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Manohexy Injection

Trihexyphenidyl (2mg)
Genuine
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required
Manohexy Injection is used with other medicines to treat Parkinson’s disease. It is also used to treat severe movement side effects caused by certain drugs (drug-induced movemnet disorder).

Written By Dr. Syeda Aafia, MBA, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 23 Sep 2025 | 06:40 PM (IST)
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1 ml Injection
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Manohexy Injection image
Manohexy Injection image

Product introduction

Manohexy Injection is given under the supervision of a healthcare professional. Do not skip any doses and finish the full course of treatment even if you feel better. It is important that this medication is not stopped suddenly without talking to doctor as it may result in a worsening of symptoms.

Some common side effects of this medicine include nausea, vomiting, constipation, and blurred vision. It even causes dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Dry mouth may occur commonly while using this medicine so, try to do frequent mouth rinses, maintain good oral hygiene, and increase water intake. Avoid wearing contact lenses as it may cause dry eyes as well. It is important to inform your doctor if you suffer from glaucoma or have trouble in passing urine.

Before using Manohexy Injection, you should tell your doctor if you've ever had heart problems, problems with passing urine, liver or kidney disease. It may also affect, or be affected by, some other drugs you are using so let your doctor know what these are to be safe. Pregnant or breastfeeding mothers should consult their doctor before starting treatment with this medicine.

Benefits of Manohexy Injection

Treatment of Parkinson's disease
Parkinson’s disease (PD) is a disorder of the central nervous system. It makes the muscles stiff which causes difficulties in standing and walking. PD also causes tremors and loss of balance. Manohexy Injection helps to treat the symptoms of Parkinson's Disease. It relaxes the stiff muscles and helps in easy movement without losing balance. Manohexy Injection is also used to treat side effects like abnormal movements caused by antipsychotic drugs.

It is advisable not to stop this medicine without consulting your doctor. This is because a sudden stoppage can cause symptoms of Parkinson's disease to return. You can see that the drug is working if you are able to do your daily activities more easily and have a more active and better quality of life.
Treatment of Drug induced abnormal movements
Manohexy Injection is also used to treat side effects like abnormal movements caused by antipsychotic drugs. It helps restore normal body posture as well as control over muscle movements in the body. This will enable you to lead a normal life and improve your ability to carry out daily activities.

How to use Manohexy Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Manohexy Injection works

Manohexy Injection is an anticholinergic medication. It works by decreasing the activity of a chemical messenger (acetylcholine) in the brain. This improves muscle control and reduces stiffness in Parkinson's disease. It also improves movement disorder (restlessness, involuntary movements or muscle spasm) caused by certain other medicines.

Quick tips

  • Dry mouth may occur as a side effect. Frequent mouth rinses, good oral hygiene, increased water intake and sugarless candy may help.
  • It may cause dry eyes. Avoid wearing contact lenses and inform your doctor if it bothers you.
  • It may cause dizziness and sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.
  • Inform your doctor if you suffer from  glaucoma or if you have trouble passing urine.
  • Monitoring of intraocular pressure is required while taking this medicine, as an increase in eye pressure may cause blurry vision.
  • Dry mouth may occur as a side effect. Frequent mouth rinses, good oral hygiene, increased water intake and sugarless candy may help.
  • It may cause dry eyes. Avoid wearing contact lenses and inform your doctor if it bothers you.
  • It may cause dizziness and sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.
  • Monitoring of intraocular pressure is required while taking this medicine, as an increase in eye pressure may cause blurry vision.
  • Inform your doctor if you suffer from  glaucoma or if you have trouble passing urine.

Safety advice

Alcohol

Alcohol

UNSAFE
Manohexy Injection may cause excessive drowsiness with alcohol.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Manohexy Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding

Breast feeding

SAFE IF PRESCRIBED
Manohexy Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving

Driving

UNSAFE
Manohexy Injection may cause side effects which could affect your ability to drive.
Manohexy Injection can cause blurring of vision, dizziness, mild nausea, and mental confusion in some cases. This may affect your ability to drive.
Kidney

Kidney

CONSULT YOUR DOCTOR
There is limited information available on the use of Manohexy Injection in patients with kidney disease. Please consult your doctor.
Patients with kidney disease should be closely monitored by a doctor while taking this medicine.
Liver

Liver

CONSULT YOUR DOCTOR
There is limited information available on the use of Manohexy Injection in patients with liver disease. Please consult your doctor.

