Paliperidone

Last updated 11 Jun 2025 | 01:47 PM (UTC)

Paliperidone Uses

Paliperidone is used in the treatment of mania and schizophrenia.

How Paliperidone works

Paliperidone is an atypical antipsychotic. It works by affecting the levels of chemical messengers (dopamine and serotonin) to improve mood, thoughts and behavior.

Common side effects of Paliperidone

Abnormal involuntary movements, Dizziness, Injection site reactions (pain, swelling, redness), Nystagmus (involuntary eye movement), Sleepiness, Tremors

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Medicine brands for Paliperidone

Invega Sustenna

Janssen Pharmaceuticals

₹0 to ₹5793

3 variant(s)

Palido

Torrent Pharmaceuticals Ltd

₹31 to ₹184

4 variant(s)

Palip

Intas Pharmaceuticals Ltd

₹34 to ₹147

4 variant(s)

Palicalm

Reliance Formulation Pvt Ltd

₹36 to ₹113

2 variant(s)

Pacenate

Shatayushi Healthcare Pvt Ltd

Oxford Pharmaceuticals Pvt Ltd

₹51 to ₹159

3 variant(s)

Palipex

Tripada Healthcare Pvt Ltd

₹81 to ₹81

1 variant(s)

Paliris LA

Sun Pharmaceutical Industries Ltd

₹2161 to ₹2985

3 variant(s)

Expert advice for Paliperidone

Take it in the morning, preferably at the same time every day.
To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
Use caution while driving or doing anything that requires concentration as Paliperidone can cause dizziness and sleepiness.
It may cause an increase in weight, blood sugar, cholesterol, and triglycerides (fat). Eat healthy, exercise, and monitor your levels regularly.
Monitor your blood sugar regularly as Paliperidone can affect blood sugar levels.
Do not stop taking Paliperidone without talking to your doctor first as it may cause a worsening of symptoms.

Frequently asked questions for Paliperidone

Q. Is paliperidone the same as risperidone?

Paliperidone gets converted to risperidone in the body and thus exerts similar actions

Q. Is Paliperidone a narcotic?

No, Paliperidone is not a narcotic

Q. Is Paliperidone an atypical antipsychotic?

Yes, Paliperidone is an atypical antipsychotic

Q. How is Paliperidone metabolized?

Paliperidone is metabolized to its active metabolite risperidone by the CYP family of metabolizing enzymes

Q. Does Paliperidone cause weight gain?

Yes, Paliperidone is known to cause weight gain

Q. Does Paliperidone cause erectile dysfunction?

Paliperidone may cause priapism (prolonged and/or painful erection), which may contribute to erectile dysfunction. Please follow your doctor's advice regarding its use

Q. How long does Paliperidone stay in your system?

Oral Paliperidone may take 5 days to clear off from your body/system, whereas the injection may take around 4 to 8 months to clear off from your body/system.