Mesaclear-OD Tablet PR

Mesalazine (1200mg)

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Mesaclear-OD Tablet PR is an anti-inflammatory medicine used to treat a type of bowel disease known as ulcerative colitis. It helps to reduce symptoms such as diarrhea, bleeding and stomach pain by reducing inflammation in the bowel.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Lalit Kanodia, MBA, MD Pharmacology,
Last updated on 22 Sep 2025 | 01:43 AM (IST)

₹224 MRP ₹253.1312% off

Gurgaon

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Mesaclear-OD Tablet PR

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Same composition

Mesazed 1200mg Tablet PR

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Mesalazine (1200mg)

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General Information

Storage

Store below 30°C

The content is shown in English

Product introduction

Mesaclear-OD Tablet PR may also be used to treat another type of bowel disease known as Crohn’s ileocolitis. It should be taken with food. The dose will depend on what you are being treated for but take it exactly as your doctor prescribes. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen.

The most common side effects of this medicine include nausea, diarrhea, stomach pain, headache, itching, flatulence, and vomiting. If these symptoms bother you, do not go away, or get worse, let your doctor know. There may be ways of reducing or preventing them. Some people may get a severe allergic reaction that needs urgent medical attention. Contact your doctor immediately if you notice symptoms like swelling of the face, tongue, throat, or lips, unusual bleeding, bruising, rash, fever, sore throat, or excessive tiredness.

Before taking it, tell your doctor if you have any kidney or liver problems or a blockage in your stomach. Your age may also be a factor in deciding whether this medicine is suitable. Pregnant or breastfeeding women should also consult their doctor before taking this medicine. Let your doctor know about all other medications you are taking as some may affect, or be affected by this medicine.

Uses of Mesaclear-OD Tablet PR

Benefits of Mesaclear-OD Tablet PR

Ulcerative colitis
Ulcerative colitis is a form of inflammatory bowel disease (IBD) that causes inflammation and ulcers in the colon and rectum. Mesaclear-OD Tablet PR helps reduce the inflammation in the intestinal lining by targeting the disease locally. Reduction in inflammation promotes mucosal healing and causes symptoms like abdominal pain, diarrhea, and rectal bleeding to subside.

Crohn’s disease
Crohn’s disease is a type of inflammatory bowel disease that can affect any part of the digestive tract, causing symptoms like abdominal pain, diarrhea, and fatigue. Mesaclear-OD Tablet PR is used in mild to moderate cases to reduce inflammation and manage flare-ups. It can help prevent disease progression, reduce the need for steroids, and support intestinal health over time.

Side effects of Mesaclear-OD Tablet PR

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Mesaclear-OD

Flatulence
Headache
Vomiting
Diarrhea
Nausea
Abdominal pain
Rash
Stomach pain/epigastric pain

How to use Mesaclear-OD Tablet PR

Use it as advised by your doctor or check the label for directions before use. Mesaclear-OD Tablet PR may be taken with or without food, but it is better to take it at a fixed time.

How Mesaclear-OD Tablet PR works

Mesaclear-OD Tablet PR is an aminosalicylate. It works by suppressing the production of chemical messengers (prostaglandins) that cause inflammation (swelling) in the intestines. This reduces ulceration, bleeding and stomach pain, and prevents future flare-ups of the disease.

All substitutes for Mesaclear-OD Tablet PR

For information purposes only. Consult a doctor before taking any medicine.

Coolgut Tablet PR

by Torrent Pharmaceuticals Ltd

₹42.2/tablet pr

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Mesahenz 1200 Tablet PR

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₹21.8/tablet pr

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Mesacol OD Tablet PR

by Sun Pharmaceutical Industries Ltd

₹35.93/tablet pr

60% costlier

Vegaz OD Tablet PR

by Dr Reddy's Laboratories Ltd

₹44.33/tablet pr

98% costlier

Coloncop 1200mg Tablet PR

by Mankind Pharma Ltd

₹29.67/tablet pr

32% costlier

Quick tips

You have been prescribed Mesaclear-OD Tablet PR for treating and lowering the symptoms of mild inflammatory bowel disease such as ulcerative colitis.
Your doctor may monitor your kidney and liver functions before you start treatment with this medicine and regularly thereafter. Inform your doctor if you have severely decreased kidney or liver function.
Do not take Mesaclear-OD Tablet PR if you are allergic to aspirin or if you have blood disorders.
Do not stop taking the medication suddenly without talking to your doctor.
You have been prescribed Mesaclear-OD Tablet PR for treating and lowering the symptoms of mild inflammatory bowel disease such as ulcerative colitis.
Take it with food. Do not break, chew, or crush the tablets or granules. Swallow them whole with plenty of water.
Do not take antacids with Mesaclear-OD Tablet PR as it can make your inflammation worse.
Your doctor may monitor your kidney and liver functions before you start treatment with this medicine and regularly thereafter. Inform your doctor if you have severely decreased kidney or liver function.
Do not take Mesaclear-OD Tablet PR if you are allergic to aspirin or if you have blood disorders.

