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Metanorm 500 mg Tablet SR

Elder Pharmaceuticals Ltd

Composition for Metanorm 500 mg Tablet SR

Prescription Required

Primary uses of Metanorm 500 mg Tablet SR

Potentiallyunsafewith
Alcohol
MRP
17.41
₹1.74/Tablet SR
10 tablet sr in 1 strip
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Medicine Overview of Metanorm Tablet SR

Uses of Metanorm Tablet SR

Metanorm 500 mg Tablet SR is used in the treatment of type 2 diabetes. It is used in addition to diet and exercise to improve blood sugar control in adults with type 2 diabetes.

Metanorm Tablet SR side effects

Common

Side Effects of Metanorm are Nausea, Vomiting, Taste change, Diarrhoea, Abdominal pain, Loss of appetite.

How to use Metanorm Tablet SR

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Metanorm 500 mg Tablet SR is to be taken with food.

How Metanorm Tablet SR works

Metformin is an anti-diabetic medication (biguanide). It works by lowering glucose production in the liver, delaying sugar (glucose) absorption from intestines and increasing the body's sensitivity to insulin.

In Depth Information on Metanorm Tablet SR

Expert advice for Metanorm Tablet SR

  • Your doctor will monitor your blood sugar levels and kidney functions regularly while taking this medication.
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Metanorm Tablet SR related warnings
Special precautions for Metanorm Tablet SR
Alcohol
CAUTION
Taking metformin with alcohol can cause lactic acidosis and you may experience malaise, respiratory distress, slow or irregular heartbeat, sleepiness, stomach upset, or other unusual symptoms.
Pregnancy
PROBABLY SAFE
Metanorm 500 mg Tablet SR is probably safe to use during pregnancy.
Animal studies have shown low or no adverse effect on the foetus, however, there are limited human studies. Please consult your doctor.
Lactation
Metanorm 500 mg Tablet SR is probably safe to use during lactation. Limited human data suggests that the drug does not represent a significant risk to the baby.
Driving
Your ability to drive may be affected if your blood sugar is low or high. If this happens, do not drive.
Kidney
CAUTION
Metanorm 500 mg Tablet SR should be used with caution in patients with kidney disease. Dose adjustment of Metanorm 500 mg Tablet SR may be needed. Please consult your doctor.
Use of Metanorm 500 mg Tablet SR is, however, not recommended in patients with severe kidney disease. Regular monitoring of kidney function test is advisable while you are taking this medicine.
Liver
CAUTION
Metanorm 500 mg Tablet SR should be used with caution in patients with liver disease. Dose adjustment of Metanorm 500 mg Tablet SR may be needed. Please consult your doctor.
Metanorm 500 mg Tablet SR is generally started with low dose in patients with mild to moderate liver disease and its use is not recommended in patients with severe liver disease.

What if you miss a dose of Metanorm Tablet SR?uses

If you miss a dose of Metanorm 500 mg Tablet SR, skip it and continue with your normal schedule. Do not double the dose.

