Geftibenz 250 Tablet

Gefitinib (250mg)

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Geftibenz 250 Tablet is used in the treatment of non-small cell lung cancer. It is used in patients in which it has spread to other parts of the body, who have abnormal epidermal growth factor receptor (EGFR) genes, and who have not had previous treatment for cancer.

Written By Dr. Subita Alagh, BDS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 14 Apr 2026 | 04:21 PM (IST)

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General Information

Contains

Gefitinib (250mg)

Marketer

Admac Pharma Ltd

Storage

Store below 25°C

The content is shown in English

Product introduction

Geftibenz 250 Tablet should be taken in a dose as recommended by the doctor. You should continue to take it as long as your doctor advises for it. The duration of treatment varies according to your need and response to treatment. Your doctor may advice for regular monitoring of liver function while your taking this medicine.

Common side effects include diarrhea, dry skin, loss of appetite, and nausea. Drink plenty of fluids to reduce the risk of side effects. Inform your doctor if any of the side effects bother you or get worse. In case you develop ulceration in mouth, changes in your vision, or breathing difficulties than it is better to inform the doctor.

Women who are undergoing treatment should use effective contraception method. It is important to avoid pregnancy during the treatment and for a month after completing the course of medicine. Let your doctor also know about all the other medications you are taking.

Uses of Geftibenz Tablet

Non-small cell lung cancer

Benefits of Geftibenz Tablet

Non-small cell lung cancer
Non-small cell lung cancer is one of the major kinds of lung cancer and it affects both smokers as well as non-smokers. Geftibenz 250 Tablet helps treat non-small cell lung cancer and may be given alone or in combination with other medicines. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.

Side effects of Geftibenz Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Geftibenz

Diarrhea
Dry skin
Loss of appetite
Nausea
Rash
Vomiting
Weakness
Allergic reaction

How to use Geftibenz Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Geftibenz 250 Tablet may be taken with or without food.

How Geftibenz Tablet works

Geftibenz 250 Tablet is an anti-cancer medication. It works by blocking the action of the abnormal protein that signals cancer cells to multiply. This helps to stop or slow the spread of cancer cells.

All substitutes for Geftibenz 250 Tablet

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

Geftibenz 250 Tablet helps treat non-small cell lung cancer that is locally advanced, or has spread to other areas of the body.
Take it with or without food, preferably at the same time each day.
Do not take antacids (to reduce the acid level of your stomach) 2 hours before or 1 hour after taking this medicine.
Diarrhea may occur as a side effect. Drink plenty of fluids and inform your doctor if it doesn't stop or if you find blood in your stools.
Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine and for a month after you stop taking it.
Inform your doctor if you develop ulceration in your mouth, changes in your vision or if you experience a worsening cough, shortness of breath, or breathing difficulties while taking this medicine.
Your doctor may want you to have regular blood tests to monitor your liver function while you are having treatment with this medicine.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Geftibenz 250 Tablet. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Geftibenz 250 Tablet is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding

CAUTION

Geftibenz 250 Tablet should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from the body.

Driving

SAFE

Geftibenz 250 Tablet does not usually affect your ability to drive.

Kidney

CAUTION

Geftibenz 250 Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.

Liver

CAUTION

Geftibenz 250 Tablet should be used with caution in patients with severe liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Geftibenz with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Life-threatening

Vinorelbine (Injection Route)

Do not consume Gefitinib with Vinorelbine.

Severe

Vinblastine (Injection Route)

Concomitant use is not recommended. Please consult with your doctor. Gefitinib may raise blood levels of Vinblastine.

Severe

Vincristine (Injection Route)

Concomitant use is not recommended. Please consult with your doctor. Gefitinib may raise blood levels of Vincristine.

Moderate

Paroxetine (Oral Route)

Watch out for symptoms of Gefitinib side effects such as diarrhea, dry eye, vomiting, breathing problems, decreased appetite or rash and consult your doctor if you experience them. Paroxetine may raise blood levels of Gefitinib.

