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Noritop 10 Tablet

Nortriptyline (10mg)
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Noritop 10 Tablet is a tricyclic antidepressant that is used to treat depression and nighttime bedwetting (nocturnal enuresis). Additionally, it may also be prescribed for neuropathic pain.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 02 Feb 2026 | 11:11 AM (IST)
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General Information

The content is shown in English
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Product introduction

Noritop 10 Tablet works by increasing the levels of chemical messengers in the brain that stabilizes and enhances the mood. It is better to take it before bedtime because it can make you feel drowsy. It can be taken with or without food, but you should take it at a fixed time each day for better efficacy. The dose and duration will be decided by your doctor so that you get the right amount to control your symptoms. 

The most common side effects of this medicine include increased heart rate, blurred vision, dryness in the mouth, difficulty in urination, and constipation. Initially, this medicine may also cause a sudden drop in blood pressure when you change positions. It may even cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. To lower the chance of dizziness, rise slowly if you have been sitting or lying down. It may also lead to weight gain in some people. Most of the common side effects tend to be mild and temporary. Your doctor may be able to suggest ways of preventing or reducing side effects if they bother you or do not go away. Serious side effects associated with this medicine are rare.

Before taking this medicine, it is important to tell your doctor if you are taking or have recently taken any other medicines for the same or any other diseases. Pregnant and breastfeeding women should take this medicine with proper consultation and caution. This medicine is not known to be addictive, but you can experience additional side effects (withdrawal symptoms) if you stop taking it suddenly. If you notice any sudden mood change or get suicidal or self-harm thoughts, you must consult the doctor without delay. Also, remember to take this medicine strictly as advised by the doctor as an overdose of this medication may lead to a serious health emergency. Consumption of alcohol should be avoided as alcohol interacts with this medicine to cause serious health issues.

Uses of Noritop Tablet

Benefits of Noritop Tablet

Bed-wetting
Bed-wetting in children or adults can be distressing and affect sleep and confidence. Noritop 10 Tablet helps by reducing bladder overactivity at night, leading to fewer episodes of bed-wetting and improved sleep quality.
Depression
Depression is a condition marked by persistent sadness, loss of interest, and low energy that disrupts daily life. Noritop 10 Tablet helps lift mood, restore interest in activities, and improve overall emotional balance, supporting better mental health and well-being.
Neuropathic pain
Neuropathic pain is caused by nerve damage and may feel like burning, tingling, or shooting pain, often disturbing daily life. Noritop 10 Tablet reduces this nerve-related pain, improving comfort and allowing for better sleep and daily functioning.

Side effects of Noritop Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Noritop
  • Decreased libido
  • Tremors
  • Confusion
  • Fatigue
  • Dilatation of pupil
  • Nausea
  • Agitation
  • Constipation
  • Orthostatic hypotension (sudden lowering of blood pressure on standing)
  • Weight gain
  • Taste change
  • Paresthesia (tingling or pricking sensation)
  • Loss of accommodation
  • Palpitations
  • Atrioventricular block
  • Nasal congestion (stuffy nose)
  • Dryness in mouth
  • Abnormal ECG
  • Headache
  • Abnormality of voluntary movements
  • Erectile dysfunction

How to use Noritop Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Noritop 10 Tablet may be taken with or without food.

How Noritop Tablet works

Noritop 10 Tablet is a tricyclic antidepressant. It increases the levels of chemical messengers in the brain that help in regulating the mood and treat depression.

All substitutes for Noritop 10 Tablet

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

  • Noritop 10 Tablet is used for the treatment of depression and bedwetting in children.
  • The main dose should be taken at night as this drug may cause drowsiness or sleepiness.
  • You may be asked for regular blood tests to monitor the blood cell count or level of sodium and sugar in the blood.
  • Inform your doctor if you notice behavioral changes, mood changes and suicidal thoughts while taking this medicine. 
  • Do not drive or do anything that requires concentration until you know how the medicine affects you.
  • Do not stop taking the medication suddenly without talking to your doctor.
  • The main dose should be taken at night as this medicine may produce drowsiness or sleepiness.
  • It can take 2 to 3 weeks for Noritop 10 Tablet to start working.
  • You should continue the treatment for at least 6 months after you feel better to stop depression from coming back.
  • If your doctor asks you to stop Noritop 10 Tablet, you should reduce the dose slowly over 4 weeks. You should not discontinue it abruptly.
  • Avoid driving or operating machinery as it may decrease alertness.
  • Avoid consuming alcohol when taking the Noritop 10 Tablet, as it may cause excessive drowsiness and calmness.
  • The addiction/dependence potential of Noritop 10 Tablet is very less.
  • It may be extremely dangerous in overdose. 

Safety advice

Alcohol

Alcohol

UNSAFE
Do not drink alcohol while you are taking this medicine. Noritop 10 Tablet may cause excessive drowsiness when taken with alcohol.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Noritop 10 Tablet is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.
Breast feeding

Breast feeding

CAUTION
Noritop 10 Tablet should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from the body.
Driving

Driving

UNSAFE
Noritop 10 Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
As Noritop 10 Tablet may affect your alertness which may affect your ability to drive.
Kidney

Kidney

CAUTION
Noritop 10 Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Liver

Liver

CAUTION
Noritop 10 Tablet should be used with caution in patients with severe liver disease. Dose adjustment may be needed.
Inform your doctor if you develop any signs and symptoms of jaundice while taking this medicine. Use of Noritop 10 Tablet is not recommended in patients with severe liver disease.

