Profine 100 Soft Gelatin Capsule
Prescription Required
Product introduction
Profine 100 Soft Gelatin Capsule is a natural female sex hormone, progesterone. It is used to treat menstrual and pregnancy-related issues that are caused due to hormonal imbalance.
Profine 100 Soft Gelatin Capsule is also prescribed along with estrogen as a part of hormonal replacement therapy for preventing endometrial hyperplasia (thickening of the lining of the uterus). It should be taken with food. It should be taken at the same time each day to get the most benefit. You should continue taking it for as long as your doctor has told you to, even if you feel well.
The most common side effects include headache, breast pain, irregular vaginal bleeding or spotting, stomach or abdominal cramps, bloating, nausea and vomiting, hair loss, edema, and vaginal yeast infection. Side effects are more common during the first few weeks and usually lessen as your body gets used to the medicine. You may also experience bleeding or spotting between your periods, consult with your doctor if it happens frequently.
Before taking this medicine, inform your doctor if you have, or have had, breast cancer, unusual bleeding in the vagina, or liver disease. You will probably have several tests both before and during treatment to check your womb. Also, tell your doctor what other medicines you are taking as some may affect, or be affected by, this medicine. In general, it is advisable to avoid alcohol and smoking.
Profine 100 Soft Gelatin Capsule is also prescribed along with estrogen as a part of hormonal replacement therapy for preventing endometrial hyperplasia (thickening of the lining of the uterus). It should be taken with food. It should be taken at the same time each day to get the most benefit. You should continue taking it for as long as your doctor has told you to, even if you feel well.
The most common side effects include headache, breast pain, irregular vaginal bleeding or spotting, stomach or abdominal cramps, bloating, nausea and vomiting, hair loss, edema, and vaginal yeast infection. Side effects are more common during the first few weeks and usually lessen as your body gets used to the medicine. You may also experience bleeding or spotting between your periods, consult with your doctor if it happens frequently.
Before taking this medicine, inform your doctor if you have, or have had, breast cancer, unusual bleeding in the vagina, or liver disease. You will probably have several tests both before and during treatment to check your womb. Also, tell your doctor what other medicines you are taking as some may affect, or be affected by, this medicine. In general, it is advisable to avoid alcohol and smoking.
Uses of Profine Soft Gelatin Capsule
Benefits of Profine Soft Gelatin Capsule
In Hormone replacement therapy
Hormone placement therapy (HRT) is a treatment to relieve symptoms of menopause such as hot flushes, night sweats, mood swings, vaginal dryness, and reduced sex drive. Since menopause can last for several years, this treatment can make a big improvement to your daily life and mood. Progesterone is one of two important hormones (the other being is estrogen) used in this treatment. However, it may not treat all your symptoms, consult with your doctor. You should use this medicine as it is prescribed, and for as long as it is prescribed by your doctor.
In Treatment of Female infertility
Profine 100 Soft Gelatin Capsule contains progesterone, a female hormone that is important in the regulation of ovulation and menstruation. It is used to cause menstrual periods in women who have not reached menopause but are not having periods due to a lack of natural progesterone in the body. This medicine helps to prepare the uterus for pregnancy by causing the uterus lining (endometrium) to thicken. This increases the chance of a successful pregnancy. You should use the medicine as prescribed for it to be effective. You may be asked to continue with this treatment for a period after becoming pregnant.
Side effects of Profine Soft Gelatin Capsule
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Profine
- Abdominal pain
- Nausea
- Abnormal vaginal bleeding
- Edema (swelling)
- Hair loss
- Abdominal bloating
- Headache
- Breast pain
- Vomiting
- Vaginal yeast infection
How to use Profine Soft Gelatin Capsule
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Profine 100 Soft Gelatin Capsule is to be taken with food.
How Profine Soft Gelatin Capsule works
Profine 100 Soft Gelatin Capsule is a progesterone (female hormone). It helps to establish and maintain pregnancy. It also prevents the increase in thickness of the endometrium (lining of the uterus) caused by estrogen.
Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Profine 100 Soft Gelatin Capsule. Please consult your doctor.
Pregnancy
SAFE IF PRESCRIBED
Profine 100 Soft Gelatin Capsule is safe to use during pregnancy. Most studies have shown low or no risk to the developing baby.
Breast feeding
SAFE IF PRESCRIBED
Profine 100 Soft Gelatin Capsule is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Driving
UNSAFE
Profine 100 Soft Gelatin Capsule may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
CONSULT YOUR DOCTOR
There is limited information available on the use of Profine 100 Soft Gelatin Capsule in patients with kidney disease. Please consult your doctor.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Profine 100 Soft Gelatin Capsule in patients with liver disease. Please consult your doctor.
What if you forget to take Profine Soft Gelatin Capsule?
If you miss a dose of Profine 100 Soft Gelatin Capsule, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
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Quick tips
- Profine 100 Soft Gelatin Capsule is a natural progesterone available as a micronized formulation which helps in better absorption of this medicine.
- It is used as a part of hormone replacement therapy generally in combination with an estrogen.
