Medicine Overview of Loxetine Tablet
Side Effects of Loxetine are Nausea, Headache, Dryness in mouth, Sleepiness, Dizziness.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Loxetine 30 mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
Loxetine 30 mg Tablet works by increasing the levels of chemical messengers (serotonin and noradrenaline), natural substances in the brain that help maintain mental balance and stop the movement of pain signals in the brain.
In Depth Information on Loxetine Tablet
You may have to wait for 2 to 4 weeks to get the full effect.
- If your doctor asks you to stop Loxetine 30 mg Tablet, you should not discontinue it abruptly. Many patients tolerate decreasing 50% dose every 3 days however if the withdrawal symptoms emerge during tapering it would require more gradual tapering over few weeks.
- Inform your doctor if you have ever been diagnosed with any heart problems (heart attack, heart failure, slow or irregular heart rate).
- Inform your doctor if you have ever been diagnosed with kidney or liver problems.
It can cause a sensation of restlessness or an inability to sit or stand still. This is most likely to occur within the first few weeks of treatment. You should tell your doctor if this happens to you.
- It may be more effective in some patients with depression who fails to respond to selective serotonin receptor inhibitors (SSRI) e.g. Fluoxetine.
- Monitor blood pressure (BP) frequently.
Loxetine Tablet related warnings
Loxetine 30 mg Tablet may cause excessive drowsiness and calmness with alcohol.
WEIGH RISKS VS BENEFITS
Loxetine 30 mg Tablet may be unsafe to use during pregnancy.
Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
Loxetine 30 mg Tablet is probably unsafe to use during lactation.
Limited human data suggest that the drug could represent a significant risk to the baby.
Loxetine 30 mg Tablet may make you feel dizzy, sleepy, tired, or decrease alertness. If this happens, do not drive.
Loxetine 30 mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Loxetine 30 mg Tablet may be needed. Please consult your doctor.
Dose adjustment is not recommended in patients with mild and moderate kidney disease.
Loxetine 30 mg Tablet is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor.
If you miss a dose of Loxetine 30 mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Frequently asked questions about Loxetine Tablet
Q. Is Loxetine a non-steroidal anti-inflammatory drug (NSAID)?
No. Loxetine is not a non-steroidal anti-inflammatory drug (NSAID). It belongs to the anti-depressant class of drugs, more specifically SNRI (Serotonin-Norepinephrine Reuptake Inhibitor). It works by increasing the levels of chemical messengers (serotonin and noradrenaline) in the nervous system.
Q. Is Loxetine a steroid?
No. Loxetine is not a steroid. It belongs to the anti-depressant class of drugs, more specifically SNRI (Serotonin-Norepinephrine Reuptake Inhibitor). It works by increasing the levels of chemical messengers (serotonin and noradrenaline) in the nervous system.
Q. Is Loxetine a blood thinner?
No. Loxetine is not a blood thinner. Blood thinners prevent the formation of harmful blood clots.
Q. Is Loxetine a stimulant?
No. Loxetine is not a stimulant. Stimulants are the medicines which activate the central nervous system.
Q. Is Loxetine a pain killer?
No. Loxetine is not a classical painkiller e.g. Non-Steroidal Anti-Inflammatory Drugs (NSAIDs).Duloxetine is used for the treatment of chronic pain conditions like neuropathic pain, diabetic neuropathy or fibromyalgia.
Q. Is Loxetine a tricyclic antidepressant (TCA)?
No. Loxetine is not a tricyclic antidepressant (TCA). It belongs to a class of anti-depressants called SNRIs (Serotonin-Norepinephrine Reuptake Inhibitors).
Q. Is Loxetine a benzodiazepine?
No. Loxetine is not a benzodiazepine. It belongs to a class of anti-depressants called SNRIs (Serotonin-Norepinephrine Reuptake Inhibitors). Benzodiazepines belong to the sedative-hypnotic class of drugs and include agents like diazepam, lorazepam, alprazolam etc.
Q. Is Loxetine a narcotic?
No. Loxetine is not a narcotic. It means it does not have habit-forming potential. Narcotics are the substance which can cause addiction and dependence.
