Isentress 400mg Tablet

MSD Pharmaceuticals Pvt Ltd

Composition for Isentress 400mg Tablet

iconPrescription Required

Primarily used for

60 tablets in 1 bottle

Medicine Overview of Isentress Tablet


Uses of Isentress Tablet

Isentress 400mg Tablet is used in the treatment of HIV infection.

Side effects of Isentress Tablet


Insomnia (difficulty in sleeping), Fatigue, Headache, Nausea, Dizziness, Muscle pain, Diarrhoea, Increased liver enzymes.


How to use Isentress Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. It can be taken with or without food, but it is better to take Isentress 400mg Tablet at a fixed time.

How Isentress Tablet works

Isentress 400mg tablet prevents the multiplication of HIV virus in human cells. Thus stops the HIV virus from producing new viruses.

In Depth Information on Isentress Tablet

Expert advice for Isentress Tablet

  • Do consult your doctor before taking raltegravir if you have phenylketonuria (a serious hereditary disorder), a medical history of depression or any psychiatric illness, severe liver disorders or muscle disorders (myopathy or rhabdomyolysis).
  • Contact your doctor immediately if you notice stiffness, pain and difficulty in movement of joints or unexplained muscle pain, weakness and tenderness or notice signs of any infection such as fever while on treatment with raltegravir.
  • Avoid taking antacids containing aluminum or magnesium within 2 hours before or 2 hours after you take raltegravir.
  • Do not operate machines, drive or cycle if you feel dizzy after taking raltegravir.
  • Raltegravir does not prevent the spread of HIV virus to others through blood or sexual contact. Take the required precautions to prevent transmission.
  • Continue taking raltegravir even if you feel well, as skipping the medicine may worsen your condition and may lead to resistance to treatment.
  • You must be aware that your body fat may increase or move to different areas of your body such as your breasts and upper back while on raltegravir therapy.
  • Tell your doctor if you are or planning to become pregnant or are breastfeeding. You must receive proper treatment for HIV to avoid passing of the infection to your baby.
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Special precautions for Isentress 400mg Tablet
Interaction with alcohol is unknown. Please consult your doctor.
Isentress 400mg Tablet may be unsafe to use during pregnancy.

Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
Isentress 400mg Tablet should be used with caution during lactation. Breast feeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.

WHO guidelines recommends that all nursing mothers in developing countries should continue the treatment and exclusively breastfeed their infants for 6 months.
Isentress 400mg Tablet may make you feel dizzy, sleepy, tired, or decrease alertness. If this happens, do not drive.

Caution is advised when driving or operating machinery.
Isentress 400mg Tablet is safe to use in patients with kidne
y disease. No dose adjustment of Isentress 400mg Tablet is recommended.
There is no data available. Please consult doctor before consuming the drug.

Patient Concerns

Frequently asked questions for Isentress 400mg Tablet

Frequently asked questions for Raltegravir

Q. Is raltegravir a protease inhibitor?
No. Raltegravir is an anti HIV drug. It does not have any known inhibitory effect on enzyme protease
Isentress is used for the treatment for human immunodeficiency virus (HIV) infection
How does Isentress inhibit HIV viral replication?Isentress works by inhibiting the action of an enzyme called integrase which is essential for the multiplication and survival of the virus (viral replication), thereby reducing HIV causing virus in the body.

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