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Aprepitant is used in vomiting

How it works

Aprepitant inhibits the action of a chemical in the brain that may cause vomiting during the treatment with cancer drugs.

Common side effects

Headache, Decreased appetite, Dyspepsia, Fatigue, Liver enzyme abnormal, Constipation

Available Medicine

Expert advice

  • Aprepitant can only prevent nausea and vomiting and is not used for its treatment. Do not start aprepitant if you are already having nausea or vomiting.
  • If you have liver disease, you may be monitored with liver function test regularly, as it may affect the breakdown of this medicine in your body.
  • You are advised to use another or additional non-hormonal form of birth control method during and after up to 2 months of using aprepitant, as certain hormonal birth control [e.g. birth control pills, skin patches, implants, and certain intrauterine devices (IUDs)] may not work adequately when taken along with aprepitant. 
  • Do not drive or use machinery while taking Aprepitant as it may make you feel dizzy and sleepy.

Frequently asked questions


Q. What are aprepitant capsules/ what is aprepitant used for?
Aprepitant is used in adults in combination with other medicines to prevent nausea and vomiting caused by chemotherapy (cancer treatment) or in some cases after a surgery

Q. How does aprepitant work?
Aprepitant is an antiemetic that works by blocking the action of neurokinin, a natural substance in the brain that causes nausea and vomiting.

Content on this page was last updated on 19 January, 2017, by Dr. Varun Gupta (MD Pharmacology)