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Fibristal Tablet

Ulipristal acetate (5mg)
Genuine
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Fibristal Tablet is a medicine used to treat uterine fibroids (a non-cancerous growth in the uterus) in premenopausal women who cannot undergo surgical treatment or have not responded to surgical intervention.

Written By Dr. Subita Alagh, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 08 Apr 2026 | 04:53 PM (IST)
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General Information

The content is shown in English
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Product introduction

Fibristal Tablet reduces symptoms like vaginal bleeding, prolonged periods and lower back pain. It can be taken with or without food, but take it at the same time to get the most benefit. It should be taken in the dose and duration prescribed by your doctor. It is important to note that this medicine makes birth control less effective, so use proper contraceptive methods to avoid pregnancy.

This medicine's most common side effects include amenorrhea (absence of menstrual period), headache, dizziness, fatigue, and nausea. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them. Usually, your periods stop within 10 days of taking it, but if you still experience heavy bleeding, consult with your doctor. This medicine might stop your period for some time, but periods generally return within 4 weeks after the end of each treatment course.

Before taking this medicine, let your doctor know if you have had liver problems or severe asthma. Your doctor may perform regular blood tests to monitor your liver function while taking Fibristal Tablet. Inform your doctor about all other medications you are taking, as many of these may make this medicine less effective or change how it works. Inform your doctor if you are pregnant or breastfeeding.


Uses of Fibristal Tablet

Benefits of Fibristal Tablet

Uterine fibroids
Fibristal Tablet is used to treat uterine fibroids in premenopausal women by helping reduce their size and control symptoms like heavy menstrual bleeding and pelvic pain. It can improve quality of life and may reduce the need for surgery.

Side effects of Fibristal Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Fibristal
  • Absence of menstrual periods
  • Headache
  • Endometrial hyperplasia
  • Fatigue
  • Dizziness
  • Nausea

How to use Fibristal Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Fibristal Tablet may be taken with or without food.

How Fibristal Tablet works

Fibristal Tablet is a selective progesterone receptor modulator. It works by modifying the action of progesterone (natural female hormone). It is used either before surgery of fibroids or for intermittent (at regular intervals) treatment of fibroids. It helps reduce their size, stops or controls bleeding and increases your red blood cell count.

Quick tips

  • Fibristal Tablet is used for the treatment of uterine fibroids and their associated symptoms, such as painful periods, heavy bleeding and pelvic pain.
  • It considerably reduces or stops your menstrual bleeding within the first 10 days of treatment. Notify your doctor if you continue to have heavy bleeding despite taking Fibristal Tablet.
  • Your periods will usually start again within four weeks of stopping Fibristal Tablet.
  • Use a reliable barrier contraceptive method (such as condoms or a diaphragm) to prevent pregnancy while you are taking Fibristal Tablet as it may make hormonal contraceptives (such as pills) less effective.
  • Your doctor may get routine blood tests done to assess the functioning of your liver. Inform your doctor if you notice yellowing of skin/eye, dark urine, or stomach pain.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Fibristal Tablet. Please consult your doctor.
Pregnancy

Pregnancy

UNSAFE
Fibristal Tablet is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.
Breast feeding

Breast feeding

CAUTION
Fibristal Tablet should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from the body.
Driving

Driving

UNSAFE
Fibristal Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney

Kidney

SAFE IF PRESCRIBED
Fibristal Tablet is safe to use in patients with kidney disease. No dose adjustment is recommended.
Liver

Liver

CONSULT YOUR DOCTOR
There is limited data available on the use of Fibristal Tablet in patients with liver disease.

Interaction with drugs

Taking Fibristal with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Severe

Apalutamide (Oral Route)

Concomitant use should be avoided. Please consult with your doctor. Apalutamide may reduce the efficacy of Ulipristal acetate.
Severe

Armodafinil (Oral Route)

Do not consume Ulipristal acetate with Armodafinil. If Ulipristal acetate is essential, ensure a gap of At least 4 weeks after discontinuing Armodafinil. Please consult your doctor.
Severe

Bosentan (Oral Route)

Do not consume Ulipristal acetate with Bosentan. If Ulipristal acetate is essential, ensure a gap of At least 4 weeks after discontinuing Bosentan. Please consult your doctor.
Severe

Carbamazepine (Oral Route)

Do not consume Ulipristal acetate with Carbamazepine. If Ulipristal acetate is essential, ensure a gap of At least 4 weeks after discontinuing Carbamazepine. Please consult your doctor.
Severe

Dabrafenib (Oral Route)

Do not consume Ulipristal acetate with Dabrafenib. If Ulipristal acetate is essential, ensure a gap of At least 4 weeks after discontinuing Dabrafenib. Please consult your doctor.

Frequently asked questions

Fibristal Tablet acts by blocking the receptors of progesterone, which decreases the levels of progesterone and therefore it is helpful in decreasing the size of fibroids. Fibroids are non-cancerous development around the uterus. When given at a certain prescribed dose, Fibristal Tablet inhibits ovulation leading to stopping of periods. As a result, it may benefit women who have heavy bleeding due to fibroids.
No, taking a single tablet of Fibristal Tablet does not stop periods, but it may delay or prepone your periods. In some cases you may have bleeding in between your periods. Consult your doctor if this happens.
No, Fibristal Tablet cannot be used as a regular contraceptive. It is meant for occasional use as an emergency contraceptive. It is important to know that the safety and effectiveness of Fibristal Tablet have not been established for repeated use in one menstrual cycle. Hence, its repeated use is not recommended.
Fibristal Tablet should be taken orally as soon as possible after unprotected sex or contraceptive failure and not later than 120 hours (5 days). It can be taken at anytime of the day and before, during or after food. It can be taken at anytime during your menstrual cycle.
If you vomit immediately after taking Fibristal Tablet or within 3 hours of taking it, take another tablet of Fibristal Tablet. However, if you have vomited after 3 hours of taking the medicine you need not take another tablet.
Fibristal Tablet may make your birth control pills less effective and therefore in addition to birth control pills you should continue using condoms till your next period (menses).
While taking Fibristal Tablet you should be aware of some important points such as it does not work if you are already pregnant and it is not effective if you have unprotected sex after taking the tablet. It is also important to know that Fibristal Tablet does not protect against sexually transmitted diseases such as HIV, syphilis etc.

Fact Box

Chemical Class

20- oxosteroids

Habit Forming

No

Therapeutic Class

GYNAECOLOGICAL

Action Class

Selective Progesterone Receptor Modulators (SPRMs)

References

  1. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 1413.
  2. Ulipristal acetate. London: Gedeon Richter (UK) Ltd.; 2012 [revised 26 Jul. 2018]. [Accessed 03 Apr. 2019] (online) Available from:
  3. Ulipristal acetate [Prescribing Information]. Morristown, NJ: Watson Pharma, Inc.; 2010. [Accessed 20 Feb. 2024] (online) Available from:
  4. Ulipristal acetate. Ontario, Canada: Allergan Inc.; 2018.
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User feedback

Once A Day
100%
Others
90%
Emergency contraception
10%
Poor
47%
Average
28%
Excellent
25%
No Side Effect
28%
Back pain
20%
Breast tenderness
12%
Fatigue
8%
Headache
8%
With or without food
60%
With food
33%
Empty stomach
7%
Expensive
65%
Average
22%
Not Expensive
14%
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Akumentis Healthcare Ltd
Address: 204, 2nd Floor, G-Corp Tech Park, Kasarvadavali, Near Hypercity, Ghodbandar Road, Thane (West) - 400615. ,Maharashtra, India

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Fibristal Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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