Megmadol 650mg Tablet helps relieve pain and fever by blocking the release of certain chemical messengers responsible for fever and pain. It is used to treat headaches, migraine, toothaches, sore throats, period (menstrual) pains, arthritis, muscle aches, and the common cold.

Megmadol 650mg Tablet may be prescribed alone or in combination with another medicine. You should take it regularly as advised by your doctor. It is usually best taken with food otherwise it may upset your stomach. Do not take more or use it for longer than recommended.

Side effects are rare if this medicine is used correctly but this medicine may cause stomach pain, nausea, and vomiting in some people. Consult your doctor if any of these side effects bother you or do not go away.

This medicine is widely prescribed and considered safe but is not suitable for everybody. Before taking it, let your doctor know if you have liver or kidney problems or are using blood-thinning medicines. It may affect the dose or suitability of this medicine. Let your doctor know about all the other medicines you are taking because they may affect, or be affected by, this medicine.

Uses of Megmadol Tablet

Benefits of Megmadol Tablet

In Pain relief

Megmadol 650mg Tablet is a common painkiller for treating aches and pains. It is widely used and rarely causes any side effects if taken properly. To get the most benefits, take it as prescribed. Do not take more or for longer than needed as that can be dangerous.

In Treatment of Fever

Megmadol 650mg Tablet is also used to reduce a high temperature (fever). It works by blocking the release of certain chemical messengers that cause fever. It may be prescribed alone or in combination with other medicines. Take it as prescribed by the doctor.

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Side effects of Megmadol Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Megmadol

Stomach pain
Nausea
Vomiting

How to use Megmadol Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Megmadol 650mg Tablet is to be taken with food.

How Megmadol Tablet works

Megmadol 650mg Tablet is an analgesic (pain reliever) and anti-pyretic (fever reducer). It works by blocking the release of certain chemical messengers that cause pain and fever.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Megmadol 650mg Tablet.

Pregnancy

CONSULT YOUR DOCTOR

Megmadol 650mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

SAFE IF PRESCRIBED

Megmadol 650mg Tablet is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.

Driving

SAFE

Megmadol 650mg Tablet does not usually affect your ability to drive.

Kidney

CAUTION

Megmadol 650mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Megmadol 650mg Tablet may be needed. Please consult your doctor.
However, Megmadol 650mg Tablet contains paracetamol which is considered the safest painkiller for kidney disease patients.

Liver

CAUTION

Megmadol 650mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Megmadol 650mg Tablet may be needed. Please consult your doctor.
However, the use of Megmadol 650mg Tablet is not recommended in patients with severe liver disease and active liver disease.

What if you forget to take Megmadol Tablet?

If you miss a dose of Megmadol 650mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Megmadol 650mg Tablet

₹1.83/Tablet

Parafast 650mg Tablet

Cipla Ltd

₹1.66/tablet

9% cheaper

Parasafe 650 Tablet

Strassenburg Pharmaceuticals.Ltd

₹2.23/tablet

22% costlier

Dolo 650 Tablet

Micro Labs Ltd

₹1.96/tablet

7% costlier

Pyrigesic 650 Tablet

East India Pharmaceutical Works Ltd

₹2.06/tablet

13% costlier

P 650 Tablet

Apex Laboratories Pvt Ltd

₹2.13/tablet

16% costlier

View all substitutes

Quick tips

Megmadol 650mg Tablet should be taken with food or milk to prevent an upset stomach.
Take it as per the dose and duration prescribed by your doctor. Long-term use may lead to serious complications such as stomach bleeding and kidney problems.
Do not take indigestion remedies (antacids) within two hours of taking Megmadol 650mg Tablet.
Avoid consuming alcohol while taking this medicine as it can increase your risk of stomach problems.
Inform your doctor if you have liver disease as your dose may need to be adjusted.
The doctor may regularly monitor your kidney function, liver function, and levels of blood components if you are taking Megmadol 650mg Tablet for long-term treatment.

Fact Box

Chemical Class

P-Aminophenol Derivative

Habit Forming

Therapeutic Class

PAIN ANALGESICS

Action Class

Analgesic & Antipyretic-PCM

Interaction with drugs

Taking Megmadol with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Certoparin (Injection Route) Moderate

Concurrent use may increase the risk of liver damage. If concurrent use is essential, watch out for symptoms such as fatigue, nausea, loss of appetite, dark urine or jaundice and ... More

Cholestyramine (Oral Route) Moderate

Paracetamol may increase the effect of Cholestyramine. If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations.

