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Jonac 100mg Suppository

Diclofenac (100mg)

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Jonac 100mg Suppository is a pain-relieving medicine used to treat post-operative pain and inflammation. This route is administered in cases where any other route is not possible, such as unconscious individuals or in children.

Written By Dr. Lipika Khurana, PGDHHM, BDS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 16 Mar 2026 | 04:08 PM (IST)

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General Information

Contains

Diclofenac (100mg)

Marketer

Zydus Cadila

Storage

Store below 30°C

The content is shown in English

Product introduction

Jonac 100mg Suppository should be taken in the dose and duration as advised by your doctor. It should be taken with food or milk to prevent stomach upset. Inform your doctor if you have any history of heart disease or stroke.
The most common side effects of this medicine include edema, nausea, headache, dizziness, vomiting, constipation, itching, flatulence, pain in extremity, and indigestion. Your doctor may also regularly monitor your kidney function, liver function, and levels of blood components if you are taking this medicine for long-term treatment. Long-term use may lead to serious complications such as stomach bleeding and kidney problems.

Uses of Jonac Suppository

Pain relief

Benefits of Jonac Suppository

Pain relief
Jonac 100mg Suppository belongs to a group of medicines called nonsteroidal anti-inflammatory drugs (NSAIDs). It is used for short-term relief of pain, inflammation, and swelling in conditions that affect joints and muscles. It works by blocking chemical messengers in the brain that tell us we have pain. It can help relieve pain in conditions like rheumatoid arthritis and osteoarthritis.

Take it as it is prescribed to get the most benefit. Do not take more or longer than needed as that can be dangerous. In general, you should take the lowest dose that works, for the shortest possible time. This will help you to go about your daily activities more easily and have a better, more active, quality of life.

Side effects of Jonac Suppository

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Jonac

Diarrhea
Flatulence
Anal irritation
Vomiting
Anal itching
Headache
Black colored stool
Dizziness
Nausea
Constipation
Vertigo
Abdominal pain
Dyspepsia
Gastrointestinal bleeding
Gastrointestinal ulcer
Rash
Decreased appetite
Application site irritation
Increased transaminase level in blood
Injection site pain

How to use Jonac Suppository

Remove the wrapper from the suppository before inserting it. Keep lying down for about 15 minutes after insertion so that the suppository does not come out before it melts.

How Jonac Suppository works

Jonac 100mg Suppository is a non-steroidal anti-inflammatory drug (NSAID) that is absorbed rapidly into the bloodstream from the rich blood supply of the rectal area. Once absorbed, it works by blocking the release of certain chemical messengers that cause pain and inflammation (redness and swelling).

All substitutes for Jonac 100mg Suppository

For information purposes only. Consult a doctor before taking any medicine.

Dynapar 100mg Suppository

by Troikaa Pharmaceuticals Ltd.

₹17.53/suppository

41% cheaper

Justin 100mg Suppository

by Neon Laboratories Ltd

₹18.74/suppository

37% cheaper

Quick tips

Insert Jonac 100mg Suppository gently into the rectum, pointed end first, after emptying your bowels for better absorption.
Avoid using more than the prescribed dose, as excessive use can increase the risk of side effects.
Lie down a few minutes after insertion to prevent the suppository from slipping out.
If you experience severe rectal irritation or bleeding, discontinue use and consult your doctor immediately.

Safety advice

Alcohol

No interaction found/established

Pregnancy

CONSULT YOUR DOCTOR

Jonac 100mg Suppository is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding

UNSAFE

Jonac 100mg Suppository is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving

No interaction found/established

Kidney

CAUTION

Jonac 100mg Suppository should be used with caution in patients with kidney disease. Dose adjustment may be needed.

Liver

CAUTION

Jonac 100mg Suppository should be used with caution in patients with liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Jonac with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Severe

Tacrolimus (Oral Route)

If concurrent use is essential, your doctor may monitor your tacrolimus levels, potassium levels and kidney function closely. They may adjust the doses as per the observations.