- It may also be used in the treatment of problems related to menstrual periods such as amenorrhea (absence of periods).
- It also helps in the maintenance of pregnancy in women who are at higher risk of miscarriage.
- It should be taken with food.
- It may cause sleepiness or drowsiness. If this happens to you, do not drive or use machinery.
Fact Box
Chemical Class
Progesterone Derivative
Habit Forming
No
Therapeutic Class
GYNAECOLOGICAL
Action Class
Natural Progesterone
Interaction with drugs
Taking Profine with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Mycophenolate mofetil may reduce the efficacy of Progesterone (Natural Micronized).
Effective contraception must be used before, during, and for at least 6 weeks after stopping My
Perampanel may reduce the efficacy of Progesterone (Natural Micronized).
It is recommended to use barrier methods (like condoms), IUDs, or a depot for contraception. Your doctor m
If used together, Darunavir may affect blood levels of Progesterone (Natural Micronized).
It is recommended to use barrier methods (like condoms), IUDs, or a depot for contracepti
Concurrent use may increase the risk of formation of blood clots.
If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observatio
Concurrent use may result in contraceptive failure.
It is recommended to use barrier methods (like condoms), IUDs, or a depot for contraception. Your doctor may monitor your treat
Patient concerns
User feedback
What are you using Profine Soft Gelatin Capsule for?
Hormone repla*
100%
*Hormone replacement therapy
How much was the improvement?
Excellent
67%
Average
33%
What were the side-effects while using Profine 100 Soft Gelatin Capsule?
Sleepiness
100%
How do you take Profine Soft Gelatin Capsule?
With food
100%
Please rate Profine 100 Soft Gelatin Capsule on price
Average
100%
FAQs
What is Profine 100 Soft Gelatin Capsule?
Profine 100 Soft Gelatin Capsule is a type of progesterone hormone which is extracted from plants, but its property matches with the human progesterone. This medicine undergoes a process called micronization where the size of the natural progesterone is reduced. The small size of the progesterone particles enhances its dissolution and absorption. This provides better availability of Profine 100 Soft Gelatin Capsule in the body and decreases its side effects.
What is Profine 100 Soft Gelatin Capsule used to treat?
Profine 100 Soft Gelatin Capsule is used to treat various disorders. It is given to women with secondary amenorrhea (no menstruation for 3 months in women who have had their menses before). It is used to support pregnancy, prevent premature labor, and treat bleeding disorders that may occur before menopause. It may be used as a part of fertility treatment and may be given as hormone replacement therapy after menopause. It is also given to relieve symptoms of premenstrual syndrome and painful bleeding like in dysfunctional uterine bleeding.
Can you take Profine 100 Soft Gelatin Capsule every day?
Yes, Profine 100 Soft Gelatin Capsule can be taken every day. It is usually prescribed to be taken once daily in the evening or at bedtime. The usual duration of prescription may vary from 10-12 days a month to 25 days a month. However, the number of days for which you will need to take this medicine in each cycle will be suggested by your doctor depending upon your health condition.
Does Profine 100 Soft Gelatin Capsule cause weight gain?
Yes, taking Profine 100 Soft Gelatin Capsule may cause weight gain. The weight gain may be due to water retention and may not be a serious sign. However, contact your doctor in case your weight gain is worrying you. The risk of weight gain is generally less if Profine 100 Soft Gelatin Capsule is taken with estrogen as a combined pill. But, do not start any hormonal therapy without consulting your doctor.
Is Profine 100 Soft Gelatin Capsule safe?
Yes, Profine 100 Soft Gelatin Capsule is safer as compared to the normal synthetic progesterone. Its smaller size helps the body absorb it easily and reduces the side effects like fluid retention, reduction of HDL cholesterol levels, headaches and mood disturbance.
How is progesterone beneficial for fertility and pregnancy?
Progesterone is a very crucial hormone in fertility. It is the hormone secreted by the ovaries that helps prepare the uterus for pregnancy and maintain it. Profine 100 Soft Gelatin Capsule (natural micronized form of progesterone) is given as a medicine in cases of infertility to support the uterus in preparing itself for the pregnancy and to prevent the abortions in some cases. It is also used to prevent premature labor.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Chrousos GP. The Gonadal Hormones & Inhibitors. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 706-707.
- Medscape. Progesterone (Natural Micronized). [Accessed 03 Apr. 2019] (online) Available from:
- Progesterone. London, UK: Besins Healthcare (UK) Ltd.; 2003 [revised 14 Jul. 2017]. [Accessed 22 Jan. 2019. (online) Available from:
- Apgar S, Greenberg G. Using Progestins in Clinical Practice. Am Fam Physician. 2000;62(8):1839-46. [Accessed 03 Apr. 2019] (online) Available from:
- Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006. Progesterone. [Updated 2022 May 15]. [Accessed 05 Aug. 2023] (online) Available from:
Marketer details
Name: Aristo Pharmaceuticals Pvt Ltd
Address: Mercantile Chamber, 3rd Floor, 12, J.N. Heredia Marg, Ballard Estate, Mumbai – 400 001, India.
Country of origin: India
The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.
The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.
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