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How it works

Apixaban prevents the formation of harmful blood clots.

Common side effects


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Expert advice

  • Talk to your doctor if you have bleeding disorders or uncontrolled high blood pressure.
  • Take precautions to avoid even minor injuries as apixaban can increase the risk of bleeding.
  • Your blood pressure (BP) should be monitored during and 24 hours after treatment.
  • Do not take apixaban if you have severe liver problems, kidney disease, or if you are on dialysis.
  • Inform your doctor if you have prosthetic heart valve or a catheter or an injection into your spinal column.
  • Do not stop taking apixaban unless advised, as stopping suddenly can increase the risk of blood clot or stroke.
  • Inform your doctor if you are consuming other blood-thinning medications such as aspirin, warfarin, and heparin.
  • Tell your doctor if you are pregnant or planning to become pregnant or are breastfeeding.

Frequently asked questions



Is apixaban an anticoagulant?
Yes, Apixaban is an anticoagulant that prevents formation and development of blood clot


Is apixaban safer than warfarin?
Apixaban is safer than warfarin as it affects only factor X, instead of all clotting factors affected by warfarin, leading to decreased risk of bleeding from various body organs. However, each of the drugs has its own uses and is used taking into consideration the requirements of the disease and the patient


Can I take ibuprofen with apixaban?
No. Using apixaban together with ibuprofen may increase the risk of bleeding, including severe and sometimes fatal haemorrhage

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Does apixaban affect International normalized ration (INR)?
Apixaban affects INR variably, however, INR levels which indicate coagulability of blood cannot be used to monitor apixaban treatment


How long does apixaban take to work?
Apixaban takes 1-2 hours to start acting, with peak effect seen at 3-4 hours of oral intake


Does apixaban have an antidote?
Apixaban does not have an antidote. Overdose may be corrected by surgical haemostasis or the transfusion of fresh frozen plasma


Is apixaban dialyzable?
No, apixaban is not dialyzable.

Content on this page was last updated on 15 March, 2017, by Dr. Varun Gupta (MD Pharmacology)