Severe

Methotrexate (Injection Route)

Please consult with your doctor. Doctor may monitor liver function and blood cell counts.

Severe

Fondaparinux (Injection Route)

If concurrent use is essential, watch out for bleeding and consult your doctor immediately.

Severe

Heparin (Injection Route)

Do not consume Diclofenac with Heparin. If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations. Diclofenac may increase the effect of Heparin.

Severe

Methotrexate (Injection Route)

Please consult with your doctor. Doctor may monitor liver function and blood cell counts.

Frequently asked questions

Is Jonac 100mg Suppository effective?

Yes, Jonac 100mg Suppository is effective when used as prescribed by your doctor. They help relieve pain and inflammation, especially in conditions like post-operative pain or arthritis. For the best results, follow the recommended dose and duration. If symptoms persist or worsen, consult your doctor.

In which conditions is the use of Jonac 100mg Suppository avoided?

The use of Jonac 100mg Suppository should be avoided by patients who are allergic to Jonac 100mg Suppository or any of its components. However, if you are not aware of any allergy or if you are using Jonac 100mg Suppository for the first time, consult your doctor.

Can Jonac 100mg Suppository be used during pregnancy?

You should not take Jonac 100mg Suppository during the last 3 months of pregnancy, as it may cause harmful effects on your baby. Use of Jonac 100mg Suppository can also lead to reduced labor (premature delivery). Hence, it is advised to avoid using Jonac 100mg Suppository after 6 months of pregnancy. In some cases, Jonac 100mg Suppository may be prescribed in pregnant women only if the benefits outweigh the risks involved with its use in pregnant women. If not sure, consult your doctor regarding its use.

Is Jonac 100mg Suppository safe?

Jonac 100mg Suppository is safe if used in the dose and duration advised by your doctor. Take it exactly as directed and do not skip any doses. Follow your doctor's instructions carefully and let your doctor know if any of the side effects bother you.

Is Jonac 100mg Suppository a good painkiller?

Jonac 100mg Suppository is effective in relieving pain and inflammation. It is used for various sorts of pain such as sprains, strains and other injuries. It is also helpful in various types of arthritis, gout, pain and inflammation following surgery.

Is Jonac 100mg Suppository a narcotic?

No, Jonac 100mg Suppository is not a narcotic. It belongs to non-steroidal anti-inflammatory drugs (NSAIDs) group of medicines.

Does Jonac 100mg Suppository get you high?

No, Jonac 100mg Suppository does not get you high. It does not have an abuse potential (drug-seeking behavior) and does not cause physical or psychological dependence. However, if you do not feel well, consult your doctor.

Can Jonac 100mg Suppository damage your kidneys?

Long-term use and high doses of Jonac 100mg Suppository may cause renal problems such as protein or blood in urine and painful urination. Patients who are at maximum risk of developing kidney problems include people who are dehydrated, have heart failure, impaired kidney function, hypertension, elderly, who are on medicines which cause excess urination (diuretics), or medicines which have significant impact on kidney function. Hence, for such patients kidney function monitoring is recommended.

Does Jonac 100mg Suppository make you drowsy?

Jonac 100mg Suppository can cause drowsiness and also dizziness, fatigue (tiredness) and visual disturbances. However, it is not very common and may not affect everyone. If you experience these symptoms avoid driving or operating heavy machinery.

What is the most important information I need to know about Jonac 100mg Suppository?

It is important to know that Jonac 100mg Suppository may increase your chance of having a heart attack or stroke. The risk is more if you take higher doses and have been using the medicine for a longer time. Also, taking Jonac 100mg Suppository may cause ulcers, bleeding, or holes in your stomach and intestine. These problems may happen without warning symptoms at any time during treatment and may even cause death. Therefore, if you encounter any such problems, consult your doctor immediately.

