I am a male to female transsexual and I need Bilateral Orchiectomy at a fair cost I am already on hormone replacement therapy for 2 years anti androgen/spirnolactone (Aldactone) and estrodiol valerate progynova, I need to have bilateral orchiectomy at the cheapest option

Dr. Deepak Kumar Soni

Ayurveda

Hi Kindly consult to your nearest doctor

I have sexual hormone problem and infertility problem. 30 millions sperm count,motility 50 only.please send me prescription.

Dr. Pranay Gandhi

Sexology

sperm count is normal so is motility. for increasing ur testosterone levels 1.stop smoking and alcohol 2.join a gym and reduce weight. Do weight lifting exercises. 3.tablet sildenafil or viagra 1 tablet 1 hour before sexual activity. 4.Get tested so that u don?t have any of the following causes: 1.heart diseases 2. diabetes 3.neurological problems 4.hormonal problems 5.drug side effects

What are the side effects of prolonged usage of thyronorm medicine as I am having hypothyroidism since the last 20 years and I am taking the medicine since then . Thanks

Dr. Sfurti Mann

Internal Medicine

It is thyroxin hormone given as replacement of the hormone thyroxin which your body is not producing adequately. If it is being taken in the correct dose maintains your TSH in normal range then it has no side effects.

User feedback

Patients taking Prohale 300 SR Tablet

Once A Day

95%

Twice A Day

FAQs

Q. Can you take Prohale 300 SR Tablet every day?

Yes, Prohale 300 SR Tablet can be taken every day. It is usually prescribed to be taken once daily in the evening or at bedtime. The usual duration of prescription may vary from 10-12 days a month to 25 days a month. However, the number of days for which you will need to take this medicine in each cycle will be suggested by your doctor depending upon your health condition.

Q. Does Prohale 300 SR Tablet cause weight gain?

Yes, taking Prohale 300 SR Tablet may cause weight gain. The weight gain may be due to water retention and may not be a serious sign. However, contact your doctor in case your weight gain is worrying you. The risk of weight gain is generally less if Prohale 300 SR Tablet is taken with estrogen as a combined pill. But, do not start any hormonal therapy without consulting your doctor.

Q. How is progesterone beneficial for fertility and pregnancy?

Progesterone is a very crucial hormone in fertility. It is the hormone secreted by the ovaries that helps prepare the uterus for pregnancy and maintain it. Prohale 300 SR Tablet (form of progesterone) is given as a medicine in cases of infertility to support the uterus in preparing itself for the pregnancy and to prevent the abortions in some cases. It is also used to prevent premature labor.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Chrousos GP. The Gonadal Hormones & Inhibitors. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 706-707.
Levin ER, Hammes SR. Estrogens and Progestins. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1180-85.
Mayo Clinic. Progesterone. [Accessed 03 Apr. 2019] (online) Available from:
Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 03 Apr. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 04 Apr. 2019] (online) Available from:

Manufacturer/Marketer address

B - 4/17, CHITRAKOOT (BASEMENT), NEAR CHITRAKOOT STADIUM JAIPUR - 302021, Rajasthan INDIA

Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.