Normapac 25mg Tablet

Loxapine (25mg)

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Normapac 25mg Tablet is used in the treatment of schizophrenia. It may also be used to treat depression and bipolar disorder. It alters the thoughts and elevates the mood, improving the person’s ability to think, feel and behave.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 25 Nov 2025 | 03:05 PM (IST)

₹80.7 MRP ₹88.559% off

Gurgaon

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General Information

Contains

Loxapine (25mg)

Marketer

Mankind Pharma Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Normapac 25mg Tablet should be taken with food, preferably at the same time each day. Take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration as advised by your doctor and if you have missed a dose, take it as soon as you remember it. Do not skip any doses and finish the full course of treatment even if you feel better. This medication mustn't be stopped suddenly without talking to your doctor as it may worsen your symptoms.

Some common side effects of this medicine include dry mouth, abnormality of voluntary movements, urinary retention, constipation, and muscle rigidity. Initially, this medicine may cause a sudden drop in blood pressure when you change positions, rise slowly if you have been sitting or lying down. It may also cause dizziness and sleepiness, do not drive or do anything that requires mental focus until you know how this medicine affects you.

Before taking it, inform your doctor if you are suffering from thyroid or kidney problems, epilepsy, Parkinson’s disease, glaucoma, or any heart problems. You should not take this medicine if you are under the influence of alcohol or any sleep-inducing, cough, and/ or allergy medication. This medicine can also lead to weight gain, eat a healthy balanced diet, avoid snacking with high-calorie food, and exercise regularly.

Uses of Normapac Tablet

Benefits of Normapac Tablet

Treatment of Depression
Normapac 25mg Tablet helps in maintaining the balance of certain chemicals in the brain that affect mood and behavior. This improves your mood, relieves anxiety, tension, helps you sleep better, and increases your energy levels. Normapac 25mg Tablet prevents extreme changes in mood and helps you feel less agitated. You may experience fewer episodes of depression and low mood.

Treatment of Schizophrenia
Schizophrenia is a mental disorder in which a person’s thinking ability, feelings, and behavior become abnormal. Normapac 25mg Tablet helps restore the chemical imbalances in the brain that are responsible for such changes. It improves thoughts, behavior and enhances the quality of life.

Treatment of Bipolar disorder
Normapac 25mg Tablet works to restore the normal balance of nerve activity in your brain. It can help prevent extreme changes in mood and help you feel less agitated. You may experience fewer episodes of low mood. It can take several weeks for this medicine to work and you may still feel low during this time. It is likely that you will take this medicine for at least six months but possibly much longer. It needs to be taken regularly to work effectively. Do not stop taking it unless your doctor advises you to. You should continue to eat well and keep fit to reduce symptoms of bipolar disorder.

Side effects of Normapac Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Normapac

Sleepiness
Orthostatic hypotension (sudden lowering of blood pressure on standing)
Dryness in mouth
Abnormality of voluntary movements
Weight gain
Increased prolactin level in blood
Urinary retention
Constipation
Muscle stiffness
Tremors

How to use Normapac Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Normapac 25mg Tablet should be taken with or after food.

How Normapac Tablet works

Normapac 25mg Tablet is a typical antipsychotic. It works by blocking the action of dopamine, a chemical messenger in the brain that affects thoughts and mood.

Quick tips

Normapac 25mg Tablet should be taken with food, preferably at the same time every day.
Use caution while driving or doing anything that requires concentration as Normapac 25mg Tablet can cause dizziness and sleepiness.
Immediately inform the doctor if the person taking Normapac 25mg Tablet starts to have breathing problems.
Older people who have memory loss and psychosis have a higher risk of death if they take Normapac 25mg Tablet.
Do not stop taking the medicine without talking to your doctor as it can worsen the condition.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Normapac 25mg Tablet

Pregnancy

CONSULT YOUR DOCTOR

The safety of Normapac 25mg Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding

CONSULT YOUR DOCTOR

Normapac 25mg Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.

Driving

UNSAFE

Normapac 25mg Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

SAFE IF PRESCRIBED

Normapac 25mg Tablet is probably safe to use in patients with kidney disease. Limited data suggest dose adjustment may not be needed.

