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Invega Sustenna 75mg Injection

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Janssen Pharmaceuticals

Composition for Invega Sustenna 75mg Injection

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Primary uses of Invega Sustenna 75mg Injection

Potentiallyunsafewith
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Alcohol
MRP
10300
1 Injection in 1 vial
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Medicine Overview of Invega Sustenna Injection

uses

Uses of Invega Sustenna Injection

Invega Sustenna 75mg Injection is used in the treatment of schizophrenia and mania.
uses

Invega Sustenna Injection side effects

Common

Headache, Sleepiness, Insomnia (difficulty in sleeping), Parkinsonism, Akathisia, Dystonia.

uses

How to use Invega Sustenna Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Invega Sustenna Injection works

Invega Sustenna 75mg Injection is an atypical antipsychotic. It works by modulating the action of certain chemical messengers in the brain that affect thoughts.

In Depth Information on Invega Sustenna Injection

Expert advice for Invega Sustenna Injection

  • You can take paliperidone with or without breakfast, however, same pattern to be followed during the entire treatment.
  • Inform your doctor if you have known cardiovascular disease or family history of QT prolongation and if you are taking medicines that may prolong the QT interval.
  • Discontinue and inform you doctor immediately if you experience Neuroleptic Malignant Syndrome (NMS), characterised by hyperthermia (fever), muscle rigidity, autonomic instability, altered consciousness, and elevated serum creatine levels.
  • Inform your doctor if you have a swallowing, stomach or intestinal disorder that reduces your ability to swallow or pass foods by normal bowel movements.
  • You may suffer from tardive dyskinesia characterized by rhythmical, involuntary movements, predominantly of the tongue and/or face. Inform you doctor if you experience such symptoms.
  • You may suffer from priapism (prolonged and/or painful erection), inform your doctor if you experience such symptoms.
  • Do not drive or operate machinery as paliperidone may have some nervous effects and may cause visual disturbances. 
  • If you are a patient with diabetes, or with schizophrenia, taking paliperidone may increase the risk of developing diabetes. You should monitor glucose regularly while on paliperidone treatment.
  • Seek immediate medical attention if the thoughts of suicide occur when on paliperidone therapy.
  • Tell your doctor if you are or planning to become pregnant or are breastfeeding.
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Invega Sustenna Injection related warnings
Special precautions for Invega Sustenna Injection
Alcohol
CAUTION
Invega Sustenna 75mg Injection may cause excessive drowsiness and calmness with alcohol.
Pregnancy
WEIGH RISKS VS BENEFITS
Invega Sustenna 75mg Injection may be unsafe to use during pregnancy.
Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
Lactation
CAUTION
Invega Sustenna 75mg Injection is probably unsafe to use during lactation. Limited human data suggest that the drug could represent a significant risk to the baby.
Driving
Invega Sustenna 75mg Injection may make you feel dizzy, drowsy or affect your vision. Do not drive until your vision is clear.
Kidney
CAUTION
Invega Sustenna 75mg Injection should be used with caution in patients with kidney disease. Dose adjustment of Invega Sustenna 75mg Injection may be needed. Please consult your doctor.
Use of Invega Sustenna 75mg Injection is not recommended in patients with end-stage kidney disease.
Liver
Invega Sustenna 75mg Injection should be used with caution in patients with severe liver disease. Dose adjustment of Invega Sustenna 75mg Injection may be needed. Please consult your doctor.
Limited information is available on the use of Invega Sustenna 75mg Injection in these patients. No dose adjustment is recommended in patients with mild to moderate liver disease.

Patient Concerns

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Frequently asked questions about Invega Sustenna Injection

Frequently asked questions about Paliperidone

Q. Is paliperidone the same as risperidone?
Paliperidone gets converted to risperidone in the body and thus exerts similar actions
No, Invega sustenna is not a narcotic
Yes, Invega sustenna is an atypical antipsychotic
Invega sustenna is metabolized to its active metabolite risperidone by the CYP family of metabolizing enzymes
Yes, Invega sustenna is known to cause weight gain
Invega sustenna may cause priapism (prolonged and/or painful erection), which may contribute to erectile dysfunction. Please follow your doctor's advice regarding its use
Oral Invega sustenna may take 5 days to clear off from your body/system, whereas the injection may take around 4 to 8 months to clear off from your body/system.

