Medicine Overview of Istavel Tablet
Uses of Istavel Tablet
Istavel 100mg Tablet is used in the treatment of type 2 diabetes.
Side effects of Istavel Tablet
Headache, Upper respiratory tract infection, Hypoglycaemia (Low blood sugar level) in combination with insulin or sulphonylurea, Nasopharyngitis.
How to use Istavel Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. It can be taken with or without food, but it is better to take Istavel 100mg Tablet at a fixed time.
How Istavel Tablet works
Istavel 100mg tablet increases the amount of insulin released by the pancreas, which in turn lowers the blood glucose levels.
In Depth Information on Istavel Tablet
Expert advice for Istavel Tablet
- If you experience stomach pain, nausea or vomiting, stop taking Istavel and inform your doctor immediately.
- Istavel is a well tolerated and safe anti-diabetic drug and does not cause very low blood sugar levels and weight gain.
- Take Istavel with water at any time of the day with or without food. Do not chew or crush the tablets.
- You would be at an increased risk of hypoglycemia (low blood sugar level) when insulin and sulfonylureas are also given along with, a dose adjustment may be needed. Do not change the dose yourself.
- Inform your doctor if you have ever been diagnosed with kidney or liver problems.
- Istavel can increase the risk of acute pancreatitis (swelling of your pancreas) which can be life threatening. Tell your doctor if you have a history of pancreatitis, gallstones, or alcohol intake.
- If you experience severe joint pain or allergic reactions (skin rash, swelling of the face, lips, tongue and throat which causes difficulty in breathing), stop taking the medicine and inform your doctor.
- Tell your doctor if you are pregnant or planning to get pregnant or breastfeeding.
Special precautions for Istavel 100mg Tablet
Taking Sitagliptin with alcohol may affect blood glucose levels in patients with diabetes.
Istavel 100mg Tablet is probably safe to use during pregnancy.+more
Animal studies have shown low or no adverse effect on the foetus, however, there are limited human studies. Please consult your doctor....
Animal studies have shown low or no adverse effect on the foetus, however, there are limited human studies. Please consult your doctor.
Istavel 100mg Tablet is probably safe to use during lactatio+more
n. Limited human data suggests that the drug does not represent a significant risk to the baby....
Your ability to drive may be affected if your blood sugar is+more
low or high. If this happens, do not drive....
Istavel 100mg Tablet should be used with caution in patients+more
with kidney disease. Dose adjustment of Istavel 100mg Tablet may be needed. Please consult your doctor....
Istavel 100mg Tablet is probably unsafe to use in patients w+more
ith liver disease and should be avoided. Please consult your doctor....
Severely interacts with other drugs like
Decmax 4mg Tablet, Decamycin 4mg Injection, Pericort 4mg Tablet, Depo Medrol 40mg/ml Injection
If you miss a dose of Sitagliptin, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Frequently asked questions for Istavel 100mg Tablet
Frequently asked questions for Sitagliptin
No, Istavel is not a statin. Istavel is an antidiabetic drug and it belongs to the class of dipeptidyl peptidase-4 (DPP-4) inhibitors. while Statin is a class of lipid-lowering drugs.
Istavel is safe to use when taken for a prescribed duration in the dose advised by a doctor. However, you can experience some common side effects at the prescribed dose also, like a headache, upper respiratory tract infection, nasopharyngitis and hypoglycemia (Low blood sugar level) when used along with insulin or sulphonylureas.
No, Istavel is not a blood thinner. Istavel is an antidiabetic drug and it belongs to the class of dipeptidyl peptidase-4 (DPP-4) inhibitors.
Q. Is Istavel better than teneligliptin?
Istavel and Teneligliptin belong to the same class of drugs. They have a similar mechanism of action and efficacy to control blood sugar levels. However, Teneligliptin is safe to use in patients with underlying kidney disease while a dose adjustment of Istavel is needed in patients with moderate to severe kidney disease.
Do not stop taking Istavel until advised by your doctor as this can lead to a sudden rise in your blood sugar levels. However, in case you experience stomach pain while taking Istavel, immediately stop taking it and inform your doctor. Follow all directions given to you by your doctor carefully.
Q. How is Istavel different from dapagliflozin?
Both Istavel and Dapagliflozin are antidiabetic drugs, but they work in different ways. Dapagliflozin is seen to be more effective in controlling blood sugar levels and helps in weight loss while Istavel is weight neutral. They also differ in their side effect profile as the use of Istavel is associated with nausea, nasopharyngitis, and pancreatitis while Dapagliflozin commonly causes urinary and genital tract infections.
Q. How is Istavel different from vildagliptin?
Istavel and Vildagliptin belong to the same class of anti-diabetic drugs. However, Vildagliptin is seen to be more effective in controlling blood sugar levels with less fluctuations compared to Istavel. But Vildagliptin is to be taken twice a day while Istavel is taken once a day.
Istavel is an antidiabetic medicine and its interaction with other drugs is very limited. Istavel itself is less likely to cause hypoglycemia (low blood sugar), however, when taken with other anti-diabetic medicines, the risk increases. Also, Istavel can increase the blood levels of digoxin which can lead to more side effects with digoxin.
