Information about Amoxapine

Amoxapine Uses

Amoxapine is used in the treatment of depression. It is used in patients intolerant of or unresponsive to alternative treatment options for depression.

How Amoxapine works

Amoxapine is a tricyclic antidepressant. It increases the levels of chemical messengers in the brain that help in regulating the mood and treat depression.

Common side effects of Amoxapine

Weight gain, Dryness in mouth, Abnormality of voluntary movements, Difficulty in urination, Increased heart rate, Orthostatic hypotension (sudden lowering of blood pressure on standing), Constipation, Parkinsonism, Akathisia (inability to stay still), Dystonia (involuntary muscle contractions), Insomnia (difficulty in sleeping), Drowsiness
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Reviewed By
MD Pharmacology, MBBS
Last updated
13 Jun 2023 | 11:26 AM (UTC)

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Available Medicine for Amoxapine

AmolifeLa Pharmaceuticals
94 to ₹1072 variant(s)
OxcapSunrise Remedies Pvt Ltd
45 to ₹802 variant(s)
DemoloxPfizer Ltd
43 to ₹812 variant(s)
77 to ₹842 variant(s)
AxaBiologic Psychotropics India Pvt Ltd
1601 variant(s)
A PinePsycogen Captab
49 to ₹992 variant(s)
DepsacTheo Pharma Pvt Ltd
1361 variant(s)
KamipoxKC Laboratories
38 to ₹722 variant(s)
AuxadepJagsam Pharma
1901 variant(s)

Expert advice for Amoxapine

  • You have been prescribed Amoxapine for the treatment of depression.
  • Drink plenty of fluids as it may cause dehydration and constipation.
  • Monitor your weight during the treatment as Amoxapine can cause weight gain and increased appetite.
  • It may cause sleepiness. Don't drive or do anything requiring concentration until you know how Amoxapine affects you.
  • Talk to your doctor if you notice sudden mood changes, unusual movements or develop suicidal thoughts.

Frequently asked questions for Amoxapine


Q. What is Amoxapine used for?

Amoxapine is a medicine used to treat depression. It restores the balance of certain chemicals (neurotransmitters) in the brain that are responsible for depression along with anxiety or agitation. This helps to elevate the mood and enhances the behavior by creating a feeling of well being.

Q. What are the side effects of Amoxapine?

The common side effects of Amoxapine are an increased heart rate, orthostatic hypotension (sudden decrease in blood pressure on standing), dryness in mouth, abnormality of voluntary movements, weight gain, difficulty in urination and constipation. Please consult your doctor if any of these side effects worry you. The doctor will suggest ways to manage or prevent them.

Q. I feel better now, can I stop taking Amoxapine?

No, you should not stop taking Amoxapine without discussing it with your doctor even if you feel better. This is because if you stop taking it suddenly, your depression may come back and your symptoms may worsen. Your doctor will decide for how long you need to continue this medicine. Consult your doctor if any of the side effects bother you. If you have completed your course of treatment, your doctor may decrease your dose gradually before taking you off this medicine.

Q. Is there anything I need to be careful about while on therapy with Amoxapine?

Amoxapine may cause drowsiness and dizziness, especially in the beginning of the treatment. Do not drive or work with tools or machinery if your alertness is affected. It is not advisable to drink alcohol during treatment with this medicine as it might worsen the drowsiness. Let your doctor know if you have any problems with your liver or kidneys and if you are on any medicines or supplements. This is because medicines may have interactions with each other and cause allergic reactions that can sometimes be serious. Inform your doctor if you are pregnant, planning to conceive or breastfeeding to prevent any harmful effects on the baby.

Q. Does Amoxapine cause any effect on pregnancy or the newborn?

Do not take Amoxapine during pregnancy unless prescribed by the doctor. If you take this medicine during the last trimester of the pregnancy, the newborn may develop symptoms such as irritability or loud crying, rigidity (stiffness of limbs), irregular body movements, irregular breathing, poor feeding, difficulty in urinating or passing stools.


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