Q. Is Loxetine a psychotropic?
Yes. A psychotropic is a medicine that affects mind, emotions, and behaviour. Loxetine, being an anti-depressant agent reduces the symptoms of depression and is a psychotropic agent.
Q. Can I take Loxetine if I have Hepatitis C virus infection?
Loxetine should be used with caution in patients with Hepatitis C virus infection. Cases of liver injury, including severe elevations of liver enzymes (>10-times upper limit of normal), hepatitis, and jaundice have been reported with Loxetine. Taking Loxetine increases the risk of liver toxicity and fatty liver in Hepatitis C virus-infected patients.<br>
Q. What is the peak plasma concentration [Cmax] of Loxetine?
The maximum plasma concentration [Cmax] of Loxetine is 6 hours post oral dose. Food taken with Loxetine may delay the time to reach the peak plasma concentration from 6 to 10 hours. This may marginally decrease the extent of absorption (approximately 11%).
Q. Can I take Loxetine with Vitamin D?
Yes. Loxetinecan be taken with vitamin D. It does not have any known interaction with Vitamin D.
Q. What is half life of Loxetine?
The elimination half-life of Loxetine ranges from 8 to 17 hours (mean 12 hours).
Q. Which is better in depression, Loxetine or fluoxetine?
Fluoxetine has not been found to be different in either tolerability or efficacy when compared with Loxetine in major depression. Loxetine is good for treating depression, anxiety and may help with chronic pain.
Q. Which is better Loxetine vs sertraline?
Loxetine and sertraline are found to be equally effective in the treatment of Major Depressive Disorder (MDD). Certain symptoms like agitation and anxiety are reduced better by sertraline. Loxetine has been found to be better than sertraline for neuropathic pain.
Q. Which is better for chronic pain, Loxetine or pregabalin?
In patients with fibromyalgia Loxetine is found to be better than pregabalin in reducing depressed mood. Pregabalin is better in reducing fatigue. Loxetine and pregabalin generally provide equally comparable pain relieving efficacy in the treatment of diabetic peripheral neuropathic pain (DPNP).
Q. Which is better Loxetine or fluoxetine?
Loxetine has been found to be better for the treatment of chronic pain than Fluoxetine. Fluoxetine is good for treating depression and anxiety.
Q. Which is better for depression, Loxetine or mirtazapine?
Currently, there is not enough information to firmly recommend one antidepressant over another. However, both these drugs have been found to be safe and efficacious in the treatment of depression.
Q. Which is better for depression, Loxetine or venlafaxine?
Currently, there is not enough information to firmly recommend one antidepressant over another. Many doctors favour Loxetine over venlafaxine when pain conditions coexist with depression.
Q. Is Loxetine a barbiturate?
No. Loxetine is not a barbiturate. Barbiturates belong to the Sedative-Hypnotic class of drugs and are likely to have abuse potential.
Q. When to take Loxetine?
Loxetine can cause difficulty in sleep (insomnia). Hence, it is advised to be taken in the morning than at night.
Q. When does Loxetine start working?
Usually, the action of Loxetine takes about three to four weeks to appear. Do not discontinue the therapy in between, thinking that it is not effective.
Q. How much dose of Loxetine can produce overdose?
Overdose can occur at a doses as low as 1000 mg. Signs and symptoms of overdose (duloxetine alone or in combination with other medicinal products) included somnolence, coma, serotonin syndrome, seizures, vomiting and tachycardia.
Q. How does Loxetine work in urinary incontinence?
Loxetine is thought to work by interfering with certain chemicals (called serotonin and noradrenaline) that are used within the nerves that send messages to your pelvic floor muscles. This helps the muscles around the bladder outlet to contract more strongly, and this in turn controls the flow of urine and helps to prevent any leakage.
Q. Can I take Loxetine with amitriptyline?
It is better to avoid Loxetine and amitriptyline together. It can increase the risk of a serious condition called the serotonin syndrome, with symptoms such as confusion, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea.
Q. Can I take Loxetine with sertraline?
It is better to avoid Loxetine and sertraline together. It can increase the risk of a serious condition called the serotonin syndrome, with symptoms such as confusion, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea.
