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MMST, MBBS
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MD (Pharmacology), MBBS
Last updated:
21 Feb 2020 | 12:19 PM (IST)
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Mabtas N 100mg Injection

Prescription Required
SALT COMPOSITION
Storage
Store in a refrigerator (2 - 8°C). Do not freeze.

Introduction

Mabtas N 100mg Injection is used in the treatment of non-Hodgkin lymphoma (NHL), rheumatoid arthritis, blood cancer (chronic lymphocytic leukemia), granulomatosis with polyangiitis and microscopic polyangiitis.

Mabtas N 100mg Injection is given as an injection under the supervision of doctor. You must take it in a dose as advised by the doctor. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

The most common side effects of this medicine include headache, weakness, edema, infection, and hair loss. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with hepatitis B.

Before taking it, tell your doctor if you have heart disease, liver, or planning surgery or vaccination or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

Uses of Mabtas N Injection

Side effects of Mabtas N Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Mabtas N

  • Headache
  • Weakness
  • Edema (swelling)
  • Infection
  • Hair loss
  • Itching
  • Chills
  • Febrile neutropenia
  • Decreased white blood cell count (neutrophils)
  • Infusion reaction
  • Increased risk of infection
  • Decreased blood cells (red cells, white cells, and platelets)

How to use Mabtas N Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Mabtas N Injection works

Mabtas N 100mg Injection is a monoclonal antibody. It works by targeting the unwanted activity of immune cells (B cells) in rheumatoid arthritis and certain types of cancers.

Safety Advice

Alcohol
CAUTION
Caution is advised when consuming alcohol with Mabtas N 100mg Injection. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Mabtas N 100mg Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breastfeeding
SAFE IF PRESCRIBED
Mabtas N 100mg Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving
CONSULT YOUR DOCTOR
It is not known whether Mabtas N 100mg Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney
SAFE IF PRESCRIBED
Mabtas N 100mg Injection is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Mabtas N 100mg Injection may not be needed in these patients. Please consult your doctor.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Mabtas N 100mg Injection in patients with liver disease. Please consult your doctor.
Use of Mabtas N 100mg Injection is not recommended in patients with the active liver disease or those who had viral hepatitis as it can reactivate the infection.

What if you forget to take Mabtas N Injection?

If you miss a dose of Mabtas N 100mg Injection, please consult your doctor.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Mabtas N 100mg Injection
₹738.94/ml of Injection
Maball 100mg Injection
Hetero Drugs Ltd
₹610.81/ml of Injection
save 17%
Mabtas T 100mg Injection
Intas Pharmaceuticals Ltd
₹750/ml of Injection
2% costlier
Reditux 100 Injection
Dr Reddy's Laboratories Ltd
₹770.83/ml of Injection
4% costlier
Rituxirel 100mg Injection
Reliance Life Sciences
₹770.83/ml of Injection
4% costlier
Ristova 100mg Injection
Roche Products India Pvt Ltd
₹7707/Injection
943% costlier

Quick Tips

  • It is given as a drip (intravenous infusion) by your doctor or nurse.
  • You may be given some painkillers, antihistamine and possibly steroids before the drip to help prevent infusion reaction.
  • Your doctor may get blood tests done to check for hepatitis B before treatment and to monitor your blood cells during treatment with this medicine.
  • Inform your doctor immediately if you notice any signs of infection such as fever, sore throat or rash.
  • Inform your doctor if you are pregnant, planning to conceive or breastfeeding.
  • Inform your doctor  if you have any heart rhythm problems, if you are having surgery or if you plan to get any vaccinations.

Fact Box

Chemical Class
Monoclonal antibody (mAb)
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS

Patient Concerns

arrow
Non Hodgkin lymphoma of defuss large b cells
Dr. Vijay Sharnangat
Medical Oncology and Hematology
I am very much experienced in treating DLBCL
Suffering from rheumatoid arthritis Now she is medicating with lefno 20 mg n folitrax 20 mg
Dr. Akshat Goel
Orthopaedics
Refer to a Rheumatologist
arrow
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Disclaimer:

1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Chabner BA, Barnes J, Neal J, et al. Targeted Therapies: Tyrosine Kinase Inhibitors, Monoclonal Antibodies, and Cytokines. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1745-48.
  2. Lake DF, Briggs AD, Akporiaye ET. Immunopharmacology. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 978.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1225-27.
  4. Rituximab. Garden City, Hertfordshire: Roche Products Limited; 1998 [revised 18 Dec. 2018]. [Accessed 25 Jan. 2019] (online) Available from:External Link
  5. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Rituximab. [Updated 2020 Jan 20]. [Accessed 18 Feb. 2020] (online) Available from:External Link

Manufacturer/Marketer Address

Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Best Price
₹6280.97
MRP7389.38  Get 15% OFF
10 ml in 1 vial
SOLD OUT

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