Patient Concerns

Frequently asked questions about Metanorm Tablet SR

Frequently asked questions about Metformin

Q. Is Metanorm helpful in patients with polycystic ovarian syndrome (PCOS)?
Yes. Metanorm is helpful in patients with PCOS. It may be used along with other medicines to induce ovulation and regularize menstrual cycles. It also delays the development of type 2 diabetes if you already have prediabetes and aids in weight loss if you follow a diet and exercise program.
Q. How does Metanorm help in weight loss?
Metanorm helps in weight loss by decreasing hunger (appetite) and hence food intake. It makes the insulin already available in your body to work more effectively. This leads to decrease glucose production, increase glucose use and decreased fat deposits which further helps to lower body weight. However, it is not yet approved for weight loss, this is an off-label use.
Q. Is Metanorm useful in the treatment of infertility?
Metanorm is commonly used off-label for the treatment of infertility associated with polycystic ovary syndrome (PCOS). It regulates ovulation and androgen levels in the body and improves menstrual regularity and pregnancy rates and outcomes. This beneficial effect is thought to be due to improvement in insulin resistance by Metanorm.
Q. Does Metanorm cause low blood sugar levels (hypoglycemia)?
Metanorm can lower blood sugar level (hypoglycemia). It happens more often if you delay or miss your food, do more than your routine exercise, drink alcohol or take other antidiabetic medicine along with. So, regular monitoring of blood sugar level is important and be cautious of symptoms of hypoglycemia and always keep glucose tablets, honey or fruit juice with you.
Q. Can I take Metanorm forever?
Metanorm is generally a safe and well-tolerated drug even on long-term use. However, its long-term use can cause vitamin B12 deficiency leading to anemia and peripheral neuropathy (nerve damage). so, it should be taken only at prescribed doses for the duration as advised by the doctor.
Q. Is Metanorm a sulfonylurea?
No, Metanorm is not a sulfonylurea. It is an antidiabetic drug used to control high blood sugar levels in newly-diagnosed type 2 diabetes patients, along with modification in diet and exercise.
Q. Is Metanorm a steroid?
No, Metanorm is not a steroid. It is an antidiabetic drug used to control high blood sugar levels in newly-diagnosed type 2 diabetes patients, along with modifications in diet and exercise.
Q. Does Metanorm cause bloating?
Metanorm commonly causes stomach upset like bloating (heavy and uncomfortable feeling in the stomach), nausea, vomiting, and diarrhea. To avoid these side effects, it is advised to be taken after meals, preferably started at a low dose and then increased slowly over weeks, or by using slow-release tablets.
Q. Is Metanorm good for fatty liver?
Metanorm is seen to be beneficial in the treatment of non-alcoholic fatty liver disease (NAFLD). One of the underlying cause of NAFLD is insulin resistance. Metanorm improves insulin resistance and liver enzymes in these patients. It is not seen to benefit patients of alcoholic fatty liver disease and is usually avoided in patients with liver cirrhosis as they are at an increased risk of lactic acidosis.
Q. What is the benefit of combining Metanorm with coenzyme q10?
Coenzyme Q10 is an antioxidant that helps in energy production and is found in heart, liver, kidney, and pancreas (which produces insulin). It can repair the damage caused to these organs by free radicals. Low levels of CoQ10 are seen in patients with diabetes. So, some researchers suggest it be given from outside. It can be taken with Metanorm as no drug-drug interactions or harmful effects have been seen between the two.
Q. Does Metanorm help in improving your menstrual cycle (periods)?
Yes, Metanorm does improve menstrual cycle (periods) regularity in women with polycystic ovarian syndrome (PCOS). It is associated with insulin resistance, decreased ovulation, and high androgen levels which cause menstrual irregularities like delayed periods and scanty bleeding. Metanorm helps in regularizing menstrual cycles by improving insulin sensitivity, ovulation rate, and decreasing androgen levels.
Q. Can I take Metanorm with atorvastatin?
Yes, Metanorm can be taken with atorvastatin. There are no reported harmful effects when they are used together. Rather some studies suggest beneficial effects in diabetics as they may prevent a very high increase in blood glucose after food, decrease some inflammation markers and protect the patients from liver injury.
Q. Can I take Metanorm with phentermine?
Metanorm can be taken with phentermine. These are sometimes given together in obese patients who are also diabetic and are taking Metanorm along with exercise and diet modification. Phentermine decreases food intake by its action in the brain. However, phentermine can decrease the effect of Metanorm leading to very high blood glucose levels. So, a dose adjustment of Metanorm may be needed.
