Klomin 50mg Tablet is a tricyclic antidepressant. It is used in adults to treat obsessive-compulsive disorder (OCD). It also treats muscular weakness (cataplexy) associated with repeat attacks of sleepiness (narcolepsy) and can manage depression that is unresponsive to other medicines.

Klomin 50mg Tablet works by increasing the levels of chemical messengers in the brain that stabilizes and enhances the mood. It is better to take it before bedtime because it can make you feel sleepy. It can be taken with or without food, but you should take it at a fixed time each day for better efficacy. The dose and duration will be decided by your doctor so that you get the right amount to control your symptoms. If you have missed any dose, take it as soon as you remember. Do not skip any dose and finish the full course of treatment even if you feel better. This medication must not be stopped suddenly without talking to the doctor. Your dose may be modified or gradually decreased before stopping the medication.

The most common side effects of this medicine include indigestion, loss of appetite, dryness in the mouth, nausea, and constipation among others. It may also cause dizziness and drowsiness, do not drive or do anything that requires mental focus until you know how this medicine affects you. To lower the chances of dizziness, rise slowly if you have been sitting or lying down. It may also lead to weight gain in some people. Most of the common side effects tend to be mild and temporary. Your doctor may be able to suggest ways of preventing or reducing side effects if they bother you or do not go away. Serious side effects associated with this medicine are rare.

Before taking this medicine, it is important to tell your doctor if you are taking or have recently taken any other medicines for the same or any other diseases. Pregnant and breastfeeding women should take this medicine with proper consultation and caution. This medicine is not addictive, but you can experience additional side effects (withdrawal symptoms) if you stop taking it suddenly. If you notice any sudden mood change or get suicidal or self-harm thoughts, you must consult the doctor without delay. Also, remember to take this medicine strictly as advised by the doctor as an overdose of this medication may lead to a serious health emergency.

Uses of Klomin Tablet

Obsessive-compulsive disorder
Depression
Treatment of Narcolepsy (Uncontrollable daytime sleepiness)

Benefits of Klomin Tablet

In Obsessive-compulsive disorder

Obsessive-compulsive disorder (OCD) is a disorder that affects mental health. People may develop a cycle of obsessions and compulsions, irrespective of age. Obsessions are unwanted, repeated thoughts, images, or urges that trigger excessively distressing feelings. Klomin 50mg Tablet helps relieve symptoms of obsessive-compulsive disorder by increasing the level of a chemical called serotonin in your brain. It has fewer side effects than other medicines and is normally taken once a day. Keep taking the medicine until your doctor advises you to stop.

In Depression

Klomin 50mg Tablet is thought to work by affecting the balance of certain chemicals (such as serotonin) in the brain. It helps improve mood and feelings of wellbeing, relieve anxiety and tension, help you sleep better, and increase your energy level. It is used to treat depression that is unresponsive to other medicines. You need to take it regularly as it is prescribed for it to be most effective and should not stop taking it suddenly.

In Treatment of Narcolepsy (Uncontrollable daytime sleepiness)

Narcolepsy is a sleep disorder that causes excessive daytime drowsiness. The affected person may experience excessive sleepiness, sleep paralysis, hallucinations, and in some cases episodes of cataplexy (partial or total loss of muscle control). Klomin 50mg Tablet stimulates the brain and makes you fully awake. It also relieves these abnormal symptoms and regulates the sleep cycle. This restores normal sleeping habits and improves your quality of life. You will feel more energetic and will be able to perform better in your daily activities.

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Side effects of Klomin Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Klomin

Drowsiness
Urinary incontinence
Altered libido
Constipation
Dryness in mouth
Aggravation of depression
Agitation
Anxiety
Blurred vision
Delirium (acute confusional state)
Dizziness
ECG changes
Erectile dysfunction
Fatigue
Headache
Hypomania
Increased appetite
Nausea
Orthostatic hypotension (sudden lowering of blood pressure on standing)
Palpitations
Ringing in ear
Sleep disorder
Sweating
Tremors
Weight gain
Confusion
Hallucination
Mania
Micturition disorders
Altered blood sugar level

How to use Klomin Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Klomin 50mg Tablet is to be taken with food.

