Content Details
Written By
MD (Pharmacology), MBBS
Reviewed By
MD (Pharmacology), MBBS
Last updated on:
12 Aug 2019 | 11:59 AM (IST)
Want to know more?
Read Our Editorial Policy
Have issue with the content?
Report Problem

Metgem 500 Tablet ER


Overview

Introduction of Metgem Tablet ER

Metgem 500 Tablet ER is a medicine used in the treatment of type 2 diabetes mellitus. It helps to lower the high blood sugar levels and prevents long-term complications. This drug should be used along with a proper diet and regular exercise for best results. It should be taken with food to avoid the side effects of nausea and upset stomach.

Uses of Metgem Tablet ER

Metgem Tablet ER side effects

Common
  • Nausea
  • Vomiting
  • Taste change
  • Diarrhea
  • Abdominal pain
  • Loss of appetite
Severe
  • Lactic acidosis

How to use Metgem Tablet ER

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Metgem 500 Tablet ER is to be taken with food.

How Metgem Tablet ER works

Metformin is an anti-diabetic medication (biguanide). It works by lowering glucose production in the liver, delaying sugar (glucose) absorption from intestines and increasing the body's sensitivity to insulin.

Metgem Tablet ER related warnings

Alcohol
CAUTION
It is unsafe to consume alcohol with Metgem 500 Tablet ER. Taking metformin with alcohol can cause lactic acidosis and you may experience malaise, respiratory distress, slow or irregular heartbeat, sleepiness, stomach upset, or other unusual symptoms.
Pregnancy
PROBABLY SAFE
Metgem 500 Tablet ER is probably safe to use during pregnancy.
Animal studies have shown low or no adverse effect on the fetus, however, there are limited human studies. Please consult your doctor.
Lactation
Metgem 500 Tablet ER is probably safe to use during lactation. Limited human data suggests that the drug does not represent a significant risk to the baby.
Driving
Your ability to drive may be affected if your blood sugar is low or high. If this happens, do not drive.
Kidney
CAUTION
Metgem 500 Tablet ER should be used with caution in patients with kidney disease. Dose adjustment of Metgem 500 Tablet ER may be needed. Please consult your doctor.
Use of Metgem 500 Tablet ER is, however, not recommended in patients with severe kidney disease. Regular monitoring of kidney function test is advisable while you are taking this medicine.
Liver
CAUTION
Metgem 500 Tablet ER should be used with caution in patients with liver disease. Dose adjustment of Metgem 500 Tablet ER may be needed. Please consult your doctor.
Metgem 500 Tablet ER is generally started with low dose in patients with mild to moderate liver disease and its use is not recommended in patients with severe liver disease.

What if you miss a dose of Metgem Tablet ER?

If you miss a dose of Metgem 500 Tablet ER, skip it and continue with your normal schedule. Do not double the dose.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Metgem 500 Tablet ER
₹2.08/Tablet ER
₹1.88/Tablet ER
save 10%
MET-SR 500 Tablet
West-Coast Pharmaceutical Works Ltd
₹1.8/Tablet ER
save 13%
₹2.9/Tablet ER
39% costlier
Ozomet 500 Tablet ER
Ozone Pharmaceuticals Ltd
₹1.74/Tablet ER
save 16%
Ozomet 500 Tablet ER
Ozone Pharmaceuticals Ltd
₹1.67/Tablet ER
save 20%

Expert Advice

  • Chances of weight gain and low blood sugar are lesser as compared to other diabetes medicines. 
  • Hypoglycemia (low blood sugar level) may occur when taken along with other antidiabetic medicines, alcohol or on delaying/skipping a meal. Carry a sugar source with you for immediate relief.
  • Tell your doctor immediately if you experience any deep or rapid breathing, persistent nausea, vomiting, and stomach pain as Metgem 500 Tablet ER may cause a rare but serious condition called lactic acidosis, which is an excess of lactic acid in the blood.
  • Vitamin B12 deficiency and symptoms of anemia like fatigue, pale skin, shortness of breath or headache may occur. Notify your doctor if you experience any of these as you may require supplements.
  • Your doctor will monitor your blood sugar levels and kidney functions regularly while taking this medication.