Q. Can I take Loxetine with tramadol?
Loxetine and tramadol together can increase the risk of a serious condition called the serotonin syndrome, with symptoms such as confusion, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea. Please inform your doctor if you are taking any of these medicines before coming to him.
Q. Can I take Loxetine with bupropion?
Bupropion can cause inhibition of metabolism of Loxetine in the body, resulting in toxic effects of Duloxetine. The concomitant use of these two drugs can result in seizures. Mention it to your doctor if you are taking any of these medications from before.
Q. Which is better in diabetic neuropathy, duloxetine or pregabalin?
In patients with fibromyalgia, Loxetine is found to be better than pregabalin in reducing depressed mood. Pregabalin is better in reducing fatigue. Loxetine and pregabalin generally provide equally comparable pain relieving efficacy in the treatment of diabetic peripheral neuropathic pain (DPNP).
Q. Can Loxetine get me high?
No. Loxetine does not cause a high. It does not create a feeling of euphoria and has no recreational potential.
Q. Can I use Loxetine for arthritis?
Loxetine is not approved for the treatment of arthritis. It is used in the treatment of depression, anxiety disorder, diabetic nerve disease, neuropathic pain and overactive urinary bladder.
Q. Can I use Loxetine for sciatica?
No, Loxetine is not approved for the treatment of sciatica. It is used in the treatment of depression, anxiety disorder, diabetic nerve disease, neuropathic pain and overactive urinary bladder.
Q. Can I use Loxetine for obsessive-compulsive disorder (OCD)?
Obsessive-compulsive disorder (OCD) is a type anxiety disorder. It is approved for the treatment of obsessive-compulsive disorder. Research studies suggest that Loxetine may provide a significant reduction in symptoms for patients with obsessive-compulsive disorder.
Q. Can I use Loxetine for hot flashes?
No. Loxetine is not approved for use in hot flashes. It may be used in the treatment of depression in postmenopausal women suffering from menopausal vasomotor symptoms (hot flashes, night sweats) and insomnia.
Q. Can I use Loxetine for headaches?
No, Duloxetine is not approved for use in headaches. It is used in the treatment of depression, anxiety disorder, diabetic nerve disease, neuropathic pain and overactive urinary bladder.
Q. Can I use Loxetine for a migraine?
No. Loxetine is not approved for use in a migraine. It is used in the treatment of depression, anxiety disorder, diabetic nerve disease, neuropathic pain and overactive urinary bladder.
Q. Can I use Loxetine for chronic pain?
Loxetine is approved for the treatment of chronic pain states including neuropathic pain (nerve pain) associated with Diabetes Mellitus and fibromyalgia.
Q. Can I use Loxetine for nerve pain?
Yes. Loxetine is approved for use in nerve pain or neuropathic pain conditions, most commonly seen in patients suffering from Diabetes Mellitus.
Q. Can Loxetine raise blood sugar levels?
No. Loxetine may affect blood sugar levels. If you are diabetic and notice a change in the results of your blood or urine sugar tests, check with your doctor.