Interaction with drugs

Taking Noritop with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Life-threatening

Moclobemide (Oral Route)

Do not consume Moclobemide with Nortriptyline. If Moclobemide is essential, ensure a gap of at least 1 day after discontinuing Nortriptyline. Please consult your doctor.
Life-threatening

Domperidone (Oral Route)

Do not consume Domperidone with Nortriptyline.
Life-threatening

Tranylcypromine (Oral Route)

Do not consume Tranylcypromine with Nortriptyline. If Tranylcypromine is essential, ensure a gap of at least 2 weeks after discontinuing Nortriptyline. Please consult your doctor.
Severe

Tramadol (Injection Route)

Careful consideration is advised if you have epilepsy. Watch out for symptoms of serotonin syndrome, such as sedation, respiratory impairment, tremors, fever, diarrhea, or agitation, and consult your doctor if you experience them. Your doctor may alter or discontinue the medicines accordingly.
Severe

Thioridazine (Oral Route)

If concurrent use is essential, watch out for symptoms such as sleepiness, dry mouth, impaired voluntary movements, weight gain, constipation, muscle stiffness or tremors and consult your doctor if you experience them. Factors such as old age, chronic heart issues, or low potassium levels may more frequently cause disturbance in heart rhythm, and your doctor may consider ECG monitoring in their presence.

Frequently asked questions

Noritop 10 Tablet is used to treat depression and nocturnal (night time) bedwetting in children. It restores the chemical imbalance in the brain and enhances mood and behavior. In some cases, it may also be prescribed to relieve neuropathic (nerve) pain.
Yes, Noritop 10 Tablet can be taken for nerve pain. Your doctor may prescribe this medicine in combination with gabapentin. Nerve pain (or neuropathic pain) is commonly described as a shooting, burning or stabbing type of pain that may be associated with tingling, numbness or a pin and needles like feeling. The pain may be spontaneous which means it may be triggered without the presence of any stimulating factor. Additionally, you may experience an increase in the sensitivity to touch. Consult your doctor if you experience such pain.
The side effects of Noritop 10 Tablet are increased heart rate, weight gain, difficulty in urination, orthostatic hypotension (sudden decrease in blood pressure on standing), dryness in mouth and constipation. Please consult your doctor if these side effects do not go away or worry you.
Noritop 10 Tablet and amitriptyline belong to the same category of medicines with similar action, but their effect may vary upon individual response.
Noritop 10 Tablet is safe if used in the dose and duration advised by your doctor. Take it exactly as directed and do not skip any dose. Follow your doctor's instructions carefully and let your doctor know if any of the side effects bother you.
No, you must not stop taking Noritop 10 Tablet suddenly even if you are feeling better as it may worsen your condition. It may also cause withdrawal symptoms such as dizziness, nausea, vomiting, headache, weakness, sleep problems, fever and irritability. Continue taking Noritop 10 Tablet for the duration prescribed by your doctor to get maximum benefit. If any of the side effects are bothering you, consult your doctor. In case you have completed your course of treatment, your doctor will reduce your dose gradually before taking you off this medicine completely.
Noritop 10 Tablet may cause drowsiness and dizziness, especially in the beginning of the treatment. Do not drive or work with tools or machinery if your alertness is affected. It is not advisable to drink alcohol during treatment with this medicine as it might worsen the drowsiness. Tell your doctor if you have any problems with your liver or kidneys. Let your doctor know about all the other medicines you are taking because they may affect, or be affected by, this medicine. Inform your doctor if you are pregnant, planning to conceive or breastfeeding to prevent any harmful effects on the baby.
Yes, Noritop 10 Tablet can cause urinary problems. It is more commonly seen in elderly people who are above 65 years of age. The person may face difficulty in passing urine which can further lead to a urinary tract infection. You should consult your doctor immediately if you develop these symptoms.
An overdose of Noritop 10 Tablet can be significantly dangerous. In case of an overdose, you may experience symptoms such as blurred vision, fast or irregular heartbeats, dry mouth and tongue, fits and fever. You may also experience agitation (anxiety), confusion, hallucinations, uncontrolled movements, low blood pressure, difficulty breathing, discoloration of the skin (turning blue), drowsiness, loss of consciousness, or you may even go into a state of coma. Immediately consult your doctor and seek medical help if you have taken more than the recommended amount of Noritop 10 Tablet.
If you have missed a dose of Noritop 10 Tablet, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take the next scheduled dose. Do not double the dose to make up for the missed one as this may increase the chances of developing side effects.
Before taking Noritop 10 Tablet, you should tell your doctor if you are allergic to Noritop 10 Tablet or any of its ingredients to avoid any allergic reactions. Inform your doctor if you have any problems with your heart, liver, thyroid, prostate or kidneys. Tell your doctor if you have or ever had epilepsy (seizures or fits), diabetes, or glaucoma. Let your doctor know about all the other medicines you are taking because they may affect, or be affected by, this medicine. Also, inform your doctor if you are pregnant, planning to conceive or breastfeeding to prevent any harmful effects on the baby.
Yes, Noritop 10 Tablet is effective if taken in the dose and duration prescribed by the doctor. Do not consume more than the recommended dose and avoid skipping doses. Inform your doctor if you experience any side effects while taking Noritop 10 Tablet to know about ways to manage or prevent them. It may take a few weeks for you to see improvement in your symptoms. However, the treatment may be continued for a few months for effective management of your condition.

Fact Box

Chemical Class

Dibenzocycloheptenes

Habit Forming

No

Therapeutic Class

NEURO CNS

Action Class

Tricyclic Antidepressants (TCAs)

References

  1. Stahl SM, editor. Nortriptyline. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 477-83.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1006-1007.
  3. Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 25 Mar. 2019] (online) Available from:
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Tas Med India Pvt Ltd
Address: Plot No. 45, N.T.M., Sector -26, Chandigarh

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Noritop 10 Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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