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Plugclar 500mg Injection

Written By Dr. Anuj Saini, MMST, MBBS
Reviewed By Dr. Rajeev Sharma, MBA, MBBS
Last updated on 31 Mar 2026 | 02:31 PM (IST)
Plugclar 500mg Injection is an antibiotic used to treat various types of bacterial infections. It is effective in most infections of the respiratory tract, ear, nose, throat, lungs, and skin. It is also effective against some infections seen in people with reduced immunity.
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General Information

The content is shown in English
Plugclar 500mg Injection image
Plugclar 500mg Injection image

Product introduction

Plugclar 500mg Injection is also effective against some infections (e.g., MAC or Mycobacterium avium complex) seen in people with reduced immunity. It stops the bacteria from growing, which helps to resolve your symptoms and cure your infection. This medicine is taken orally, preferably either one hour before or 2 hours after a meal. No antacids should be taken within 2 hours of taking this medicine. It should be used regularly at evenly spaced time intervals as prescribed by your doctor. Do not skip any doses and finish the full course of treatment even if you feel better. Stopping the medicine too early may lead to the infection returning or worsening.

Common side effects with this medicine include diarrhea, nausea, abnormal taste, indigestion, abdominal pain, headache, vomiting, and rash. These are usually temporary and subside with the completion of treatment. Consult your doctor if you find these side effects do not resolve or persist for a longer duration.

Inform your doctor if you have any previous history of allergy or heart problems before taking this medicine. Pregnant or breastfeeding women should consult their doctor before using this medicine.

Uses of Plugclar Injection

Benefits of Plugclar Injection

Treatment of Bacterial infections
Plugclar 500mg Injection is an antibiotic medicine that can be used to treat many different infections caused by bacteria. These include infections of the respiratory tract, ear, nose, throat, lungs, and skin. It is also effective against a bacteria known as H. pylori, which is associated with peptic ulcer disease. It stops further growth of the bacteria causing the infection and helps treat your infection.

This medicine usually makes you feel better quite quickly. However, you should continue taking it as long as it is prescribed even when you feel better, to make sure that all bacteria are killed and do not become resistant.

Side effects of Plugclar Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Plugclar
  • Sweating
  • Swelling
  • Rash
  • Nausea
  • Vomiting
  • Headache
  • Injection site phlebitis
  • Insomnia (difficulty in sleeping)
  • Abnormal taste
  • Dyspepsia
  • Taste change
  • Abnormal liver function tests
  • Abdominal pain
  • Diarrhea

How to use Plugclar Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Plugclar Injection works

Plugclar 500mg Injection is an antibiotic. It works by preventing synthesis of essential proteins required by bacteria to carry out vital functions. Thus, it stops the bacteria from growing, and prevents the infection from spreading.

Quick tips

  • Your doctor has prescribed Plugclar 500mg Injection to cure your infection and improve your symptoms.
  • It is given as a drip under the supervision of a healthcare provider.
  • Do not skip any doses and finish the full course of treatment even if you feel better. Stopping it early may make the infection to come back and harder to treat.
  • Diarrhea may occur as a side effect but should stop when your course is complete. Inform your doctor if it doesn't stop or if you find blood in your stools.
  • Stop taking Plugclar 500mg Injection and inform your doctor immediately if you develop an itchy rash, swelling of the face, throat or tongue or breathing difficulties while taking it.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Plugclar 500mg Injection. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Plugclar 500mg Injection during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Information regarding the use of Plugclar 500mg Injection during breastfeeding is not available. Please consult your doctor.
Driving

Driving

CONSULT YOUR DOCTOR
It is not known whether Plugclar 500mg Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.
Kidney

Kidney

CAUTION
Plugclar 500mg Injection should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Liver

Liver

CAUTION
Plugclar 500mg Injection should be used with caution in patients with liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Plugclar with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Life-threatening

Pimozide (Oral Route)

Do not consume Pimozide with Clarithromycin.
Life-threatening

Domperidone (Oral Route)

Do not consume Domperidone with Clarithromycin.
Life-threatening

Simvastatin (Oral Route)

Do not consume Simvastatin with Clarithromycin. If Clarithromycin is essential, your doctor may temporarily stop Simvastatin. Clarithromycin may raise blood levels of Simvastatin.
Life-threatening

Ivabradine (Oral Route)

Do not consume Ivabradine with Clarithromycin. Clarithromycin may raise blood levels of Ivabradine.
Life-threatening

Dronedarone (Oral Route)

Do not consume Dronedarone with Clarithromycin.

Frequently asked questions

This medicine is an antibiotic that is used for the treatment of pneumonia, bronchitis, throat and sinus, skin infections, and ear infections. It can also be used with other medications to treat stomach ulcers caused by bacteria.
Plugclar 500mg Injection treats your infection by stopping bacteria from producing important nutrients it needs to survive.
For most infections, you might start to feel better within a few days. Other infections, like stomach ulcers (due to bacteria) or skin infections, might take a little longer to feel better. It is very important to keep taking this medicine for as long as your doctor has prescribed, even if you start to feel better.
No, Plugclar 500mg Injection should not be used to treat UTIs. Consult your doctor who can prescribe you the exact medication for treating your urinary tract infection.
No, it is advisable not to take an antacid along with Plugclar 500mg Injection. If you have to take an antacid containing aluminum and/or magnesium, make sure that you take it at least 2 hours before or after taking Plugclar 500mg Injection. Talk to your doctor in case of any doubts.
There are no studies confirming the effect of this medicine on birth control pills. However, it is better to consult your doctor who can advise you more on this.
Nausea and vomiting are some of the common side-effects of this medicine. Eat smaller, more frequent meals to reduce the feeling of nausea. Avoid food that is salty, spicy, fried, or fatty, and drink plenty of water.
Seek immediate medical help if you get a faster or irregular heartbeat, severe pain in your stomach or back, blood and mucus in stool, dark urine, and stool.
No, although amoxicillin and clarithromycin are both antibiotics, they are not the same. They target different bacteria in your body and can be used for treating different infections. Your doctor will decide which antibiotic is best for you based on your infection and types of symptoms.

Fact Box

Chemical Class

Aminoglycosides

Habit Forming

No

Therapeutic Class

ANTI INFECTIVES

Action Class

Macrolides

References

  1. Chambers HF, Deck DH. Tetracyclines, Macrolides, Clindamycin, Chloramphenicol, Streptogramins, & Oxazolidiones. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 800-801.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 287-89.
  3. Clarithromycin. Via Fossignano, Italy: Ibigen Srl,; 2012 [revised 6 Mar. 2018]. [Accessed 31 Mar. 2019] (online) Available from:
  4. Clarithromycin [New Zealand Data Sheet]. Pt Chevalier, Auckland: Max Health Ltd.; 2022. [Accessed 06 Apr. 2023] (online) Available from:
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Samarth Life Sciences Pvt Ltd
Address: Samarth House, 168, Bangur Nagar, Off Link Road, Near Ayappa Temple & Kallol Kali Temple, Goregaon (W), Mumbai - 400 090.

Vendor Details

Country of origin: India
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