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Last updated on:
04 Oct 2019 | 06:48 PM (IST)
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Prime 1000 Tablet SR

Prescription Required

Overview

Introduction of Prime Tablet SR

Prime 1000 Tablet SR is a medicine used in the treatment of type 2 diabetes mellitus. It helps to lower the high blood sugar levels and prevents long-term complications.

Prime 1000 Tablet SR should be used along with a proper diet and regular exercise for best results. It should be taken with food to avoid side effects such as nausea and stomach upset.

Uses of Prime Tablet SR

Prime Tablet SR side effects

Common
  • Nausea
  • Vomiting
  • Taste change
  • Diarrhea
  • Abdominal pain
  • Loss of appetite
Severe
  • Lactic acidosis

How to use Prime Tablet SR

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Prime 1000 Tablet SR is to be taken with food.

How Prime Tablet SR works

Prime 1000 Tablet SR is an anti-diabetic medication (biguanide). It works by lowering glucose production in the liver, delaying sugar (glucose) absorption from intestines and increasing the body's sensitivity to insulin.

Prime Tablet SR related warnings

Alcohol
UNSAFE
It is unsafe to consume alcohol with Prime 1000 Tablet SR Taking metformin with alcohol can cause lactic acidosis and you may experience malaise, respiratory distress, slow or irregular heartbeat, sleepiness, stomach upset, or other unusual symptoms.
Pregnancy
SAFE IF PRESCRIBED
Prime 1000 Tablet SR is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Lactation
SAFE IF PRESCRIBED
Prime 1000 Tablet SR is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving
CAUTION
Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.
Kidney
CAUTION
Prime 1000 Tablet SR should be used with caution in patients with kidney disease. Dose adjustment of Prime 1000 Tablet SR may be needed. Please consult your doctor.
Use of Prime 1000 Tablet SR is, however, not recommended in patients with severe kidney disease. Regular monitoring of kidney function test is advisable while you are taking this medicine.
Liver
CAUTION
Prime 1000 Tablet SR should be used with caution in patients with liver disease. Dose adjustment of Prime 1000 Tablet SR may be needed. Please consult your doctor.
Prime 1000 Tablet SR is generally started with low dose in patients with mild to moderate liver disease and its use is not recommended in patients with severe liver disease.

What if you miss a dose of Prime Tablet SR?

If you miss a dose of Prime 1000 Tablet SR, skip it and continue with your normal schedule. Do not double the dose.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Prime 1000 Tablet SR
₹2.5/Tablet SR
₹4/Tablet SR
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₹3.93/Tablet SR
57% costlier
Glyciphage SR 1gm Tablet
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₹3.99/Tablet SR
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₹3.99/Tablet SR
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Riomet OD 1000mg Tablet SR
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₹3.99/Tablet SR
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Expert Advice

  • You have been prescribed Prime 1000 Tablet SR to control the blood sugar level and reduce the risk of diabetic complications such as heart  attacks.
  • Chances of weight gain and low blood sugar are lesser as compared to other diabetes medicines. 
  • Hypoglycemia (low blood sugar level) may occur when taken along with other antidiabetic medicines, alcohol or on delaying/skipping a meal. Carry a sugar source with you for immediate relief.
  • Tell your doctor immediately if you experience any deep or rapid breathing, persistent nausea, vomiting, and stomach pain as Prime 1000 Tablet SR may cause a rare but serious condition called lactic acidosis, which is an excess of lactic acid in the blood.
  • Vitamin B12 deficiency and symptoms of anemia like fatigue, pale skin, shortness of breath or headache may occur. Notify your doctor if you experience any of these as you may require supplements.
  • Your doctor will monitor your blood sugar levels and kidney functions regularly while taking this medication.