Q. Can I take Metanorm with levothyroxine?
Metanorm can be taken with levothyroxine but the dose of Metanorm may need to be adjusted. Levothyroxine can decrease the effect of Metanorm leading to very high blood glucose levels. These are used together in patients with coexisting thyroid disease and diabetes mellitus or polycystic ovarian syndrome (PCOS).
Q. Can I take Metanorm with prednisolone?
Metanorm can be taken with prednisolone but the dose of Metanorm may need to be adjusted. Prednisolone can decrease the effect of Metanorm leading to very high blood glucose levels. Continuous use of steroids like prednisolone can also cause diabetes known as glucocorticoid-induced diabetes and use of Metanorm is recommended in these patients.
Q. Can I take Metanorm with metoprolol?
Metanorm can be taken with metoprolol. There are no reported drug interactions or harmful effects in humans when they are used together. However, some animal studies suggest that metoprolol can decrease the blood levels of Metanorm and on long-term use can increase lactic acid and uric acid levels.
Q. Does Metanorm clear acne?
Metanorm is not indicated for clearing acne due to just any condition. It only helps in clearing acne in women with polycystic ovarian syndrome (PCOS) along with other problems like facial hair, abdominal obesity, and irregular menstruation.
Q. Does Metanorm cause hair loss?
No, hair loss has not been reported with Metanorm. It only helps in clearing facial hair (hirsutism) in women with polycystic ovarian syndrome (PCOS) along with other problems like acne, abdominal obesity, and irregular menstruation.
Q. Does Metanorm cause weight gain?
No, weight gain has not been reported with Metanorm. Rather it helps in decreasing weight especially abdominal fat patients of type 2 diabetes mellitus and in women with polycystic ovarian syndrome (PCOS) along with other problems like facial hair, acne, and irregular menstruation.
Q. Does Metanorm cause constipation?
Metanorm is not known to cause constipation. Some common side effects associated with the use of Metanorm includes nausea, vomiting, abdominal pain, altered taste, diarrhea, and loss of appetite.
Q. Is Metanorm safe?
Metanorm is a safe and well-tolerated drug even on long-term use when taken strictly as advised by the doctor. However, there are some very common side effects like nausea, vomiting, abdominal pain, altered taste, diarrhea, and loss of appetite you may experience even at therapeutic doses.
Q. Does Metanorm increase blood pressure?
Metanorm is not known to increase blood pressure. Some common side effects associated with the use of Metanorm includes nausea, vomiting, abdominal pain, altered taste, diarrhea, and loss of appetite.
Q. Is Metanorm an insulin?
No, Metanorm is not an insulin. Metanorm is an oral drug used in type 2 diabetes mellitus and lowers blood glucose levels by decreasing its production and increasing absorption and making the already available insulin in your body to work better. Insulin is a normally produced hormone in the body, used in the injectable form in the treatment of both type 1 and 2 diabetes mellitus and it works by absorbing and storing glucose from the blood.
Q. Is Metanorm a banned drug?
No, Metanorm is not a banned drug. It is a prescription medicine and is available when prescribed by registered medical practitioner.
Q. Is Metanorm a birth control pill?
No, Metanorm is not a birth control pill. It is an antidiabetic drug used to control high blood sugar levels in newly-diagnosed type 2 diabetes patients, along with modification in diet and exercise.
Q. Is Metanorm a statin?
No, Metanorm is not a statin. It is an antidiabetic drug used to control high blood sugar levels in newly-diagnosed type 2 diabetes patients, along with modification in diet and exercise.
Q. Can I take Metanorm with saxagliptin?
Both Metanorm and saxagliptin are anti diabetic drugs and can be used together. Their fixed dose combinations are also available and commonly advised once Metanorm is unable to control blood sugar levels even after giving the maximum tolerated dose. As they work by different mechanisms, they help in better control of blood sugar levels compared to either drug taken alone.
Q. Does Metanorm cause blurry vision?
Metanorm is not known to cause blurred vision. Change in vision in a patient with diabetes could be due to multiple reasons. It could be a temporary problem either due to high blood sugar levels which cause your lens inside your eye to swell and change your vision. If the blurred vision continues for a long time, consult a doctor.
Q. What is lactic acidosis and how is it related to Metanorm use?
