Author Details
Written By
MDS, BDS
Reviewed By
MD Pharmacology, MBBS
Last updated
21 Mar 2024 | 10:17 AM (IST)

We provide you with authentic, trustworthy and relevant information

Want to know more

Have issue with the content?

Report Problem

Pentasa 500mg Tablet PR

Prescription Required
SALT COMPOSITION
Salt Synonyms
Mesalamine
Storage
Store below 30°C
arrow
arrow

Product introduction

Pentasa 500mg Tablet PR is an anti-inflammatory medicine used to treat a type of bowel disease known as ulcerative colitis. It helps to reduce symptoms such as diarrhea, bleeding and stomach pain by reducing inflammation in the bowel.

Pentasa 500mg Tablet PR may also be used to treat another type of bowel disease known as Crohn’s ileocolitis. It should be taken with food. The dose will depend on what you are being treated for but take it exactly as your doctor prescribes. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen.

The most common side effects of this medicine include nausea, diarrhea, stomach pain, headache, itching, flatulence, and vomiting. If these symptoms bother you, do not go away, or get worse, let your doctor know. There may be ways of reducing or preventing them. Some people may get a severe allergic reaction that needs urgent medical attention. Contact your doctor immediately if you notice symptoms like swelling of the face, tongue, throat, or lips, unusual bleeding, bruising, rash, fever, sore throat, or excessive tiredness. 

Before taking it, tell your doctor if you have any kidney or liver problems or a blockage in your stomach. Your age may also be a factor in deciding whether this medicine is suitable. Pregnant or breastfeeding women should also consult their doctor before taking this medicine. Let your doctor know about all other medications you are taking as some may affect, or be affected by this medicine.

Uses of Pentasa Tablet PR

Benefits of Pentasa Tablet PR

In Ulcerative colitis

Ulcerative colitis is a disease of the large intestine (colon) and rectum in which the lining of the bowel becomes red and swollen. This can lead to bleeding, frequent diarrhea, and abdominal pain. Pentasa 500mg Tablet PR can relieve these symptoms and also help you to stay well by preventing them from coming back. There are many different brands and your doctor will decide which is most suitable for you. You need to take this medicine regularly to get the most out of it and you should drink plenty of fluids while taking it to make sure you stay hydrated.

In Crohn’s disease

Crohn’s disease is a chronic (long-term) inflammatory disease of the intestines. The most common symptoms are diarrhea and pain in your abdomen. Pentasa 500mg Tablet PR helps reduce the inflammation, relieve the symptoms, and prevent them from coming back.

Side effects of Pentasa Tablet PR

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Pentasa

  • Stomach pain/epigastric pain
  • Flatulence
  • Headache
  • Vomiting
  • Diarrhea
  • Nausea
  • Abdominal pain
  • Rash

How to use Pentasa Tablet PR

Use it as advised by your doctor or check the label for directions before use. Pentasa 500mg Tablet PR may be taken with or without food, but it is better to take it at a fixed time.

How Pentasa Tablet PR works

Pentasa 500mg Tablet PR is an aminosalicylate. It works by suppressing the production of chemical messengers (prostaglandins) that cause inflammation (swelling) in the intestines. This reduces ulceration, bleeding and stomach pain, and prevents future flare-ups of the disease.

Safety advice

Alcohol
CAUTION
Caution is advised when consuming alcohol with Pentasa 500mg Tablet PR. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Pentasa 500mg Tablet PR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Pentasa 500mg Tablet PR is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
If you are taking Pentasa 500mg Tablet PR, monitor the baby for diarrhea.
Driving
SAFE
Pentasa 500mg Tablet PR does not usually affect your ability to drive.
Kidney
CAUTION
Pentasa 500mg Tablet PR should be used with caution in patients with kidney disease. Dose adjustment of Pentasa 500mg Tablet PR may be needed. Please consult your doctor.
Use of Pentasa 500mg Tablet PR is not recommended in patients with severe kidney disease.
Liver
CAUTION
Pentasa 500mg Tablet PR should be used with caution in patients with liver disease. Dose adjustment of Pentasa 500mg Tablet PR may be needed. Please consult your doctor.

What if you forget to take Pentasa Tablet PR?

If you miss a dose of Pentasa 500mg Tablet PR, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.\n

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Pentasa 500mg Tablet PR
₹26.8/Tablet PR
Mesacol CR 500mg Tablet
Sun Pharmaceutical Industries Ltd
₹22.4/tablet pr
16% cheaper

Quick tips

  • You have been prescribed Pentasa 500mg Tablet PR for treating and lowering the symptoms of mild inflammatory bowel disease such as ulcerative colitis.
  • Your doctor may monitor your kidney and liver functions before you start treatment with this medicine and regularly thereafter. Inform your doctor if you have severely decreased kidney or liver function.
  • Do not take Pentasa 500mg Tablet PR if you are allergic to aspirin or if you have blood disorders.
  • Do not stop taking the medication suddenly without talking to your doctor.