Liver

SAFE IF PRESCRIBED

Normapac 25mg Tablet is probably safe to use in patients with liver disease. Limited data suggest dose adjustment may not be needed.

Interaction with drugs

Taking Normapac with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Moderate

Memantine (Oral Route)

Your doctor may monitor your treatment and adjust the doses as per the observations. Memantine may reduce efficacy of Loxapine.

Moderate

Alprazolam (Oral Route)

Talk to your doctor if you notice any unusual symptoms.

Moderate

Zolpidem (Oral Route)

Talk to your doctor if you notice any unusual symptoms.

Moderate

Clozapine (Oral Route)

Watch out for symptoms such as dry mouth, increased heart rate, urination difficulties, constipation, loss of appetite, or nausea, and consult your doctor if you experience them. If you experience dizziness or faintness while standing, it is recommended to get up more slowly.

Moderate

Diazepam (Injection Route)

Talk to your doctor if you notice any unusual symptoms.

Frequently asked questions

What is Normapac 25mg Tablet used for?

Normapac 25mg Tablet is an antipsychotic medicine used to treat schizophrenia and other mental health conditions. It helps reduce symptoms like delusions, hallucinations, and disorganized thinking.

What are the serious side effects of Normapac 25mg Tablet?

Serious side effects of Normapac 25mg Tablet may include uncontrolled muscle movements (tardive dyskinesia), high fever and muscle stiffness (neuroleptic malignant syndrome), seizures, and heart rhythm problems. You should seek immediate medical attention if you notice any of these symptoms.

Who should not take Normapac 25mg Tablet?

Individuals should not take Normapac 25mg Tablet if they are allergic to loxapine or any ingredients present in Normapac 25mg Tablet, have a history of seizures, have severe breathing or heart problems, are in a coma, or are taking strong sedatives.

Can Normapac 25mg Tablet cause withdrawal symptoms?

Yes. Suddenly stopping Normapac 25mg Tablet can cause withdrawal symptoms such as nausea, vomiting, dizziness, and return of mental health symptoms. Your doctor will help you stop it gradually if needed.

Is Normapac 25mg Tablet safe for elderly people with dementia?

No. Normapac 25mg Tablet is not recommended for older adults with dementia-related psychosis, as it may increase the risk of stroke or death.

Can Normapac 25mg Tablet affect my ability to drive or use machines?

Yes. Normapac 25mg Tablet can make you feel drowsy or dizzy. Avoid driving or operating machinery until you know how the medicine affects you.

What precautions should I take while on Normapac 25mg Tablet?

While taking Normapac 25mg Tablet, you should drink plenty of water, avoid dehydration, stand up slowly to avoid dizziness, and inform your doctor about any heart, kidney, or liver conditions.

Fact Box

Chemical Class

Dibenzoxazepines

Habit Forming

Therapeutic Class

NEURO CNS

Action Class

Typical Antipsychotics

References

Stahl SM, editor. Loxapine. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 377-82.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 825-26.
Loxapine [FDA Label]. Mountain View, CA: Alexza Pharmaceuticals, Inc.; 1975. [Accessed 02 Mar. 2020] (online) Available from:
Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Loxapine. [Updated 2018 Oct 31]. [Accessed 20 Feb. 2020] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 25 Mar. 2019] (online) Available from:

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Mankind Pharma Ltd
Address: 208, Okhla Industrial Estate, Phase III, New Delhi - 110020

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Normapac 25mg Tablet

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Normapac Tablet

Benefits of Normapac Tablet

Side effects of Normapac Tablet

How to use Normapac Tablet

How Normapac Tablet works

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Memantine (Oral Route)

Alprazolam (Oral Route)

Zolpidem (Oral Route)

Clozapine (Oral Route)

Diazepam (Injection Route)

Frequently asked questions

What is Normapac 25mg Tablet used for?

What are the serious side effects of Normapac 25mg Tablet?

Who should not take Normapac 25mg Tablet?

Can Normapac 25mg Tablet cause withdrawal symptoms?

Is Normapac 25mg Tablet safe for elderly people with dementia?

Can Normapac 25mg Tablet affect my ability to drive or use machines?

What precautions should I take while on Normapac 25mg Tablet?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

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