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Aprepitant

Written By Dr. Sakshi JainReviewed By Dr. Rajeev Sharma
Last updated 25 Nov 2025 | 09:34 AM (UTC)

Aprepitant Uses

Aprepitant is used to prevent nausea and vomiting due to chemotherapy.

How Aprepitant works

Aprepitant is an antiemetic medication. It works by blocking the action of a chemical messenger (neurokinin) in the brain that may cause nausea and vomiting during anti-cancer treatment (chemotherapy).

Common side effects of Aprepitant

Hiccup, Fatigue, Weakness, Dehydration, Abdominal pain, Decreased white blood cell count, Diarrhea, Dyspepsia, Increased alanine aminotransferase
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Expert advice for Aprepitant

  • Aprepitant helps prevent nausea and vomiting caused by certain chemotherapy medicines.
  • It will not help if you already have nausea and vomiting.
  • Do not use it continuously for a long time.
  • It is recommended to take Aprepitant 1 hour before chemotherapy treatment (Day 1) and in the morning on Days 2 and 3.
  • It may damage sperms and may harm the baby if used during pregnancy or breastfeeding.

Frequently asked questions for Aprepitant

Aprepitant is used in adults in combination with other medicines to prevent nausea and vomiting caused by chemotherapy (cancer treatment) or in some cases after a surgery
Aprepitant is an antiemetic that works by blocking the action of neurokinin, a natural substance in the brain that causes nausea and vomiting.