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06 Nov 2020 | 04:00 AM (IST)
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Pamidria 30mg Injection

Prescription Required
Manufacturer
SALT COMPOSITION
Storage
Store at room temperature (10-30°C)

Introduction

Pamidria 30mg Injection is used to treat high levels of a mineral called calcium in people who have cancer. It is also used to treat or prevent weakening of the bones. Using this medicine can reduce your risk of breaking bones.

Pamidria 30mg Injection is given by a doctor or nurse. You will not need to do this yourself. How much you are given, and how often, will be decided by your doctor. It may just be a single injection but if you are being treated for bone problems caused by the spread of cancer you may need regular injections. Your doctor will ask you to drink plenty of water before the injection, to avoid getting dehydrated. It may take several days to get the full benefit of this drug. Pamidria 30mg Injection is only part of a program of treatment that may also include changes to your diet and taking calcium and vitamin supplements.

The most common side effects include headache, back pain, muscle pain, indigestion, diarrhea, and heartburn. These are usually mild and will disappear after a short time. If they do not go away, tell your doctor. Pamidria 30mg Injection can cause serious kidney problems, especially if you are dehydrated, if you take diuretic medicine (water pills), or if you already have kidney disease. It can also cause low levels of calcium in the blood and pain in the mouth or jaw. These are serious side effects and need urgent medical attention. Tell your doctor straight away.

You should not be given this medicine if you are breastfeeding. Before taking it, tell your doctor if you have kidney problems or low calcium levels. Also, let your doctor know what other drugs you are taking. Some of them may affect, or be affected by, this injection, especially medicines used to treat severe infections and medicines used to treat cancer and osteoporosis. You may need frequent medical tests to check your kidney function and mineral levels. Avoid smoking or try to quit as smoking can reduce your bone mineral density, making fractures more likely. Drinking large amounts of alcohol can also cause bone loss and should be avoided.

Uses of Pamidria Injection

Benefits of Pamidria Injection

In Osteoporosis

Osteoporosis is a common condition that weakens bones, making them fragile and more likely to break. It often occurs in women after menopause. This condition can be treated with bone-strengthening medicines. Pamidria 30mg Injection is a type of medicine called a bisphosphonate. It slows down the rate at which bone is broken down in your body. This maintains bone density and reduces your risk of breaking a bone. The injection is usually given once every year to treat osteoporosis and every two years to prevent it.

You can help improve the strength of you bones by doing regular exercise (especially weight-bearing exercise), eating healthy foods containing calcium and Vitamin D and reducing your consumption of alcohol and tobacco. Supplements of calcium and Vitamin D3 are also effective.

In Hypercalcemia

Calcium is a mineral found in different places in your body and has many functions including bone growth. Most of your calcium should be in your bones. When you have more calcium in your blood than normal it is called hypercalcaemia (high blood calcium levels). It is a serious condition and affects a large number of people with cancer. Pamidria 30mg Injection is a type of medicine called a bisphosphonate. It reduces the amount of calcium in your blood by slowing down the rate at which bone is broken down in your body. This medicine is normally only given once by injection to treat hypercalcaemia, but you may need additional doses. Make sure you attend all appointments with your doctor.

Being immobile makes hypercalcaemia worse. Whenever possible you should take regular exercise, especially weight-bearing exercise. Do not take calcium or vitamin D3 supplements and try to decrease your intake of these in your diet.

Side effects of Pamidria Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Pamidria

  • Headache
  • Back pain
  • Musculoskeletal (bone, muscle or joint) pain
  • Heartburn
  • Diarrhea
  • Indigestion

How to use Pamidria Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Pamidria Injection works

Pamidria 30mg Injection is a bisphosphonate. It acts by suppressing the activity of osteoclasts, cells that cause the destruction of bone, thereby strengthening the bones and minimizing the risk of fractures.

Safety Advice

Alcohol
SAFE
Consuming alcohol with Pamidria 30mg Injection does not cause any harmful side effects.
Pregnancy
CONSULT YOUR DOCTOR
Pamidria 30mg Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breastfeeding
SAFE IF PRESCRIBED
Pamidria 30mg Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
If you are taking Pamidria 30mg Injection during breastfeeding, monitor baby's blood calcium levels during the first two months.
Driving
UNSAFE
Pamidria 30mg Injection may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
CAUTION
Pamidria 30mg Injection should be used with caution in patients with severe kidney disease. Dose adjustment of Pamidria 30mg Injection may be needed. Please consult your doctor.
Liver
CAUTION
Pamidria 30mg Injection should be used with caution in patients with severe liver disease. Dose adjustment of Pamidria 30mg Injection may be needed. Please consult your doctor.
Limited information is available on the use of Pamidria 30mg Injection in these patients. No dose adjustment is recommended in patients with mild to moderate liver disease.

What if you forget to take Pamidria Injection?

