Pamidria 90mg Injection
Prescription Required
Product introduction
Pamidria 90mg Injection is used to treat high levels of a mineral called calcium in people who have cancer. It is also used to treat or prevent weakening of the bones. Using this medicine can reduce your risk of breaking bones.
Pamidria 90mg Injection is given by a doctor or nurse. You will not need to do this yourself. How much you are given, and how often, will be decided by your doctor. It may just be a single injection but if you are being treated for bone problems caused by the spread of cancer you may need regular injections. Your doctor will ask you to drink plenty of water before the injection, to avoid getting dehydrated. It may take several days to get the full benefit of this drug. Pamidria 90mg Injection is only part of a program of treatment that may also include changes to your diet and taking calcium and vitamin supplements.
The most common side effects include headache, back pain, muscle pain, indigestion, diarrhea, and heartburn. These are usually mild and will disappear after a short time. If they do not go away, tell your doctor. Pamidria 90mg Injection can cause serious kidney problems, especially if you are dehydrated, if you take diuretic medicine (water pills), or if you already have kidney disease. It can also cause low levels of calcium in the blood and pain in the mouth or jaw. These are serious side effects and need urgent medical attention. Tell your doctor straight away.
You should not be given this medicine if you are breastfeeding. Before taking it, tell your doctor if you have kidney problems or low calcium levels. Also, let your doctor know what other drugs you are taking. Some of them may affect, or be affected by, this injection, especially medicines used to treat severe infections and medicines used to treat cancer and osteoporosis. You may need frequent medical tests to check your kidney function and mineral levels. Avoid smoking or try to quit as smoking can reduce your bone mineral density, making fractures more likely. Drinking large amounts of alcohol can also cause bone loss and should be avoided.
Pamidria 90mg Injection is given by a doctor or nurse. You will not need to do this yourself. How much you are given, and how often, will be decided by your doctor. It may just be a single injection but if you are being treated for bone problems caused by the spread of cancer you may need regular injections. Your doctor will ask you to drink plenty of water before the injection, to avoid getting dehydrated. It may take several days to get the full benefit of this drug. Pamidria 90mg Injection is only part of a program of treatment that may also include changes to your diet and taking calcium and vitamin supplements.
The most common side effects include headache, back pain, muscle pain, indigestion, diarrhea, and heartburn. These are usually mild and will disappear after a short time. If they do not go away, tell your doctor. Pamidria 90mg Injection can cause serious kidney problems, especially if you are dehydrated, if you take diuretic medicine (water pills), or if you already have kidney disease. It can also cause low levels of calcium in the blood and pain in the mouth or jaw. These are serious side effects and need urgent medical attention. Tell your doctor straight away.
You should not be given this medicine if you are breastfeeding. Before taking it, tell your doctor if you have kidney problems or low calcium levels. Also, let your doctor know what other drugs you are taking. Some of them may affect, or be affected by, this injection, especially medicines used to treat severe infections and medicines used to treat cancer and osteoporosis. You may need frequent medical tests to check your kidney function and mineral levels. Avoid smoking or try to quit as smoking can reduce your bone mineral density, making fractures more likely. Drinking large amounts of alcohol can also cause bone loss and should be avoided.
Uses of Pamidria Injection
- Osteoporosis
- Hypercalcemia
Benefits of Pamidria Injection
In Hypercalcemia
Calcium is a mineral found in different places in your body and has many functions including bone growth. Most of your calcium should be in your bones. When you have more calcium in your blood than normal it is called hypercalcaemia (high blood calcium levels). It is a serious condition and affects a large number of people with cancer. Pamidria 90mg Injection is a type of medicine called a bisphosphonate. It reduces the amount of calcium in your blood by slowing down the rate at which bone is broken down in your body. This medicine is normally only given once by injection to treat hypercalcaemia, but you may need additional doses. Make sure you attend all appointments with your doctor.