Moderate

Aprepitant (Oral Route)

Watch out for symptoms of Aprepitant side effects such as diarrhea, dry eye, vomiting, breathing problems, decreased appetite or rash and consult your doctor if you experience them. Aprepitant may raise blood levels of Gefitinib.

Frequently asked questions

What is Geftibenz 250 Tablet used for?

Geftibenz 250 Tablet is a prescription medicine used to treat a type of lung cancer called non-small cell lung cancer (NSCLC) that has specific changes in the EGFR gene. It is typically used in people whose cancer has spread and who haven’t received chemotherapy yet.

Who can take Geftibenz 250 Tablet?

Geftibenz 250 Tablet is recommended for adults with advanced NSCLC that tests positive for certain EGFR mutations. Your doctor will perform a special test before starting Geftibenz 250 Tablet treatment to confirm if this medicine is suitable for you.

What are the serious side effects of Geftibenz 250 Tablet?

Geftibenz 250 Tablet may rarely cause serious side effects, including lung inflammation (interstitial lung disease), liver damage, severe diarrhea, or eye problems. Seek medical help immediately if you experience breathing difficulty, eye pain, yellowing of the skin or eyes, or dark urine.

What precautions should I follow while on Geftibenz 250 Tablet treatment?

While taking Geftibenz 250 Tablet, you should get regular liver function tests and chest scans, avoid prolonged sun exposure due to skin sensitivity, and report any vision changes or breathing difficulties right away.

How long will I need to take Geftibenz 250 Tablet?

You should take Geftibenz 250 Tablet for as long as your doctor recommends. Treatment may continue until your cancer progresses or side effects become unmanageable. Regular follow-up tests advised by your doctor will help guide this decision.

Fact Box

Chemical Class

Quinazolinamines

Habit Forming

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Tyrosine Kinase Inhibitors (TKIs)

References

Chabner BA, Barnes J, Neal J, et al. Targeted Therapies: Tyrosine Kinase Inhibitors, Monoclonal Antibodies, and Cytokines. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1734-35.
Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 954-55.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 616-17.
Gefitinib. Luton, Bedfordshire: AstraZeneca UK Limited; 2009 [revised 23 Apr. 2018]. [Accessed 232 Jan. 2019] (online) Available from:
Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Gefitinib. [Updated 2018 Dec 3]. [Accessed 18 Feb. 2020] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:
CiplaMed. Gefitinib [Prescribing Information]. [Accessed 06 Apr. 2024] (online) Available from:
Gefitinib. Cheshire, United Kingdom: AstraZeneca UK Ltd.; [Accessed 11 Feb. 2026] (online). Available from:
Gefitinib. Weston, Florida: Apotex Corp.; 2024 [Accessed 11 Feb. 2026] (online). Available from:

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Admac Pharma Ltd
Address: SCO 84, Sector 5, Panchkula (Haryana), 134112 INDIA.

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Geftibenz 250 Tablet

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Geftibenz Tablet

Benefits of Geftibenz Tablet

Side effects of Geftibenz Tablet

How to use Geftibenz Tablet

How Geftibenz Tablet works

All substitutes for Geftibenz 250 Tablet

Gefitero Tablet

Geftib Tablet

Gefticip Tablet

Geftistar 250mg Tablet

Gefticip Tablet

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Vinorelbine (Injection Route)

Vinblastine (Injection Route)

Vincristine (Injection Route)

Paroxetine (Oral Route)

Aprepitant (Oral Route)

Frequently asked questions

What is Geftibenz 250 Tablet used for?

Who can take Geftibenz 250 Tablet?

What are the serious side effects of Geftibenz 250 Tablet?

What precautions should I follow while on Geftibenz 250 Tablet treatment?

How long will I need to take Geftibenz 250 Tablet?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

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