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    Information about Trihexyphenidyl

    Trihexyphenidyl uses

    Trihexyphenidyl is used in Parkinson's disease and drug induced abnormal movements.

    How trihexyphenidyl works

    Trihexyphenidyl is a muscle relaxing medication. It works by decreasing the activity of excess acetylcholine in the brain. This improves muscle control and reduces stiffness. It helps patients with Parkinson's disease by improving muscle control and reducing stiffness so that they can move more naturally. It is also used to treat movement disorder (restlessness, involuntary movements or muscle spasm ) which can be caused by certain drugs.

    Common side effects of trihexyphenidyl

    Dryness in mouth, Nausea, Vomiting, Constipation, Blurred vision

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    Expert advice for Trihexyphenidyl

    • It may be taken before or after meals.
    • If Trihexyphenidyl causes your mouth to dry excessively, it may be better to take it before meals, unless it causes nausea. If taken after meals, thirst can be improved by sucking hard sugarless candy, chewing gum, or drinking water.
    • Inform your doctor if you are taking any medicines to treat glaucoma.
    • Trihexyphenidyl can cause blurred vision or dizziness. Do not drive and or operate machinery if you get blurred vision or dizziness.
    • Inform your doctor if you have trouble in passing urine.
    • Inform your doctor if you have ever been diagnosed with kidney or liver problems.

    Frequently asked questions for Trihexyphenidyl


    Q. What is Trihexyphenidyl used for?

    Trihexyphenidyl is used in the management of Parkinson's disease as an add-on medicine along with other medicines. It helps by improving muscle control and reducing the stiffness of the muscle so that they can move naturally. Trihexyphenidyl can also be used to treat movement disorders (extreme restlessness, involuntary movements or muscle spasms) which can be caused by certain drugs.

    Q. How does Trihexyphenidyl work?

    Trihexyphenidyl works by blocking the action of a chemical messenger known as acetylcholine on the nerves of the smooth muscles; thereby, reducing the muscle spasm (involuntary contraction of a muscle or group of muscles), tremor (uncontrolled shaking) and excessive salivation associated with Parkinson's disease.

    Q. Is Trihexyphenidyl a narcotic substance?

    No, Trihexyphenidyl is not a narcotic substance. Trihexyphenidyl is an antispasmodic(muscle relaxing) medicine and belongs to a group of medicines known as anticholinergics.

    Q. Is Trihexyphenidyl safe?

    Trihexyphenidyl is a safe medicine if used at prescribed doses for the prescribed duration as advised by the doctor.

    Q. What is Trihexyphenidyl?

    Trihexyphenidyl is an antispasmodic (muscle relaxing) drug and belongs to a group of drugs known as 'anticholinergics'.

    Q. Does Trihexyphenidyl get you high?

    Trihexyphenidyl has been reported to get you a high. Please use this drug only for prescribed duration in doses as recommended by your doctor.

    Q. Does Trihexyphenidyl cause weight gain?

    Trihexyphenidyl has not been seen to cause weight gain. However, weight loss has been reported with Trihexyphenidyl in children. Please consult your doctor in case you experience an unexpected change in your weight while you are taking Trihexyphenidyl.

    Content on this page was last updated on 12 March, 2018, by Dr. Varun Gupta (MD Pharmacology)