Interaction with Drugs

Taking Prime with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Zencort-M, Welone, Rigapred
SERIOUS
Brand(s): Leparox, Prx
SERIOUS
Brand(s): Nudiglue-C
SERIOUS
Brand(s): Acigo, Ranis
SERIOUS
Brand(s): Densol
SERIOUS
Brand(s): Ducort, Defmark, Zacdef
SERIOUS
Brand(s): Kopram, Ecit, Escnx
SERIOUS
Brand(s): Psycool, Proparise
SERIOUS

Patient Concerns

Questions Related to Prime

arrow
Hi Doctor I have Type 2 diabetes, at present i m taking istamet 50/1000 mg, kindly advise if my medicine can be stopped
Dr. Shikha Mishra
Dietician
Please consult doctor regarding this issue
Sir/madam Diabetes type--Type-2 Diabetes Im taking 1 tablet in morning after TIFFIN. Tablet--GLYCOMET-GP2 FORTE. This 1 tablet sufficient as my Diabetes checkup results.& My liver Mildly enlarged this is my problem so pls expalin only 1 Tablet wii effect on any parts of my body Pls ExplainFBS-170 PPBS-190
Dr. Sanjay Bhatt
Diabetes Specialist
Need to examine and priscribe medicine for you.Without examine , can't priscribe any medicine in your case.so plz consult doctor near by or can visit our clinic
arrow
Do you have any questions related to Prime 1000 Tablet SR?

User Feedback


FAQs

Q. What does Prime do exactly?

People with type 2 diabetes are not able to make enough insulin or respond normally to the insulin made by their bodies. When this happens, the concentration of sugar/glucose increases in the blood. Prime acts in several ways to reduce the increased levels of sugar in blood. Prime decreases the glucose production from the liver, decreases absorption of glucose from the intestine after taking food, and improves the sensitivity of the body organs and muscles to insulin. This helps improve the uptake of glucose from the blood. It helps your body respond better to the insulin it makes naturally.

Q. Does Prime cause weight loss?

Yes, Prime has been shown to reduce weight in people who are sensitive or resistant to insulin, overweight, or obese. The use of Prime may cause modest weight loss in overweight and obese individuals who are at risk for diabetes. But, do not start taking this medicine for weight loss.

Q. What are the benefits of taking Prime?

Prime is one of the first medicines that is given to patients with high blood sugar levels. It helps control the blood sugar. It promotes the body’s response to the insulin made by the pancreas, decreases the amount of sugar made by the liver, and decreases the amount of sugar absorbed by the intestines. Unlike other oral antidiabetic medicines, Prime when taken alone rarely cause low blood sugar as it prevents the pancreas from secreting more insulin. In addition to being a great blood sugar lowering medicine, it also helps control weight gain.

Q. Can Prime make you sleepy?

Prime usually does not cause sleepiness and is well tolerated. However, the use of Prime may rarely cause sleep disorders and insomnia. Sleepiness may be due to a very serious side effect called lactic acidosis, particularly if your kidneys are not working properly. Therefore, you must immediately contact your doctor if you feel sleepy or tired while taking Prime.

Q. How to take Prime?

Take Prime with or after a meal. Do not crush or chew the tablets and swallow it with a glass of water. If your doctor has prescribed one tablet a day, take it in the morning with breakfast. If two tablets a day, then take one in the morning and other in evening with dinner. If you take three doses a day, apart from morning and evening take it with lunch. Taking Prime with meals will reduce its digestive problems like indigestion, nausea, vomiting, diarrhoea, bellyache and loss of appetite.

Related Products

Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
  1. Powers AC, D’Alessio D. Endocrine Pancreas and Pharmacotherapy of Diabetes Mellitus and Hypoglycemia. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. pp. 1258-60.
  2. Nolte MS. Pancreatic hormones and antidiabetic drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 741-42.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 873-75.
  4. Metformin hydrochloride. Princeton, New Jersey: Bristol-Myers Squibb Company. [Accessed 12 Mar. 2019] (online) Available from:External Link
  5. Metformin hydrochloride oral solution. Gloversville, New York: Ranbaxy Pharmaceuticals Inc.; 2003. [Accessed 12 Mar. 2019] (online) Available from:External Link
  6. Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-98. [Accessed 12 Mar. 2019] (online) Available from:External Link
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