Being immobile makes hypercalcaemia worse. Whenever possible you should take regular exercise, especially weight-bearing exercise. Do not take calcium or vitamin D3 supplements and try to decrease your intake of these in your diet.
Being immobile makes hypercalcaemia worse. Whenever possible you should take regular exercise, especially weight-bearing exercise. Do not take calcium or vitamin D3 supplements and try to decrease your intake of these in your diet.
Side effects of Pamidria Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Pamidria
- Headache
- Back pain
- Musculoskeletal (bone, muscle or joint) pain
- Heartburn
- Diarrhea
- Indigestion
How to use Pamidria Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Pamidria Injection works
Pamidria 90mg Injection is a bisphosphonate. It acts by suppressing the activity of osteoclasts, cells that cause the destruction of bone, thereby strengthening the bones and minimizing the risk of fractures.
Safety advice
Alcohol
SAFE
Consuming alcohol with Pamidria 90mg Injection does not cause any harmful side effects.
Pregnancy
CONSULT YOUR DOCTOR
Pamidria 90mg Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding
CAUTION
Pamidria 90mg Injection should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.
If you are taking Pamidria 90mg Injection during breastfeeding, monitor the baby's blood calcium levels during the first two months.
If you are taking Pamidria 90mg Injection during breastfeeding, monitor the baby's blood calcium levels during the first two months.
Driving
UNSAFE
Pamidria 90mg Injection may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
CAUTION
Pamidria 90mg Injection should be used with caution in patients with severe kidney disease. Dose adjustment of Pamidria 90mg Injection may be needed. Please consult your doctor.
Liver
CAUTION
Pamidria 90mg Injection should be used with caution in patients with severe liver disease. Dose adjustment of Pamidria 90mg Injection may be needed. Please consult your doctor.
Limited information is available on the use of Pamidria 90mg Injection in these patients. No dose adjustment is recommended in patients with mild to moderate liver disease.
Limited information is available on the use of Pamidria 90mg Injection in these patients. No dose adjustment is recommended in patients with mild to moderate liver disease.
What if you forget to take Pamidria Injection?
If you miss a dose of Pamidria 90mg Injection, skip it and continue with your normal schedule. Do not double the dose.\n
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Quick tips
- It is given by injection into a vein, usually over at least 15 minutes or as directed by your doctor.
- Drink plenty of fluids to prevent dehydration and kidney damage.
- It can lower the level of calcium in the blood. Take calcium and vitamin D supplements as suggested by your doctor.
- You may develop fever or flu like symptoms, such as chills, tiredness and weakness. These are usually temporary and should go away after a few days. You may take a pain reliever/fever reducer to prevent or treat these symptoms.
- It may cause a rare condition called osteonecrosis of the jaw. Have regular dental check-ups and inform your doctor if you develop sudden pain in your jaw.
- Your doctor will monitor your response to Pamidria 90mg Injection by testing your bone mineral density (BMD). This is usually done every 1-3 years.
- Do not take it if you are pregnant or breastfeeding.
- Your doctor has prescribed Pamidria 90mg Injection to make your bones stronger and lower the risk of fractures.
- Take it in the morning at least 30 minutes before eating or drinking anything.
- Maintain an upright posture for 30 minutes after taking the medication so the medicine does not irritate your food pipe.
- It may cause the amount of calcium in your blood to fall. Take calcium-rich food in your diet and have regular blood tests to monitor the level of calcium in your blood.
- It is important to look after your mouth and teeth while you are taking this medicine. Have regular dental check-ups and inform your dentist about taking Pamidria 90mg Injection.
Fact Box
Chemical Class
Bisphosphonate Derivative
Habit Forming
No
Therapeutic Class
PAIN ANALGESICS
Action Class
Bone Resorption Inhibitors- Bisphosphonates
Interaction with drugs
Taking Pamidria with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Concurrent use may cause a serious drop in blood calcium levels.
