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Melcyl 10mg Tablet

Methoxsalen (10mg)

Genuine

Authenticity Assured

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required

Product Summary :

Melcyl 10mg Tablet belongs to a group of medicines called psoralens and is used with controlled UVA light (PUVA) to treat skin conditions such as psoriasis and vitiligo. It makes the skin more sensitive to UVA light, helping control excessive skin-cell growth in psoriasis and promote repigmentation in vitiligo. Take it only as prescribed and follow all eye and skin-protection instructions.

Written By Dr. Lipika Khurana, PGDHHM, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 14 Nov 2026 | 01:04 AM (IST)

MRP ₹32.16

(Inclusive of applicable taxes)

Gurgaon

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General Information

Contains

Methoxsalen (10mg)

Marketer

East West Pharma

Storage

Store below 25°C

The content is shown in English

Product introduction

Melcyl 10mg Tablet is a medicine used along with controlled ultraviolet light for effective treatment of certain skin diseases like vitiligo and psoriasis.

Melcyl 10mg Tablet is taken after meals in a dose and duration as advised by the doctor. Taking with food helps to increase the absorption of the medication as well as decrease nausea. The dose you are given will depend on your condition and how you respond to the medicine. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen. Let your doctor know about all other medications you are taking as some may affect, or be affected by this medicine.

The most common side effects of Melcyl 10mg Tablet are nausea, itching, and redness of the skin. Most of these are temporary and usually resolve with time. Contact your doctor straight away if you are at all concerned about any of these side effects. It may also cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Avoid drinking alcohol while taking this medicine as it can make dizziness worse.

Taking this medicine makes the skin more sensitive to the sun. Use sunscreen and wear protective clothing when outdoors. Try to avoid exposure of your skin and lips to sunlight for eight hours after treatment.

Uses of Melcyl Tablet

Benefits of Melcyl Tablet

Psoriasis
Psoriasis is a condition where the skin cells in the body grow too quickly and form scales and dry patches. They can grow anywhere, but most appear on the scalp, elbows, knees, and lower back. Melcyl 10mg Tablet reduces the scaly, itchy patches along with other symptoms of inflammation such as redness, swelling, or irritation which may develop on the different parts of the body. Use it for as long as it is prescribed to get the most benefit. It may take several months to become fully effective. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.

Vitiligo
Vitiligo is a condition in which the skin loses its natural color in patches. Melcyl 10mg Tablet effectively blocks that process in the skin that leads to discoloration. It also reduces any redness, rash, pain, or itchiness that may be caused by this condition. This improves your self-esteem and confidence as your appearance changes. You should always take it as prescribed to get the full benefits.

Side effects of Melcyl Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Melcyl

Nausea

How to use Melcyl Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Melcyl 10mg Tablet should be taken with or after food.

How Melcyl Tablet works

Melcyl 10mg Tablet makes the skin more sensitive to UVA light. When exposed to controlled UVA light, it interacts with the skin's DNA and slows the excessive growth of skin cells and activity of certain cells. This may help control conditions like psoriasis and vitiligo.

Dosage

Take Melcyl 10mg Tablet exactly as prescribed by your doctor and at the specified time before your scheduled UVA treatment. It is generally taken with food or milk to reduce nausea. The dose and timing may depend on the phototherapy protocol. Do not change the dose or undergo additional UVA exposure on your own.

All substitutes for Melcyl 10mg Tablet

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

Melcyl 10mg Tablet is prescribed along with UV-A rays for the treatment of vitiligo and psoriasis.
Take this treatment (methoxsalen and UVA) two or three times a week, with the treatment spaced at least forty-eight hours apart.
Always take Melcyl 10mg Tablet 2 hours before UV radiation exposure, along with food or milk.
Take a plain shower before your treatment to keep your skin clean, and pat dry.
Do not use perfumes, aftershave, deodorants, or other cosmetics or toiletries while using Melcyl 10mg Tablet, as they can make your skin even more sensitive, leading to blistering.
Use extra caution for at least 48 hours following each treatment. After each treatment, cover your skin for at least 8 hours by wearing protective clothing.
Never take Melcyl 10mg Tablet in a dose higher than the prescribed dose, as it may cause burning or blistering of your skin after exposure to UV light.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Melcyl 10mg Tablet. Please consult your doctor.

Pregnancy

UNSAFE

Melcyl 10mg Tablet is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.

Breast feeding

CONSULT YOUR DOCTOR

Information regarding the use of Melcyl 10mg Tablet during breastfeeding is not available. Please consult your doctor.

Driving

UNSAFE

Melcyl 10mg Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Melcyl 10mg Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.

Liver

CONSULT YOUR DOCTOR

There is limited data available on the use of Melcyl 10mg Tablet in patients with liver disease.

Interaction with drugs

Taking Melcyl with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Moderate

Aminophylline (Oral Route)

watch out for symptoms such as headache, nausea or tremor and consult your doctor if you experience them. They may adjust the dose of Aminophylline accordingly. Methoxsalen may raise blood levels of Aminophylline.

Moderate

Zolmitriptan (Oral Route)

If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations. Methoxsalen may raise blood levels of Zolmitriptan.

Moderate

Olanzapine (Oral Route)

If concurrent use is essential, watch out for symptoms of Olanzapine side effects such as blurred vision, sleepiness, headache, constipation, nausea, dizziness, faintness or fatigue and consult your doctor if you experience them. They may adjust the dose of Olanzapine accordingly. Methoxsalen may raise blood levels of Olanzapine.