Severely interacts with other drugs like

Taking Invega Sustenna with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Invega Sustenna with Voriconazole
LIFE-THREATENING
Medicines with composition Voriconazole: Vosicaz, Vorizol, Voraze, Rextro, Vhope, Vonaz, Vocozo, Voritek, Voritrop, Vorifit, Vorzu, Voritrol, Vfend, Vorizef, Vorier
Invega Sustenna with Ketoconazole
LIFE-THREATENING
Medicines with composition Ketoconazole: Hyporal, Hyphoral
Invega Sustenna with Clotrimazole
LIFE-THREATENING
Medicines with composition Clotrimazole: PV 6, Oraloz Mpt
Invega Sustenna with Itraconazole
LIFE-THREATENING
Invega Sustenna with Terbinafine
LIFE-THREATENING
Medicines with composition Terbinafine: Terbicutis, Tzorg, Tinazen, Zygter, Terfast, Fluty TF, Terbit, Tinafine
Invega Sustenna with Posaconazole
LIFE-THREATENING
Medicines with composition Posaconazole: Noxafil
Invega Sustenna with Oxyphenonium
SERIOUS
Medicines with composition Oxyphenonium: Antrenyl
Invega Sustenna with Fosphenytoin
SERIOUS
Medicines with composition Fosphenytoin: Fosphen, Fosentin
Invega Sustenna with Dapoxetine
SERIOUS
Medicines with composition Dapoxetine: Actinex, DA Sutra, Stay Tal, Dapoxy, Dapnex, Duraject, Appynite, Ristor, Dejac
Invega Sustenna with Nalbuphine
SERIOUS
Medicines with composition Nalbuphine: Rubuphine, Nalfy, Nacphin
Invega Sustenna with Paroxetine
SERIOUS
Medicines with composition Paroxetine: Parox, Pirotin, Paropex, Depaxil, Patriot, Xet, Parocen, Paroxee, Pxt, Praxet, Parot, Paxidep
Invega Sustenna with Diazepam
SERIOUS
Medicines with composition Diazepam: Peptica, Placidox, Shipam, Anxol, D P M, Paxum
Invega Sustenna with Lorazepam
SERIOUS
Invega Sustenna with Isopropamide
SERIOUS
Medicines with composition Isopropamide: Gastabid
Invega Sustenna with Pentazocine
SERIOUS
Medicines with composition Pentazocine: Fortwin
Invega Sustenna with Primidone
SERIOUS
Medicines with composition Primidone: Mysoline
Invega Sustenna with Spiramycin
SERIOUS
Medicines with composition Spiramycin: Spiramycin, Macromycin, Spiratox
Invega Sustenna with Chlordiazepoxide
SERIOUS
Medicines with composition Chlordiazepoxide: Zepox, Anxibrium, Poxid, Peaceoxide, Anxon H, Equilibrium, Cloxide, Librel
Invega Sustenna with Azithromycin
MINOR
Medicines with composition Azithromycin: Azitag, Maxithral, Azinova, Zithrocin, Azit, Zyloc, Nthrosin, Azilear, Rezim, Azrade, Bactiazi, Azistar, Elderaze, Azilup, Laz, Aziwis, Unizith, Rti, Azimore, Azee, Azivista, Azlo, Azivent, Azibest, Morzit, Zady, Aziklin, Azinol, Azitru, Remycine, Azileb, Azita, Aznee, Nazi, Azinix, Bio AZ, Azidep, Azirite, Zicin, Azibact, Zikem, Aziagio, Azad, Azithea, Threeomycin, A24, Azimacro, Aro, Aziclass, Uzazy, Azikaa, Azid, Zofacin, Trulimax, Azlupin, Uthral, Azigreat, Aziter, Azi Faith, Azigold, Rizax, Ecothral, Cazithro, Azitex, Azirox, Azitus XL, Azinkya, Izamed, Azicom, Azimed, Macrozin, Azipos, Azipeg, Aziforce, Azoo, Azipar, Azito, Azitab, Azicure, Rowezy, Azilac, Azax, Zithrokem, Azitrac, Azam, Azimount, Direkt, Servazith, Azimint, Azure, Azilin, Azest, Azinew, Azinext, Miomycin, Aziten, Aziway, Azitech, Azicox, Azindica, Aziber, Yash ZI, Zithro, Azisef, Azitin, Zarocin, Maazi, Zomycin, Azopil, Azipar O, Azithree, Azilide, Azigo, Karizma, Aziday, Zithrox, Azenas, Retramycin, Azcre, Pratham, Azoxyn, Vicon, Elzee, Azu OD, Zithcure, Xith, Azitop, Azibig, Azyric, Azifem, Azibiotic, Azifine, Aziline, Azilet, Azotis, Nanogram, Zitro, Zithium, Aziford, Azicid, Ertycin, Azeloc, Azimax, Myaz, Azirav, Zithree, Azycin, Azicrat, Ezecure, Azisoft, Qazi, Activa, Azisuper, Izabof, Zenmac, Aziwar, Azimon, Zohri, Azi Q, Azysafe, Azsuch, Azitras, Azirom, Azikem, Nuazy, Myazi, Zitromycin, Deftolide, Ronin, Nazith, Prazith, Azitsa, Azitas, Azumin, Azforin, Litazith, Flaag, Azmox, Zithromax, 3A, Azitive, Stfaz, Azilife, Azizen, Aziyug, Ortiza, AZ3, Zitis, Wiazi, Azomarc, Azimech, Azimist, Aziral, Aziset, Azro, Onazit, Gemycine, Stumz, Systhral, AN 500, Azauk, Zylid, Aziruth, Azinix Sdp, Azimark, Azire, Azith, Azovid, Maczed, Azitec, Zizom, Avitla
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