Severely interacts with other drugs like
Taking Loxetine with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Medicines with composition Thioridazine: R Zin, T Zine, Thioril, Tridaz, Multizine, Ridazin, Delnil, Thiolent, Zeneril, Sychozine, Psyril, Melleril, Tensaril, Repoise, Thiorus, Melozine
Medicines with composition Lithium: Psycolith, Cartil, A Lith, Likon, Lidep, Lithocent, Lisalt, Lithocap, Carbolith, Hethium, Zecarb, Lalithium, T Lith, Tricab, Lithicab, Lithoril, Lithosun, Olith, Monolith, Lithic, Elcab, Lithosan, Lithochik, Lithonex, Trilith, Litholite, Lithox, Manicarb, Lithowel, Lithex, Litca, Movalith, Litman, LI, Lithon, Intalith, Litholent
Medicines with composition Citalopram: Olarc, Citopam, Cetadep, Topdep, Celica, Citalomine, Citalent, Citola, Cytop, Madam, Citalin, Citara, Lopram, Ciprexa, Citox, C Pram, Celepra, Citalopam, Mahapram
Medicines with composition Flecainide: Flecarite
Medicines with composition Dapoxetine: Actinex, DA Sutra, Stay Tal, Dapoxy, Dapnex, Duraject, Appynite, Dejac, Xydap, Dapox, Ejalong, Prilyxet, Duralast, Justinex, Kutub, Asenven, Ultimale, Dapolast, Sensape, Viglast, EJ, Sustinex, Duragain
Medicines with composition Escitalopram: Kopram, Ecit, Escnx, Esitopa, Madito, Citolex, Elcit, Escivi, Esetinol, Esmood, Solopram, Sancita, Emjoy, Recita, Jovail, Oxpram, Cit, Anipram, Cipralex, Articalm, SC Talo, Sri, Serosez, Depitame, Deplam S, ES OK, C-Pram S, Szetalo, Feliz-S, Nexito, Renopram, Sitaram, Citajoy, Cilentra, Esopam, Deptune, Esciram, Escipra, Esitor, Escitlocad, Elorpax, Stalopam, Citapure Forte, Taloprex, Citofast, Estilo, Jopram, Cipam S, Escalate, Censpram, Pridep S, Celor S, Esna, Citopil, S-Celepra, Escer, Estajoy, Astal, Citel, Jovil, Elcita, Joycom, Galop Plus, S-Citapad, Eloprax, Excita, Lexadep, Desilam, Escytop, Coxito S, Citapure, Ambulax AD, Ezeepam, Essita, Pracidep S, Citaford S, Espam, Estalo, Lifodep Plus, Rexipra, Escizen, Estomine, S Vocita, Escigress, Firsito, Dexanil, Geripram, Xefexor, Prasilife, Esciptal, Prasilex, Galop, Topdep S, Ecitel, Delicita, Escitapax, Citapad, Anxiset E, Talo S, Esredep, Escitalent, Esdep, S Citadelm, Cita S, Esfany, Escance, Esopram, Estomine Zee, Dexanil Plus, Ava, Citalop S, Esci, Strutee-Pam, Esipram, Dipwell, Estadep, Esetalo, Esjoy, Depranex, Xitpram, Halotil, Escitus, Esnax, Taloz, Escada, Yellowpam, Escetalax, Maxcito, Questa, Stalopress, Estop, Talosrin, Escirise
Medicines with composition Fluoxetine: Flotin, Serodep, Fluxen, Fludep, Fluty, FT, Depilox, Bydep, Afzot, Ulaxy, Flurix, Tune, Foxe, Zotin, Fluxin, Deptol, Depten, Biodep, Flutex, Hidac, Flumax, Cylenc F, Flunil, Fludac, Salidep, Tritin, Fadep, Dawnex, Flutee, Acodac, Theoxetin, Arkadep, Floxin, Barozac, Zexto, Fudis, Nuzac, Fluoxet, Dedep, Oxefil, Serraflam, Prodep, Flutop, Flumod, Vetodep, Flood, Fluze, F Tin, Depnil, Flunat, Flucer, Inaday, Fluzin, S.R.B., Flutin, Nodep, Exidep, Floxiwave, Floatin, Fluden, Cozac, Elemod, Cyclotin, Flumusa, Mentol, Flonol, Fluron, Flox, Fluxater, Flutine, Neurozac, Prodep LA, Fluox, Dimrid, Fluz OD, Luxet, Flumeg, Zedep, Exiten, Noc, Depzac, Flunam, Flucap, Flame, Lauxine, Persona, Fludawn, Depextine, Depcure, Fluxy, Griloc, Normatine, Trizac, Faxtin, F-20, Fastgen, Strutee, Fly