Interaction with Drugs

Taking Metgem with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Defmark, Zacdef, Ecodef
SERIOUS
Brand(s): Digeplex T
SERIOUS
Brand(s): Kopram, Ecit, Escnx
SERIOUS
Brand(s): Zencort-M, Welone
SERIOUS
Brand(s): Psycool, Proparise
SERIOUS
Brand(s): Nudiglue-C
SERIOUS
Brand(s): Densol
SERIOUS
Brand(s): Leparox, Prx
SERIOUS
Brand(s): Acigo, Rin, Ranis
SERIOUS

Patient Concerns

Questions Related to Metgem

arrow
Ayurvedic treatment for type 2 diabetesI am already on metformin 500 mg
Dr. Aanchal Maheshwari
Ayurveda
Depend upon , the value of blood sugar
Type 2 diabetes taking glyciphage 500 one time daily and high bp avg 140/100 taking olmat 20 once
Dr. Deepak Kumar Soni
Skin Specialist
https://www.1mg.com/otc/bgr-34-tablet-otc3226311-1 Tablet after lunch & dinner, Take at least 1-2 months.take this medicine along with your treatment
arrow
Do you have any questions related to Metgem 500 Tablet ER?

User Feedback


FAQs

Q. Does Metgem clear acne?

Metgem is not indicated specifically to clear acne. However, in women with polycystic ovarian syndrome (PCOS), it helps clear acne along with other problems like facial hair, abdominal obesity, and irregular menstruation.

Q. Can I take Metgem forever?

Metgem is generally a safe and well-tolerated drug even on long-term use. However, it should be used for the duration prescribed by your doctor.

Q. Does Metgem cause weight gain?

No, weight gain has not been reported with Metgem. Rather, it helps in decreasing weight especially in abdominal fat patients of type 2 diabetes mellitus. In women with polycystic ovarian syndrome (PCOS), it helps in losing weight along with relieving other problems like facial hair, acne, and irregular menstruation.

Q. Can the use of Metgem cause vitamin B12 deficiency?

Yes, long-term use of Metgem can cause vitamin B12 deficiency. long-term use interferes with the absorption of vitamin B12 in the stomach. If untreated, it may cause anemia and nerve problems and the patient can have tingling sensation and numbness in hands and feet, weakness, urinary problems, change in mental status and difficulty in making balance (ataxia). To avoid these problems, doctors usually suggest an intake of vitamin B12 from outside at least once every year.

Q. Is Metgem helpful in patients with polycystic ovarian syndrome (PCOS)?

Yes. Metgem is used off-label in the treatment of PCOS. It may be used along with other medicines to induce ovulation and regularize menstrual cycles.

Q. How does Metgem help in weight loss?

Metgem helps in weight loss by decreasing the hunger (appetite), and hence, the food intake. It makes the insulin already available in your body to work more effectively. This leads to a decrease in glucose production, increase the glucose use and decrease the fat deposits which further helps to lower the body weight.

Q. Does Metgem cause bloating?

Yes, the use of Metgem can cause bloating. To minimize this side effect, it is advised to take it after your meals.

Q. Is Metgem useful in the treatment of infertility?

Metgem is prescribed to improve the insulin resistance in the body. Proper insulin resistance regulates ovulation, maintains proper androgen levels in the body, and improves menstrual regularity. This increases the pregnancy rates and outcomes and indirectly treats the infertility associated with polycystic ovary syndrome (PCOS).

