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Aprepitant

INFORMATION

Uses

Aprepitant is used in vomiting.

How it works

Aprepitant inhibits the action of a chemical in the brain that may cause vomiting during the treatment with cancer drugs.

Common side effects

Stomach pain, Nausea, Constipation, Diarrhoea, Dizziness, Flatulence, Hair loss, Headache, Heartburn, Hiccup, Loss of appetite, Skin rash, Itching, Urticaria, Fatigue, Weakness, Fever

AVAILABLE MEDICINE

Expert advice

  • Aprepitant can only prevent nausea and vomiting and is not used for its treatment. Do not start aprepitant if you are already having nausea or vomiting.
  • If you have liver disease, you may be monitored with liver function test regularly, as it may affect the breakdown of this medicine in your body.
  • You are advised to use another or additional non-hormonal form of birth control method during and after up to 2 months of using aprepitant, as certain hormonal birth control [e.g. birth control pills, skin patches, implants, and certain intrauterine devices (IUDs)] may not work adequately when taken along with aprepitant. 
  • Do not drive or use machinery while taking Aprepitant as it may make you feel dizzy and sleepy.

Frequently asked questions

Aprepitant

Q.What are aprepitant capsules/ what is aprepitant used for?
Aprepitant is used in adults in combination with other medicines to prevent nausea and vomiting caused by chemotherapy (cancer treatment) or in some cases after a surgery

Q.How does aprepitant work?
Aprepitant is an antiemetic that works by blocking the action of neurokinin, a natural substance in the brain that causes nausea and vomiting.


Content on this page was last updated on 25 November, 2016, by Dr. Varun Gupta (MD Pharmacology)