Piosafe 30 Tablet

Prescription Required
SALT COMPOSITION
Storage
Store at room temperature (10-30°C)

Introduction

Piosafe 30 Tablet is a medicine used to treat type 2 diabetes mellitus in adults. It helps control blood sugar levels in people with diabetes. This helps to prevent serious complications of diabetes like kidney damage and blindness.

Piosafe 30 Tablet may be used by itself or along with other medicines. It may be taken with or without food. Take it regularly at the same time each day to get the most benefit. Your doctor will decide what dose is best for you and this may change from time to time according to how it is working.

Keep taking this medicine, even if you feel well or your blood sugar levels are controlled. If you stop it without consulting your doctor, your blood sugar levels could rise and put you at risk of kidney damage, blindness, nerve problems, and loss of limbs. Remember that it is only part of a treatment program that should also include a healthy diet, regular exercise, and weight reduction as advised by your doctor. Your lifestyle plays a big part in controlling diabetes.

The most common side effects of taking this medicine include weight gain, blurred vision, and numbness. Please consult your doctor if these bother you or persist for a longer duration.

You should not take it if you have type 1 diabetes mellitus, if you have diabetic ketoacidosis (high levels of acid in your blood), or if you have severe kidney or liver disease. Before taking this medicine, tell your doctor if you have ever had heart disease, thyroid disease, or some hormonal conditions. It may not be suitable. Pregnant or breastfeeding women should also consult their doctor before taking it. Your blood sugar levels should be checked regularly and your doctor may also advise blood tests to monitor your blood cell counts and liver function.

Uses of Piosafe Tablet

Benefits of Piosafe Tablet

In Type 2 diabetes mellitus

Piosafe 30 Tablet improves the body’s response to the hormone insulin responsible for regulating blood glucose (sugar) levels in our body. The insulin helps to lower your blood glucose levels and prevents them from rising after taking meals. You should keep taking it for as long as it is prescribed.
Lowering blood glucose levels is an essential part of managing diabetes. If you can control the level you will reduce the risk of getting any of the serious complications of diabetes such as kidney damage, eye damage, nerve problems, and loss of limbs. Taking this medicine regularly along with proper diet and exercise will help you live a normal, healthy life.

Side effects of Piosafe Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Piosafe

  • Weight gain
  • Blurred vision
  • Respiratory tract infection
  • Numbness
  • Bone fracture

How to use Piosafe Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Piosafe 30 Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Piosafe Tablet works

Piosafe 30 Tablet is an anti-diabetic medication. It works by increasing the body's sensitivity to insulin, a natural substance that helps control blood sugar levels.

Safety Advice

Alcohol
UNSAFE
It is unsafe to consume alcohol with Piosafe 30 Tablet.
Pregnancy
CONSULT YOUR DOCTOR
Piosafe 30 Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breastfeeding
SAFE IF PRESCRIBED
Piosafe 30 Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Monitor the breastfed baby’s blood sugar during treatment with Piosafe 30 Tablet
Driving
SAFE
Piosafe 30 Tablet does not usually affect your ability to drive.
Kidney
SAFE IF PRESCRIBED
Piosafe 30 Tablet is safe to use in patients with kidney disease. No dose adjustment of Piosafe 30 Tablet is recommended.
Use of Piosafe 30 Tablet is not recommended in patients undergoing dialysis.
Liver
CAUTION
Piosafe 30 Tablet should be used with caution in patients with liver disease. Dose adjustment of Piosafe 30 Tablet may be needed. Please consult your doctor.
Use of Piosafe 30 Tablet is not recommended in patients with severe liver disease.

What if you forget to take Piosafe Tablet?

If you miss a dose of Piosafe 30 Tablet, skip it and continue with your normal schedule. Do not double the dose.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Piosafe 30 Tablet
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Quick Tips

  • Piosafe 30 Tablet helps to control blood sugar level and avoid long-term complications.
  • Take it only as per dose and duration suggested by your doctor. 
  • You should continue to exercise regularly, eat a healthy diet, and take your other diabetes medicines along with Piosafe 30 Tablet.
  • Full effects may be visible after several weeks of starting Piosafe 30 Tablet. Keep taking it as prescribed by your doctor. 
  • Monitor your blood sugar level regularly while taking this medicine. 
  • Notify your doctor if you experience shortness of breath, heart problems, or any abnormal swelling.
  • Your doctor may monitor your liver function. Inform your doctor if you notice symptoms like abdominal pain, yellowing of eyes and loss of appetite. 

