Monolith 400mg Tablet SR

Prescription Required
Storage
Store at room temperature (10-30°C)

Introduction

Monolith 400mg Tablet SR is used in the treatment of bipolar disorder and mania in adults. It is sometimes used to treat other behavioral disorders as well. It reduces the frequency of manic episodes and decreases the intensity of those episodes that might occur.

Monolith 400mg Tablet SR should be taken with food. However, it is advised to take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Do not skip any doses and finish the full course of treatment even if you feel better. If you have missed a dose, take it as soon as you remember it. You should continue to take this medicine for as long as the doctor advises and do not stop taking it suddenly as it may result in harmful effects.

Side effects associated with the use of this medicine include tremors, slurred speech, uncoordinated body movements, nausea, acne, increased white blood cell count, and memory impairment. It may also cause hair loss, enlarged thyroid gland, skin rash, and increased thirst. This medicine may also cause weight gain and to control it, you should have a balanced diet and exercise regularly. If you have been taking this medicine for a long time then regular monitoring of thyroid and kidney function may be required.

Uses of Monolith Tablet SR

Benefits of Monolith Tablet SR

In Mania

Mania means extremely excited or elevated mood. Monolith 400mg Tablet SR helps calm the mood and relax the nerves. This stabilises the mood and prevents the symptoms of mania from recurring again. Taking Monolith 400mg Tablet SR will ensure that you have a better social life and are able to do daily activities more comfortably.

In Bipolar disorder

Monolith 400mg Tablet SR works to restore the normal balance of nerve activity in your brain. It can help prevent extreme changes in mood and help you feel less agitated. You may experience fewer episodes of low mood. It can take several weeks for this medicine to work and you may still feel low during this time. It is likely that you will take this medicine for at least six months but possibly much longer. It needs to be taken regularly to work effectively. Do not stop taking it unless your doctor advises you to. You should continue to eat well and keep fit to reduce symptoms of bipolar disorder.

Side effects of Monolith Tablet SR

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Monolith

  • Tremor
  • Slurred speech
  • Uncoordinated body movements
  • Nausea
  • Acne
  • Increased white blood cell count
  • Memory impairment
  • Hair loss
  • Goiter (enlarged thyroid gland)
  • Skin rash
  • Increased thirst
  • Weight gain
  • Polyuria
  • Diarrhea

How to use Monolith Tablet SR

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Monolith 400mg Tablet SR is to be taken with food.

How Monolith Tablet SR works

Monolith 400mg Tablet SR works by suppressing the abnormal and excessive activity of the nerve cells in the brain.

Safety Advice

Alcohol
UNSAFE
It is unsafe to consume alcohol with Monolith 400mg Tablet SR.
Pregnancy
CONSULT YOUR DOCTOR
Monolith 400mg Tablet SR is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breastfeeding
SAFE IF PRESCRIBED
Monolith 400mg Tablet SR is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving
UNSAFE
Monolith 400mg Tablet SR may cause side effects which could affect your ability to drive.
Monolith 400mg Tablet SR may make you feel sleepy, tired or dizzy. Monolith 400mg Tablet SR may also cause other effects that can make it dangerous to drive such as numbness, paralysis, weakness or fits (seizures).
Kidney
CAUTION
Monolith 400mg Tablet SR should be used with caution in patients with kidney disease. Dose adjustment of Monolith 400mg Tablet SR may be needed. Please consult your doctor.
Use of Monolith 400mg Tablet SR is not recommended in patients with severe kidney disease.
Liver
SAFE IF PRESCRIBED
Monolith 400mg Tablet SR is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Monolith 400mg Tablet SR may not be needed in these patients. Please consult your doctor.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Monolith 400mg Tablet SR
₹6.5/Tablet SR
Elith SR 400mg Tablet
Elikem Pharmaceuticals Pvt Ltd
₹1.9/Tablet SR
71% cheaper
Litholite 400mg Tablet SR
Elite Pharma Pvt Ltd
₹2/Tablet SR
69% cheaper
Lithopik 400mg Tablet SR
Aarpik Pharmaceuticals Pvt Ltd
₹2.39/Tablet SR
63% cheaper
Lithoset 400mg Tablet SR
Tweet India Pharmaceuticals Pvt Ltd
₹2.52/Tablet SR
61% cheaper
Lithoril 400mg Tablet SR
Reliance Formulation Pvt Ltd
₹2.57/Tablet SR
60% cheaper

Quick Tips

  • Monolith 400mg Tablet SR is one of the most effective long-term treatment for bipolar disorder.
  • It may also be used for the treatment of mania.
  • Your lithium blood levels, thyroid function, and kidney function may be monitored as long as you take this medicine.
  • It may cause diarrhea and dehydration. Drink plenty of water and and use normal amounts of salt. Inform your doctor if you start or stop a low-salt diet.
  • Monitor your weight during treatment as Monolith 400mg Tablet SR can cause weight gain.
  • Do not drive or do anything that requires mental focus until you know how it affects you.
  • Inform your doctor if you have persistent stomach upset, problems with your speech, or extreme drowsiness. Your dose may need to be adjusted.
  • Do not take Monolith 400mg Tablet SR if you are pregnant or breastfeeding.
  • Do not stop taking the medication suddenly without talking to your doctor.