Interaction with drugs

Taking Manohexy with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Moderate

Thioridazine (Oral Route)

Talk to your doctor if you notice any unusual symptoms.
Moderate

Amitriptyline (Oral Route)

Talk to your doctor if you notice any unusual symptoms.
Moderate

Amoxapine (Oral Route)

Talk to your doctor if you notice any unusual symptoms.
Moderate

Atropine (Injection Route)

Talk to your doctor if you notice any unusual symptoms.
Moderate

Baclofen (Injection Route)

Talk to your doctor if you notice any unusual symptoms.

Frequently asked questions

No, Manohexy Injection is not a narcotic. However, its hallucinogenic and euphoriant properties may make the people abuse its use.
Yes, Manohexy Injection may cause drowsiness in some cases. Some people may even experience difficulty in falling asleep. Do not drive or operate heavy machinery when you experience drowsiness or if it causes blurring of vision, dizziness, mild nausea and mental confusion.
Yes, Manohexy Injection may cause weight gain. If you are concerned about your weight gain, consult a dietician for diet plan, exercise regularly, and eat a healthy and nutritious diet.
No, Manohexy Injection is not a narcotic. However, its hallucinogenic and euphoriant properties may make the people abuse its use.
Yes, Manohexy Injection may cause drowsiness in some cases. Some people may even experience difficulty in falling asleep. Do not drive or operate heavy machinery when you experience drowsiness or if it causes blurring of vision, dizziness, mild nausea and mental confusion.
Yes, Manohexy Injection may cause weight gain. If you are concerned about your weight gain, consult a dietician for diet plan, exercise regularly, and eat a healthy and nutritious diet.
No, Manohexy Injection should not be crushed. It should be swallowed as a whole with a glass of water. Consult your doctor if you are not sure about how to take this medicine.
Manohexy Injection may be taken before or after meals according to the effects experienced by the patient. If Manohexy Injection tends to dry the mouth excessively, it may be better to take it before meals, unless it causes nausea. If taken after meals, it may cause induced thirst which can be reduced by peppermint, chewing gum, or water.
You should continue taking Manohexy Injection as long as your doctor advises you. In some cases, the use of Manohexy Injection may continue indefinitely. Such patients are often kept under careful observation for a longer period of time.
You should not stop taking Manohexy Injection without consulting your doctor as your symptoms may get worse. If you feel your dose needs to be lowered, then consult your doctor who will reduce your dose gradually.
No, Manohexy Injection is not a narcotic. However, its hallucinogenic and euphoriant properties may make the people abuse its use.
Yes, Manohexy Injection may cause drowsiness in some cases. Some people may even experience difficulty in falling asleep. Do not drive or operate heavy machinery when you experience drowsiness or if it causes blurring of vision, dizziness, mild nausea and mental confusion.
Yes, Manohexy Injection may cause weight gain. If you are concerned about your weight gain, consult a dietician for diet plan, exercise regularly, and eat a healthy and nutritious diet.
No, Manohexy Injection should not be crushed. It should be swallowed as a whole with a glass of water. Consult your doctor if you are not sure about how to take this medicine.
Manohexy Injection may be taken before or after meals according to the effects experienced by the patient. If Manohexy Injection tends to dry the mouth excessively, it may be better to take it before meals, unless it causes nausea. If taken after meals, it may cause induced thirst which can be reduced by peppermint, chewing gum, or water.
You should continue taking Manohexy Injection as long as your doctor advises you. In some cases, the use of Manohexy Injection may continue indefinitely. Such patients are often kept under careful observation for a longer period of time.
You should not stop taking Manohexy Injection without consulting your doctor as your symptoms may get worse. If you feel your dose needs to be lowered, then consult your doctor who will reduce your dose gradually.

Fact Box

Chemical Class

Aralkylamines Derivative

Habit Forming

No

Therapeutic Class

NEURO CNS

Action Class

Anticholinergic- centrally acting

References

  1. Stahl SM, editor. Trihexyphenidyl. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 697-99.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 1405.
  3. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Trihexyphenidyl. [Updated 2018 Dec 3]. [Accessed 20 Feb. 2020] (online) Available from:
  4. Trihexyphenidyl [Product Label]. Pearl River, NY: Lederle Pharmaceutical Division; 2003. [Accessed 20 Feb. 2024] (online) Available from:
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Orchid Chemicals & Pharmaceuticals Ltd
Address: Orchid Towers', #313, Valluvar Kottam High Road, Nungambakkam, Chennai - 600 034, Tamil Nadu, India

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Manohexy Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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