Metsmall 500 Tablet SR

Metformin (500mg)

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Metsmall 500 Tablet SR is a medicine used to treat type 2 diabetes mellitus. It helps control blood sugar levels and thus prevents serious complications of diabetes. It is also used to treat a menstruation-related disorder known as polycystic ovary syndrome (PCOS) in women.

Written By Dr. Lipika Khurana, PGDHHM, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 14 May 2026 | 04:55 PM (IST)

₹50.1 MRP ₹56.7112% off

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Gurgaon

Available in pack-size of 30 tablet sr

30 tablet sr pack-size available

Metsmall 500 Tablet SR

₹58.7~~₹64.38~~

Available in pack size of 30 tablet sr

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Metsmall 500 Tablet SR

strip of 28 tablet sr

₹50.1

~~₹56.71~~

Different pack-size

Metsmall 500 Tablet SR

strip of 30 tablet sr

Metformin (500mg)

by Dr Reddy's Laboratories Ltd

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₹58.7

₹1.96 per unit

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General Information

Contains

Metformin (500mg)

Marketer

Dr Reddy's Laboratories Ltd

Storage

Store below 25°C

The content is shown in English

Product introduction

Metsmall 500 Tablet SR are relatively smaller and lighter than regular metformin tablets, making them easier to swallow. This helps with treatment adherence, improves overall diabetes management, and health outcomes.

Metsmall 500 Tablet SR is best taken with food; this would prevent nausea and abdominal pain. For maximum benefits, take it regularly and at the same time each day. Do not stop taking the medicine unless your doctor recommends it. Your lifestyle plays a big part in controlling diabetes. Therefore, it is important to stay on the diet and exercise program recommended by your doctor while taking this medicine.

The most common side effects of this medicine include diarrhea, nausea, vomiting, flatulence, weakness, indigestion, abdominal discomfort, headache, and loss of appetite. Some people may develop hypoglycemia (low blood sugar level) when this medicine is taken along with other antidiabetic medicines, alcohol, or upon skipping a meal. Monitor your blood sugar levels regularly while taking it.

Before taking Metsmall 500 Tablet SR, inform your doctor if you have any kidney, liver, or heart problems. Pregnant or breastfeeding women should also consult their doctor before taking it. Your doctor will check your kidney function tests before starting treatment with it. Avoid excessive alcohol intake while taking it as this may increase the risk of developing some side effects.

Uses of Metsmall Tablet SR

Treatment of Type 2 diabetes mellitus : In a condition where the body does not use insulin properly or does not produce enough insulin, this medicine helps lower blood sugar levels. It is used along with diet and exercise in adults to improve blood sugar control and reduce symptoms such as increased thirst, frequent urination, and tiredness.

Benefits of Metsmall Tablet SR

Treatment of Type 2 diabetes mellitus
Lowering blood glucose levels is an essential part of managing diabetes. If you can control the level, you will reduce the risk of getting any of the serious complications of diabetes, such as kidney damage, eye damage, nerve problems, and loss of limbs. Taking Metsmall 500 Tablet SR regularly, along with proper diet and exercise, will help you live a normal, healthy life.

Side effects of Metsmall Tablet SR

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Metsmall

Diarrhea
Headache
Vomiting
Nausea
Abdominal discomfort

How to use Metsmall Tablet SR

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Metsmall 500 Tablet SR should be taken with or after food.

How Metsmall Tablet SR works

Metsmall 500 Tablet SR works by lowering the excess glucose made by the liver and reducing the amount of glucose absorbed from food in the intestines. It also improves insulin sensitivity, which helps the body use insulin more effectively to move glucose from the blood into the cells for energy. This helps keep blood sugar levels under better control in people with type 2 diabetes mellitus.