Fact Box

Chemical Class
Thiazolidinedione Derivative
Habit Forming
No
Therapeutic Class
ANTI DIABETIC
Action Class
Thiazolidinedione(PPAR gamma agonist)

Interaction with Drugs

Taking Piosafe with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Metstol, Tmp, Keno
LIFE-THREATENING
Brand(s): Amiur
SERIOUS
Brand(s): Densol, Catrisol, Betaforte
SERIOUS
Brand(s): Beza
SERIOUS

Patient Concerns

arrow
Diabetes mellitus type 2 ,thirst
Dr. Sanjay Bhatt
Physician
A person can control his or her sugar levels by doing regular exercise and walk or regular aerobic exercises at least 30 to 45 minutes per day.MEDICAL NUTRITIONAL THERAPY THAT IS TO MAINTAIN CALORIES INTAKE AS PER BMI .TAKE HELP OF DIABETIC EDUCATOR. VISIT YOUR DOCTOR AND FOLLOW ALL WHAT DOCTOR SUGGESTED.IN TIME ALL ROUTINE INVESTIGATIONS SHOULD BE DONE.you should not treat it as disease but a start of a healthy life.Uncontrolled sugar levels for long time leads to lower limb weakness which is neuropathy and which is followed by foot ulcers and other complications like kidney or heart problems .online prescription is not allowed without seeing pt.so contact doctor nearby for any change or dose adjustment or visit my clinic at gurgaon sector 52 RdCity snergy multi speciality clinic near SRS MARKET
Diabetes mellitus type 2 required only ayurvedic medicine
Dr. Sanjay Bhatt
Physician
Go for allopathic medicine
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FAQs

Q. Can Piosafe 30 Tablet cause weight gain?

Piosafe 30 Tablet commonly causes weight gain which may be dose-related. The reason for this weight gain could be fat accumulation. However, in heart failure patients it could be due to water retention in the body. Therefore, it is important to monitor weight in heart failure cases.

Q. Can Piosafe 30 Tablet cause heart failure?

Piosafe 30 Tablet can cause fluid retention which may aggravate or speed up heart failure. The doctor usually starts with the lowest available dose and increases the dose gradually while treating patients who have at least one risk factor for heart failure (previous heart attack, coronary artery disease, elderly). Heart failure is more common when Piosafe 30 Tablet is used with insulin.

Q. Can you take Piosafe 30 Tablet and metformin together?

Yes, Piosafe 30 Tablet can be used with metformin where sufficient blood sugar management was not possible with metformin alone. This combination of medicines can be used in adult patients with type 2 diabetes mellitus and overweight patients with poor blood sugar control.

Q. What time of day should you take Piosafe 30 Tablet?

It is usually prescribed once daily and can be taken at any time of the day but preferably at the same time each day. It can be taken with or without food. You should take Piosafe 30 Tablet exactly as prescribed by your doctor.

Q. How long do I need to take Piosafe 30 Tablet? Can I stop the medicine for some time?

Continue taking Piosafe 30 Tablet as long as your doctor recommends taking it. Treatment for diabetes mellitus is long-term so you may have to take it lifelong. However, if you have to stop it then consult with your doctor who will suggest an alternative. Do not stop taking it without consulting your doctor as it may cause blood sugar levels to rise, which could be harmful to you.

Q. Does Piosafe 30 Tablet affect liver?

Yes, Piosafe 30 Tablet may cause an increase in liver enzymes, and treatment with Piosafe 30 Tablet should be stopped if liver enzymes increase. Hence, levels of liver enzymes should be periodically checked while on treatment with this medicine. Piosafe 30 Tablet should not be prescribed to patients with liver disease.

Q. What kind of medicine is Piosafe 30 Tablet? Is it like metformin?

Piosafe 30 Tablet belongs to the thiazolidinediones class of anti-diabetic medicines. It helps control blood sugar levels by improving how your body uses a hormone called insulin. This is done by helping your cells become more sensitive to the insulin your body makes.

Q. Can Piosafe 30 Tablet cause bladder cancer?

Piosafe 30 Tablet may increase the risk of bladder cancer, though it is very rare. Immediately consult your doctor if you experience blood in your urine, pain when urinating or a sudden need to urinate, during treatment with this medicine. Piosafe 30 Tablet should not be used in patients with a prior history of bladder cancer or having bladder cancer.

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1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Powers AC, D’Alessio D. Endocrine Pancreas and Pharmacotherapy of Diabetes Mellitus and Hypoglycemia. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1259-61.
  2. Nolte MS. Pancreatic hormones and antidiabetic drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 742-43.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1124-25.
  4. Pioglitazone hydrochloride. Wooburn Green, High Wycombe: Takeda UK Ltd.; 2000 [revised 13 Sep. 2018]. [Accessed 28 Jan. 2019] (online) Available from:External Link
  5. Pioglitazone. Deerfield, Illinois; Takeda Pharmaceuticals America, Inc.; 1999 [revised Nov. 2013]. [Accessed 28 Jan. 2019] (online) Available from:External Link

Manufacturer/Marketer Address

Mercantile Chamber, 3rd Floor, 12, J.N. Heredia Marg, Ballard Estate, Mumbai – 400 001, India.
Country of Origin: India

Expires on or after: August, 2021

A licensed vendor partner from your nearest location will deliver Piosafe 30 Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
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