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Eflemac 600mg Tablet

Written By Dr. Sakshi Jain, MS, BDS
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS
Last updated on 13 Mar 2026 | 01:39 PM (IST)
Eflemac 600mg Tablet belongs to a group of medicines called antiretrovirals. It is used to treat HIV (human immunodeficiency virus), the virus that can cause AIDS (acquired immunodeficiency syndrome). It helps to control HIV infection so your immune system can work better.
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Eflemac 600mg Tablet
Eflemac 600mg Tablet
bottle of 30 tablets
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Efavir 600 Tablet
Efavir 600 Tablet
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Eflemac 600mg Tablet image
Eflemac 600mg Tablet image

Product introduction

Eflemac 600mg Tablet reduces the chances of getting HIV-related complications and improves your lifespan. It can be taken empty stomach or with food and is prescribed in combination with other HIV medicines. Taking all these medicines regularly at the right times greatly increases their effectiveness and reduces the chances of HIV becoming resistant to them. It is important to keep taking them regularly until your doctor tells you it is safe to stop.

Common side effects of this medicine include headache, nausea, vomiting, stomach pain, fatigue, diarrhea, and rash. These are usually not serious but tell your doctor if they bother you or do not go away. Consult your doctor urgently if you experience a skin reaction or liver damage. 

Before taking it, tell your doctor if you have any skin, liver, or kidney problems. While using it, you may need regular blood tests to check your blood cell counts and liver function. Avoid drinking alcohol as it may increase your risk of liver damage. Pregnant or breastfeeding mothers should consult their doctor before using this medicine. Do not have unprotected sex or share personal items like razors or toothbrushes, if you are HIV positive. Talk to your doctor about safe ways like condoms to prevent HIV transmission during sex.

Uses of Eflemac Tablet

Benefits of Eflemac Tablet

HIV infection
Eflemac 600mg Tablet is used as part of antiretroviral therapy to manage HIV infection. It helps lower the amount of virus in the body, supports the immune system, and reduces the risk of HIV-related complications. When taken consistently, it can improve long-term health and lower the chances of transmitting the virus to others.

Side effects of Eflemac Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Eflemac
  • Fatigue
  • Pain
  • Decreased appetite
  • Headache
  • Nausea
  • Dizziness
  • Vomiting
  • Increased liver enzymes
  • Insomnia (difficulty in sleeping)
  • Sleepiness
  • Abnormal dreams
  • Anxiety
  • Itching
  • Difficulty in paying attention
  • Rash
  • Abdominal pain
  • Diarrhea
  • Depression

How to use Eflemac Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Eflemac 600mg Tablet is to be taken on an empty stomach.

How Eflemac Tablet works

Eflemac 600mg Tablet prevents the multiplication of HIV virus in human cells, thereby stopping the HIV virus from producing new viruses.

Quick tips

  • Eflemac 600mg Tablet is used in combination with other medicines for the treatment of HIV (human immunodeficiency virus).
  • Take it on an empty stomach, preferably at bedtime to reduce side effects.
  • Do not skip any doses and finish the full course of treatment even if you feel better.
  • You can also pass on HIV or HBV to others. Don't share needles or personal items that can have blood or body fluids on them.
  • Your doctor may check your liver function regularly. Inform your doctor if you notice yellowing of eyes or skin, dark urine, or stomach pain.
  • You might experience dizziness or abnormal dreams during initial days of treatment. Consult with a doctor if it bothers you or does not go away. 
  • Use a reliable method of contraception to prevent pregnancy while taking this medicine.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Eflemac 600mg Tablet. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Eflemac 600mg Tablet is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Eflemac 600mg Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.
Driving

Driving

UNSAFE
Eflemac 600mg Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney

Kidney

SAFE IF PRESCRIBED
Eflemac 600mg Tablet is probably safe to use in patients with kidney disease. Limited data suggest dose adjustment may not be needed.
Liver

Liver

UNSAFE
Eflemac 600mg Tablet is unsafe to use in patients with liver disease and should be avoided.
Use of Eflemac 600mg Tablet is not recommended in patients with moderate and severe liver disease.

Interaction with drugs

Taking Eflemac with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Life-threatening

Ranolazine (Oral Route)

Do not consume Ranolazine with Efavirenz.
Life-threatening

Aripiprazole (Oral Route)

Do not consume Aripiprazole with Efavirenz.
Life-threatening

Pimozide (Oral Route)

Do not consume Pimozide with Efavirenz.
Life-threatening

Amiodarone (Oral Route)

Do not consume Efavirenz with Amiodarone.
Life-threatening

Amiodarone (Injection Route)

Do not consume Efavirenz with Amiodarone.

Frequently asked questions

Eflemac 600mg Tablet belongs to a group of medicines called antiretrovirals. It is used to treat human immunodeficiency virus (HIV), which if not controlled can cause AIDS (acquired immunodeficiency syndrome). It helps to control HIV infection so your immune system can work better.
Eflemac 600mg Tablet is safe if used in the dose and duration advised by your doctor. Take it exactly as directed and do not skip any dose. Follow your doctor's instructions carefully and let your doctor know if any of the side effects bother you.
Eflemac 600mg Tablet works by blocking the function of an enzyme, called reverse transcriptase, which is responsible for the HIV replication process. This helps to reduce the level of HIV in the blood.
Eflemac 600mg Tablet is effective if used in the dose and duration advised by your doctor. Do not stop taking it even if you see improvement in your condition. If you stop using Eflemac 600mg Tablet too early, the symptoms may return or worsen.
If you forget a dose of Eflemac 600mg Tablet, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take the next scheduled dose in the prescribed time. Do not double the dose to make up for the missed one as this may increase the chances of developing side effects.
No, Eflemac 600mg Tablet is not safe to be taken in pregnancy. Some animal studies have shown that Eflemac 600mg Tablet may cause birth defects if given to pregnant mothers. Therefore, it is advisable not to take Eflemac 600mg Tablet if you are pregnant, planning to conceive or breastfeeding.

Fact Box

Chemical Class

Benzoxazines

Habit Forming

No

Therapeutic Class

ANTI INFECTIVES

Action Class

Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTIs)

References

  1. Flexner C. Antiretroviral Agents and Treatment of HIV Infection. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. pp. 1643-644.
  2. Safrin S. Antiviral Agents. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 861-62..
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 455-56.
  4. Efavirenz. South Ruislip, Middlesex: Aurobindo Pharma - Milpharm Ltd.; 2014 [revised 10 Dec. 2018]. [Accessed 25 Jan. 2019] (online) Available from:
  5. Efavirenz. Princeton, New Jersey: Bristol-Myers Squibb Company; 1998 [revised Sep. 2011]. [Accessed 31 Mar. 2019] (online) Available from:
  6. Central Drugs Standard Control Organisation (CDSCO). [Accessed 31 Mar. 2019] (online) Available from:
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Macleods Pharmaceuticals Pvt Ltd
Address: Atlanta Arcade, Marol Church Road, Andheri (East), Mumbai - 400059, INDIA.

Vendor Details

Country of origin: India
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