Pioli 30mg Tablet is a medicine used to treat type 2 diabetes mellitus in adults. It helps control blood sugar levels in people with diabetes. This helps to prevent serious complications of diabetes like kidney damage and blindness.

Pioli 30mg Tablet may be used by itself or along with other medicines. It may be taken with or without food. Take it regularly at the same time each day to get the most benefit. Your doctor will decide what dose is best for you and this may change from time to time according to how it is working.

Keep taking this medicine, even if you feel well or your blood sugar levels are controlled. If you stop it without consulting your doctor, your blood sugar levels could rise and put you at risk of kidney damage, blindness, nerve problems, and loss of limbs. Remember that it is only part of a treatment program that should also include a healthy diet, regular exercise, and weight reduction as advised by your doctor. Your lifestyle plays a big part in controlling diabetes.

The most common side effects of taking this medicine include headache, sinusitis, muscle pain, and pharyngitis. Consult your doctor if any of these side effects bother you or persist for a longer duration.

You should not take it if you have type 1 diabetes mellitus, if you have diabetic ketoacidosis (high levels of acid in your blood), or if you have severe kidney or liver disease. Before taking this medicine, tell your doctor if you have ever had heart disease, thyroid disease, or some hormonal conditions. It may not be suitable. Pregnant or breastfeeding women should also consult their doctor before taking it. Your blood sugar levels should be checked regularly and your doctor may also advise blood tests to monitor your blood cell counts and liver function.

Uses of Pioli Tablet

Type 2 diabetes mellitus

Side effects of Pioli Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Pioli

Headache
Sore throat
Sinus inflammation
Muscle pain

How to use Pioli Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Pioli 30mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Pioli Tablet works

Pioli 30mg Tablet is an anti-diabetic medication. It works by increasing the body's sensitivity to insulin, a natural substance that helps control blood sugar levels.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Pioli 30mg Tablet.

Pregnancy

CONSULT YOUR DOCTOR

Pioli 30mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

CAUTION

Pioli 30mg Tablet should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.
Monitor the breastfed baby’s blood sugar during treatment with Pioli 30mg Tablet

Driving

SAFE

Pioli 30mg Tablet does not usually affect your ability to drive.

Kidney

SAFE IF PRESCRIBED

Pioli 30mg Tablet is safe to use in patients with kidney disease. No dose adjustment of Pioli 30mg Tablet is recommended.

Liver

CAUTION

Pioli 30mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Pioli 30mg Tablet may be needed. Please consult your doctor.
Use of Pioli 30mg Tablet is not recommended in patients with severe liver disease.

What if you forget to take Pioli Tablet?

If you miss a dose of Pioli 30mg Tablet, skip it and continue with your normal schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Pioli 30mg Tablet

₹3.6/Tablet

Pioz 30 Tablet

USV Ltd

₹12.08/tablet

236% costlier

Piosys 30 Tablet

Systopic Laboratories Pvt Ltd

₹3.4/tablet

6% cheaper

Pioglit 30 Tablet

Sun Pharmaceutical Industries Ltd

₹11.5/tablet

219% costlier

Pionorm 30 Tablet

Micro Labs Ltd

₹9.21/tablet

156% costlier

Piokind 30 Tablet

Mankind Pharma Ltd

₹9.71/tablet

170% costlier

View all substitutes

Quick tips

Pioli 30mg Tablet helps to control blood sugar level and avoid long-term complications.
Take it only as per dose and duration suggested by your doctor.
You should continue to exercise regularly, eat a healthy diet, and take your other diabetes medicines along with Pioli 30mg Tablet.
Full effects may be visible after several weeks of starting Pioli 30mg Tablet. Keep taking it as prescribed by your doctor.
Monitor your blood sugar level regularly while taking this medicine.
Notify your doctor if you experience shortness of breath, heart problems, or any abnormal swelling.
Your doctor may monitor your liver function. Inform your doctor if you notice symptoms like abdominal pain, yellowing of eyes and loss of appetite.
Pioli 30mg Tablet helps to control blood sugar level and avoid long-term complications.
Full effects may be visible after several weeks of starting Pioli 30mg Tablet. Keep taking it as prescribed by your doctor.
Weight gain, headache, and swelling due to fluid build-up may occur.
Notify your doctor if you experience shortness of breath, heart problems, or any abnormal swelling.
May not be suitable for patients with a history of heart failure or bladder cancer.
You should continue to exercise regularly, eat a healthy diet, and take your other diabetes medicines along with Pioli 30mg Tablet.
Take it only as per dose and duration suggested by your doctor.
Monitor your blood sugar level regularly while taking this medicine.
Your doctor may monitor your liver function. Inform your doctor if you notice symptoms like abdominal pain, yellowing of eyes and loss of appetite.

