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Ticagrelor

INFORMATION

Uses

Ticagrelor is used in the treatment of heart attack.

How it works

Ticagrelor prevents platelets from sticking together which decreases the formation of harmful blood clots.

Common side effects

Allergic reaction, Shortness of breath, Chest pain, Vertigo, Dizziness, Altered heart rate

AVAILABLE MEDICINE

Expert advice

  • Do not use ticagrelor if you are allergic to it or any other component in the formulation.
  • Do not use ticagrelor if you are bleeding now or have bled recently inside your body, such as bleeding in your stomach or gut from an ulcer; if you have moderate to severe liver disease; stroke caused by bleeding in the brain.
  • Doctor’s advice should be considered in case of patients with following conditions: abnormally low heart rate; asthma or other lung problem or breathing difficulties; increased levels of uric acid.

Frequently asked questions

Ticagrelor

Q.Is ticagrelor an anticoagulant/beta blocker?
Ticagrelor is an anticoagulant (blood thinner) used to prevent clump formation in blood thereby reducing the propensity for heart attack and chest pain. It is not a beta blocker

Q.Is ticagrelor safe?
Ticagrelor is safe when taken at prescribed dose and duration as advised by your doctor

Q.Can I take Tylenol/ibuprofen with brilinta?
Brilinta (ticagrelor) can be taken with Tylenol (acetaminophen) but using brilinta together with ibuprofen may increase the risk of bleeding

Q.Why does ticagrelor cause dyspnea?
Reversible inhibition of P2Y12 (purinergic) receptor on sensory neurons by ticagrelor increases the sensation of dyspnea

Q.Is ticagrelor a prodrug?
No, it is not a prodrug

Q.Is ticagrelor better than clopidogrel?
Ticagrelor and clopidogrel are both blood thinning agents and have similar therapeutic effect. The response is different based on individual response

Q.Is ticagrelor FDA approved?
Yes, ticagrelor (a blood thinning agent) was approved by US FDA in July 2011 for reducing cardiovascular death and heart attack in patients with acute coronary syndromes

Q.Does ticagrelor lower blood pressure?
Ticagrelor can make blood pressure either low or high. These are side effects of this drug.


Content on this page was last updated on 24 November, 2016, by Dr. Varun Gupta (MD Pharmacology)