Microgest 50mg Injection

Reviewed By Dr. Mekhala Chandra, MD, MBBS

Last updated on 23 Jan 2026 | 03:47 PM (IST)

Microgest 50mg Injection provides progesterone, which is a natural hormone essential for reproductive health. It is used to support pregnancy in female infertility and as part of hormone replacement therapy. It helps regulate the menstrual cycle, prepares the uterus for pregnancy, and balances hormones.

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Microgest 50mg Injection

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Aqsusten 50 Injection

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Progesterone (50mg)

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General Information

Contains

Progesterone (50mg)

Marketer

Walter Bushnell

Storage

Store below 30°C

The content is shown in English

Product introduction

You should use Microgest 50mg Injection as your doctor has advised. It is given as an injection by a healthcare professional. Do not exceed the prescribed dose or use it for longer than recommended. Your doctor may advise you to continue receiving this injection for a certain period after pregnancy is confirmed.

The most common side effects include headache, back pain, dizziness, weight gain, vaginal discharge, stomach cramps, pain or swelling in your abdomen, and feeling sick. You may also feel bloated, less interested in sex, and get pain or discharge in your vagina. Your doctor or nurse may be able to help you reduce or prevent side effects if they bother you or do not go away. Very occasionally, people get a severe allergic reaction that needs urgent medical attention.

Microgest 50mg Injection may not suit everybody, and you should tell your doctor if you have, or have had, breast cancer, unusual bleeding in the vagina, or liver disease. You may be monitored more carefully if you have liver, kidney, or heart problems, or have diabetes or asthma.

Let your doctor know your medical history. Check with your doctor about all other medicines that may affect, or be affected by, this medicine. You will probably have several tests both before and during treatment to check your womb. In general, alcohol is not recommended while taking this medicine.

Uses of Microgest Injection

Benefits of Microgest Injection

Female infertility
Microgest 50mg Injection contains progesterone, a female hormone that is important in the regulation of ovulation and menstruation. It is used to cause menstrual periods in women who have not reached menopause but are not having periods due to a lack of natural progesterone in the body. This medicine helps to prepare the uterus for pregnancy by causing the uterus lining (endometrium) to thicken. This increases the chance of a successful pregnancy. You should use the medicine as prescribed for it to be effective. You may be asked to continue with this treatment for a period after becoming pregnant.

Hormone replacement therapy
Hormone placement therapy (HRT) is a treatment to relieve symptoms of menopause such as hot flushes, night sweats, mood swings, vaginal dryness, and reduced sex drive. Since menopause can last for several years, this treatment can make a big improvement to your daily life and mood. Progesterone is one of two important hormones (the other being is estrogen) used in this treatment. However it may not treat all your symptoms, consult with your doctor. You should use this medicine as it is prescribed, and for as long as it is prescribed by your doctor.

Side effects of Microgest Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Microgest

Nervousness
Decreased libido
Anorgasmia (decreased orgasm)
Depression
Insomnia (difficulty in sleeping)
Headache
Dizziness
Flushing (sense of warmth in the face, ears, neck and trunk)
Abdominal pain
Abdominal discomfort
Abdominal distension
Nausea
Back pain
Leg cramps
Irregular uterine bleeding
Vaginal discharge
Breast pain
Breast tenderness
Pain during periods
Pelvic pain
Vaginal inflammation
Edema (swelling)
Weakness
Fatigue
Change in body weight

How to use Microgest Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Microgest Injection works

Microgest 50mg Injection works by preparing the uterus for pregnancy and maintaining a healthy environment for fetal development. It thickens the uterine lining to support implantation and prevents contractions that could lead to early pregnancy loss. Additionally, it helps regulate the menstrual cycle and balances other reproductive hormones. In hormone therapy, it supports overall hormonal stability and helps manage symptoms related to hormonal imbalances.

All substitutes for Microgest 50mg Injection

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

Do not self-administer unless advised. Only inject at home if your doctor has trained you properly.
Let your doctor know if you have any history of blood clots, breast cancer, or liver issues before starting treatment.
Your doctor may schedule hormone level tests or scans to monitor your response to treatment. Make sure to attend all scheduled appointments for best results.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Microgest 50mg Injection. Please consult your doctor.

Pregnancy

SAFE IF PRESCRIBED

Microgest 50mg Injection is safe to use during pregnancy. Most studies have shown low or no risk to the developing baby.

Breast feeding

SAFE IF PRESCRIBED

Available human data suggest that the drug does not pass into breast milk in clinically significant amounts and is unlikely to harm the infant.

Driving

UNSAFE

Microgest 50mg Injection may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CONSULT YOUR DOCTOR

There is limited data available on the use of Microgest 50mg Injection in patients with kidney disease. Please consult your doctor.

Liver

CAUTION

Microgest 50mg Injection should be used with caution in patients with liver disease. Dose adjustment may be needed.
Use of Microgest 50mg Injection is however not recommended in patients with severe liver disease.

Interaction with drugs

Taking Microgest with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Severe

Tamoxifen (Oral Route)

Do not consume Tamoxifen with Progesterone if you have or had breast cancer. If essential, consult your doctor.

