


Loxipe 25mg Capsule
Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 25 Nov 2025 | 03:05 PM (IST)

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General Information



Product introduction
Loxipe 25mg Capsule should be taken with food, preferably at the same time each day. Take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration as advised by your doctor and if you have missed a dose, take it as soon as you remember it. Do not skip any doses and finish the full course of treatment even if you feel better. This medication mustn't be stopped suddenly without talking to your doctor as it may worsen your symptoms.
Some common side effects of this medicine include dry mouth, abnormality of voluntary movements, urinary retention, constipation, and muscle rigidity. Initially, this medicine may cause a sudden drop in blood pressure when you change positions, rise slowly if you have been sitting or lying down. It may also cause dizziness and sleepiness, do not drive or do anything that requires mental focus until you know how this medicine affects you.
Before taking it, inform your doctor if you are suffering from thyroid or kidney problems, epilepsy, Parkinson’s disease, glaucoma, or any heart problems. You should not take this medicine if you are under the influence of alcohol or any sleep-inducing, cough, and/ or allergy medication. This medicine can also lead to weight gain, eat a healthy balanced diet, avoid snacking with high-calorie food, and exercise regularly.
Uses of Loxipe Capsule
Benefits of Loxipe Capsule
Loxipe 25mg Capsule helps in maintaining the balance of certain chemicals in the brain that affect mood and behavior. This improves your mood, relieves anxiety, tension, helps you sleep better, and increases your energy levels. Loxipe 25mg Capsule prevents extreme changes in mood and helps you feel less agitated. You may experience fewer episodes of depression and low mood.
Schizophrenia is a mental disorder in which a person’s thinking ability, feelings, and behavior become abnormal. Loxipe 25mg Capsule helps restore the chemical imbalances in the brain that are responsible for such changes. It improves thoughts, behavior and enhances the quality of life.
Loxipe 25mg Capsule works to restore the normal balance of nerve activity in your brain. It can help prevent extreme changes in mood and help you feel less agitated. You may experience fewer episodes of low mood. It can take several weeks for this medicine to work and you may still feel low during this time. It is likely that you will take this medicine for at least six months but possibly much longer. It needs to be taken regularly to work effectively. Do not stop taking it unless your doctor advises you to. You should continue to eat well and keep fit to reduce symptoms of bipolar disorder.
Side effects of Loxipe Capsule
- Sleepiness
- Orthostatic hypotension (sudden lowering of blood pressure on standing)
- Dryness in mouth
- Abnormality of voluntary movements
- Weight gain
- Increased prolactin level in blood
- Urinary retention
- Constipation
- Muscle stiffness
- Tremors
How to use Loxipe Capsule
How Loxipe Capsule works
All substitutes for Loxipe 25mg Capsule
Quick tips
- Loxipe 25mg Capsule should be taken with food, preferably at the same time every day.
- Use caution while driving or doing anything that requires concentration as Loxipe 25mg Capsule can cause dizziness and sleepiness.
- Immediately inform the doctor if the person taking Loxipe 25mg Capsule starts to have breathing problems.
- Older people who have memory loss and psychosis have a higher risk of death if they take Loxipe 25mg Capsule.Â
- Do not stop taking the medicine without talking to your doctor as it can worsen the condition.Â
Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver
Interaction with drugs
Memantine (Oral Route)
Clozapine (Oral Route)
Frequently asked questions
Fact Box
Chemical Class
Habit Forming
Therapeutic Class
Action Class
References
- Stahl SM, editor. Loxapine. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 377-82.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 825-26.
- Loxapine [FDA Label]. Mountain View, CA: Alexza Pharmaceuticals, Inc.; 1975. [Accessed 02 Mar. 2020] (online) Available from:
- Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Loxapine. [Updated 2018 Oct 31]. [Accessed 20 Feb. 2020] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 25 Mar. 2019] (online) Available from:




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