Moderate

Olanzapine (Injection Route)

Moderate

Clozapine (Oral Route)

If concurrent use is essential, watch out for symptoms of Clozapine side effects such as blurred vision, sleepiness, headache, constipation, nausea, dizziness, faintness or fatigue and consult your doctor if you experience them. They may adjust the dose of Clozapine accordingly. Methoxsalen may raise blood levels of Clozapine.

Frequently asked questions

What is Melcyl 10mg Tablet used for?

Melcyl 10mg Tablet is used with controlled UVA light in a treatment called PUVA. It may be prescribed for skin conditions such as vitiligo and psoriasis. It should only be used under the supervision of a doctor. Taking the medicine without following the prescribed phototherapy plan may not provide the intended benefit and can increase the risk of unwanted effects.

How long does Melcyl 10mg Tablet take to show results?

The response depends on the skin condition, its severity and the individual's response to treatment. Improvement may require several sessions over weeks or longer. Continue attending scheduled sessions and follow your doctor’s advice.

Can I expose my skin to sunlight after taking Melcyl 10mg Tablet?

No. Melcyl 10mg Tablet makes your skin more sensitive to sunlight and UVA radiation. Uncontrolled exposure can cause severe redness, burns or blistering. Follow your doctor's instructions on sun avoidance, protective clothing and sunscreen.

Why do I need to wear special sunglasses after taking Melcyl 10mg Tablet?

Melcyl 10mg Tablet can make the eyes more sensitive to UVA light. Exposure during this period may damage the lens of the eye and increase the risk of cataracts. Use the prescribed UVA-blocking wrap-around sunglasses for the recommended period; ordinary sunglasses may not provide adequate protection.

Can I use sunscreen while undergoing PUVA treatment?

Your doctor may recommend sunscreen to protect skin areas that are not being treated. However, the timing of sunscreen application matters, particularly when psoriasis-affected areas are due to receive UVA treatment. Follow the phototherapy team's instructions.

Can other medicines be taken while taking Melcyl 10mg Tablet?

Yes. Some medicines, including certain antibiotics, diuretics and other photosensitising medicines, may increase sensitivity to sunlight or UVA light. Inform your doctor about all prescription medicines, over-the-counter products and supplements you use.

What should I do if my skin becomes very red or develops blisters after PUVA treatment?

Severe redness, burning or blistering may indicate an excessive reaction to UVA exposure. Avoid further sunlight or UV exposure and contact your dermatologist promptly. Do not attend another phototherapy session until you have received medical advice.

Fact Box

Chemical Class

8- methoxypsoralens

Habit Forming

Therapeutic Class

DERMA

Action Class

Psoralen & derivatives

References

Robertson DB, Maibach HI. Dermatologic Pharmacology. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 1055.
Burkhart C, Morrell D, Goldsmith L. Dermatological Pharmacology. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1813-14.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 891-92.
ScienceDirect. Methoxsalen. [Accessed 03 Apr. 2019] (online) Available from:
PubChem. Methoxsalen. [Accessed 03 Apr. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 03 Apr. 2019] (online) Available from:
Methoxsalen [patient Information]. Bengaluru, India: Strides Pharma Science Ltd.; 2019. [Accessed 25 Jul. 2024] (online) Available from:
Methoxsalen[Prescribing information]. liquid filled Strides Pharma Science Limited; 2026. [Accessed 13 Nov 2026]. Available from:

User feedback

Patients taking Melcyl 10mg Tablet

Once A Day

66%

Alternate Day

17%

Thrice A week

Twice A Week

Twice A Day

What are you using Melcyl Tablet for?

Vitiligo

75%

Psoriasis

25%

How much was the improvement?

Average

67%

Poor

33%

What were the side-effects while using Melcyl 10mg Tablet?

No Side Effect

100%

How do you take Melcyl Tablet?

With food

50%

Empty stomach

50%

Please rate Melcyl 10mg Tablet on price

Expensive

67%

Average

33%

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: East West Pharma
Address: No. 10, 2nd Cross, Maravaneri, Salem - 636007, Tamil Nadu.

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Home

Derma

Melanising Agents

Melcyl 10mg Tablet

Melcyl 10mg Tablet

Product Summary :

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Melcyl Tablet

Benefits of Melcyl Tablet

Side effects of Melcyl Tablet

How to use Melcyl Tablet

How Melcyl Tablet works

Dosage

All substitutes for Melcyl 10mg Tablet

MeLAnocyl Tablet

Kuvagold 10mg Tablet

Methnom 10mg Tablet

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Aminophylline (Oral Route)

Zolmitriptan (Oral Route)

Olanzapine (Oral Route)

Olanzapine (Injection Route)

Clozapine (Oral Route)

Frequently asked questions

What is Melcyl 10mg Tablet used for?

How long does Melcyl 10mg Tablet take to show results?

Can I expose my skin to sunlight after taking Melcyl 10mg Tablet?

Why do I need to wear special sunglasses after taking Melcyl 10mg Tablet?

Can I use sunscreen while undergoing PUVA treatment?

Can other medicines be taken while taking Melcyl 10mg Tablet?

What should I do if my skin becomes very red or develops blisters after PUVA treatment?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

References

User feedback

Patients taking Melcyl 10mg Tablet

What are you using Melcyl Tablet for?

How much was the improvement?

What were the side-effects while using Melcyl 10mg Tablet?

How do you take Melcyl Tablet?

Please rate Melcyl 10mg Tablet on price

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Disclaimer

Marketer details

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