Fact Box

Chemical Class

Thiazolidinedione Derivative

Habit Forming

Therapeutic Class

ANTI DIABETIC

Action Class

Thiazolidinediones (TZD) and PPAR Gamma Agonists

Interaction with drugs

Taking Pioli with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Disopyramide (Oral Route) Severe

Concurrent use may increase the risk of low blood sugar levels. Elderly, malnourished, diabetic individuals and those with kidney and heart dysfunction are at higher risk. If conc... More

Asparaginase (Oral Route) Moderate

Concurrent use may interfere with control over blood sugar. Your doctor may monitor your diabetic control closely and adjust the doses as per the observations.

Clopidogrel (Oral Route) Moderate

Clopidogrel may raise blood levels of Pioglitazone. watch out for symptoms of Pioglitazone side effects such as headache, nausea, dizziness or weakness and consult your doctor if ... More

Chloroquine (Oral Route) Moderate

Concurrent use may increase the risk of low blood sugar levels. Monitor your blood glucose levels regularly and talk to your doctor if you notice any abnormal or unexpected change... More

Mifepristone (Oral Route) Moderate

Mifepristone may raise blood levels of Pioglitazone. watch out for symptoms of Pioglitazone side effects such as headache, nausea, dizziness or weakness and consult your doctor if... More

View all drug interactions

Patient concerns

Diabetes mellitus type 2 ,thirst

Dr. Sanjay Bhatt

Physician

A person can control his or her sugar levels by doing regular exercise and walk or regular aerobic exercises at least 30 to 45 minutes per day.MEDICAL NUTRITIONAL THERAPY THAT IS TO MAINTAIN CALORIES INTAKE AS PER BMI .TAKE HELP OF DIABETIC EDUCATOR. VISIT YOUR DOCTOR AND FOLLOW ALL WHAT DOCTOR SUGGESTED.IN TIME ALL ROUTINE INVESTIGATIONS SHOULD BE DONE.you should not treat it as disease but a start of a healthy life.Uncontrolled sugar levels for long time leads to lower limb weakness which is neuropathy and which is followed by foot ulcers and other complications like kidney or heart problems .online prescription is not allowed without seeing pt.so contact doctor nearby for any change or dose adjustment or visit my clinic at gurgaon sector 52 RdCity snergy multi speciality clinic near SRS MARKET

Diabetes mellitus type 2 required only ayurvedic medicine

Dr. Sanjay Bhatt

Physician

Go for allopathic medicine

Any latest discoveris for type 1 mellitus Diabetes?

Dr. Sanjay Bhatt

Physician

Diabetes Ireland is delighted to hear of the Harvard success and congratulate Professor Melton and colleagues on figuring out the complex series of steps necessary to turn stem cells into beta cells. Hopefully, they can negotiate the regulations for mass production so that an abundant supply of beta cells is available an new and innovative methods will be developed to cure/treat Type 1 diabetes. Type I diabetes is an autoimmune condition whereby the body kills off its own beta (insulin producing) cells resulting in the need for daily insulin administration through the skin. Replacing beta cells in the first step towards a cure, but the replaced beta cells need to be protected from the body?s autoimmune response. This means protecting them in a coating or taking drugs to prevent the response (possible worse side effects than diabetes).

How to manage diabetes mellitus

Dr. Sanjay Bhatt

Physician

A person can control his or her sugar levels by regular exercise and walk or regular aerobic exercises at least 30 to 45 minutes per day.MEDICAL NUTRITIONAL THERAPY THAT IS TO MAINTAIN CALORIES INTAKE AS PER BMI .TAKE HELP OF DIABETIC EDUCATOR. VISIT YOU DOCTOR AND LOW ALL WHAT DOCTOR SUGGESTED.IN TIME ALL ROUTINE INVESTIGATIONS SHOULD BE DONE.you souls not treat it as disease but start of a healthy life.Uncontrolled sugar levels for long time leads to lower limb weakness which is neuropathy and which is followed by foot ulcers and other complications.online prescription is not allowed without seeing pt.so contact doctor nearby for any change or dose adjustment or visit my clinic at gurgaon sector 52 RdCity snergy multi speciality clinic near SRS MARKET

FAQs

Can Pioli 30mg Tablet cause weight gain?