Fact Box

Chemical Class
Aminosalicylic Acids Derivative
Habit Forming
No
Therapeutic Class
GASTRO INTESTINAL
Action Class
5- Aminosalicylic acid (5-ASA)

Interaction with drugs

Taking Pentasa with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Thioprinz, Lazorin, Azarid
Serious
Brand(s): Purinetone, 6-MP, Captomer
Serious

Patient concerns

arrow
Suffering from ultratics colitis i have done colonoscopy test 04 months back From 05 months how many months I have to take medicines is it cure completely
Dr. Kunal Parasar
Surgical Gastroenterology
Ulcerative colitis is a lifelong disease with remission and exacerbations. Durations of remission cant b predicted all d time
Hi, I was diagnosed for Ulcerative Colitis in 2009. I was administered with Mesacol , I was back to normal. In past 1 month , after having food lunch or dinner I feel uneasy such as indigestion, having to force for motions next day. Sometimes Iam unable to pass motions. I feel tired also. Pls suggest.
Dr. Kunal Parasar
Surgical Gastroenterology
Ulcerative colitis is a lifong disease q with remission and exacerbation . U should b under constant follow up of ur gastroenterologist
arrow

User feedback


FAQs

Q. My symptoms have improved can I stop taking Pentasa 500mg Tablet PR?

Continue to take Pentasa 500mg Tablet PR as advised by the doctor, even if you feel better at the beginning of your treatment. Do not stop taking Pentasa 500mg Tablet PR without consulting your doctor.

Q. Can I drink alcohol while taking Pentasa 500mg Tablet PR?

You should avoid alcohol if you have ulcerative colitis, as alcohol will irritate your stomach and intestine which will worsen your condition. Although alcohol does not interfere with the working of Pentasa 500mg Tablet PR, you should consult your doctor before taking alcohol.

Q. Does Pentasa 500mg Tablet PR cause joint pain?

Yes, Pentasa 500mg Tablet PR may cause joint pain. If the pain continues and bothers you inform your doctor.

Q. When is the best time to take Pentasa 500mg Tablet PR?

Take Pentasa 500mg Tablet PR exactly as directed by your doctor.

Related ayurvedic ingredients

Want to share the information?

Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Mesalazine/Mesalamine. Milan, Italy: Cosmo S.p.A.; 1987 [revised date]. [Accessed on 28 Mar. 2018] (online) Available from:External Link
  2. Mesalamine. Weiterstadt Germany: Warner Chilcott Deutschland GmbH; [revised May 2010]. [Accessed 28 Mar. 2019] (online) Available from:External Link
  3. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Mesalamine. [Updated 2019 Apr 1]. [Accessed 20 Feb. 2020] (online) Available from:External Link
  4. Central Drugs Standard Control Organisation (CDSCO). [Accessed 28 Mar. 2019] (online) Available from:External Link
  5. National Health Service. Mesalazine. [Last Reviewed: 19 Jul. 2021]. [Accessed 11 Jul. 2023]. (online) Available from:External Link
  6. Mesalazine [Package Insert]. Saint-Prex, Switzerland: Ferring International Center SA. [Accessed 11 Jul. 2023]. (online) Available from:External Link

Marketer details

Name: Ferring Pharmaceuticals
Address: K-28/1, ADDITIONAL MIDC , ANAND NAGAR , AMBERNATH - 421506 , INDIA
Country of origin: India
Expires on or after: January, 2025

A licensed vendor partner from your nearest location will deliver Pentasa 500mg Tablet PR. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

227.8281.8Get 19% OFF
217.08+ free shipping withCare Plan Logo
Inclusive of all taxes
This offer price is valid on your first order above ₹999. Apply coupon TATA1MGNEW on the cart. Max. coupon discount is ₹310. T&C apply.
10.0 Tablet pr in 1 strip
Add to cart
Cash on delivery available
Get it delivered by 10pm, Tomorrow
Delivering to:
110020, New DelhiDown Arrow Icon

Additional offers

Tata Pay Later: Get up to Rs. 500 Neu coins for every transaction on Tata 1mg above Rs. 100 from 1st to 5th May using Tata Pay Later.
Show more show_more

INDIA’S LARGEST HEALTHCARE PLATFORM

260m+
Visitors
31m+
Orders Delivered
1800+
Cities
Get the link to download App
Reliable

All products displayed on Tata 1mg are procured from verified and licensed pharmacies. All labs listed on the platform are accredited

Secure

Tata 1mg uses Secure Sockets Layer (SSL) 128-bit encryption and is Payment Card Industry Data Security Standard (PCI DSS) compliant

Affordable

Find affordable medicine substitutes, save up to 50% on health products, up to 80% off on lab tests and free doctor consultations.

LegitScript approved
India's only LegitScript and ISO/ IEC 27001 certified online healthcare platform

Know more about Tata 1mgdownArrow

Access medical and health information

Tata 1mg provides you with medical information which is curated, written and verified by experts, accurate and trustworthy. Our experts create high-quality content about medicines, diseases, lab investigations, Over-The-Counter (OTC) health products, Ayurvedic herbs/ingredients, and alternative remedies.

Order medicines online

Get free medicine home delivery in over 1800 cities across India. You can also order Ayurvedic, Homeopathic and other Over-The-Counter (OTC) health products. Your safety is our top priority. All products displayed on Tata 1mg are procured from verified and licensed pharmacies.

Book lab tests

Book any lab tests and preventive health packages from certified labs and get tested from the comfort of your home. Enjoy free home sample collection, view reports online and consult a doctor online for free.

Consult a doctor online

Got a health query? Consult doctors online from the comfort of your home for free. Chat privately with our registered medical specialists to connect directly with verified doctors. Your privacy is guaranteed.