Premib 2mg Injection

Written By Dr. Lipika Khurana, PGDHHM, BDS

Reviewed By Dr. Rajeev Sharma, MBA, MBBS

Last updated on 25 Nov 2025 | 03:05 PM (IST)

Premib 2mg Injection is used in the treatment of multiple myeloma and mantle-cell lymphoma. It shows its working by stopping or slowing down the growth of cancer cells.

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General Information

Contains

Bortezomib (2mg)

Marketer

Premedium Pharmaceuticals Pvt Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Premib 2mg Injection is given as an injection by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

Fatigue, nausea, vomiting, and loss of appetite are some common side effects of this medicine. You may be advised to drink plenty of fluids every day during the treatment. You should not drive or operate machinery as medicine may cause tiredness and dizziness. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with heart, liver, and blood uric acid levels.

Before taking Premib 2mg Injection, consult with your doctor if you have any liver, kidney, heart disease or bleeding problem. It is important to consult a doctor if you develop symptoms like memory loss or trouble in thinking. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

Uses of Premib Injection

Benefits of Premib Injection

Multiple myeloma
Premib 2mg Injection is used in multiple myeloma to help control the growth of abnormal plasma cells in the bone marrow, reduce symptoms, and improve response to treatment.

Mantle-cell lymphoma
In mantle-cell lymphoma, Premib 2mg Injection is used to slow the progression of the disease, reduce tumor burden, and enhance the effectiveness of combination cancer therapies.

Side effects of Premib Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Premib

Breathlessness
Gastrointestinal bleeding
Fungal infection
Anemia (low number of red blood cells)
Decreased white blood cell count (neutrophils)
High blood pressure
Itching
Herpes zoster
Pneumonia
Motor neuropathy
Orthostatic hypotension (sudden lowering of blood pressure on standing)
Dry skin
Edema (swelling)
Decreased white blood cell count (lymphocytes)
Lymphopenia
Decreased potassium level in blood
Decreased sodium level in blood
Decreased calcium level in blood
Erythema (skin redness)
Dehydration
Low blood platelets

How to use Premib Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Premib Injection works

Premib 2mg Injection is an anti-cancer medication. It works by blocking or slowing the breakdown of proteins in cells. As a result, there is an increase in a number of proteins in the cancer cells leading to their death.

All substitutes for Premib 2mg Injection

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

Premib 2mg Injection is given as an injection into veins or skin under the supervision of a healthcare professional.
Do not skip any dose and complete the course as suggested by your doctor.
Use an effective method of birth control to avoid pregnancy while taking this medication.
You may need to have blood tests to monitor your blood cells, platelets count, liver function and kidney function during treatment.
Inform your doctor immediately if you experience coughing, shortness of breath and swelling of feet.
Premib 2mg Injection is given as an injection into veins or skin under the supervision of a healthcare professional.
Do not skip any dose and complete the course as suggested by your doctor.
Use an effective method of birth control to avoid pregnancy while taking this medication.
You may need to have blood tests to monitor your blood cells, platelets count, liver function and kidney function during treatment.
Inform your doctor immediately if you experience coughing, shortness of breath and swelling of feet.

Safety advice

Alcohol

UNSAFE

Do not drink alcohol while you are taking this medicine. Premib 2mg Injection may cause excessive drowsiness when taken with alcohol.

Pregnancy

CONSULT YOUR DOCTOR

Premib 2mg Injection is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding

UNSAFE

Premib 2mg Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving

UNSAFE

Premib 2mg Injection may cause side effects that could affect your ability to drive.
Premib 2mg Injection might cause tiredness, dizziness, fainting, or blurred vision which may affect your ability to drive.

Kidney

CAUTION

Premib 2mg Injection should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.

Liver

CAUTION

Premib 2mg Injection should be used with caution in patients with liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Premib with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Severe

Carbamazepine (Oral Route)

Avoid concurrent use. Please consult with your doctor. Carbamazepine may reduce efficacy of Bortezomib.

Severe

Enzalutamide (Oral Route)

Avoid concurrent use. Please consult with your doctor. Enzalutamide may reduce efficacy of Bortezomib.

Severe

Fosphenytoin (Injection Route)

Avoid concurrent use. Please consult with your doctor. Fosphenytoin may reduce efficacy of Bortezomib.

Severe

Phenytoin (Oral Route)

Avoid concurrent use. Please consult with your doctor. Phenytoin may reduce efficacy of Bortezomib.

Severe

Phenytoin (Injection Route)

Avoid concurrent use. Please consult with your doctor. Phenytoin may reduce efficacy of Bortezomib.

Frequently asked questions

When should I call my doctor right away?

Get medical help right away if you have muscle cramping, muscle weakness, confusion, visual loss or disturbances, blindness, seizures, headaches, shortness of breath, swelling of your feet or changes in your heartbeat, high blood pressure, tiredness, fainting, coughing and breathing difficulties or tightness in the chest.

How will you know that Premib 2mg Injection is working?

Keep taking this medicine exactly as directed until your doctor tells you to stop. Regular scans will reveal whether your tumor is responding to the treatment. Your doctor will determine when those scans should be scheduled.

What precautions should I take to reduce the chances of getting infected during treatment with Premib 2mg Injection?

Since Premib 2mg Injection lowers the number of white blood cells and platelets in your blood, it puts you at risk of getting an infection or bleeding. In order to prevent, avoid people who have infections. Check with your doctor immediately if you think you may be getting an infection, or if you get a fever, chills, cough; be careful not to cut yourself when you are using sharp objects such as a razor or nail cutters, and use a toothbrush with soft bristles to prevent bleeding from gums.