Your doctor may monitor your calcium and magnesium levels along with your overall treatment and adjust the doses a
Concurrent use may cause a serious drop in blood calcium levels.
Your doctor may monitor your calcium and magnesium levels along with your overall treatment and adjust the doses a
Concurrent use may cause a serious drop in blood calcium levels.
Your doctor may monitor your calcium and magnesium levels along with your overall treatment and adjust the doses a
Concurrent use may cause a serious drop in blood calcium levels.
Your doctor may monitor your calcium and magnesium levels along with your overall treatment and adjust the doses a
Concurrent use may cause a serious drop in blood calcium levels.
Your doctor may monitor your calcium and magnesium levels along with your overall treatment and adjust the doses a
Patient concerns
FAQs
What does Pamidria 90mg Injection do?
Pamidria 90mg Injection helps in preventing breakdown of the bones. Bone is continuously being broken down and regenerated by special kinds of bone cells by a process called remodelling or turnover. However, conditions like bone stress and bone marrow edema may create pain and imbalance in this daily turnover. Pamidria 90mg Injection acts in the areas with increased bone turnover, decreases this process of breakdown and thereby reduces the pain and discomfort associated with it.
How is Pamidria 90mg Injection administered?
Pamidria 90mg Injection should be administered under the supervision of a doctor or a trained healthcare professional and should not be self-administered. It is given as a 1-2 hour infusion by a drip into a vein in your arm. The dose will depend on the condition you are being treated for and will be decided by your doctor. Follow your doctor’s instructions carefully to get maximum benefit from Pamidria 90mg Injection.
How often will I be given Pamidria 90mg Injection?
Your dose of Pamidria 90mg Injection will be decided by your doctor depending on your condition. Usually, an individual requires 1-3 doses of Pamidria 90mg Injection.However, the exact dose and its frequency will depend on your illness and how well you respond to the treatment.
Is Pamidria 90mg Injection safe in pregnancy or breastfeeding?
No, Pamidria 90mg Injection may not be safe in pregnancy or breastfeeding. Although Pamidria 90mg Injection does not affect the fertility of women or the sperm count in males, it is best to consult your doctor before taking Pamidria 90mg Injection. In general, avoid Pamidria 90mg Injection if you are pregnant, planning to get pregnant or breastfeeding to avoid any harmful effects on the baby. There is not enough data available to know the exact effect of Pamidria 90mg Injection on the unborn baby or via breast milk. Also, women who are taking Pamidria 90mg Injection are advised to avoid pregnancy after 6 months of completing treatment with Pamidria 90mg Injection.. This is because traces of Pamidria 90mg Injection stays in the bones for long periods of time and may be released during this time which can cause harm to the baby.
Does Pamidria 90mg Injection cause hair loss?
Yes, Pamidria 90mg Injection can cause hair loss, but this is not a common side effect. If you experience hair loss while taking this medication immediately report to your doctor and follow the advice given.
Is Pamidria 90mg Injection safe?
Pamidria 90mg Injection is safe if used in the dose and duration advised by your doctor. Take it exactly as directed and do not skip any dose. Follow your doctor's instructions carefully and let your doctor know if any of the side effects bother you.
What other lifestyle changes should I make?
To get maximum benefit from Pamidria 90mg Injection, there are certain lifestyle changes that you must adhere to. Include some calcium or Vitamin D rich foods for bone strength. Try to spend more time in sunlight to get natural vitamin D. Quit smoking and reduce alcohol consumption as they may harm your bones. You can take up an exercise regime such as walking and low-impact aerobics as they are good for your bones. Similarly, you can try strength-training exercises where you use your own body weight which in turn improve bone health.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1050-52.
- Pamidronate. Hurley, Maidenhead: Hospira UK Ltd.; 2009 [revised Jun. 2016]. [Accessed 02 Apr. 2019] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 02 Apr. 2019] (online) Available from:
Marketer details
Name: Cipla Ltd
Address: Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013
Country of origin: India
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