Lactic acidosis is a rare, but serious complication associated with the use of Metanorm. Patient has high blood lactic acid levels and may present with tiredness, weakness, stomach pain, loose stools, severe muscle pain, muscle cramps and difficulty in breathing. It is especially seen in old age patients, those with kidney, liver or heart disease, or who take large amounts of alcohol. If you have these symptoms, stop taking Metanorm and consult your doctor.
Q. Is Metanorm use associated with liver pain?
Metanorm is not known to cause any liver pain or damage. Rather, it is seen to be useful in patients with non-alcoholic fatty liver disease (NAFLD) and chronic hepatitis C. However, it is usually avoided in patients with liver cirrhosis as they are at an increased risk of lactic acidosis which is a serious complication associated with the use of Metanorm.
Q. Does Metanorm make you feel high?
No, Metanorm does not elevate the mood or make you feel high. It is an antidiabetic drug used to control high blood sugar levels in newly-diagnosed type 2 diabetes patients, along with modification in diet and exercise. Rare side effects of Metanorm include anxiety and depression.
Q. Can Metanorm cause back pain?
Usually, Metanorm is not associated with back pain. However, it can be a presentation of stomach upset, a common side effect caused by Metanorm which includes bloating (heavy and uncomfortable feeling in the stomach), nausea, vomiting, and diarrhea, or it could be a symptom of lactic acidosis, a rare and a serious complication of Metanorm.
Q. Can long-term use of Metanorm cause vitamin b12 deficiency?
Yes, Metanorm causes vitamin B12 deficiency on long-term use as it interferes with absorption of vitamin B12 in the stomach. If untreated, it may cause anemia and nerve problems and the patient can have tingling sensation and numbness in hands and feet, weakness, urinary problems, change in mental status and difficulty in making balance (ataxia). To avoid these problems, some researchers suggest an intake of vitamin B12 from outside at least once every year.
Q. Is Metanorm useful in the management of metabolic syndrome?
Yes, Metanorm is seen to be useful in the management of metabolic syndrome, a collection of risk factors that include high blood pressure, high blood sugar levels, abnormal blood cholesterol levels and excess fat around the waist. Metanorm is an insulin sensitizer and it improves the action of insulin and normalises blood sugar levels and reduces body weight.
Q. How beneficial is it to take Metanorm with glimepiride?
Both Metanorm and glimepiride are anti diabetic drugs and can be used together. They work by different mechanisms and can control the blood sugar levels in a much better way when used together as compared to either drug taken alone. However, glimepiride can cause very low blood glucose levels, so a regular monitoring of blood glucose is very important.
Q. Is it safe to take Metanorm with cetirizine?
Yes, Metanorm can be taken with cetirizine. There are no reported drug interactions or harmful effects when they are used together.
Q. Can I take Metanorm and ranitidine together?
Metanorm can be taken with ranitidine. However, if you are taking them together, you need to monitor blood glucose levels regularly as ranitidine can decrease the removal of Metanorm from the body and increase its blood levels. This can cause very low blood sugar levels and other side effects as well and the dose of Metanorm may need adjustment.
Q. How beneficial is it to take Metanorm with linagliptin?
Both Metanorm and linagliptin are anti-diabetic drugs and can be used together. Their fixed dose combinations are also available and commonly advised once Metanorm is unable to control blood sugar levels even after giving the maximum tolerated dose. As they work by different mechanisms, they help in better control of blood sugar levels compared to either drug taken alone.
Q. Does Metanorm inhibit hepatitis B virus protein?
Yes, some research studies have shown that Metanorm can decrease the multiplication and growth of hepatitis B virus when given along with other antiviral drugs. However, this is indication is still under research and not yet approved.
Q. Can I take Metanorm before or after a chest x-ray? Does its use lead to chest x-ray abnormality?
Metanorm should be temporarily discontinued before chest or any X-ray that requires injection of a contrast medium or dye. These dyes can decrease kidney function and Metanorm along with these dyes can cause a serious side effect like lactic acidosis. So you may need to stop taking Metanorm. However, do not stop taking any medicine without talking to your doctor.
Q. Does Metanorm make you sleepy?
Metanorm can cause sleepiness which could be an early symptom of lactic acidosis along with tiredness, weakness, stomach pain, loose stools, severe muscle pain, muscle cramps and difficulty in breathing. It is a serious condition caused by Metanorm seen in old age patients, those with kidney, liver or heart disease, or those who take large amounts of alcohol. If you have these symptoms, stop taking Metanorm and consult your doctor.