Severe

Letrozole (Oral Route)

Do not consume Letrozole with Progesterone if you have or had breast cancer. If essential, consult your doctor.

Severe

Lorlatinib (Oral Route)

Do not consume Lorlatinib with Progesterone. Lorlatinib may reduce blood levels of Progesterone.

Severe

Anastrozole (Oral Route)

Do not consume Anastrozole with Progesterone if you have or had breast cancer. If essential, consult your doctor. Progesterone may reduce the efficacy of Anastrozole.

Severe

Darunavir (Oral Route)

It is recommended to use barrier methods (like condoms), IUDs, or a depot for contraception. Your doctor may monitor your treatment closely and adjust the doses as per the observations. Use barrier methods (like condoms) for contraception to reduce the risk of HIV infection.

Frequently asked questions

What is Microgest 50mg Injection?

Microgest 50mg Injection contains progesterone, which is a natural female sex hormone. It is used to treat menstrual and pregnancy-related issues that are caused by hormonal imbalances. It may also be prescribed along with estrogen as a part of hormonal replacement therapy for preventing endometrial hyperplasia (thickening of the lining of the uterus).

What does Microgest 50mg Injection treat?

Microgest 50mg Injection is used to treat various disorders. It is given to women with secondary amenorrhea (no menstruation for 3 months in women who have had their menses before). It is used to support pregnancy, prevent premature labor, and treat bleeding disorders that may occur before menopause. It may be used as a part of fertility treatment and may be given as hormone replacement therapy after menopause. It is also given to relieve symptoms of premenstrual syndrome and painful bleeding, like dysfunctional uterine bleeding.

How and in what dose should I take Microgest 50mg Injection?

Microgest 50mg Injection is to be given by a doctor or nurse only. It is given as an injection into the muscle. The dose will depend on the condition you are being treated for and will be decided by your doctor. Follow your doctor’s instructions carefully to get maximum benefit from Microgest 50mg Injection.

Does Microgest 50mg Injection cause weight gain?

Yes, the use of Microgest 50mg Injection may cause weight gain. The reason for this weight gain could be water retention. However, this may not be a serious sign. If you are concerned about weight gain, contact your doctor.

How is Microgest 50mg Injection beneficial for fertility and pregnancy?

Microgest 50mg Injection consists of progesterone, which is important for fertility. Progesterone is the hormone secreted by the ovaries that helps prepare the uterus for pregnancy and also maintains it. Microgest 50mg Injection is given in cases of infertility to support the uterus in preparing itself for the pregnancy and to prevent abortions in some cases. It is also used to prevent premature labor.

Is Microgest 50mg Injection effective?

Microgest 50mg Injection is effective if used in the dose and duration advised by your doctor. Do not stop taking it even if you see improvement in your condition. If you stop using Microgest 50mg Injection too early, the symptoms may return or worsen.

Fact Box

Chemical Class

Gluco/mineralocorticoids, progestogin derivative

Habit Forming

Therapeutic Class

GYNAECOLOGICAL

Action Class

Natural Progesterone

Related lab tests

Anti Mullerian Hormone

Glycosylated Hemoglobin

Testosterone Total

Thyroid Stimulating Hormone

References

Chrousos GP. The Gonadal Hormones & Inhibitors. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 706-707.
Levin ER, Hammes SR. Estrogens and Progestins. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1180-85.
Progesterone. Lodi, Italy: IBSA Farmaceutici Italia Srl; 2013. [Accessed 21 Jun. 2019] (online) Available from:
Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 03 Apr. 2019] (online) Available from:
Progesterone [Product Description]. Corona, CA: Watson Laboratories, Inc.; 2007. [Accessed 28 Mar. 2023] (online) Available from:
Medroxyprogesterone acetate. Sandton, South Africa: Pfizer Laboratories (Pty) Ltd.; 2025. [Accessed 02 March. 2025] (online) Available from:

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Walter Bushnell
Address: Walter Bushnell, Unit No. 6, LSC, S-Block, Panchsheel Park, New Delhi – 110017

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Microgest 50mg Injection

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Microgest Injection

Benefits of Microgest Injection

Side effects of Microgest Injection

How to use Microgest Injection

How Microgest Injection works

All substitutes for Microgest 50mg Injection

Aqsusten 50 Injection

Aquagest 50mg Injection

Seacure-AQ 50mg Injection

C Hop AQ 50mg Injection

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Tamoxifen (Oral Route)

Letrozole (Oral Route)

Lorlatinib (Oral Route)

Anastrozole (Oral Route)

Darunavir (Oral Route)

Frequently asked questions

What is Microgest 50mg Injection?

What does Microgest 50mg Injection treat?

How and in what dose should I take Microgest 50mg Injection?

Does Microgest 50mg Injection cause weight gain?

How is Microgest 50mg Injection beneficial for fertility and pregnancy?

Is Microgest 50mg Injection effective?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Anti Mullerian Hormone

Glycosylated Hemoglobin

Testosterone Total

Thyroid Stimulating Hormone

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

Related/Popular tests