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Macromycin Tablet

Spiramycin (3Million IU)

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Macromycin Tablet is an antibiotic used to treat a parasitic infection known as Toxoplasmosis in pregnant women. It helps to lower the risk of transmission of toxoplasma infection from the mother to the unborn child. Rarely, it may also be used to treat some other infections.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 22 May 2026 | 06:22 PM (IST)

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General Information

Contains

Spiramycin (3Million IU)

Marketer

Macleods Pharmaceuticals Pvt Ltd

Storage

Store below 25°C

The content is shown in English

Product introduction

Macromycin Tablet should be taken orally on an empty stomach. Do not skip any doses and finish the full course of treatment even if you feel better. Stopping the medicine too early may lead to the infection returning or worsening.

Commonly seen side effects seen with this medicine include nausea, vomiting, stomach pain, and diarrhea. These are usually temporary and subside with the completion of treatment. Consult your doctor if these side effects do not resolve or persist for a longer duration.

Regular monitoring of liver function tests (LFT’s) may be required while using this medicine. This medicine is safe to use during pregnancy. However, it will not affect the severity of the disease if the unborn child has already been infected. Inform your doctor if you have any previous history of allergy before taking this medicine.

Uses of Macromycin Tablet

Toxoplasmosis during pregnancy

Benefits of Macromycin Tablet

Toxoplasmosis during pregnancy
Toxoplasmosis or Toxoplasma infection is an infection that can cause complications such as miscarriage, stillbriths and damage to baby’s brain and other organs articularly the eyes, at birth or early childhood or even as adults. Macromycin Tablet helps in preventing this infection in the unborn baby from their mother, and also decreases the progression as well as worsening of the symptoms, such as eye disorders, in already infected babies. Earlier diagnosis of the infection can help in preventing it efficiently during pregnancy. Take it as prescribed to get the most benefit.

Side effects of Macromycin Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Macromycin

Nausea
Vomiting
Abdominal pain
Diarrhea

How to use Macromycin Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Macromycin Tablet is to be taken on an empty stomach.

How Macromycin Tablet works

Macromycin Tablet is an antibiotic. It works by preventing synthesis of essential proteins required by bacteria to carry out vital functions. Thus, it stops the bacteria from growing, and prevents the infection from spreading.

All substitutes for Macromycin Tablet

For information purposes only. Consult a doctor before taking any medicine.

Rovamycin Forte Tablet

by Abbott

₹89.8/tablet

60% costlier

Quick tips

Your doctor has prescribed Macromycin Tablet to lower the risk of transmission of toxoplasma infection to your unborn child.
Do not skip any doses and finish the full course of treatment even if you feel better.
It is safe to use in the first trimester of pregnancy.
Take it with food to avoid an upset stomach.
Diarrhea may occur as a side effect but should stop when your course is complete. Inform your doctor if it doesn't stop or if you find blood in your stools.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Macromycin Tablet. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

The safety of Macromycin Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding

CAUTION

Macromycin Tablet should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from the body.

Driving

CONSULT YOUR DOCTOR

It is not known whether Macromycin Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.

Kidney

CONSULT YOUR DOCTOR

There is limited data available on the use of Macromycin Tablet in patients with kidney disease. Please consult your doctor.

Liver

CONSULT YOUR DOCTOR

There is limited data available on the use of Macromycin Tablet in patients with liver disease.

Interaction with drugs

Taking Macromycin with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Life-threatening

Domperidone (Oral Route)

Do not consume Domperidone with Spiramycin.

Life-threatening

Disopyramide (Oral Route)

Do not consume Disopyramide with Spiramycin. If concurrent use is essential, please consult your doctor. Factors such as old age, chronic heart issues, or low potassium levels may more frequently cause disturbance in heart rhythm, and your doctor may consider ECG monitoring in their presence.

Severe

Amiodarone (Oral Route)

Factors such as old age, chronic heart issues, or low potassium levels may more frequently cause disturbance in heart rhythm, and your doctor may consider ECG monitoring in their presence.

Severe

Pimozide (Oral Route)

Factors such as old age, chronic heart issues, or low potassium levels may more frequently cause disturbance in heart rhythm, and your doctor may consider ECG monitoring in their presence.

