Fosamac 150 Injection

Fosaprepitant (150mg)

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Cold stored

Stored between 2-8°C

Fosamac 150 Injection is a prescription medicine used to prevent nausea and vomiting caused by chemotherapy.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 15 Sep 2026 | 01:03 AM (IST)

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General Information

Contains

Fosaprepitant (150mg)

Marketer

Admac Pharma Ltd

Storage

Store in a refrigerator (2 - 8°C). Do not freeze.

The content is shown in English

Product introduction

Fosamac 150 Injection is given under the supervision of healthcare professional. Moreover, it is better to take it at a fixed time and you should not stop taking this medication suddenly without talking to your doctor. In case you have missed a dose than it is better to take it as soon as you remember it and finish the full course of treatment even if you feel better. Your doctor may advice for regular monitoring of liver function test while taking this medicine.

It has side effects like fatigue, headache, loss of appetite, constipation and hiccups. Dizziness and sleepiness may also occur as a side effect, so do not drive or do anything that requires mental focus until you know how this medicine affects you.

Uses of Fosamac Injection

Nausea and vomiting due to chemotherapy

Benefits of Fosamac Injection

Nausea and vomiting due to chemotherapy
Chemotherapy-induced nausea and vomiting a distressing side effects experienced by cancer patients undergoing treatment. It can lead to dehydration, poor nutrition, and reduced quality of life, often interfering with the continuation of therapy. Fosamac 150 Injection helps prevent these symptoms by blocking neurokinin and effectively reducing both the immediate and delayed phases of nausea and vomiting. It improves patient comfort, supports better adherence to chemotherapy, and enhances overall treatment outcomes.

Side effects of Fosamac Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Fosamac

Indigestion
Fatigue
Weakness
Diarrhea
Decreased white blood cell count (neutrophils)
Anemia (low number of red blood cells)
Peripheral neuropathy (tingling and numbness of feet and hand)
Decreased white blood cell count (lymphocytes)
Urinary tract infection
Pain in extremity

How to use Fosamac Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Fosamac Injection works

Fosamac 150 Injection is an antiemetic medication. It works by blocking the action of a chemical messenger (neurokinin) in the brain that may cause nausea and vomiting during anti-cancer treatment (chemotherapy).

All substitutes for Fosamac 150 Injection

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

Fosamac 150 Injection is given as a drip into the vein under the supervision of a doctor.
It makes you feel dizzy or drowsy. Do not drive until you know how this medicine affects you.
You will be monitored for liver functioning regularly while taking this medication.
Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Fosamac 150 Injection. Please consult your doctor.

Pregnancy

SAFE IF PRESCRIBED

Fosamac 150 Injection is generally considered safe to use during pregnancy. Animal studies do not indicate harmful effects. However, there are limited human studies.

Breast feeding

CONSULT YOUR DOCTOR

Information regarding the use of Fosamac 150 Injection during breastfeeding is not available. Please consult your doctor.

Driving

UNSAFE

Fosamac 150 Injection may cause side effects that could affect your ability to drive.

Kidney

CAUTION

Fosamac 150 Injection should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.

Liver

CONSULT YOUR DOCTOR

There is limited data available on the use of Fosamac 150 Injection in patients with liver disease.
No dose adjustment is recommended in patients with moderate to severe liver disease.

Interaction with drugs

Taking Fosamac with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Severe

Apalutamide (Oral Route)

Concomitant use should be avoided. Please consult with your doctor. Apalutamide may increase the metabolism of Fosaprepitant.

Moderate

Gliclazide (Oral Route)

Monitor your blood sugar levels regularly. Fosaprepitant may reduce blood levels of Gliclazide.

Moderate

Diltiazem (Oral Route)

If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations.

Moderate

Trabectedin (Injection Route)

If concurrent use is essential, watch out for symptoms such as nausea, vomiting, impaired movements, rash, diarrhea, dizziness, or drowsiness, and consult your doctor if you experience them. Fosaprepitant may raise blood levels of Trabectedin.

Moderate

Allylestrenol (Oral Route)

It is recommended to use barrier methods (like condoms), IUDs, or a depot for contraception. Your doctor may monitor your treatment closely and adjust the doses as per the observations. Use barrier methods (like condoms) for contraception to reduce the risk of HIV infection. Fosaprepitant may reduce blood levels of Allylestrenol.

Frequently asked questions

What is Fosamac 150 Injection used for?

Fosamac 150 Injection is used to help prevent nausea and vomiting that may be caused by cancer chemotherapy. These symptoms can occur during treatment or even several days after treatment and can affect nutrition, hydration, and overall comfort. Fosamac 150 Injection can help prevent chemotherapy-induced nausea and vomiting, making cancer treatment more manageable and improving quality of life during therapy.

How does Fosamac 150 Injection work?

