Frepram 40mg Tablet

Reviewed By Dr. Rajeev Sharma, MBA, MBBS

Last updated on 25 Nov 2025 | 03:05 PM (IST)

Frepram 40mg Tablet is a type of antidepressant belonging to the selective serotonin reuptake inhibitor (SSRI) group of medicines. It is prescribed to treat depression, where it helps to make you feel better and prevent new episodes of depression. This medicine is also used to treat panic disorder.

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General Information

Contains

Citalopram (40mg)

Marketer

Sunrise Remedies Pvt Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Frepram 40mg Tablet can be taken with or without food. The dose and how often you need it will be decided by your doctor so that you get the right amount to control your symptoms. Your doctor may start you on a lower dose and increase it gradually. Do not change the dose or stop taking it without talking to your doctor, even if you feel well. Doing so may make your condition worse or you may suffer from unpleasant withdrawal symptoms (anxiety, restlessness, palpitations, dizziness, sleep disturbances, etc).

To get the most benefit, take this medicine regularly at the same time each day. Your doctor may advise you to take it in the morning if you have trouble sleeping. It may take a few weeks before you start feeling better. Let your doctor know if you do not see any improvement even after 4 weeks.

Some common side effects of this medicine include nausea, vomiting, fatigue, dry mouth, increased sweating, insomnia (difficulty in sleeping), decreased sexual drive, delayed ejaculation, and erectile dysfunction. Some people may experience sleepiness after taking this medicine. Let your doctor know straight away if you develop any sudden worsening of mood or any thoughts about harming yourself.

Before taking Frepram 40mg Tablet, you should tell your doctor if you have epilepsy (seizure disorder or fits), diabetes, liver or kidney disease, any heart problems, or are currently taking medicines for depression known as MAO inhibitors. These may affect your treatment. Please tell your doctor about all the medicines you are taking to make sure you are safe.

Uses of Frepram Tablet

Benefits of Frepram Tablet

Panic disorder
Frepram 40mg Tablet can help relieve symptoms of many panic disorders including panic attacks. It can help you feel calmer and improve your ability to deal with problems. Do not stop taking it, even when you feel better, unless your doctor advises you to.

Side effects of Frepram Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Frepram

Nausea
Vomiting
Increased sweating
Insomnia (difficulty in sleeping)
Low sexual desire
Erectile dysfunction
Dizziness
Fatigue
Delayed ejaculation

How to use Frepram Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Frepram 40mg Tablet may be taken with or without food.

How Frepram Tablet works

Frepram 40mg Tablet is one of a group of antidepressants called selective serotonin reuptake inhibitors, or SSRIs. It is thought to be work by enhancing the level of mood-enhancing neurotransmitters called serotonin in the brain. This may help you to improve your energy level and feelings of well-being.

All substitutes for Frepram 40mg Tablet

For information purposes only. Consult a doctor before taking any medicine.

Cytop 40mg Tablet

by Wockhardt Ltd

₹5.25/tablet

20% cheaper

Quick tips

It can take up to 8 to 12 weeks to see the medicine full effects on your mood.
Take it with food to avoid stomach upset.
It causes less drowsiness as compared to other antidepressant medications.
Don't drive or do anything requiring concentration until you know how Frepram 40mg Tablet affects you.
Talk to your doctor if you notice sudden mood changes or develop suicidal thoughts.
Inform your doctor if you experience decreased sex drive or difficulty having an orgasm.
Do not stop taking the medication suddenly without talking to your doctor.
It can take 2-3 weeks for Frepram 40mg Tablet to start working.
Do not stop treatment suddenly as this may cause upset stomach, flu-like withdrawal symptoms and sleep disturbance.
If your doctor asks you to stop Frepram 40mg Tablet, you should reduce the dose slowly over 4 weeks.
Avoid consuming alcohol when taking Frepram 40mg Tablet, as it may cause excessive drowsiness and calmness.
The addiction/dependence potential of Frepram 40mg Tablet is very less.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Frepram 40mg Tablet

Pregnancy

CONSULT YOUR DOCTOR

The safety of Frepram 40mg Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding

CONSULT YOUR DOCTOR

Frepram 40mg Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.
Babies should be monitored for behavioral side effects such as sleepiness or fussiness.

Driving

UNSAFE

Frepram 40mg Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Frepram 40mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
Limited information is available on the use of Frepram 40mg Tablet in these patients. No dose adjustment is recommended in patients with mild to moderate kidney disease.

Liver

CAUTION

Frepram 40mg Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Frepram with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Life-threatening

Thioridazine (Oral Route)

Do not consume Thioridazine with Citalopram.

Life-threatening

Amiodarone (Oral Route)

Do not consume Amiodarone with Citalopram.

Life-threatening

Moclobemide (Oral Route)

Do not consume Moclobemide with Citalopram. If Moclobemide is essential, ensure a gap of at least 1 week after discontinuing Citalopram. Please consult your doctor.

Life-threatening

Aripiprazole (Oral Route)

Do not consume Aripiprazole with Citalopram.