Dalteparin (Injection Route) Moderate

Concurrent use may increase the risk of liver damage. If concurrent use is essential, watch out for symptoms such as fatigue, nausea, loss of appetite, dark urine or jaundice and ... More

Enoxaparin (Injection Route) Moderate

Concurrent use may increase the risk of liver damage. If concurrent use is essential, watch out for symptoms such as fatigue, nausea, loss of appetite, dark urine or jaundice and ... More

Bemiparin (Injection Route) Moderate

Concurrent use may increase the risk of liver damage. If concurrent use is essential, watch out for symptoms such as fatigue, nausea, loss of appetite, dark urine or jaundice and ... More

View all drug interactions

Patient concerns

fever and 2 months pregnant can take combiflan

Dr. Sonu Balhara Ahlawat

Obstetrics and Gynaecology

No take Crocin for pain relief

Diagnosed with viral fever along with rashes on the body. Pain in eyes since three days. Pain when open and when blinking.

Dr. Richa Jain

Ophthalmology

Orbital pain is common with viral fever. Go to physician for fever. It will be relieved with relief in fever

FAQs

What if I vomit after taking Megmadol 650mg Tablet?

If you vomit in less than 30 minutes after having a dose of Megmadol 650mg Tablet tablets or syrup, retake the same dose again. If you vomit after 30 minutes of a dose, you do not need to take another one until the next standard dose.

When will I feel better after taking the Megmadol 650mg Tablet?

Usually, you will start feeling better after about half an hour of taking a Megmadol 650mg Tablet.

How often can I take the Megmadol 650mg Tablet?

You should only take four doses of Megmadol 650mg Tablet in 24 hours. There should be a gap of at least 4 hours between two doses. Do not take Megmadol 650mg Tablet for more than 3 days without consulting a doctor first.

Is Megmadol 650mg Tablet an antibiotic?

No, Megmadol 650mg Tablet is not an antibiotic. It works as a painkiller and fever-reducing medicine.

Can I take Megmadol 650mg Tablet and ibuprofen together?

Ibuprofen and Megmadol 650mg Tablet are safe medicines, but both should not be used together. Consult your doctor if you are not sure.

How long does a Megmadol 650mg Tablet take to work?

Megmadol 650mg Tablet takes around 30-45 min to start working and show its effects. It is advised to take this medicine for the duration suggested by the doctor. Consult your doctor if you experience any bothersome side effects.

What are the serious side effects of taking an excess of the Megmadol 650mg Tablet?

Overdose of Megmadol 650mg Tablete may cause severe life-threatening liver injury. Taking more than the prescribed dose may also cause kidney injury, decreased platelet count, and even coma. Early symptoms of an overdose include nausea, vomiting, and general tiredness. Immediately consult a doctor or reach an emergency in case of a suspected overdose.

Can Megmadol 650mg Tablet cause nausea and vomiting?

Yes, Megmadol 650mg Tablet may cause nausea and vomiting. Taking it with milk, food or antacids can prevent nausea. Avoid taking fatty or fried foods along with this medication. In case of vomiting, drink plenty of water or other fluids by taking small frequent sips. Talk to your doctor if vomiting persists and you notice signs of dehydration, like dark colored and strong-smelling urine or a low frequency of urination. Do not take any other medicines without speaking to your doctor.<br>

Is Megmadol 650mg Tablet helpful in relieving stomach pain due to indigestion?

No, Megmadol 650mg Tablet should not be taken for stomach pain without consulting a doctor. This drug can increase stomach acid secretion which may aggravate an unknown underlying condition.

Can I take Megmadol 650mg Tablet with an antibiotic?

Yes, taking Megmadol 650mg Tablet and antibiotics at the same time should not cause any problems. Antibiotics are used to help clear infections but often don't do anything to relieve pain. Therefore you can generally take Megmadol 650mg Tablet alongside your antibiotics. However, always consult your doctor before taking any medications.

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Related lab tests

Complete Blood Count

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Furst DE, Ulrich RW, Varkey-Altamirano C. Nonsteroidal Anti-Inflammatory Drugs, Disease Modifying Antirheumatic Drugs, Nonopioids Analgesics, & Drugs Used in Gout. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 635-36.
Grosser T, Smyth E, FitzGerald GA. Anti-Inflammatory, Antipyretic, and Analgesic Agents; Pharmacotherapy of Gout. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 982-84.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 8-12.
Paracetamol. County Tipperary, Ireland: Pinewood Healthcare; 2015. [Accessed 17 Jun. 2019] (online) Available from:
Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 02 Apr. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 02 Apr. 2019] (online) Available from:

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