Q. How is Istavel different from pioglitazone?
Istavel and pioglitazone are antidiabetic drugs with different actions and have different side effect profile. Pioglitazone is seen to cause edema (water retention is tissues), weight gain and can increase the risk of heart failure. On the other hand, use of Istavel is seen to be associated with pancreatitis.
Istavel along with metformin is used off-label for the treatment of polycystic ovarian syndrome (PCOS) as it has shown efficacy in this condition in some clinical studies. However, its use in PCOS is yet not approved. Please consult your doctor.
Q. Can I use Istavel with rosuvastatin?
Yes, Istavel can be used with rosuvastatin. No drug-drug interactions or any change in side effect profile has been reported compared to when they are used alone.
Q. How is Istavel different from voglibose?
Both Istavel and voglibose are antidiabetic drugs but they belong to different classes and have different side effect profiles. Voglibose commonly causes rash, flatulence, abdominal pain and diarrhea whereas Istavel is commonly seen to cause headache, upper respiratory tract infection and hypoglycemia when taken with other antidiabetic drugs.
Q. How is Istavel different from empagliflozin?
Both Istavel and Empagliflozin are antidiabetic drugs, but they work in different ways. Empagliflozin is seen to be more effective in controlling blood sugar levels and helps in weight loss while Istavel is weight neutral. They also differ in their side effect profile as the use of Istavel is associated with nausea, nasopharyngitis, and pancreatitis while Empagliflozin commonly causes urinary and genital tract infections.
Q. What is the difference between Istavel and canagliflozin?
Both Istavel and Canagliflozin are antidiabetic drugs, but they work in different ways. Canagliflozin is seen to be more effective in controlling blood sugar levels and helps in weight loss while Istavel is weight neutral. They also differ in their side effect profile as the use of Istavel is associated with nausea, nasopharyngitis, and pancreatitis while Canagliflozin commonly causes urinary and genital tract infections.
Q. How is Istavel different from liraglutide?
Both Istavel and liraglutide are antidiabetic drugs but they work in different ways. Liraglutide is more effective in controlling blood sugar levels and also help to lower body weight compared to Istavel which is weight neutral. Moreover, liraglutide is available as an injectable whereas Istavel is an oral medication.
Q. Can I take Istavel with Metformin?
Yes, Istavel can be taken with Metformin. It is a good add-on treatment if the blood sugars are very high even after taking Metformin and the risk of low blood sugar levels (hypoglycemia) does not become very high when they are taken together. However, a dose adjustment of the two may be needed.
Yes, you can take Istavel with insulin. Using them together can lower the insulin dose and decrease the risk of hypoglycemia (low blood sugar levels).
Q. How is Istavel different from Glipizide?
Both Istavel and Glipizide are antidiabetic drugs but they belong to different classes and have different side effect profiles. Glipizide commonly causes hypoglycemia and weight gain while Istavel is commonly associated with a headache and nasopharyngitis.
Q. How is Istavel different from Glimepiride?
Both Istavel and Glimepiride are antidiabetic drugs but they belong to different classes and have different side effect profiles. Glimepiride commonly causes hypoglycemia and weight gain while Istavel is commonly associated with a headache and nasopharyngitis.
Q. Can I take Istavel with Glipizide?
Yes, Istavel can be taken with Glipizide. Both are antidiabetic drugs but they work in different ways. When taken together, they can help in better control of blood sugar levels. However, the risk of low blood sugar levels (hypoglycemia) can increase if the dose of glipizide is not adjusted.
Q. Is it beneficial to use Istavel with liraglutide?
No, it is not advisable to take Istavel with Liraglutide. Both work by increasing the level of incretin hormones and can be expected to have a better efficacy but, there could also be an increased risk of side effects like pancreatitis when they are used together.
Use of Istavel is not associated with either weight loss or weight gain. It is weight neutral.
Istavel can lower blood sugar level (hypoglycemia). However, it happens more often if you delay or miss your food, do more than routine exercise, drink alcohol or take other antidiabetic medicine along with. Be cautious of the symptoms of hypoglycemia and always keep glucose tablets or honey or fruit juice with you. Regular monitoring of blood sugar levels is important.
Istavel belongs to the group of drugs called incretins which have been associated with pancreatic cancer in some clinical studies. However, a definite evidence is missing, so, it is advisable to talk to your doctor regarding the same.
Yes, constipation is an uncommon side effect seen with the use of Istavel. Taking a fiber rich diet and plenty of water can help in relieving constipation.
Yes, somnolence (sleepiness) has been reported with the use of Istavel. Also, there could also be an increased risk of hypoglycemia (very low blood sugar levels) when used with other antidiabetic drugs which can make you feel dizzy. Be careful while driving or when operating a machine.
Istavel is not known to cause itching. However, in case you develop an allergic reaction to Istavel or any of its ingredients, you may have symptoms of itching, redness or swelling of the mouth, lips, tongue or throat. Immediately stop taking the medicine and inform or visit a doctor.
No, the use of Istavel is not seen to be associated with dry mouth.
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