Q. Is Metgem useful in the treatment of prediabetes?

Metgem is seen to be useful in the management of prediabetes, a condition with blood glucose levels higher than normal but not high enough to label you as diabetic. Metgem makes the insulin already available in your body to work more effectively, decreases glucose production by liver and increases use of glucose by the muscles and lowers body weight. However, lifestyle modifications like a change in diet and exercise should be tried first as they are seen to be more effective than Metgem.

Q. Does Metgem cause blurry vision?

Metgem is not known to cause blurred vision. Change in vision in a patient with diabetes could be due to multiple reasons. Please consult your doctor if blurred vision occurs.

Q. Does Metgem use leads to anemia?

Metgem may decrease the levels of vitamin B12 on long term use which may rarely cause a type of anemia in which blood cells are larger than normal (megaloblastic anemia). You may need to take foods rich in vitamin B12 like eggs, dairy products, and meat or a supplement from outside.

Q. How beneficial is it to take Metgem with linagliptin?

Both Metgem and linagliptin are anti-diabetic drugs and can be used together. Their fixed dose combinations are also available and commonly advised once Metgem is unable to control blood sugar levels even after giving the maximum tolerated dose. As they work by different mechanisms, they help in better control of blood sugar levels compared to either drug taken alone.

Related Products

Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
  1. Powers AC, D’Alessio D. Endocrine Pancreas and Pharmacotherapy of Diabetes Mellitus and Hypoglycemia. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. pp. 1258-60.
  2. Nolte MS. Pancreatic hormones and antidiabetic drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 741-42.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 873-75.
  4. Metformin hydrochloride. Princeton, New Jersey: Bristol-Myers Squibb Company. [Accessed 12 Mar. 2019] (online) Available from:External Link
  5. Metformin hydrochloride oral solution. Gloversville, New York: Ranbaxy Pharmaceuticals Inc.; 2003. [Accessed 12 Mar. 2019] (online) Available from:External Link
  6. Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-98. [Accessed 12 Mar. 2019] (online) Available from:External Link
Manufacturer/Marketer Address
90, Delhi - Jaipur Road, Sector 32, Gurugram, Haryana 122001
A licensed pharmacy from your nearest location will deliver Metgem 500 Tablet ER. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your prescription and the availability of this medicine.
Best Price
₹16.67
MRP20.84  Get 20% OFF
This price is valid only on the orders above ₹500
10 tablet er in 1 strip
ADD TO CART
Additional offers
Amazon Pay: Win up to ₹200 on minimum order value of ₹100 | Valid once per user from 1 August to 31 August
Show more show_more

INDIA’S LARGEST HEALTHCARE PLATFORM

150M+
Visitors
25M+
Orders Delivered
1000+
Cities
Get the link to download App
+91
Reliable

All products displayed on 1mg are 100% genuine and all labs listed on the platform are accredited

Secure

1mg uses Secure Sockets Layer (SSL) 128-bit encryption and is Payment Card Industry Data Security Standard (PCI DSS) compliant

Affordable

Enjoy 20% off on allopathy medicines, up to 50% off on health products, up to 80% off on lab tests and free doctor consultations

India's only LegitScript and ISO/IEC 27001 certified online healthcare platform
Know More About 1mg
Access medical and health information

1mg provides you with medical information which is curated, written and verified by experts, accurate and trustworthy. Our experts create high-quality content about medicines, diseases, lab investigations, Over-The-Counter (OTC) health products, Ayurvedic herbs/ingredients, and alternative remedies.

Order medicines online

Get free medicine home delivery in over 1000 cities across India. You can also order Ayurvedic, Homeopathic and other Over-The-Counter (OTC) health products. Your safety is our top priority. All products displayed on 1mg are 100% genuine.

Book lab tests

Book any lab tests and preventive health packages from certified labs and get tested from the comfort of your home. Enjoy free home sample collection, view reports online and consult a doctor online for free.

Consult a doctor online

Got a health query? Consult doctors online from the comfort of your home for free. Chat privately with our registered medical specialists to connect directly with verified doctors. Your privacy is guaranteed.