


Fensupp 100 Suppository
Diclofenac (100mg)
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Fensupp 100 Suppository is a pain-relieving medicine used to treat post-operative pain and inflammation. This route is administered in cases where any other route is not possible, such as unconscious individuals or in children.
Written By Dr. Lipika Khurana, PGDHHM, BDS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 23 Sep 2025 | 05:05 PM (IST)
Written By Dr. Lipika Khurana, PGDHHM, BDS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 23 Sep 2025 | 05:05 PM (IST)
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General Information
The content is shown in English



Product introduction
Fensupp 100 Suppository should be taken in the dose and duration as advised by your doctor. It should be taken with food or milk to prevent stomach upset. Inform your doctor if you have any history of heart disease or stroke.
The most common side effects of this medicine include edema, nausea, headache, dizziness, vomiting, constipation, itching, flatulence, pain in extremity, and indigestion. Your doctor may also regularly monitor your kidney function, liver function, and levels of blood components if you are taking this medicine for long-term treatment. Long-term use may lead to serious complications such as stomach bleeding and kidney problems.
Uses of Fensupp Suppository
Benefits of Fensupp Suppository
Pain relief
Fensupp 100 Suppository belongs to a group of medicines called nonsteroidal anti-inflammatory drugs (NSAIDs). It is used for short-term relief of pain, inflammation, and swelling in conditions that affect joints and muscles. It works by blocking chemical messengers in the brain that tell us we have pain. It can help relieve pain in conditions like rheumatoid arthritis and osteoarthritis.
Take it as it is prescribed to get the most benefit. Do not take more or longer than needed as that can be dangerous. In general, you should take the lowest dose that works, for the shortest possible time. This will help you to go about your daily activities more easily and have a better, more active, quality of life.
Fensupp 100 Suppository belongs to a group of medicines called nonsteroidal anti-inflammatory drugs (NSAIDs). It is used for short-term relief of pain, inflammation, and swelling in conditions that affect joints and muscles. It works by blocking chemical messengers in the brain that tell us we have pain. It can help relieve pain in conditions like rheumatoid arthritis and osteoarthritis.
Take it as it is prescribed to get the most benefit. Do not take more or longer than needed as that can be dangerous. In general, you should take the lowest dose that works, for the shortest possible time. This will help you to go about your daily activities more easily and have a better, more active, quality of life.
Side effects of Fensupp Suppository
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Fensupp
- Diarrhea
- Flatulence
- Anal irritation
- Vomiting
- Anal itching
- Headache
- Black colored stool
- Dizziness
- Nausea
- Constipation
- Vertigo
- Abdominal pain
- Dyspepsia
- Gastrointestinal bleeding
- Gastrointestinal ulcer
- Rash
- Decreased appetite
- Application site irritation
- Increased transaminase level in blood
- Injection site pain
How to use Fensupp Suppository
Remove the wrapper from the suppository before inserting it. Keep lying down for about 15 minutes after insertion so that the suppository does not come out before it melts.
How Fensupp Suppository works
Fensupp 100 Suppository is a non-steroidal anti-inflammatory drug (NSAID) that is absorbed rapidly into the bloodstream from the rich blood supply of the rectal area. Once absorbed, it works by blocking the release of certain chemical messengers that cause pain and inflammation (redness and swelling).
All substitutes for Fensupp 100 Suppository
For information purposes only. Consult a doctor before taking any medicine.
Quick tips
- Insert Fensupp 100 Suppository gently into the rectum, pointed end first, after emptying your bowels for better absorption.
- Avoid using more than the prescribed dose, as excessive use can increase the risk of side effects.
- Lie down a few minutes after insertion to prevent the suppository from slipping out.
- If you experience severe rectal irritation or bleeding, discontinue use and consult your doctor immediately.
Safety advice

Alcohol
No interaction found/established

Pregnancy
CONSULT YOUR DOCTOR
Fensupp 100 Suppository may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding
CONSULT YOUR DOCTOR
Fensupp 100 Suppository is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving
No interaction found/established

Kidney
CONSULT YOUR DOCTOR
There is limited information available on the use of Fensupp 100 Suppository in patients with kidney disease. Please consult your doctor.

