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Pamidronate

Information

Uses

Pamidronate is used in the treatment of post menopausal osteoporosis (porous bones), osteoporosis in men (porous bones) and steroid induced osteoporosis (porous bones)

How it works

Pamidronate inhibits the activity of osteoclasts, cells that causes loss of bone.

Common side effects

Headache, Back pain, Joint pain, Indigestion, Shortness of breath, Gastro-esophageal reflux disease, Abdominal pain, Muscle pain, Fatigue, Nausea, Fever, Constipation, Diarrhoea, Anemia, Musculoskeletal pain

Available Medicine

Expert advice

  • Consult your doctor if you have any of the following medical conditions: heart problems, liver/kidney/thyroid disorders; low levels of platelets and red blood cells; calcium or vitamin D deficiency; teeth or jaw problems or flu like conditions.
  • Consult your doctor if you are taking medicines such as calcitonin, thalidomide, other bisphosphonate drugs, or medicines used to treat kidney problems.
  • Keep yourself hydrated while being treated with pamidronate.
  • Be careful with your dental hygiene; avoid dental extraction or other invasive dental procedures while on pamidronate therapy.
  • Pamidronate may cause bone loss in the jaw (osteonecrosis of the jaw leading to jaw pain, swelling, numbness, loose teeth, gum infection, or slow healing after injury or surgery involving the gums). Stop using the medicine if you develop any such reaction.
  • Do not drive or operate heavy machinery as you can feel dizzy after taking this drug.

Frequently asked questions

Pamidronate

Q. How does pamidronate work?
Pamidronate works by decreasing the level of calcium released into the blood by bones, thereby preventing calcium excess in the body

Q. Is pamidronate safe?
Yes. Pamidronate is safe if used at prescribed doses for the prescribed duration as advised by your doctor. In case of any side-effects, please consult your doctor.


Content on this page was last updated on 15 January, 2017, by Dr. Varun Gupta (MD Pharmacology)