Can Jonac 100mg Suppository be taken during pregnancy?

You should not take Jonac 100mg Suppository during the last 3 months of pregnancy as it may cause harmful effects on your baby. Use of Jonac 100mg Suppository can also lead to reduced labor (premature delivery). Hence, it is advised to avoid using Jonac 100mg Suppository during the first 6 months of pregnancy also. In some cases, Jonac 100mg Suppository may be prescribed in pregnant women only if the benefits outweigh the risks involved with its use in pregnant women. If not sure, consult your doctor regarding its use.

Fact Box

Chemical Class

Dichlorobenzenes

Habit Forming

Therapeutic Class

PAIN ANALGESICS

Action Class

NSAID's- Non-Selective COX 1&2 Inhibitors (acetic acid)

References

Furst DE, Ulrich RW, Varkey-Altamirano C. Nonsteroidal Anti-Inflammatory Drugs, Disease Modifying Antirheumatic Drugs, Nonopioids Analgesics, & Drugs Used in Gout. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 626.
Grosser T, Smyth E, FitzGerald GA. Anti-Inflammatory, Antipyretic, and Analgesic Agents; Pharmacotherapy of Gout. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 986-87.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 295-97.
Diclofenac [EMC Label]. Camberley, Surrey: Novartis Pharmaceuticals UK Ltd.; 1997 [revised 30 Mar. 2017]. [Accessed 02 Apr. 2019] (online) Available from:
Diclofenac [Product Information Leaflet]. Andheri (East), Mumbai: Bliss GVS Pharma Ltd.; 2022. [Accessed 06 Apr. 2024] (online) Available from:

User feedback

Patients taking Jonac 100mg Suppository

Once A Day

81%

Once A Week

Four Times A Day

Twice A Day

What are you using Jonac Suppository for?

Pain relief

43%

Others

39%

Musculo-skeletal pain

13%

Rheumatic pain

How much was the improvement?

Excellent

42%

Average

38%

Poor

21%

What were the side-effects while using Jonac 100mg Suppository?

Burning sensation

50%

No Side Effect

50%

How do you take Jonac Suppository?

With or without food

67%

Empty stomach

33%

Please rate Jonac 100mg Suppository on price

Expensive

83%

Average

17%

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Zydus Cadila
Address: Zydus Tower, Satellite Cross Roads,Ahmedabad – 380015 Gujarat, India.

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Jonac 100mg Suppository. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

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Why we need a prescription?

Jonac 100mg Suppository

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General Information

Contains

Marketer

Storage

Product introduction

Uses of Jonac Suppository

Benefits of Jonac Suppository

Side effects of Jonac Suppository

How to use Jonac Suppository

How Jonac Suppository works

All substitutes for Jonac 100mg Suppository

Dynapar 100mg Suppository

Justin 100mg Suppository

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Tacrolimus (Oral Route)

Methotrexate (Injection Route)

Fondaparinux (Injection Route)

Heparin (Injection Route)

Methotrexate (Injection Route)

Frequently asked questions

Is Jonac 100mg Suppository effective?

In which conditions is the use of Jonac 100mg Suppository avoided?

Can Jonac 100mg Suppository be used during pregnancy?

Is Jonac 100mg Suppository safe?

Is Jonac 100mg Suppository a good painkiller?

Is Jonac 100mg Suppository a narcotic?

Does Jonac 100mg Suppository get you high?

Can Jonac 100mg Suppository damage your kidneys?

Does Jonac 100mg Suppository make you drowsy?

What is the most important information I need to know about Jonac 100mg Suppository?

Can Jonac 100mg Suppository be taken during pregnancy?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

References

User feedback

Patients taking Jonac 100mg Suppository

What are you using Jonac Suppository for?

How much was the improvement?

What were the side-effects while using Jonac 100mg Suppository?

How do you take Jonac Suppository?

Please rate Jonac 100mg Suppository on price

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

In case of any issues, contact us

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