Can Premib 2mg Injection be used during pregnancy?

No, this medicine should not be used during pregnancy as it can harm your unborn baby. Avoid getting pregnant and use an effective method of birth control during your treatment and for at least 3 months after the last dose of Premib 2mg Injection.

Can Premib 2mg Injection affect my lungs? What should I do?

Yes, this medicine might cause potentially fatal problems in your lung. If you feel severe shortness of breath, confusion, dry cough, dizziness, or extreme tiredness, talk to your doctor right away.

Does Premib 2mg Injection cause hair loss?

Yes, while taking this medicine, your hair may become brittle and break. You may also experience patchy hair loss or thinning. These conditions tend to resolve once treatment is stopped. Be gentle when brushing and washing hair to manage hair loss.

Are there any precautions for tingling sensation and numbness in my arms and legs?

This medicine causes tingling, numbness, pain, or burning sensation in your arms or legs. Be careful when moving around, as the numbness may make it harder to walk, feel your hands or feet, or increase your risk of falls. Talk to your doctor if you feel these symptoms. You may need to change your dose or schedule.

I have noticed some changes in my skin after taking Premib 2mg Injection? What should I do?

Use a moisturizer to get relief from rashes, dry and itchy skin. Avoid direct sunlight, wear protective clothing, and use sunscreen with (SPF more than 15) whenever you step outdoors. Do not go swimming if you have a rash because the chlorine in the water can make it worse. Avoid hot water bath and wear loose and cotton fabric clothes. Your skin will tend to become better once treatment is stopped.

How to relieve constipation during the treatment?

To relieve constipation, include fiber in your diet (fruits and vegetables), drink 8-10 glasses of fluids a day, and keep active. A stool softener (with a doctor's prescription) once or twice a day may prevent constipation. If you do not have a bowel movement for 2-3 days, consult your doctor.

I am experiencing nausea and extreme tiredness. Is this due to Premib 2mg Injection?

Nausea and fatigue or tiredness are some of the common side-effects of this medicine. Eat smaller, more frequent meals to reduce the feeling of nausea. Avoid food that is salty, spicy, fried, or fatty. Take plenty of rest and do light exercise daily to keep yourself active and reduce fatigue.

I am noticing a change in my taste. How shall I improve my taste?

You may experience a metallic taste or find that food has no taste at all. You may dislike foods or beverages that you liked before receiving cancer treatment. Rinse your mouth with a solution of salt and bicarbonate of soda before mealtimes to neutralize the bad taste in your mouth. You can also add extra flavor or seasonings to your food.

Fact Box

Chemical Class

Phenylalanine derivative

Habit Forming

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Proteasome Inhibitors

Related lab tests

Albumin/Globulin Ratio, Serum

Calcium

Complete Blood Count

Cyclin D1

Kidney Function Test

References

Chabner BA, Barnes J, Neal J, et al. Targeted Therapies: Tyrosine Kinase Inhibitors, Monoclonal Antibodies, and Cytokines. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1742-43.
Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 958.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 153-54.
Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:
Bortezomib. Beerse Belgium: Janssen Pharmaceutica NV; [Accessed 26 Mar. 2019] (online) Available from:
Bortezomib [Prescribing Information]. Cambridge, MA: Millennium Pharmaceuticals, Inc.; 2008. [Accessed 25 Jul. 2024] (online) Available from:

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Premedium Pharmaceuticals Pvt Ltd
Address: 207 SUCHET CHAMBERS, 1224/5 BANK STREET, KAROL BAGH, NEW DELHI Central Delhi DL 110005 IN

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Premib 2mg Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

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Why we need a prescription?

Provide right medicines

Prescriptions are complex documents. We proof read and recheck at various steps to provide you the right medication in the correct form and dose

In accordance with the law

Most medicines cannot be sold without a valid prescription, as per the Drugs and Cosmetics Act, 1940 and Rules, 1945

Premib 2mg Injection

Save more with additional offers

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General Information

Contains

Marketer

Storage

Product introduction

Uses of Premib Injection

Benefits of Premib Injection

Side effects of Premib Injection

How to use Premib Injection

How Premib Injection works

All substitutes for Premib 2mg Injection

Bortenat 2mg Injection

Myezom 2mg Injection

Borviz 2mg Injection

Bortecad 2mg Injection

Bortetrust 2 Injection

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Carbamazepine (Oral Route)

Enzalutamide (Oral Route)

Fosphenytoin (Injection Route)

Phenytoin (Oral Route)

Phenytoin (Injection Route)

Frequently asked questions

When should I call my doctor right away?

How will you know that Premib 2mg Injection is working?

What precautions should I take to reduce the chances of getting infected during treatment with Premib 2mg Injection?

Can Premib 2mg Injection be used during pregnancy?

Can Premib 2mg Injection affect my lungs? What should I do?

Does Premib 2mg Injection cause hair loss?

Are there any precautions for tingling sensation and numbness in my arms and legs?

I have noticed some changes in my skin after taking Premib 2mg Injection? What should I do?

How to relieve constipation during the treatment?

I am experiencing nausea and extreme tiredness. Is this due to Premib 2mg Injection?

I am noticing a change in my taste. How shall I improve my taste?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Albumin/Globulin Ratio, Serum

Calcium

Complete Blood Count

Cyclin D1

Kidney Function Test

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

In case of any issues, contact us

Lab tests offered by us

Related/Popular tests