How Klomin Tablet works

Klomin 50mg Tablet is a tricyclic antidepressant. It increases the levels of chemical messengers in the brain that help in regulating the mood and treat depression.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Klomin 50mg Tablet.

Pregnancy

CONSULT YOUR DOCTOR

Klomin 50mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Klomin 50mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

UNSAFE

Klomin 50mg Tablet may cause side effects which could affect your ability to drive.
If you feel dizzy, tired, have blurred vision, have difficulty concentrating, or have other effects such as confusion, disorientation or your depression gets worse with Klomin 50mg Tablet, do not drive.

Kidney

CONSULT YOUR DOCTOR

There is limited information available on the use of Klomin 50mg Tablet in patients with kidney disease. Please consult your doctor.
Caution should be exercised in patients with underlying kidney disease. Regular monitoring of kidney function test is advised while you are taking this medicine.

Liver

CAUTION

Klomin 50mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Klomin 50mg Tablet may be needed. Please consult your doctor.
Regular monitoring of liver function tests is advisable when you are taking this medicine.

What if you forget to take Klomin Tablet?

If you miss a dose of Klomin 50mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

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Quick tips

It may take 4 to 6 weeks for Klomin 50mg Tablet to start working. Keep taking it as prescribed.
It may cause sleepiness. Take it at bedtime and do not drive or do anything requiring concentration until you know how it affects you.
Avoid consuming alcohol when taking Klomin 50mg Tablet as it may cause excessive sleepiness.
Monitor your weight during the treatment as this medicine can cause weight gain and increased appetite.
Talk to your doctor if you notice sudden mood changes or develop suicidal thoughts.

Fact Box

Chemical Class

Dibenzoxepin Derivative

Habit Forming

Therapeutic Class

NEURO CNS

Action Class

Tricyclic antidepressants

Interaction with drugs

Taking Klomin with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Linezolid

Brand(s): Lizolan, Lidoford, Zenlid

Life-threatening

Moclobemide

Brand(s): Trima, Rimarex, Morex

Life-threatening

Moxonidine

Brand(s): Moxicheck, Moxonex, Unsym

Life-threatening

View all interactions

Patient concerns

I have Obsessive compulsive Disorder. Prescribe the medication.

Dr. Deepak Kumar Soni

Ayurveda

Hi Kindly share your symptoms of your Problem

Sir, I wont to take best medicine of Ayurveda for obsessive compulsive disorders(Depression)

Dr. Ankur Kumar Tanwar

Ayurveda

Use brahmi granules and jatamansi vati ,

What is obssesive compulsive disorder

Dr. Jyoti Kapoor Madan

Psychiatry

Obsessive-Compulsive Disorder (OCD) is a common, chronic and long-lasting disorder in which a person has uncontrollable, reoccurring thoughts (obsessions) and behaviors (compulsions) that he or she feels the urge to repeat over and over. It's a neurochemical disturbance in brain and worsens due to stressful environment. OCD is typically treated with medication, psychotherapy or a combination of the two.

Hello Dr. I am suffering from sometime extreme anger sometime while talking unwanted thought I can't trust on anybody .I feel doubt about everyone like they used me .I don't talk my old frnds also feeling little depression and very very low confidence . currently I am taking vilazine20 and my add lurasid 40 ten days ago.now little improvement bt I am not happy trying to being happy bt cant.help me

Dr. Jyoti Kapoor Madan

Psychiatry

You seem to have anxiety with obsessions especially obsessive doubt. Vilazodone may need to be increased as 20 mg isn't usually adequate for obsessive symptoms. Obsessive-Compulsive Disorder (OCD) is a common, chronic and long-lasting disorder in which a person has uncontrollable, reoccurring thoughts (obsessions) and behaviors (compulsions) that he or she feels the urge to repeat over and over. It's a neurochemical disturbance in brain and worsens due to stressful environment. OCD is typically treated with medication, psychotherapy or a combination of the two. Treatment duration depends upon the intensity and frequency of episodes and may be needed throughout life.

