Glaniknase Injection

Streptokinase (NA)

Genuine

Authenticity Assured

Prescription

required

Cold stored

Stored between 2-8°C

Glaniknase Injection is a medicine used to break down harmful blood clots that have formed in the blood vessels. It is used to treat patients who have suffered a recent heart attack. It is also used in treating conditions such as pulmonary embolism and stroke.

Written By Dr. Swati Mishra, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 31 Mar 2026 | 02:31 PM (IST)

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General Information

Contains

Streptokinase (NA)

Marketer

Gland Pharma Limited

Storage

Store in a refrigerator (2 - 8°C). Do not freeze.

The content is shown in English

Product introduction

Glaniknase Injection is administered under the supervision of a doctor. Your doctor will decide the dose and duration of the medicine for you. The doctor may closely monitor your condition until you become stable.

Use of this medicine may cause injection site bleeding, nausea, allergic reaction, and a decrease in blood pressure. It may increase your risk of bleeding also. Your doctor will explain the benefits and risks associated with this medicine before it is administered. You should continue all your other medicines that are advised by the doctor for your long-term treatment even after this injection.

This medicine is used with caution for some people. Thus, you must inform the doctor if you are suffering from any bleeding disorder, kidney, or liver disease. Also, let your doctor know if you are pregnant or breastfeeding and about all the other medications that you are taking regularly.

Uses of Glaniknase Injection

Benefits of Glaniknase Injection

Heart attack
Glaniknase Injection helps dissolve the blood clots blocking the arteries of the heart during a heart attack. It restores blood flow quickly, reduces heart muscle damage, relieves chest pain, and lowers the risk of serious complications.

Pulmonary embolism
In pulmonary embolism, Glaniknase Injection works by breaking down the clots in the lungs’ blood vessels. This helps improve breathing, reduces chest discomfort, and prevents further strain on the heart.

Side effects of Glaniknase Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Glaniknase

Allergic reaction
Nausea
Injection site bleeding
Decrease in blood pressure

How to use Glaniknase Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Glaniknase Injection works

Glaniknase Injection works by dissolving the harmful blood clots in the blood vessels. This restores the blood flow to the affected tissue, thereby preventing tissue death and improving outcomes.

Quick tips

It increases your risk of bleeding. Be careful while shaving, cutting fingernails or toenails, using sharp objects or engaging in contact sports (e.g. football, wrestling).
Do not discontinue use without consulting your doctor as this may increase your chances of having another heart attack or stroke.
Glaniknase Injection helps break down blood clots in blood vessels, thereby treating conditions such as heart attack, pulmonary embolism, and stroke.
It should be given as soon as possible (within 12 hours) after the onset of a heart attack.
It is usually given by your nurse or doctor as an infusion (drip) into a vein.
It increases your risk of bleeding. Be careful while shaving, cutting fingernails or toenails, using sharp objects or engaging in contact sports (e.g. football, wrestling).
Do not discontinue use without consulting your doctor as this may increase your chances of having another heart attack or stroke.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Glaniknase Injection. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

The safety of Glaniknase Injection during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding

CONSULT YOUR DOCTOR

Information regarding the use of Glaniknase Injection during breastfeeding is not available. Please consult your doctor.

Driving

NOT RELEVANT

Not relevant, as Glaniknase Injection is intended for use in hospitalized patients.

Kidney

CAUTION

Glaniknase Injection should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
Use of Glaniknase Injection is not recommended in patients with severe kidney disease.

Liver

UNSAFE

Glaniknase Injection is unsafe to use in patients with liver disease and should be avoided.

Interaction with drugs

Taking Glaniknase with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Severe

Cilostazol (Oral Route)

Inform your doctor if you notice any signs of bleeding (bruising, bleeding gums, blood in stool/vomit/urine).

Severe

Urokinase (Injection Route)

Do not consume Streptokinase with Urokinase. If Streptokinase is essential, ensure a gap of At least 5 days between taking Streptokinase and Urokinase. Please consult your doctor. Urokinase may reduce the efficacy of Streptokinase.

Severe

Apixaban (Oral Route)

Do not consume Apixaban with Streptokinase. If concurrent use is essential, watch out for bleeding and consult your doctor immediately. Streptokinase may increase the effect of Apixaban.

Moderate

Ticagrelor (Oral Route)

Talk to your doctor if you notice any unusual symptoms.

Moderate

Aspirin (Oral Route)

Inform your doctor if you notice any signs of bleeding (bruising, bleeding gums, blood in stool/vomit/urine).

Frequently asked questions

Can the use of Glaniknase Injection increase the risk of bleeding?

Yes, Glaniknase Injection increases the risk of bleeding. Always be careful while doing activities that may cause an injury or bleeding. Tell your doctor immediately if you notice any abnormal bruising or bleeding.

What medicines should I avoid while taking Glaniknase Injection?

Glaniknase Injection can interact with several medicines. Do not take any medicine without talking to your doctor.

Fact Box

Chemical Class

Peptides

Habit Forming

Therapeutic Class

CARDIAC

Action Class

First-Generation Thrombolytics

Related lab tests

Platelet Count

References

Fox KA, White HD, Gersh BJ, et al. Antithrombotic Agents: Platelete Inhibitors, Acute Anticoagulants, Fibrinolytics, and Chronic Anticoagulants. In: Opie LH, Gersh BJ, editors. Drugs for the Heart. 8th ed. Philadelphia, Pennsylvania: Elsevier Saunders; 2013. pp. 384-85.
Weitz JI. Blood Coagulation and Anticoagulant, Fibrinolytic, and Antiplatelet Drugs. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 866.

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Gland Pharma Limited
Address: Gland Pharma Limited, 6-3-865/1/2, Greenland Apartments, Ameerpet, Hyderabad - 500016, India

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Glaniknase Injection

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General Information

Contains

Marketer

Storage

Product introduction

Uses of Glaniknase Injection

Benefits of Glaniknase Injection

Side effects of Glaniknase Injection

How to use Glaniknase Injection

How Glaniknase Injection works

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Cilostazol (Oral Route)

Urokinase (Injection Route)

Apixaban (Oral Route)

Ticagrelor (Oral Route)

Aspirin (Oral Route)

Frequently asked questions

Can the use of Glaniknase Injection increase the risk of bleeding?

What medicines should I avoid while taking Glaniknase Injection?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Platelet Count

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

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