Pioli 30mg Tablet commonly causes weight gain which may be dose-related. The reason for this weight gain could be fat accumulation. However, in heart failure patients it could be due to water retention in the body. Therefore, it is important to monitor weight in heart failure cases.

Can Pioli 30mg Tablet cause heart failure?

Pioli 30mg Tablet can cause fluid retention which may aggravate or speed up heart failure. The doctor usually starts with the lowest available dose and increases the dose gradually while treating patients who have at least one risk factor for heart failure (previous heart attack, coronary artery disease, elderly). Heart failure is more common when Pioli 30mg Tablet is used with insulin.

Can you take Pioli 30mg Tablet and metformin together?

Yes, Pioli 30mg Tablet can be used with metformin where sufficient blood sugar management was not possible with metformin alone. This combination of medicines can be used in adult patients with type 2 diabetes mellitus and overweight patients with poor blood sugar control.

What time of day should you take Pioli 30mg Tablet?

It is usually prescribed once daily and can be taken at any time of the day but preferably at the same time each day. It can be taken with or without food. You should take Pioli 30mg Tablet exactly as prescribed by your doctor.

How long do I need to take Pioli 30mg Tablet? Can I stop the medicine for some time?

Continue taking Pioli 30mg Tablet as long as your doctor recommends taking it. Treatment for diabetes mellitus is long-term so you may have to take it lifelong. However, if you have to stop it then consult with your doctor who will suggest an alternative. Do not stop taking it without consulting your doctor as it may cause blood sugar levels to rise, which could be harmful to you.

Does Pioli 30mg Tablet affect liver?

Yes, Pioli 30mg Tablet may cause an increase in liver enzymes, and treatment with Pioli 30mg Tablet should be stopped if liver enzymes increase. Hence, levels of liver enzymes should be periodically checked while on treatment with this medicine. Pioli 30mg Tablet should not be prescribed to patients with liver disease.

What kind of medicine is Pioli 30mg Tablet? Is it like metformin?

Pioli 30mg Tablet belongs to the thiazolidinediones class of anti-diabetic medicines. It helps control blood sugar levels by improving how your body uses a hormone called insulin. This is done by helping your cells become more sensitive to the insulin your body makes.

Can Pioli 30mg Tablet cause bladder cancer?

Pioli 30mg Tablet may increase the risk of bladder cancer, though it is very rare. Immediately consult your doctor if you experience blood in your urine, pain when urinating or a sudden need to urinate, during treatment with this medicine. Pioli 30mg Tablet should not be used in patients with a prior history of bladder cancer or having bladder cancer.

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Related lab tests

Glucose - Fasting Blood

Glucose - Postprandial Blood

Glycosylated Hemoglobin

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References

Powers AC, D’Alessio D. Endocrine Pancreas and Pharmacotherapy of Diabetes Mellitus and Hypoglycemia. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1259-61.
Nolte MS. Pancreatic hormones and antidiabetic drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 742-43.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1124-25.
Pioglitazone. Deerfield, Illinois; Takeda Pharmaceuticals America, Inc.; 1999 [revised Nov. 2013]. [Accessed 28 Jan. 2019] (online) Available from:
Pioglitazone hydrochloride [Product monograph]. Ontario, Canada: Takeda Canada Inc.; 2018. [Accessed 8 Oct. 2021] (online) Available from:
Actos [Summary of Product Characteristics]. County Wicklow, Ireland: Takeda Ireland Limited; 2010. [Accessed 8 October. 2021] (online) Available from:
Pioglitazone hydrochloride [Prescribing Information]. Baddi, Himachal Pradesh: Macleods Pharmaceutical Ltd.; 2022. [Accessed 05 Aug. 2023] (online) Available from:
Pioglitazone hydrochloride [Prescribing Information]. Baddi, Himachal Pradesh, India: Macleods Pharmaceutical Ltd.; 2022. [Accessed 05 Aug. 2023] (online) Available from:

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