Q. Does the use of Metanorm cause joint pain?
Use of Metanorm is not associated with joint pain. However, diabetes itself decreases blood circulation to the joints and even damages them leading to joint pain. Use of anti-diabetic drugs like sitagliptin or saxagliptin is also associated with joint pain. Early symptoms of lactic acidosis like muscle pain and cramps with weakness and tiredness can be mistaken for joint pain.
Q. Can Metanorm help in reducing weight gain caused by antipsychotics?
Metanorm may be of help in the treatment and prevention of weight gain caused by antipsychotics along with lifestyle modifications like a change in diet and regular exercise. Weight gain is an important reason for discontinuation of these medicines. Metanorm improves insulin sensitivity and prevents weight gain, both of these factors are affected by the use of antipsychotics.
Q. Is Metanorm useful in the treatment of fragile X syndrome?
Metanorm has shown promising results in some animal research studies in the treatment of fragile X syndrome. It may help in improving mental and behavioral disorders (autism) and control obesity and risk of developing diabetes in these patients. But these results are very preliminary and it is still not approved for the treatment of fragile X syndrome.
Q. What is the difference between liraglutide and Metanorm?
Metanorm and liraglutide are antidiabetic drugs and both control blood sugar levels effectively. Metanorm is taken by oral route and it decreases glucose production from liver and glucose absorption from the gut and increases insulin sensitivity. While liraglutide is an injectable and it increases insulin release from the pancreas. Both cause stomach upset, like nausea, vomiting, diarrhea and bloating while liraglutide also increases the risk of pancreatitis.
Q. Does Metanorm use make you feel high?
No, Metanorm does not elevate the mood or make you feel high. It is an antidiabetic drug used to control high blood sugar levels in newly-diagnosed type 2 diabetes patients, along with modification in diet and exercise. Rare side effects of Metanorm include anxiety and depression.
Q. Does Metanorm make you sweat?
Yes, sweating is one of the known side effects of Metanorm. The exact cause of this is not known. Some researchers suggest it to be due to low blood sugar levels especially at night which can cause night sweats as well. Monitor your blood sugar levels regularly and talk to your doctor as your dose of Metanorm may need to be adjusted.
Q. Can I take Metanorm with clomiphene citrate?
Metanorm can be taken with clomiphene citrate. They are advised together in patients with infertility along with polycystic ovarian syndrome (PCOS). Clinical studies have shown an improvement in ovulation and pregnancy rates in these patients as compared to use of clomiphene citrate alone or if the patients are resistant to the effects of clomiphene citrate. However, this is still under research.
Q. Is Metanorm useful in treating or preventing breast cancer?
Metanorm is seen to be useful in the treatment and prevention of cancers especially breast cancer in research studies. As high insulin levels are known to increase the risk of cancer, Metanorm decreases cancer cell growth by decreasing insulin and blood glucose levels. However, its use in treating breast cancer is not yet approved.
Q. Does Metanorm use increase your chance to get Helicobacter pylori infection?
No, Metanorm is not associated with an increased risk of Helicobacter pylori infection. Diabetes itself increases the risk of H.pylori infection which increases the chances of stomach upset like nausea, vomiting, diarrhea, and bloating by Metanorm.
Q. Does Metanorm use leads to anemia?
Metanorm may decrease the levels of vitamin B12 on long term use which may rarely cause a type of anemia in which blood cells are larger than normal (megaloblastic anemia). You may need to take foods rich in vitamin B12 like eggs, dairy products, and meat or a supplement from outside.
Q. Is Metanorm useful in the treatment of prediabetes?
Metanorm is seen to be useful in the management of prediabetes, a condition with blood glucose levels higher than normal but not high enough to label you as diabetic. Metanorm makes the insulin already available in your body to work more effectively, decreases glucose production by liver and increases use of glucose by the muscles and lowers body weight. However, lifestyle modifications like a change in diet and exercise should be tried first as they are seen to be more effective than Metanorm.
Q. Can I take Metanorm with teneligliptin?
Yes, Metanorm can be taken with teneligliptin. It is a good add-on treatment if the blood sugars are very high even after taking Metanorm. The risk of low blood sugar levels (hypoglycemia) is also very low with both the medicines. However, consult your doctor before taking them together as a dose adjustment may be needed.