Fact Box

Chemical Class
Organic Carbonic Acids
Habit Forming
No
Therapeutic Class
NEURO CNS
Action Class
Mood stabilizers

Interaction with Drugs

Taking Monolith with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Art-X, Cardasol, Amione
LIFE-THREATENING
Brand(s): SIB Trim, Deobese, Sibunet
LIFE-THREATENING
Brand(s): Acetazide, Actazid, AZ Mide
SERIOUS
Brand(s): Stozen
SERIOUS

Patient Concerns

arrow
I an suffering from mania what should i do.
Dr. Jyoti Kapoor Madan
Psychiatry
Mania is a component of Bipolar Affective Disorder. Bipolar Affective Disorder is a chronic problem caused by Neuro chemical disturbance in brain. It is characterised by excessive mood swings leading to disruption in routine life. Treatment is with mood stabilizer medicines and antipsychotic medicines which may need to continue throughout life. Please see a psychiatrist for further guidance.
Suffering from Depression and Mania, what should be done
Dr. Jyoti Kapoor Madan
Psychiatry
Bipolar Affective Disorder is a chronic problem caused by Neuro chemical disturbance in brain. It is characterised by excessive mood swings leading to disruption in routine life. Treatment is with mood stabilizer medicines and antipsychotic medicines which may need to continue throughout life. Please see a psychiatrist for further guidance.
arrow
Do you have any questions related to Monolith 400mg Tablet SR ?

User Feedback


FAQs

Q. How quickly does Monolith 400mg Tablet SR work?

It takes some time before you see improvement in your symptoms after taking Monolith 400mg Tablet SR. Though it varies from person to person, it may take 1-3 weeks or longer for you to see the full benefits of Monolith 400mg Tablet SR. Do not stop taking Monolith 400mg Tablet SR if you feel you are not improving. Instead, discuss it with your doctor.

Q. Does Monolith 400mg Tablet SR make you sleepy?

Yes, Monolith 400mg Tablet SR can cause nervous system disorders like sleepiness and dizziness and feeling confused. It can also cause rapid eye movements, blurred vision, or blind spots in your eyesight. If you experience any of these symptoms, consult your doctor. In addition, avoid driving or operating heavy machinery as it can be hazardous for you.

Q. Is Monolith 400mg Tablet SR bad for kidneys?

Yes, Monolith 400mg Tablet SR may cause kidney problems. Monolith 400mg Tablet SR is not prescribed in patients who already have severe kidney impairment. The kidney problems may not be reversible and the symptoms include swollen ankles, passing a lot of urine and feeling thirsty. Before starting treatment with Monolith 400mg Tablet SR, your doctor will get blood tests done to see if your kidney function is normal. During Monolith 400mg Tablet SR therapy, any gradual or sudden changes in renal function, even within the normal range, may indicate the need for re-evaluation of treatment.

Q. Can Monolith 400mg Tablet SR cause gain in weight?

Monolith 400mg Tablet SR can cause both weight gain or weight loss. You should keep a check on your weight during Monolith 400mg Tablet SR therapy. If you feel you are gaining or losing too much weight, consult your doctor who will assess whether the change in weight is due to Monolith 400mg Tablet SR or some other reason.

Q. What is the most important information I should know about Monolith 400mg Tablet SR?

Monolith 400mg Tablet SR therapy should only be started if adequate facilities for assessing Monolith 400mg Tablet SR levels are available. This is because Monolith 400mg Tablet SR toxicity is related to increased levels of Monolith 400mg Tablet SR in blood. Monolith 400mg Tablet SR toxicity can even occur at dose which is effective for treatment. Therefore, your doctor may closely monitor your Monolith 400mg Tablet SR levels weekly until stabilization is achieved, then weekly for one month and then at monthly intervals thereafter.

Q. How should Monolith 400mg Tablet SR be taken?

Take Monolith 400mg Tablet SR exactly as prescribed by your doctor. Check with your doctor if you are not sure. It is meant for oral administration and can be taken with or without food. However, if you start following a certain type of diet, talk to your doctor first. Any drastic changes in the amount of water you drink or amount of sodium (salt) in your diet may require more frequent monitoring of Monolith 400mg Tablet SR levels.

Q. Which medicines decrease Monolith 400mg Tablet SR levels?

You should inform your doctor about the medicines you are taking before starting Monolith 400mg Tablet SR since many medicines interfere with the working of Monolith 400mg Tablet SR. Some medicines decrease the levels of Monolith 400mg Tablet SR in blood which means that it will not work well. These include theophylline (for asthma), caffeine, anything containing sodium bicarbonate, or a special group of diuretics (water tablets) called carbonic anhydrase inhibitors and urea used to treat skin conditions.

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Disclaimer:

1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Stahl SM, editor. Lithium. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 349-54.
  2. Meltzer H. Antipsychotic Agents & Lithium. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 502-504.
  3. Drugs.com. Lithium Pregnancy and Breastfeeding Warnings. [Accessed 25 Mar. 2019] (online) Available from:External Link
  4. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Lithium. [Updated 2020 Jan 20]. [Accessed 20 Feb. 2020] (online) Available from:External Link
  5. Central Drugs Standard Control Organisation (CDSCO). [Accessed 25 Mar. 2019] (online) Available from:External Link

Manufacturer/Marketer Address

Consern Pharma Private Limited, Kuljive Mahajan(Mg. Director), Rural Focal Point, V.P.O. Tibba, Ludhiana - 141120, Punjab, India
Country of Origin: India

MRP
65
Inclusive of all taxes
10 tablet sr in 1 strip
SOLD OUT

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