Safety advice

Alcohol

CAUTION

Caution is advised when consuming alcohol with Mesaclear-OD Tablet PR. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Mesaclear-OD Tablet PR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Mesaclear-OD Tablet PR is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
If you are taking Mesaclear-OD Tablet PR, monitor the baby for diarrhea.

Driving

SAFE

Mesaclear-OD Tablet PR does not usually affect your ability to drive.

Kidney

CAUTION

Mesaclear-OD Tablet PR should be used with caution in patients with kidney disease. Dose adjustment of Mesaclear-OD Tablet PR may be needed. Please consult your doctor.
Use of Mesaclear-OD Tablet PR is not recommended in patients with severe kidney disease.

Liver

CAUTION

Mesaclear-OD Tablet PR should be used with caution in patients with liver disease. Dose adjustment of Mesaclear-OD Tablet PR may be needed. Please consult your doctor.

Interaction with drugs

Taking Mesaclear-OD with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Moderate

Clozapine (Oral Route)

Your doctor may monitor your blood cell count and adjust the doses as per the observations.

Moderate

Azathioprine (Oral Route)

If concurrent use can not be avoided, your doctor may monitor your blood cell counts.

Moderate

Deferiprone (Oral Route)

If concurrent use can not be avoided, your doctor may monitor your blood cell counts.

Moderate

Mercaptopurine (Oral Route)

If concurrent use cannot be avoided, your doctor may monitor your blood cell counts.

Mild

Chlorpromazine (Oral Route)

Talk to your doctor if you notice any unusual symptoms.

Frequently asked questions

My symptoms have improved can I stop taking Mesaclear-OD Tablet PR?

Continue to take Mesaclear-OD Tablet PR as advised by the doctor, even if you feel better at the beginning of your treatment. Do not stop taking Mesaclear-OD Tablet PR without consulting your doctor.

Can I drink alcohol while taking Mesaclear-OD Tablet PR?

You should avoid alcohol if you have ulcerative colitis, as alcohol will irritate your stomach and intestine which will worsen your condition. Although alcohol does not interfere with the working of Mesaclear-OD Tablet PR, you should consult your doctor before taking alcohol.

Does Mesaclear-OD Tablet PR cause joint pain?

Yes, Mesaclear-OD Tablet PR may cause joint pain. If the pain continues and bothers you inform your doctor.

When is the best time to take Mesaclear-OD Tablet PR?

Take Mesaclear-OD Tablet PR exactly as directed by your doctor.

Fact Box

Chemical Class

Aminosalicylic Acids Derivative

Habit Forming

Therapeutic Class

GASTRO INTESTINAL

Action Class

5-Aminosalicylic Acid (5-ASA)

Related lab tests

Anti Neutrophilic Cytoplasmic Antibody - P

Anti Saccharomyces Cerevisiae (ASCA), IgA

Anti Saccharomyces Cerevisiae (ASCA), IgG

C- Reactive Protein Quantitative

Erythrocyte Sedimentation Rate

References

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Transcure Therapeutics Pvt Ltd
Address: 970/B/1, 1ST FLOOR, NEW VIVEK NAGAR DHOBI GHAT CHOWK LUDHIANA Ludhiana PB 141001 IN

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Mesaclear-OD Tablet PR

Save more with additional offers

General Information

Contains

Salt Synonyms

Marketer

Storage

Product introduction

Uses of Mesaclear-OD Tablet PR

Benefits of Mesaclear-OD Tablet PR

Side effects of Mesaclear-OD Tablet PR

How to use Mesaclear-OD Tablet PR

How Mesaclear-OD Tablet PR works

All substitutes for Mesaclear-OD Tablet PR

Coolgut Tablet PR

Mesahenz 1200 Tablet PR

Mesacol OD Tablet PR

Vegaz OD Tablet PR

Coloncop 1200mg Tablet PR

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Clozapine (Oral Route)

Azathioprine (Oral Route)

Deferiprone (Oral Route)

Mercaptopurine (Oral Route)

Chlorpromazine (Oral Route)

Frequently asked questions

My symptoms have improved can I stop taking Mesaclear-OD Tablet PR?

Can I drink alcohol while taking Mesaclear-OD Tablet PR?

Does Mesaclear-OD Tablet PR cause joint pain?

When is the best time to take Mesaclear-OD Tablet PR?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Anti Neutrophilic Cytoplasmic Antibody - P

Anti Saccharomyces Cerevisiae (ASCA), IgA

Anti Saccharomyces Cerevisiae (ASCA), IgG

C- Reactive Protein Quantitative

Erythrocyte Sedimentation Rate

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

Related/Popular tests