All substitutes for Metsmall 500 Tablet SR

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

The chances of weight gain and low blood sugar are lower with this medicine as compared to other diabetes medicines.
Hypoglycemia (low blood sugar level) may occur when taken along with other antidiabetic medicines or alcohol, or on delaying/skipping a meal. Carry a sugar source with you for immediate relief.
Tell your doctor immediately if you experience any deep or rapid breathing, persistent nausea, vomiting, and stomach pain, as Metsmall 500 Tablet SR may cause a rare but serious condition called lactic acidosis, which is an excess of lactic acid in the blood.
Prolonged use of Metsmall 500 Tablet SR may lead to vitamin B12 deficiency, which may lead to anemia, causing fatigue, pale skin, shortness of breath, or headache. Notify your doctor if you experience any of these, as you may require supplements.
Your doctor will monitor your blood sugar levels and kidney function regularly while you are taking this medication.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Metsmall 500 Tablet SR

Pregnancy

SAFE IF PRESCRIBED

Metsmall 500 Tablet SR is safe to use during pregnancy. Most studies have shown low or no risk to the developing baby.

Breast feeding

SAFE IF PRESCRIBED

Metsmall 500 Tablet SR may be safe to use during breastfeeding. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

Driving

SAFE

Metsmall 500 Tablet SR does not usually affect your ability to drive.

Kidney

CAUTION

Metsmall 500 Tablet SR should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
Use of Metsmall 500 Tablet SR is, however, not recommended in patients with severe kidney disease.

Liver

SAFE IF PRESCRIBED

Metsmall 500 Tablet SR is probably safe to use in patients with liver disease. Limited data suggest dose adjustment may not be needed.

Interaction with drugs

Taking Metsmall with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Severe

Disopyramide (Oral Route)

If concurrent use is essential, watch out for symptoms such as confusion, headache, nausea, dizziness or faintness and consult your doctor if you experience them.

Moderate

Acetazolamide (Oral Route)

If concurrent use is essential, watch out for symptoms such as weakness, nausea, vomiting, abdominal pain, irregular heartbeat, fatigue or loss of appetite and consult your doctor if you experience them. They may monitor your kidney function frequently.

Moderate

Amisulpride (Oral Route)

If concurrent use is essential, your doctor may monitor your glucose levels frequently and adjust the doses as per the observations. Amisulpride may reduce the efficacy of Metformin.

Moderate

Amisulpride (Injection Route)

If concurrent use is essential, your doctor may monitor your glucose levels frequently and adjust the doses as per the observations. Amisulpride may reduce the efficacy of Metformin.

Moderate

Aripiprazole (Oral Route)

If concurrent use is essential, your doctor may monitor your glucose levels frequently and adjust the doses as per the observations. Aripiprazole may reduce the efficacy of Metformin.

Frequently asked questions

How does this medicine help in both diabetes and PCOS when these are different conditions?

In diabetes, the main issue is high blood sugar due to insulin resistance. In Polycystic Ovary Syndrome, insulin resistance also plays a key role and affects hormone balance. Metsmall 500 Tablet SR improves how the body responds to insulin, which helps lower blood sugar in diabetes and can also help regulate hormones and cycles in PCOS.

Can this medicine be used if blood sugar levels are only slightly high?

Yes, it may be prescribed even in early stages or prediabetes to improve insulin sensitivity and prevent progression, especially when lifestyle changes alone are not enough.

Do I need to continue Metsmall 500 Tablet SR long-term?

Both diabetes and PCOS are long-term conditions. Metsmall 500 Tablet SR is often used for an extended period, but the duration depends on your response, goals, and your doctor’s advice.

What makes Metsmall 500 Tablet SR different from other diabetes medicines?

Unlike some medicines that increase insulin levels, this medicine mainly works by improving how the body uses insulin and reducing sugar production in the liver, which makes it a commonly used first-line treatment.

