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Ivabradine

Information

Uses

Ivabradine is used in the treatment of angina and heart failure.

How it works

Ivabradine lowers the heart rate which, in turn, reduces the oxygen requirement of the heart. As a result, the heart works more efficiently.

Common side effects

Slow heart rate, Headache, Luminous phenomena (Enhanced brightness)

Available Medicine

  • ₹135 to ₹200
    Lupin Ltd
    3 variant(s)
  • ₹169 to ₹225
    Abbott India Ltd
    2 variant(s)
  • ₹39 to ₹153
    Sun Pharmaceutical Industries Ltd
    2 variant(s)
  • ₹129 to ₹159
    Torrent Pharmaceuticals Ltd
    2 variant(s)
  • ₹146
    Macleods Pharmaceuticals Pvt Ltd
    1 variant(s)
  • ₹275 to ₹333
    Serdia Pharmaceuticals India Pvt Ltd
    2 variant(s)
  • ₹169 to ₹193
    Unichem Laboratories Ltd
    2 variant(s)
  • ₹145
    Cipla Ltd
    1 variant(s)
  • ₹120 to ₹149
    Zydus Cadila
    2 variant(s)
  • ₹110 to ₹140
    Biocon
    2 variant(s)

Expert advice

  • Notify your doctor if there is a change in vision (such as brief increased brightness or colored bright lights). It usually starts within the first 2 months of taking the medicine. It may later go away during the treatment or after stopping the medication. 
  • Notify your doctor if you have any liver problem or heart disease such as sick sinus syndrome (sinus dysfunction), heart blockage and pacemaker use. 
  • Avoid driving if you feel dizzy or experience a change in the vision, after consuming Ivabradine. 
  • Notify your doctor immediately if you are or are planning to become pregnant during the administration of this medicine. 
  • Do not breast-feed while taking Ivabradine.

Frequently asked questions

Ivabradine

Q. What is ivabradine used for?
Ivabradine is a heart medicine used in adult patients to treat symptomatic stable angina pectoris (chest pain) and chronic heart failure.
Q. How does ivabradine work in heart failure?
Chronic heart failure is a heart disease which happens when your heart cannot pump enough blood to the rest of your body. Ivabradine mainly works by reducing the heart rate a few beats per minute. As increased heart rate affects the heart functioning in patients with chronic heart failure, the specific heart rate lowering action of ivabradine helps to improve the heart functioning and survival in these patients
Q. How does ivabradine reduce angina?
Angina is a heart disease which happens when the heart does not receive enough oxygen. Ivabradine mainly works by reducing the heart rate a few beats per minute. This lowers the work of heart and heart's need for oxygen especially in the situations when an angina attack is more likely to happen. In this way, ivabradine helps to control and reduce the number of angina attacks.
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Q. Does ivabradine lower blood pressure?
Ivabradine can lower blood pressure, although it is an uncommon side effect. Uncontrolled blood pressure is a common side effect of ivabradine. Please consult your doctor before taking ivabradine if you suffer from mild to moderate low blood pressure or if you suffer from uncontrolled blood pressure, especially after a change in your treatment for blood pressure.
Q. Does ivabradine cause long QT interval?
Ivabradine causes a decrease in heart rate which may cause QT prolongation, giving rise to severe arrhythmias (condition in which the heart beats with an irregular or abnormal rhythm) especially torsades de pointes.
Q. Is ivabradine a beta blocker?
Ivabradine is not a beta blocker. Ivabradine lowers heart rate by inhibition of the cardiac pacemaker funny (If) current that regulates heart rate, a mechanism different from that of beta blockers.
Q. Is ivabradine safe?
Ivabradine is safe if used at prescribed doses for the prescribed duration as advised by the doctor.
Q. Is ivabradine Food and Drug Administration (FDA) approved?
Yes, ivabradine is approved by Food and Drug Administration (FDA).
Q. Is ivabradine a calcium channel blocker?
Ivabradine is not a calcium channel blocker. Ivabradine lowers heart rate by inhibition of the cardiac pacemaker funny (If) current that regulates heart rate.

Content on this page was last updated on 08 May, 2017, by Dr. Varun Gupta (MD Pharmacology)