Severely interacts with other drugs like

Taking Metanorm with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Metanorm with Ketotifen
LIFE-THREATENING
Medicines with composition Ketotifen: Ketorid, Ketasma, Asthafen, Azofen, Ketovent
Metanorm with Hydrochlorothiazide
SERIOUS
Medicines with composition Hydrochlorothiazide: Hyros, Bpzide, Dizide, Xenia, Aquazide, Hydrazide, Thiazide, Hydride
Metanorm with Lactase
SERIOUS
Medicines with composition Lactase: Cry NO
Metanorm with Pindolol
SERIOUS
Medicines with composition Pindolol: Visken
Metanorm with Citalopram
SERIOUS
Medicines with composition Citalopram: Vocita, Olarc, Citopam, Cetadep, Cita, Topdep, Celica, Citalomine, Citalent, Citola, Cytop, Madam
SERIOUS
Medicines with composition Nicotinic acid / Niacin: Nicoglow
Metanorm with Paroxetine
SERIOUS
Metanorm with Triamcinolone
SERIOUS
Medicines with composition Triamcinolone: Darcort, Trilone, Mycort, Trilon, Stancort, Oraways, Triroid, Acort, Pericort, Comcort
Metanorm with Chlorthalidone
SERIOUS
Medicines with composition Chlorthalidone: Chlornol, Thiovas, Chlorfid, Lupiclor, Klorzid, Clovet, Thaloric, Thiaklor, Zione
Metanorm with Glucosamine
SERIOUS
Metanorm with Clobetasol
SERIOUS
Medicines with composition Clobetasol: Clobex
Metanorm with Rasagiline
SERIOUS
Medicines with composition Rasagiline: Rasalect, Relgin
Metanorm with Pancreatin
SERIOUS
Medicines with composition Pancreatin: Digeplex T, Enzabil, Enzelo, Aflate N, Panstal N, Panzynorm-HS, Farizyme, Lapin, Enzox, Panzynorm N
Metanorm with Spironolactone
SERIOUS
Medicines with composition Spironolactone: Aldactone, Spilactone
Metanorm with Famotidine
SERIOUS
Metanorm with Beclometasone
SERIOUS
Medicines with composition Beclometasone: Beclate
Metanorm with Collagen Peptide
SERIOUS
Medicines with composition Collagen Peptide: Nudiglue-C
Metanorm with Dapoxetine
SERIOUS
Medicines with composition Dapoxetine: Actinex, DA Sutra, Stay Tal, Dapoxy, Dapnex, Duraject, Appynite, Dejac
Metanorm with Octreotide acetate
SERIOUS
Medicines with composition Octreotide acetate: Octotide, Octride, Sandostatin LAR, Octate, Varioct, Actide, Otide, Ferotide, Sandostatin
Metanorm with Lafutidine
SERIOUS
Medicines with composition Lafutidine: Lafter, Lafudac, Lafty, Lafukem, Lafaxid, Laciloc, Lafumac, Swiftin
Metanorm with Loteprednol etabonate
SERIOUS
Medicines with composition Loteprednol etabonate: Lotesol, Lotechek, Lotepred, Prednol LS, Lotenase
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Substitutes for Metanorm Tablet SR

₹2/Tablet SR
15% costlier
Glyciphage 500mg Tablet SR
Franco-Indian Pharmaceuticals Pvt Ltd
₹2/Tablet SR
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₹1.98/Tablet SR
14% costlier
₹2/Tablet SR
15% costlier
₹2/Tablet SR
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