Liver
CAUTION
Fensupp 100 Suppository should be used with caution in patients with liver disease. Dose adjustment of Fensupp 100 Suppository may be needed. Please consult your doctor.
Interaction with drugs
Taking Fensupp with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Severe
Tacrolimus (Oral Route)
If concurrent use is essential, your doctor may monitor your tacrolimus levels, potassium levels and kidney function closely. They may adjust the doses as per the observations.
Severe
Methotrexate (Injection Route)
Please consult with your doctor. Doctor may monitor liver function and blood cell counts.
Severe
Fondaparinux (Injection Route)
If concurrent use is essential, watch out for bleeding and consult your doctor immediately.
Severe
Heparin (Injection Route)
Do not consume Diclofenac with Heparin. If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations. Diclofenac may increase the effect of Heparin.
Severe
Methotrexate (Injection Route)
Please consult with your doctor. Doctor may monitor liver function and blood cell counts.
Frequently asked questions
Yes, Fensupp 100 Suppository is effective when used as prescribed by your doctor. They help relieve pain and inflammation, especially in conditions like post-operative pain or arthritis. For the best results, follow the recommended dose and duration. If symptoms persist or worsen, consult your doctor.
The use of Fensupp 100 Suppository should be avoided by patients who are allergic to Fensupp 100 Suppository or any of its components. However, if you are not aware of any allergy or if you are using Fensupp 100 Suppository for the first time, consult your doctor.
You should not take Fensupp 100 Suppository during the last 3 months of pregnancy, as it may cause harmful effects on your baby. Use of Fensupp 100 Suppository can also lead to reduced labor (premature delivery). Hence, it is advised to avoid using Fensupp 100 Suppository after 6 months of pregnancy. In some cases, Fensupp 100 Suppository may be prescribed in pregnant women only if the benefits outweigh the risks involved with its use in pregnant women. If not sure, consult your doctor regarding its use.
Fensupp 100 Suppository is safe if used in the dose and duration advised by your doctor. Take it exactly as directed and do not skip any doses. Follow your doctor's instructions carefully and let your doctor know if any of the side effects bother you.
Fensupp 100 Suppository is effective in relieving pain and inflammation. It is used for various sorts of pain such as sprains, strains and other injuries. It is also helpful in various types of arthritis, gout, pain and inflammation following surgery.
No, Fensupp 100 Suppository is not a narcotic. It belongs to non-steroidal anti-inflammatory drugs (NSAIDs) group of medicines.
No, Fensupp 100 Suppository does not get you high. It does not have an abuse potential (drug-seeking behavior) and does not cause physical or psychological dependence. However, if you do not feel well, consult your doctor.
Long-term use and high doses of Fensupp 100 Suppository may cause renal problems such as protein or blood in urine and painful urination. Patients who are at maximum risk of developing kidney problems include people who are dehydrated, have heart failure, impaired kidney function, hypertension, elderly, who are on medicines which cause excess urination (diuretics), or medicines which have significant impact on kidney function. Hence, for such patients kidney function monitoring is recommended.
Fensupp 100 Suppository can cause drowsiness and also dizziness, fatigue (tiredness) and visual disturbances. However, it is not very common and may not affect everyone. If you experience these symptoms avoid driving or operating heavy machinery.
It is important to know that Fensupp 100 Suppository may increase your chance of having a heart attack or stroke. The risk is more if you take higher doses and have been using the medicine for a longer time. Also, taking Fensupp 100 Suppository may cause ulcers, bleeding, or holes in your stomach and intestine. These problems may happen without warning symptoms at any time during treatment and may even cause death. Therefore, if you encounter any such problems, consult your doctor immediately.
You should not take Fensupp 100 Suppository during the last 3 months of pregnancy as it may cause harmful effects on your baby. Use of Fensupp 100 Suppository can also lead to reduced labor (premature delivery). Hence, it is advised to avoid using Fensupp 100 Suppository during the first 6 months of pregnancy also. In some cases, Fensupp 100 Suppository may be prescribed in pregnant women only if the benefits outweigh the risks involved with its use in pregnant women. If not sure, consult your doctor regarding its use.
Fact Box
Chemical Class
Phenylacetic acid Derivative
Habit Forming
No
Therapeutic Class
PAIN ANALGESICS
Action Class
NSAID's- Non-Selective COX 1&2 Inhibitors (acetic acid)
References
- Furst DE, Ulrich RW, Varkey-Altamirano C. Nonsteroidal Anti-Inflammatory Drugs, Disease Modifying Antirheumatic Drugs, Nonopioids Analgesics, & Drugs Used in Gout. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 626.
- Grosser T, Smyth E, FitzGerald GA. Anti-Inflammatory, Antipyretic, and Analgesic Agents; Pharmacotherapy of Gout. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 986-87.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 295-97.
- Diclofenac [EMC Label]. Camberley, Surrey: Novartis Pharmaceuticals UK Ltd.; 1997 [revised 30 Mar. 2017]. [Accessed 02 Apr. 2019] (online) Available from:
- Diclofenac [Product Information Leaflet]. Andheri (East), Mumbai: Bliss GVS Pharma Ltd.; 2022. [Accessed 06 Apr. 2024] (online) Available from:
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User feedback
Pain relief
40%
Others
20%
Pain during menstruation
20%
Musculo-skeletal pain
20%
Excellent
67%
Average
33%
No Side Effect
100%
With or without food
100%
Average
50%
Not Expensive
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
Marketer details
Name: Meridian Enterprises Pvt Ltd
Address: 1108, Embassy Centre, Nariman Point, Mumbai 400 021. India.
Address: 1108, Embassy Centre, Nariman Point, Mumbai 400 021. India.
Vendor Details
Country of origin: India
Lab tests offered by us
- CBC (Complete Blood Count)
- FBS (Fasting Blood Sugar)
- Thyroid Profile Total (T3, T4 & TSH)
- HbA1c (Glycosylated Hemoglobin)
- PPBS (Postprandial Blood Sugar)
- Lipid Profile
- Vitamin D (25-Hydroxy)
- Urine R/M (Urine Routine & Microscopy)
- Coronavirus Covid -19 test- RT PCR
- LFT (Liver Function Test)
- KFT (Kidney Function Test)
- TSH (Thyroid Stimulating Hormone) Ultrasensitive
- ESR (Erythrocyte Sedimentation Rate)
- Uric Acid, Serum
- Vitamin B12
- CRP (C-Reactive Protein), Quantitative
- Urine C/S (Urine Culture and Sensitivity)
- Serum Electrolytes
- Serum Calcium
- Serum Creatinine
- Diabetes Screening (HbA1C & Fasting Sugar)
- KFT with Electrolytes (Kidney Function Test with Electrolytes)
- Cholesterol - Total
- Hb (Hemoglobin)
- Complete Hemogram (CBC & ESR)
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