Severe

Haloperidol (Oral Route)

Factors such as old age, chronic heart issues, or low potassium levels may more frequently cause disturbance in heart rhythm, and your doctor may consider ECG monitoring in their presence.

Frequently asked questions

Can the use of Macromycin Tablet cause diarrhea?

Yes, the use of Macromycin Tablet can cause diarrhea. It is an antibiotic which kills the harmful bacteria. However, it also affects the helpful bacteria in your stomach or intestine and causes diarrhea. If you are experiencing severe diarrhea, talk to your doctor about it.

How long does Macromycin Tablet takes to work?

Usually, Macromycin Tablet starts working soon after taking it. However, it may take some days to kill all the harmful bacteria and make you feel better.

What if I don't get better after using Macromycin Tablet?

Inform your doctor if you don't feel better after finishing the full course of treatment. Also, inform him if your symptoms are getting worse while using this medicine.

Can I stop taking Macromycin Tablet when my symptoms are relieved?

No, do not stop taking Macromycin Tablet and complete the full course of treatment even if you feel better. Your symptoms may improve before the infection is completely cured.

Can the use of Macromycin Tablet cause infertility?

There is no firm evidence to suggest that the use of Macromycin Tablet will cause infertility in males or females.

Fact Box

Chemical Class

Macrolide antibiotics

Habit Forming

Therapeutic Class

ANTI INFECTIVES

Action Class

Macrolides

Related lab tests

TORCH Profile IgG & IgM 10 Parameters

Toxoplasma DNA PCR - Qualitative

Toxoplasma gondii - IgG

Toxoplasma gondii - IgM

References

Phillips MA, Stanley SL Jr. Chemotherapy of Protozoal Infections: Amebiasis, Giardiasis, Trichomoniasis, Trypanosomiasis, Leishmaniasis, and Other Protozoal Infections. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1421.
ScienceDirect. Spiramycin. [Accessed 31 Mar. 2019] (online) Available from:
Azithromycin. New York, New York: Pfizer Inc.; 2013. [Accessed 08 Apr. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 31 Mar. 2019] (online) Available from:
Spiramycin [Product Monograph]. Montreal, Canada: Odan Laboratories Ltd.; 2018. [Accessed 25 Jul. 2024] (online) Available from:

User feedback

Patients taking Macromycin Tablet

Once A Day

49%

Twice A Day

44%

Thrice A Day

Once A Month

What are you using Macromycin Tablet for?

Toxoplasmosis during pregnancy

60%

Others

20%

Bacterial infections

20%

How much was the improvement?

Poor

83%

Average

17%

What were the side-effects while using Macromycin Tablet?

No Side Effect

100%

How do you take Macromycin Tablet?

With food

100%

Please rate Macromycin Tablet on price

Not Expensive

100%

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Macleods Pharmaceuticals Pvt Ltd
Address: Atlanta Arcade, Marol Church Road, Andheri (East), Mumbai - 400059, INDIA.

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Macromycin Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

Lab tests offered by us

Why we need a prescription?

Home

Anti Infectives

Macrolides And Similar Types

Macromycin Tablet

Macromycin Tablet

Cash on delivery

Free Return

Expiry after

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Macromycin Tablet

Benefits of Macromycin Tablet

Side effects of Macromycin Tablet

How to use Macromycin Tablet

How Macromycin Tablet works

All substitutes for Macromycin Tablet

Rovamycin Forte Tablet

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Domperidone (Oral Route)

Disopyramide (Oral Route)

Amiodarone (Oral Route)

Pimozide (Oral Route)

Haloperidol (Oral Route)

Frequently asked questions

Can the use of Macromycin Tablet cause diarrhea?

How long does Macromycin Tablet takes to work?

What if I don't get better after using Macromycin Tablet?

Can I stop taking Macromycin Tablet when my symptoms are relieved?

Can the use of Macromycin Tablet cause infertility?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

TORCH Profile IgG & IgM 10 Parameters

Toxoplasma DNA PCR - Qualitative

Toxoplasma gondii - IgG

Toxoplasma gondii - IgM

References

User feedback

Patients taking Macromycin Tablet

What are you using Macromycin Tablet for?

How much was the improvement?

What were the side-effects while using Macromycin Tablet?

How do you take Macromycin Tablet?

Please rate Macromycin Tablet on price

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

In case of any issues, contact us

Lab tests offered by us

Related/Popular tests