Onglyza 5mg Tablet

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Astra Zeneca

Composition for Onglyza 5mg Tablet

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Primarily used for

Potentiallyunsafewith
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Alcohol
1210
₹43.21/Tablet
28 tablets in 1 box
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Medicine Overview of Onglyza Tablet

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Uses of Onglyza Tablet

Onglyza 5mg Tablet is used in the treatment of type 2 diabetes
It is used in addition to diet and exercise to improve blood sugar control in adults with type 2 diabetes.
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Side effects of Onglyza Tablet

Common

Headache, Upper respiratory tract infection, Hypoglycaemia (low blood sugar level) in combination with insulin or sulphonylurea, Nasopharyngitis.

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How to use Onglyza Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. It can be taken with or without food, but it is better to take Onglyza 5mg Tablet at a fixed time.

How Onglyza Tablet works

Onglyza 5mg tablet is an anti-diabetic medication. It works by increasing the amount of insulin produced by the pancreas after meals when blood sugar is high.

In Depth Information on Onglyza Tablet

Expert advice for Onglyza Tablet

  • Onglyza can be taken with or without food.
  • Chances of weight gain and low blood sugar are lesser as compared to other diabetes medicines.
  • Get your blood sugar monitored regularly.
  • Inform your doctor immediately if you have severe stomach pain, nausea, and/or vomiting. These could be symptoms of pancreatitis.
  • Inform your doctor immediately if you have severe joint pain.
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Warnings
Special precautions for Onglyza 5mg Tablet
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Alcohol
CAUTION
Taking alcohol together with saxagliptin may affect blood glucose levels in patients with diabetes.
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Pregnancy
PROBABLY SAFE
Onglyza 5mg Tablet is probably safe to use during pregnancy.

Animal studies have shown low or no adverse effect on the foetus, however, there are limited human studies. Please consult your doctor.
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Lactation
Onglyza 5mg Tablet is probably safe to use during lactation.
Limited human data suggests that the drug does not represent a significant risk to the baby.
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Driving
Your ability to drive may be affected if your blood sugar is
low or high. If this happens, do not drive.
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Kidney
CAUTION
Onglyza 5mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Onglyza 5mg Tablet may be needed. Please consult your doctor.

Regular monitoring of kidney function tests is recommended for dose adjustment.
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Liver
Onglyza 5mg Tablet should be used with caution in patients with severe liver disease. Dose adjustment of Onglyza 5mg Tablet may be needed. Please consult your doctor.

No dose adjustment is recommended for patients with mild to moderate liver disease.
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Severely interacts with other drugs like
Decmax 4mg Tablet, Decamycin 4mg Injection, Pericort 4mg Tablet, Depo Medrol 40mg/ml Injection

Missed Dosageuses

If you miss a dose of Saxagliptin, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Patient Concerns

Frequently asked questions for Onglyza 5mg Tablet

Frequently asked questions for Saxagliptin

No, Onglyza neither causes weight loss nor weight gain. It is weight neutral. However, weight gain can be seen when Onglyza is used with other antidiabetic medicines like thiazolidinediones, sulfonylureas or insulin.
Onglyza belongs to the group of drugs called incretins which have been associated with pancreatic cancer in some clinical studies. However, a definite evidence that they cause cancer is missing, so, it is advisable to talk to your doctor regarding the same.
Q. Can I use Onglyza with pioglitazone?
Yes, Onglyza can be used with pioglitazone. A combined use of the two medicines would be more effective in controlling blood sugar levels than either medicine alone. No drug-drug interactions or any change in side effect profile has been reported compared to when they are used alone.
Onglyza is seen to be efficacious in the management of parkinsonism in some animal research studies only and is not advised for the management of parkinsonism in humans currently.
Q. What is the difference between Onglyza and vildagliptin?
Vildagliptin and Onglyza belong to the same class of anti-diabetic drugs. However, Vildagliptin is seen to be more effective in controlling blood sugar levels with fewer fluctuations compared to Onglyza. But Vildagliptin is to be taken twice a day while Onglyza is taken once a day.
Q. How beneficial is it to use a combination of Onglyza and gliclazide?
Yes, Onglyza and gliclazide can be taken together as they can help in better control of blood sugar levels. However, the risk of low blood sugar levels (hypoglycemia) can increase. Consult your doctor as a dose adjustment of the two may be needed.
Onglyza when taken with insulin can help in lowering the insulin dose and decrease the risk of hypoglycemia (low blood sugar levels). Consult your doctor as a dose adjustment of the two may be needed.
Q. Would the results be better if I take Onglyza with metformin?
Yes, metformin taken along with Onglyza can help in better reduction of blood sugar levels compared to either drug taken alone. Moreover, fixed dose combinations of Onglyza with metformin are available.
Yes, the use of Onglyza is contraindicated in some conditions like a history of allergy to Onglyza, any ingredients of this drug or to any other drug of the same class. Onglyza should also be avoided in patients with a history of pancreatitis.
Q. Can I use Onglyza with dapagliflozin?
Yes, Onglyza can be used along with dapagliflozin. Both are antidiabetic drugs and can achieve better reduction of blood sugar levels when used together and can lower the risk of hypoglycemia and help in better reduction of body weight.
Yes, there are some cases of Onglyza-induced heart failure reported especially in patients with additional risk factors for heart failure. In case the patient develops symptoms of heart failure like increasing shortness of breath, the rapid increase in weight and swelling of the feet (pedal edema). Stop taking Onglyza and inform your doctor.
Onglyza is indicated along with dietary modification and exercise in adults with type 2 diabetes mellitus. It is seen to significantly reduce blood glucose levels and glycosylated hemoglobin (HbA1c) when taken as a single drug or in combination with other anti-diabetic drugs.
Q. What is the difference between Onglyza and alogliptin?
Both, Onglyza and alogliptin are antidiabetic drugs of same class. They are similar in terms of efficacy and safety. The only difference is that Alogliptin is longer acting than Onglyza, still, both are given once a day.
Q. What is the difference between Onglyza and glimepiride?
Both Glimepiride and Onglyza are antidiabetic drugs but they belong to different classes and have different side effect profiles. Glimepiride commonly causes hypoglycemia and weight gain while Onglyza causes a headache and nasopharyngitis.
Q. Is Onglyza better than sitagliptin?
Onglyza and Sitagliptin and belong to the same class of drugs and are equally effective and safe in the treatment of type 2 diabetes mellitus. For severely compromised renal patients dosage adjustment is required for both drugs but with mild to moderate renal impairment no dosage adjustment is required with sitagliptin.
Q. Is Onglyza better than linagliptin?
Both Onglyza and linagliptin belong to the same class of drugs with a similar mechanism of action and efficacy to lower blood sugar levels and HbA1c. However, linagliptin is safe to use in patients with underlying kidney disease while a dose adjustment is needed in patients with moderate to severe renal failure with Onglyza.
Q. Is it beneficial to use Onglyza with glipizide?
Yes, it is beneficial to take Onglyza and glipizide. Both are antidiabetic drugs, however, they work in different ways. When taken together, they can help in better control of blood sugar levels. However, the risk of low blood sugar levels (hypoglycemia) can increase if the dose of glipizide is not adjusted.
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