Medicines with composition Sertraline: Zosert, Sernit, Taline, Biosert, Pifser, Yline, Mares, Serwal, Setalin, Setrakon, Bioserene, Sertax, Sertosh, Aniser, Daxid, Lincer, S R T, Serly, Serzest, Senta, Serozac, Lindep, Sertacad, Nash, Sertee, Seroflex, Zotral, Sertagress, Serlin, Sertin, Sertop, Zentalin, Serbest, Seronorm, Sertaj, Zanserta, Steel, Zert OD, Serta, Stalin, Sertil, Serenata, Sen, Serne, Serene, Sertima, Sate, Visert, Inosert, Serpan, Sertrax, Sedeptine, Eccite, Retalin, Episod, Actiser, Obzin, Setra, Mentolift, Santa, Sertakem, Sertawin, Setral, Serotra, Xsert, Normaset, Sentral, Misol, Serdep, Serena, Assert, Osmoset, Serline, Ser, Sermind
Medicines with composition Propafenone: Pradil
Medicines with composition Darunavir: Virem
Medicines with composition Fluvoxamine: Boxamine, Voxinix, Uvox, Voxidep, Voxazen, Voxamin, Psyvoxin, Fluxam, Sorest, Fluvoxin, Fluvo, Frext, Fluvator, Fluvoxine, Ocivox, Arkavoxin, Revilife, Fmine, Fluvaris, Voximin, Flumin, Vanvox, Obsace
Medicines with composition Indinavir: Indivan
Medicines with composition Paroxetine: Leparox, Prx, Paromec, Madotine, Parolyst, Parox, Baxidep, Psypro, Pirotin, Paropex, Depaxil, Patriot, Xet, Parocen, Paroxee, Pxt, Praxet, Parot, Paxidep, Pxn, Emoxet, Paxiford, XL Paro, Paradise, Pexep, Petin, Patroxta, Mopart, Paxit, Panex, Praxo, Paronet, Paroxet, Xepar, Paroxta, Raxit, Oxitine PR, Paxgem, Paro, Stamna P, Parotin, Pari, Depxet, Paxi, Pexpen, Paxotus, Onbixin, Xodep, Paxonil, Fordep, Paxquit, Senoxetin, Parona, Peximer, Parogen, Tinpax, Oxitine
One of the following vendor pharmacies will deliver Loxetine 30mg Tablet: WAD, HMP, PHC, RSS, KIS, PRC, TFP, SPD, ZPR, DFP, TAT, GTK, IAD, HPC, HTS, HNP, SRG, ATP, EAN, HAT, BHS, DYG, VRS, ASP, AYN, BNT, HSM, MPC, HGI, 4IT, SNH, BMJ, WHL, VDH, MAX, HSP, BLE, SYN, HWI, CRN, RPP, LCC, GMA, ZEL, GHR, SGC, TSS, GPP, JVO, DVH, AWS, DLP, SGH, RPI, HIP, SHC, NXG, INC, DYL, SCH, PHN, MBP, RGH, JSL, EQN, DPL, AYM, OHM, SHD, PRN, DGN, ARD, BIO, TRP, CMC, IMC, UHP, WSI, AFT, EMB, JBT, PRL, JVN, LMS, DRA, YMI, OIP, GLM, SWT, NDP, PTP, NVL, MDO, 9MM, MDH, WPL, OLT, RHW, BDI, PLT, GPT, SVH, ANT, VSL, AYU, KHC, BSN, NTB, SWA, MAP, UMP, RUS, RDH, AVS, KHH, BBS, BBN, DHR, QLF, CLT, NVY, KMC, DPP, DHP, DZY, PWN, AAY, JJE, 1MH, ABP, BAP, SWP, HPP, SSI, KHD, AGT, LHP, NNP, CHP, GNC, KNH, JIV, ENP, NAS, VOP, MAK, AAR, AXM, SDM, AVB, RHL, HZF, RKS, LHA, OBS, HEX, SDE, XMX, HLT, AMR, RDR, EPS, RWP, BDN, STS, PPR, FGH, BHM, RSA, GTC, HBV, SLN, SVS, PRT, VSC, MAM, PVP, NSL, ESY, FRM, PTI, VNS, KLC, APS, SMS, QTM, BJP, ZVP, SBA, NEO, SCP, NTL, EVP, TOM, GDA, CPK, AVL, ALC, THP, BGS, BHP, MKT, HCP, MLC, BRC, ANP, STA, SMN, AMH, SJP, SNG, UVD, MSD, PNT, OWP, DAO, SSA, GLD, ATL, USF, EEC, MKS, VHP, IPL, BLS, VTR, BNA, BAL, SAF, PMA, BLP, SBL, GBL, BTM, SSS, VJS, JHC, GEO, BHA