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    Information about Simvastatin

    Simvastatin uses

    Simvastatin is used in the treatment of high cholesterol.

    How simvastatin works

    Simvastatin is a lipid-lowering medication (statin). It works by blocking an enzyme (HMG-CoA-reductase) that is required in the body to make cholesterol. It thus lowers "bad" cholesterol (LDL), triglycerides and raises "good" cholesterol (HDL).

    Common side effects of simvastatin

    Headache, Stomach pain, Constipation, Feeling sick, Muscle pain, Weakness, Dizziness, Increased glucose level in blood
    Content Details
    Written By
    Dr. Betina Chandolia
    Writing in Sciences, PGCCL
    Reviewed By
    Dr. Ashish Ranjan
    MBA (General management), MD (Clinical Pharmacology)
    Last updated on:
    08 Jan 2019 | 02:57 PM (IST)
    Want to know more?
    Read Our Editorial Policy

    Available Medicine for Simvastatin

    • ₹78 to ₹300
      Sun Pharmaceutical Industries Ltd
      4 variant(s)
    • ₹62 to ₹155
      USV Ltd
      4 variant(s)
    • ₹53 to ₹97
      Ipca Laboratories Ltd
      2 variant(s)
    • ₹108
      Akumentis Healthcare Ltd
      1 variant(s)
    • ₹45 to ₹83
      Bal Pharma Ltd
      2 variant(s)
    • ₹44 to ₹99
      Micro Labs Ltd
      3 variant(s)
    • ₹172 to ₹210
      MSD Pharmaceuticals Pvt Ltd
      2 variant(s)
    • ₹43
      Aretaeus Pharmaceuticals
      1 variant(s)
    • ₹25 to ₹76
      Themis Medicare Ltd
      3 variant(s)
    • ₹57
      Comed Chemicals Ltd
      1 variant(s)

    Expert advice for Simvastatin

    • Simvastatin treats high cholesterol by lowering "bad" cholesterol (LDL) and triglycerides (fats). It should be taken in addition to regular exercise and low-fat diet.
    • It also reduces the risk of heart attack and stroke.
    • In general, Simvastatin is safe. It may cause diarrhea, gas or an upset stomach. If any of these happen to you, take it with food.
    • Inform your doctor if you experience fatigue, muscle weakness or muscle pain. 
    • Your doctor may monitor your liver function before starting the treatment and regularly thereafter. Inform your doctor if you notice signs of liver problem such as yellowing of skin or eyes, unusually dark urine or stomach pains.
    • Inform your doctor if you have kidney disease, liver disease or diabetes. If you are diabetic, monitor your blood sugar level regularly as Simvastatin may cause an increase in your blood sugar level.
    • Do not take Simvastatin if you are pregnant or planning to conceive.

    Frequently asked questions for Simvastatin


    Q. What should I know about high cholesterol?

    Cholesterol is a type of fat present in your blood. Your total cholesterol is made up of LDL and HDL cholesterol. LDL cholesterol is called “bad” cholesterol as it can build up in the wall of your blood vessels and slow or obstruct blood flow to your heart, brain, and other organs. This can cause heart diseases and stroke. HDL cholesterol is called “good” cholesterol as it prevents the bad cholesterol from building up in the blood vessels. Triglycerides also are harmful fats found in your blood.

    Q. Is simvastatin a blood thinner or a beta blocker or steroid or diuretic or is it a statin or does simvastatin thin your blood?

    No, simvastatin is a statin (lipid-lowering agents) or HMG CoA reductase inhibitors

    Q. Is simvastatin the same as Lipitor (atorvastatin) or Crestor (rosuvastatin) or pravastatin?

    No, although it belongs to same group of medications called statins

    Q. Can I take simvastatin with ibuprofen or lisinopril?

    No results found for any interaction of simvastatin with ibuprofen or lisinopril, but always consult with your doctor before taking this medication

    Q. Can I take antibiotics or clarithromycin or amoxicillin or erythromycin or amlodipine or aspirin with simvastatin?

    No, do not take antibiotics or clarithromycin or amoxicillin or erythromycin or amlodipine or aspirin with simvastatin, because they interact with each other

    Q. Does Simvastatin cause hair loss or dry mouth or hair loss or constipation or diabetes or depression or it makes you high?

    No. Simvastatin does not cause hair loss or dry mouth or hair loss or constipation or diabetes or depression and it is not addictive

    Q. Does Simvastatin cause joint pain or makes you tired?

    Yes, sometimes Simvastatin may cause joint pain or make you tired.

    Content on this page was last updated on 08 January, 2019, by Dr. Varun Gupta (MD Pharmacology)