Fact Box

Chemical Class

Biguanide derivative

Habit Forming

Therapeutic Class

ANTI DIABETIC

Action Class

Biguanides

Related lab tests

Glucose - Fasting Blood

Glucose - Postprandial Blood

Glycosylated Hemoglobin

References

Powers AC, D’Alessio D. Endocrine Pancreas and Pharmacotherapy of Diabetes Mellitus and Hypoglycemia. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. pp. 1258-60.
Nolte MS. Pancreatic hormones and antidiabetic drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 741-42.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 873-75.
Metformin hydrochloride [FDA Label]. Princeton, New Jersey: Bristol-Myers Squibb Company. [Accessed 12 Mar. 2019] (online) Available from:
Metformin hydrochloride oral solution [FDA Label]. Gloversville, New York: Ranbaxy Pharmaceuticals Inc.; 2003. [Accessed 12 Mar. 2019] (online) Available from:
Metformin [EMC Label]. Middlesex, UK: Merck Serono Ltd.; 2020. [Accessed 27 Sep. 2021]. (online) Available from:
Metformin [FDA Label]. Princeton, NJ: Bristol-Myers Squibb Company; 2017. [Accessed 26 Sept. 2021] (online) Available from:
Metformin [FDA Label]. Hyderabad: Granules India Limited; 2016. [Accessed 27 Sept. 2021]. (online) Available from:
National Health Service. Pregnancy, breastfeeding and fertility while taking metformin. [Last Reviewed: 24 Mar. 2022]. [Accessed 11 Jul. 2023]. (online) Available from:
Metformin [Summary of Product Characteristics]. Abuja, Nigeria: Bell Bag Pharmaceuticals; 2025. [Accessed 11 Jul. 2023] (online) Available from:

User feedback

Patients taking Metsmall 500 Tablet SR

Twice A Day

60%

Once A Day

40%

What are you using Metsmall Tablet SR for?

Type 2 diabetes mellitus

79%

Others

11%

Polycystic ovarian syndrome (PCOS)

10%

How much was the improvement?

Poor

39%

Average

36%

Excellent

24%

What were the side-effects while using Metsmall 500 Tablet SR?

Nausea

27%

Taste change

23%

Vomiting

23%

No Side Effect

15%

Diarrhea

12%

How do you take Metsmall Tablet SR?

With food

70%

Empty stomach

19%

With or without food

11%

Please rate Metsmall 500 Tablet SR on price

Not Expensive

48%

Average

31%

Expensive

21%

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Dr Reddy's Laboratories Ltd
Address: Dr. Reddy's Laboratories Ltd., Village Malpur, P.O.Bhud, Baddi, Dist. Solan, H.P.

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Home

Anti Diabetic

Oral Antidiabetics

Metsmall 500 Tablet SR

Metsmall 500 Tablet SR

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Metsmall Tablet SR

Benefits of Metsmall Tablet SR

Side effects of Metsmall Tablet SR

How to use Metsmall Tablet SR

How Metsmall Tablet SR works

All substitutes for Metsmall 500 Tablet SR

Metform SR 500 Tablet

Glycomet 500 SR Tablet

Glyciphage SR 500mg Tablet

GlUCOnorm SR 500mg Tablet

Bigomet SR 500 Tablet

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Disopyramide (Oral Route)

Acetazolamide (Oral Route)

Amisulpride (Oral Route)

Amisulpride (Injection Route)

Aripiprazole (Oral Route)

Frequently asked questions

How does this medicine help in both diabetes and PCOS when these are different conditions?

Can this medicine be used if blood sugar levels are only slightly high?

Do I need to continue Metsmall 500 Tablet SR long-term?

What makes Metsmall 500 Tablet SR different from other diabetes medicines?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Glucose - Fasting Blood

Glucose - Postprandial Blood

Glycosylated Hemoglobin

References

User feedback

Patients taking Metsmall 500 Tablet SR

What are you using Metsmall Tablet SR for?

How much was the improvement?

What were the side-effects while using Metsmall 500 Tablet SR?

How do you take Metsmall Tablet SR?

Please rate Metsmall 500 Tablet SR on price

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

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