Life-threatening

Pimozide (Oral Route)

Do not consume Pimozide with Citalopram.

Frequently asked questions

What is Frepram 40mg Tablet used for? How does it work?

Frepram 40mg Tablet belongs to a class of medicines known as selective serotonin reuptake inhibitors (SSRIs). Frepram 40mg Tablet is used to treat depression and panic disorder. It helps to improve your energy levels and elevates your mood. This medication works by restoring the balance of a chemical substance (serotonin) in the brain which helps to relieve depression and symptoms of panic disorder such as excessive fear, sweating, rapid heart rate, trembling or shaking, shortness of breath, chills etc.

Does Frepram 40mg Tablet make you gain weight?

Weight changes may be seen while using Frepram 40mg Tablet, so monitor your weight closely. Frepram 40mg Tablet belongs to a class of medicines known as selective serotonin reuptake inhibitors (SSRIs). Although SSRIs are associated with weight loss at first, long-term use of SSRIs may cause an increase in the weight. Long-term use is considered when the treatment lasts longer than six months. If these weight changes bother you, please consult your doctor.

Can you drink alcohol while taking Frepram 40mg Tablet?

No, it is advised not to take alcohol while taking Frepram 40mg Tablet. Frepram 40mg Tablet can cause sleepiness or may affect your ability to make decisions, think clearly, or react quickly. And taking alcohol with this medicine will only worsen these side effects. Therefore, you must avoid alcohol if you are on Frepram 40mg Tablet.

Can Frepram 40mg Tablet cause abnormal heartbeat or arrhythmia?

Yes, Frepram 40mg Tablet has been found to cause prolongation of the QT interval (a type of ECG abnormality) that can lead to arrhythmia (abnormal heartbeat or heart rhythm), which can be dangerous. However, this is very rare according to scientific research reports. Moreover, abnormalities in electrolyte levels (such as potassium and magnesium) may also increase the risk of abnormalities in the heartbeat of people suffering from heart problems. Such people must have an ECG review, before as well as during treatment with Frepram 40mg Tablet. However, the final decision will be only made by your doctor, after analyzing your health condition and considering all possible risks and benefits of this medicine.

What are the side effects of Frepram 40mg Tablet?

The most common side effects of Frepram 40mg Tablet are low sexual desire, vomiting, insomnia (difficulty in sleeping), orthostatic hypotension (sudden lowering of blood pressure on standing), anorgasmia (decreased orgasm), nausea, weight gain, erectile dysfunction, stomach upset, and restlessness. Please consult your doctor if these do not resolve or worry you. Your doctor will suggest ways to prevent or treat these side effects.

Is it better to take Frepram 40mg Tablet in the morning or at night?

It is usually recommended to take Frepram 40mg Tablet once a day in the morning since it can keep you awake if taken late at night. You can take it with or without food. You should prefer taking it at the same time each day so that you remember to take it.

Fact Box

Chemical Class

Phenylbutylamines

Habit Forming

Therapeutic Class

NEURO CNS

Action Class

Selective Seretonin Reuptake Inhibitors (SSRIs)

References

Stahl SM, editor. Citalopram. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 123-28.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 281-85.
Citalopram hydrobromide. St Albans, UK: Lundbeck Limited; 1995 [revised Dec. 2016]. [Accessed 23 Jan. 2019] (online) Available from:
Citalopram. St. Louis: Forest Pharmaceuticals; [revised 2013]. [Accessed 22 Mar. 2019] (online) Available from:
Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 20 Mar. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 20 Mar. 2019] (online) Available from:

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Sunrise Remedies Pvt Ltd
Address: 104, Sahajanand Complex, Nr. Thaltej Cross Roads, Off S. G. High Way, Thaltej, AHEMDABAD - 380054, GUJARAT - INDIA

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Provide right medicines

Prescriptions are complex documents. We proof read and recheck at various steps to provide you the right medication in the correct form and dose

In accordance with the law

Most medicines cannot be sold without a valid prescription, as per the Drugs and Cosmetics Act, 1940 and Rules, 1945

Frepram 40mg Tablet

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General Information

Contains

Marketer

Storage

Product introduction

Uses of Frepram Tablet

Benefits of Frepram Tablet

Side effects of Frepram Tablet

How to use Frepram Tablet

How Frepram Tablet works

All substitutes for Frepram 40mg Tablet

Cytop 40mg Tablet

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Thioridazine (Oral Route)

Amiodarone (Oral Route)

Moclobemide (Oral Route)

Aripiprazole (Oral Route)

Pimozide (Oral Route)

Frequently asked questions

What is Frepram 40mg Tablet used for? How does it work?

Does Frepram 40mg Tablet make you gain weight?

Can you drink alcohol while taking Frepram 40mg Tablet?

Can Frepram 40mg Tablet cause abnormal heartbeat or arrhythmia?

What are the side effects of Frepram 40mg Tablet?

Is it better to take Frepram 40mg Tablet in the morning or at night?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

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