Main problem : I keep feeling too sleepy throughout the day. I have so many things to do related to my career, family and social life but this problem has been consuming most of my quality time, brings down my energy making me too less productive. I have been reading about this thing over Internet and what I can figure out myself is that my problem seems to be too close to Narcolepsy.

Dr. Jyoti Kapoor Madan

Psychiatry

Narcolepsy is sudden uncontrollable bout of sleepiness. Often sleep problems are due to poor quality of night time sleep. You may go for a sleep study or polysomnography to identify sleep related issues and tackle the problem easily.

palpitation tachycardia hypertension loud snoring daytime sleepiness

Dr. Jyoti Kapoor Madan

Psychiatry

Anxiety is the result of a hyperarousal state of nervous system due to a low threshold for threat perception. In simpler words, it's an ongoing flight or fight response. It can elicit a neuro-hormonal response understood as Flight or Fright reaction kicking in physiological cascade of symptoms ranging from palpitations, tachycardia, breathlessness, increased bowel movement, increase frequency of urination, dizziness, muscle tension or pain, trembling, dizziness, blurring of vision to restlessness, confusion and fainting spells. Chronic stress causes prolonged anxiety response with the consequences of slowed cognition , lack of concentration, headaches, fluctuations in blood pressure, irritable bowel syndrome with persistent Bowel movement issues and increased wear and tear of body tissues. Identifying your stressors, learning to deal with them, de stressing regularly by doing something that makes one feel good, yoga and meditation are some non pharmacological strategies to deal with it. If the condition is persisting for a long time, it's better to see a psychiatrist.

User feedback

What are you using Klomin Tablet for?

Obsessive-com*

100%

*Obsessive-compulsive disorder

FAQs

Q. Can Klomin 50mg Tablet cause impotence?

Yes, Klomin 50mg Tablet can cause impotence. Both men and women may experience decreased sexual desire and inability to have an organsm. In males, difficulty in maintaining erection (impotence) or painful ejaculation may be observed. You should consult your doctor immediately if you face any such problems while taking Klomin 50mg Tablet.

Q. Is Klomin 50mg Tablet safe?

Yes, Klomin 50mg Tablet is safe to use if taken in the dose and duration prescribed by the doctor. Klomin 50mg Tablet is a medicine that treats Obsessive-Compulsive Disorder (OCD), stabilises mood and behavior. It restores the chemical imbalance in the brain and creates a feeling of well being.

Q. What are the side effects of Klomin 50mg Tablet?

Klomin 50mg Tablet may cause side effects like difficulty or inability to pass urine, altered libido, constipation, dryness in mouth, ejaculation disorder, indigestion and sleepiness. Please consult your doctor if these side effects worry you. The doctor may suggest ways to treat or prevent them.

Q. What happens if I take an overdose of Klomin 50mg Tablet?

If you have taken an overdose of Klomin 50mg Tablet, you may experience symptoms such as drowsiness, restlessness, agitation and delirium (disturbed state of mind with restlessness and mental confusion). You may also experience severe sweating, fast heartbeat, feeling of faint, seizures (fits), and you may even go into a state of coma. Immediately consult your doctor and seek medical help if you think you have taken too much of this medicine.

Q. If I am feeling better, can I stop taking Klomin 50mg Tablet?

No, do not stop taking Klomin 50mg Tablet suddenly even if you are feeling better as it may worsen your condition and also cause withdrawal symptoms such as dizziness, nausea, vomiting, headache, weakness, sleep problems, fever, and irritability. Continue taking Klomin 50mg Tablet for the duration as prescribed by your doctor to get maximum benefit. If any of the side effects are bothering you, consult your doctor. In case you have completed your course of treatment, your doctor will reduce your dose gradually before taking you off this medicine completely.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Stahl SM, editor. Clomipramine. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 129-35.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 298-300.
Clomipramine hydrochloride. Whitby, Ontario, Canada: Patheon Inc.; [revised Jun. 2014]. [Accessed 22 Mar. 2019] (online) Available from:
Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 20 Mar. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 22 Mar. 2019] (online) Available from:

Manufacturer/Marketer address

12th Milestone, Mathura Road, Faridabad – 121 003

Country of origin: India

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