If you miss a dose of Pamidria 30mg Injection, skip it and continue with your normal schedule. Do not double the dose.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Pamidria 30mg Injection
₹230.6/ml of Injection
Pamidro 30mg Injection
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Biodronate 30mg Injection
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₹1445.5/ml of Injection
527% costlier
Aredronet 30mg Injection
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₹1830.4/Injection
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Bonapam 30mg Injection
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₹2306/Injection
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Aredia 30mg Injection
Novartis India Ltd
₹4112/Injection
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Quick Tips

  • It is given by injection into a vein, usually over at least 15 minutes or as directed by your doctor.
  • Drink plenty of fluids to prevent dehydration and kidney damage.
  • It can lower the level of calcium in the blood. Take calcium and vitamin D supplements as suggested by your doctor.
  • You may develop fever or flu like symptoms, such as chills, tiredness and weakness. These are usually temporary and should go away after a few days. You may take a pain reliever/fever reducer to prevent or treat these symptoms.
  • It may cause a rare condition called osteonecrosis of the jaw. Have regular dental check-ups and inform your doctor if you develop sudden pain in your jaw.
  • Your doctor will monitor your response to Pamidria 30mg Injection by testing your bone mineral density (BMD). This is usually done every 1-3 years.
  • Do not take it if you are pregnant or breastfeeding.

Fact Box

Chemical Class
Bisphosphonate Derivative
Habit Forming
No
Therapeutic Class
PAIN ANALGESICS

Interaction with Drugs

Taking Pamidria with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Mikasun, Vizocin, Amricin
SERIOUS
Brand(s): Ciprix, Capreo, Capreotec
SERIOUS
Brand(s): Begenta, Indogenta, Spagen
SERIOUS
Brand(s): Neokanyn
SERIOUS

Patient Concerns

arrow
Teriparatide is this injection advisable?
Dr. Akshat Goel
Orthopaedics
Yes, it's good in Osteoporosis
I am suffering osteoporosis since 9 years. I came to know that without knee joint replacement, have another option I.e halonix injection treatment. So please can u give about injections treatment in detail
Dr. Akshat Goel
Orthopaedics
It is a newer option with good results in early stages of Osteoarthritis
arrow
Do you have any questions related to Pamidria 30mg Injection ?

FAQs

Q. What does Pamidria 30mg Injection do?

Pamidria 30mg Injection helps in preventing breakdown of the bones. Bone is continuously being broken down and regenerated by special kinds of bone cells by a process called remodelling or turnover. However, conditions like bone stress and bone marrow edema may create pain and imbalance in this daily turnover. Pamidria 30mg Injection acts in the areas with increased bone turnover, decreases this process of breakdown and thereby reduces the pain and discomfort associated with it.

Q. How is Pamidria 30mg Injection administered?

Pamidria 30mg Injection should be administered under the supervision of a doctor or a trained healthcare professional and should not be self-administered. It is given as a 1-2 hour infusion by a drip into a vein in your arm. The dose will depend on the condition you are being treated for and will be decided by your doctor. Follow your doctor’s instructions carefully to get maximum benefit from Pamidria 30mg Injection.

Q. How often will I be given Pamidria 30mg Injection?

Your dose of Pamidria 30mg Injection will be decided by your doctor depending on your condition. Usually, an individual requires 1-3 doses of Pamidria 30mg Injection.However, the exact dose and its frequency will depend on your illness and how well you respond to the treatment.

Q. Is Pamidria 30mg Injection safe in pregnancy or breastfeeding?

No, Pamidria 30mg Injection may not be safe in pregnancy or breastfeeding. Although Pamidria 30mg Injection does not affect the fertility of women or the sperm count in males, it is best to consult your doctor before taking Pamidria 30mg Injection. In general, avoid Pamidria 30mg Injection if you are pregnant, planning to get pregnant or breastfeeding to avoid any harmful effects on the baby. There is not enough data available to know the exact effect of Pamidria 30mg Injection on the unborn baby or via breast milk. Also, women who are taking Pamidria 30mg Injection are advised to avoid pregnancy after 6 months of completing treatment with Pamidria 30mg Injection.. This is because traces of Pamidria 30mg Injection stays in the bones for long periods of time and may be released during this time which can cause harm to the baby.

Q. Does Pamidria 30mg Injection cause hair loss?

Yes, Pamidria 30mg Injection can cause hair loss, but this is not a common side effect. If you experience hair loss while taking this medication immediately report to your doctor and follow the advice given.

Q. Is Pamidria 30mg Injection safe?

Pamidria 30mg Injection is safe if used in the dose and duration advised by your doctor. Take it exactly as directed and do not skip any dose. Follow your doctor's instructions carefully and let your doctor know if any of the side effects bother you.

Q. What other lifestyle changes should I make?

To get maximum benefit from Pamidria 30mg Injection, there are certain lifestyle changes that you must adhere to. Include some calcium or Vitamin D rich foods for bone strength. Try to spend more time in sunlight to get natural vitamin D. Quit smoking and reduce alcohol consumption as they may harm your bones. You can take up an exercise regime such as walking and low-impact aerobics as they are good for your bones. Similarly, you can try strength-training exercises where you use your own body weight which in turn improve bone health.

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1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1050-52.
  2. Pamidronate. Hurley, Maidenhead: Hospira UK Ltd.; 2009 [revised Jun. 2016]. [Accessed 02 Apr. 2019] (online) Available from:External Link
  3. Central Drugs Standard Control Organisation (CDSCO). [Accessed 02 Apr. 2019] (online) Available from:External Link

Manufacturer/Marketer Address

Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013
Best Price
₹1960.1
MRP2306  Get 15% OFF
Inclusive of all taxes
10 ml in 1 vial
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