Fosamac 150 Injection contains Fosaprepitant, a medicine used to prevent nausea and vomiting. It works by blocking the effect of a natural substance in the brain called substance P. Substance P is involved in triggering nausea and vomiting. Fosaprepitant blocks these signals to help prevent both the immediate nausea that can occur shortly after chemotherapy and the delayed nausea that can occur over the following days.

Can Fosamac 150 Injection prevent delayed vomiting after chemotherapy?

Yes. Fosamac 150 Injection is specifically used to help prevent both acute and delayed nausea and vomiting caused by chemotherapy. Symptoms may develop several days after treatment and can be difficult to control. The prolonged action of Fosamac 150 Injection helps reduce the likelihood of these symptoms occurring after chemotherapy.

Can Fosamac 150 Injection be used for motion sickness or routine nausea?

No. Fosamac 150 Injection is primarily used to prevent nausea and vomiting related to chemotherapy. It is not generally used for motion sickness, routine stomach upset, or other common causes of nausea unless specifically recommended by your doctor for a particular medical reason.

When is Fosamac 150 Injection usually given before chemotherapy?

Fosamac 150 Injection is usually administered by a doctor as part of an anti-nausea treatment plan before chemotherapy begins. The timing depends on the specific chemotherapy regimen and your doctor's recommendations. It is generally given before treatment starts to help prevent symptoms from developing.

Can I administer Fosamac 150 Injection myself at home?

No. Fosamac 150 Injection is an injection that should only be administered by a doctor in a hospital, clinic, or healthcare setting. Self-administration is not recommended because proper preparation, dosing, and monitoring are important for safe and effective treatment.

Can Fosamac 150 Injection interact with diabetes medicines such as Glimepiride or Gliclazide?

Yes. Some medicines, including certain diabetes medicines such as Glimepiride and Gliclazide, may interact with Fosamac 150 Injection. Inform your doctor about all medicines you are taking before treatment. Your doctor may monitor you more closely or make treatment adjustments if necessary.

Does Fosamac 150 Injection interact with heart medicines such as Diltiazem?

Yes. Fosamac 150 Injection may interact with certain heart medicines, including Diltiazem. Before receiving treatment, tell your doctor about all prescription medicines, over-the-counter products, and supplements you use. This helps identify and manage any potential interactions appropriately.

What are the signs of a serious allergic reaction to Fosamac 150 Injection?

Seek immediate medical attention if you develop difficulty breathing, wheezing, swelling of the face, lips, tongue, or throat, severe itching, a widespread rash, or sudden dizziness after receiving Fosamac 150 Injection. These symptoms may indicate a serious allergic reaction that requires urgent treatment.

How long does the effect of Fosamac 150 Injection last?

Fosamac 150 Injection is designed to provide protection against chemotherapy-related nausea and vomiting beyond the day of treatment. Its effects can help cover both the immediate period after chemotherapy and the delayed phase when nausea and vomiting may still occur, providing extended symptom prevention.

Fact Box

Chemical Class

Phenylmorpholines

Habit Forming

Therapeutic Class

GASTRO INTESTINAL

Action Class

Neurokinin-1 (NK1) Receptor Antagonists

References

McQuaid KR. Drugs Used in the Treatment of Gastrointestinal Diseases. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 1086.
Fosaprepitant dimeglumine. Hoddesdon, Hertfordshire: Merck Sharp & Dohme Limited; 2008 [revised 29 Nov. 2018]. [Accessed 29 Jan. 2019] (online) Availale from:
Fosaprepitant. Highway, Greenville, NC: DSM Pharmaceuticals; 2008. [Accessed 28 Mar. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 28 Mar. 2019] (online) Available from:

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Admac Pharma Ltd
Address: SCO 84, Sector 5, Panchkula (Haryana), 134112 INDIA.

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Home

Gastro Intestinal

Other Antiemetics And Antinauseants

Fosamac 150 Injection

Fosamac 150 Injection

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Fosamac Injection

Benefits of Fosamac Injection

Side effects of Fosamac Injection

How to use Fosamac Injection

How Fosamac Injection works

All substitutes for Fosamac 150 Injection

Fosaport 150mg Injection

Fosa Injection

FOSapretero Injection

ES Pitant 150mg Injection

Apritant 150mg Injection

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Apalutamide (Oral Route)

Gliclazide (Oral Route)

Diltiazem (Oral Route)

Trabectedin (Injection Route)

Allylestrenol (Oral Route)

Frequently asked questions

What is Fosamac 150 Injection used for?

How does Fosamac 150 Injection work?

Can Fosamac 150 Injection prevent delayed vomiting after chemotherapy?

Can Fosamac 150 Injection be used for motion sickness or routine nausea?

When is Fosamac 150 Injection usually given before chemotherapy?

Can I administer Fosamac 150 Injection myself at home?

Can Fosamac 150 Injection interact with diabetes medicines such as Glimepiride or Gliclazide?

Does Fosamac 150 Injection interact with heart medicines such as Diltiazem?

What are the signs of a serious allergic reaction to Fosamac 150 Injection?

How long does the effect of Fosamac 150 Injection last?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

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