Fosamac 150 Injection

Fosaprepitant (150mg)

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required

Cold stored

Stored between 2-8°C

Fosamac 150 Injection is a prescription medicine used to prevent nausea and vomiting caused by chemotherapy.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 25 Nov 2025 | 03:05 PM (IST)

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Fosamac 150 Injection

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Aprecap 150mg Injection

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Fosaprepitant (150mg)

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General Information

Contains

Fosaprepitant (150mg)

Marketer

Admac Pharma Ltd

Storage

Store in a refrigerator (2 - 8°C). Do not freeze.

The content is shown in English

Product introduction

Fosamac 150 Injection is given under the supervision of healthcare professional. Moreover, it is better to take it at a fixed time and you should not stop taking this medication suddenly without talking to your doctor. In case you have missed a dose than it is better to take it as soon as you remember it and finish the full course of treatment even if you feel better. Your doctor may advice for regular monitoring of liver function test while taking this medicine.

It has side effects like fatigue, headache, loss of appetite, constipation and hiccups. Dizziness and sleepiness may also occur as a side effect, so do not drive or do anything that requires mental focus until you know how this medicine affects you.

Uses of Fosamac Injection

Nausea and vomiting due to chemotherapy

Benefits of Fosamac Injection

Nausea and vomiting due to chemotherapy
Chemotherapy-induced nausea and vomiting a distressing side effects experienced by cancer patients undergoing treatment. It can lead to dehydration, poor nutrition, and reduced quality of life, often interfering with the continuation of therapy. Fosamac 150 Injection helps prevent these symptoms by blocking neurokinin and effectively reducing both the immediate and delayed phases of nausea and vomiting. It improves patient comfort, supports better adherence to chemotherapy, and enhances overall treatment outcomes.

Side effects of Fosamac Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Fosamac

Headache
Hiccup
Indigestion
Fatigue
Decreased appetite
Constipation

How to use Fosamac Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Fosamac Injection works

Fosamac 150 Injection is an antiemetic medication. It works by blocking the action of a chemical messenger (neurokinin) in the brain that may cause nausea and vomiting during anti-cancer treatment (chemotherapy).

All substitutes for Fosamac 150 Injection

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

Fosamac 150 Injection is given as a drip into the vein under the supervision of a doctor.
It makes you feel dizzy or drowsy. Do not drive until you know how this medicine affects you.
You will be monitored for liver functioning regularly while taking this medication.
Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Fosamac 150 Injection

Pregnancy

SAFE IF PRESCRIBED

Fosamac 150 Injection is generally considered safe to use during pregnancy. Animal studies do not indicate harmful effects. However, there are limited human studies.

Breast feeding

CONSULT YOUR DOCTOR

Fosamac 150 Injection may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.

Driving

UNSAFE

Fosamac 150 Injection may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

SAFE IF PRESCRIBED

Fosamac 150 Injection is safe to use in patients with kidney disease. No dose adjustment is recommended.

Liver

CAUTION

Fosamac 150 Injection should be used with caution in patients with severe liver disease. Dose adjustment may be needed.
No dose adjustment is recommended in patients with moderate to severe liver disease.

Interaction with drugs

Taking Fosamac with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Severe

Apalutamide (Oral Route)

Concomitant use should be avoided. Please consult with your doctor. Apalutamide may increase the metabolism of Fosaprepitant.

Moderate

Gliclazide (Oral Route)

Monitor your blood sugar levels regularly. Fosaprepitant may reduce blood levels of Gliclazide.

Moderate

Diltiazem (Oral Route)

If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations.

Moderate

Trabectedin (Injection Route)

If concurrent use is essential, watch out for symptoms such as nausea, vomiting, impaired movements, rash, diarrhea, dizziness, or drowsiness, and consult your doctor if you experience them. Fosaprepitant may raise blood levels of Trabectedin.

Moderate

Allylestrenol (Oral Route)

It is recommended to use barrier methods (like condoms), IUDs, or a depot for contraception. Your doctor may monitor your treatment closely and adjust the doses as per the observations. Use barrier methods (like condoms) for contraception to reduce the risk of HIV infection. Fosaprepitant may reduce blood levels of Allylestrenol.

Fact Box

Chemical Class

Phenylmorpholines

Habit Forming

Therapeutic Class

GASTRO INTESTINAL

Action Class

Neurokinin-1 (NK1) Receptor Antagonists

References

McQuaid KR. Drugs Used in the Treatment of Gastrointestinal Diseases. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 1086.
Fosaprepitant dimeglumine. Hoddesdon, Hertfordshire: Merck Sharp & Dohme Limited; 2008 [revised 29 Nov. 2018]. [Accessed 29 Jan. 2019] (online) Availale from:
Fosaprepitant. Highway, Greenville, NC: DSM Pharmaceuticals; 2008. [Accessed 28 Mar. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 28 Mar. 2019] (online) Available from:

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Admac Pharma Ltd
Address: SCO 84, Sector 5, Panchkula (Haryana), 134112 INDIA.

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Fosamac 150 Injection

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Fosamac Injection

Benefits of Fosamac Injection

Side effects of Fosamac Injection

How to use Fosamac Injection

How Fosamac Injection works

All substitutes for Fosamac 150 Injection

Fosaport 150mg Injection

Aprecap 150mg Injection

Fosa Injection

Apritant 150mg Injection

Apregen 150mg Injection

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Apalutamide (Oral Route)

Gliclazide (Oral Route)

Diltiazem (Oral Route)

Trabectedin (Injection Route)

Allylestrenol (Oral Route)

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

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