Apalutamide

Written By Dr. Subita Alagh

Reviewed By Dr. Rajeev Sharma

Last updated 30 Oct 2025 | 10:22 AM (UTC)

Apalutamide Uses

Apalutamide is used in the treatment of prostate cancer.

How Apalutamide works

Prostate cancer cells depend on androgens to grow and survive. Even in cases where the cancer becomes resistant to standard hormonal therapies (castration-resistant), androgen receptors in the cancer cells continue to be active and promote cancer growth. Apalutamide targets these androgen receptors, blocks their activation, and prevents them from binding to androgens. This action inhibits the signaling pathway that drives the growth and proliferation of prostate cancer cells.

Common side effects of Apalutamide

Joint pain, Diarrhea, Fatigue, Skin rash, High blood pressure, Flushing (sense of warmth in the face, ears, neck and trunk), Fall, Weight loss

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Medicine brands for Apalutamide

Ca APA

Maximal Healthcare Pvt Ltd

Lucien Life Sciences Private Limited

₹37500 to ₹37500

1 variant(s)

Erlamide

Sun Pharma Laboratories Ltd

₹15357 to ₹30715

2 variant(s)

Apatide

BDR Pharmaceuticals Internationals Pvt

Expert advice for Apalutamide

If you have ever experienced a seizure, you must inform your doctor!
If you have ever suffered from a brain injury, stroke (within one year), or primary brain tumor, inform your doctor.
Inform your doctor if you have a history of cardiovascular problems.
Follow your doctor's instructions regarding the dosage, timing, and duration of the treatment.
Attend all follow-up visits with your doctor as scheduled.
The doctor may monitor your liver function while you are on Apalutamide treatment, as it can affect liver enzymes.
You have been prescribed Apalutamide for the treatment of prostate cancer.
Take it with or without food, preferably at the same time every day.
Do not drive or do anything requiring concentration unless you know how Apalutamide affects you.
It may cause your skin to become light sensitive. Avoid direct exposure to excessive sunlight and use sunscreen when outdoors.
If you are diabetic, monitor your blood glucose regularly while taking Apalutamide.
Your doctor may want you to have regular blood tests to monitor your liver function while you are taking this medicine. Inform your doctor if you notice yellowing of eyes or skin, dark urine, or stomach pain.
Do not stop taking the medication without talking to your doctor first.