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Dothivin 50 mg Tablet

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Overview

Uses of Dothivin Tablet

Dothivin 50 mg Tablet is used in the treatment of depression, neuropathic pain and anxiety disorder. It is used in patients intolerant of or unresponsive to alternative treatment options for depression.

Dothivin Tablet side effects

Common
  • Dryness in mouth
  • Blurred vision
  • Sleepiness
  • Increased heart rate
  • Orthostatic hypotension (sudden lowering of blood pressure on standing)
  • Weight gain
  • Difficulty in urination
  • Constipation

How to use Dothivin Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Dothivin 50 mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Dothivin Tablet works

Dothivin 50 mg Tablet increases the levels of chemical messengers in the brain that help in regulating the mood and treat depression.

Dothivin Tablet related warnings

Alcohol
Interaction with alcohol is unknown. Please consult your doctor.
Pregnancy
WEIGH RISKS VS BENEFITS
Dothivin 50 mg Tablet may be unsafe to use during pregnancy.
Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
Lactation
CAUTION
Dothivin 50 mg Tablet is probably unsafe to use during lactation. Limited human data suggest that the drug could represent a significant risk to the baby.
Driving
It is not known whether Dothivin 50 mg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney
There is limited information available on the use of Dothivin 50 mg Tablet in patients with kidney disease. Please consult your doctor.
However, some studies suggest a cautious use of this medicine in patients with kidney disease.
Liver
There is limited information available on the use of Dothivin 50 mg Tablet in patients with liver disease. Please consult your doctor.

What if you miss a dose of Dothivin Tablet?

If you miss a dose of Dothivin 50 mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Dothivin 50 mg Tablet
₹3/Tablet
Dothip 50mg Tablet
Micro Labs Ltd
₹6.7/Tablet
123% costlier
Prothiaden 50 Tablet
Abbott
₹14.51/Tablet
384% costlier
Dotin 50mg Tablet
Tas Med India Pvt Ltd
₹6.15/Tablet
105% costlier
Dozep 50mg Tablet
Talent India
₹5.94/Tablet
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DO RE ME 50mg Tablet
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₹5.7/Tablet
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Expert Advice

  • The main dose should be taken at night as this drug may produce drowsiness or sleepiness.
  • It can take 4 to 6 weeks for Dothivin 50 mg Tablet to start working.
  • You should continue the treatment for at least 6 months after you feel better to stop depression from coming back.
  • If your doctor asks you to stop Dothivin 50 mg Tablet, you should reduce the dose slowly over 4 weeks. You should not discontinue it abruptly.
  • Avoid driving or operating machinery as it may decrease alertness.
  • Avoid consuming alcohol when taking the Dothivin 50 mg Tablet, as it may cause excessive drowsiness and calmness.
  • The addiction/dependence potential of Dothivin 50 mg Tablet is very less.
  • It may be extremely dangerous in overdose.

Interaction with Drugs

Taking Dothivin with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Lithium carbonate
Brand(s): Psycolith
SERIOUS
Tramadol
Brand(s): Tremash
SERIOUS
Phenobarbitone
Brand(s): Shinosun
SERIOUS
Paroxetine
Brand(s): Leparox, Prx
SERIOUS
Venlafaxine
Brand(s): Vlx
SERIOUS
Clonazepam
Brand(s): Panik
SERIOUS
Lorazepam
Brand(s): Psycopan
SERIOUS
Clobazam
Brand(s): Risure
SERIOUS
Sertraline
Brand(s): Zosert
SERIOUS
Alprazolam
Brand(s): Eurolam
SERIOUS
View all interactions

Patient Concerns

Questions Related to Dothivin

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I am prescribed Lonazep MD 0.5mg twice a day for anxiety. Its causing me depression. Is there any other GABA medication that is not addictive and does not results in depression?
Dr. Ambrish Dharmadhikari
Mental Wellness
Benzodiazepines are usually do not cause depressionSerotonin and norepinephrine reuptake inhibitors are commonly used in anxiety disorderAs well as depression
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Hi my name is PATIENT i was always a weak kid in school growing up my parents got seperated,leading my mother basically abandoning me after grade 5.I could never concentrate in school and i always wanted to be outdoors and my marks were terrible ! but anyway in the up-coming years i shifted a lot of shcools had a lot of failures and identety crises could never really calm down and figure what the problem is at the age of 20 i started working at an IT company which was really hard for me to get into but basically a job that i loved ! i was good at it too then i got sacked because i wasn't being able to concentrate again and i started losing interest.Well coming to the point i started seeing my first psycatrist in a year ago and he said i just had genralized anxiety disorder which i was given medication for but didn't solve my depression at all then i went to someone i was diagnosed with add but my main problem as if now is that i was on dazzle 20-30 mg for 15 days and it made me feel too drowzy and slow and blocked my thoughts now my doctor has percribed pregawave-m,S methiwave-400 and vilamid-20 but i haven't had them because I'm scared of the side effects my questions are :- 1. Can i consume alcahol with this drug combination ? 2. is there something more lighter ? 3.is ayurveda better ? 4.and does clinical depression wave off and how long do i take the meds ?
Dr. Jyoti Kapoor Madan
Psychiatrist
1. It is not advisable to take alcohol with medicines. 2. There is no heavy or light medicines. It's individual body's pharmacokinetic response. What suits one may not suit another. If you are having side effects, your psychiatrist can modify regimen accordingly. 3. A qualified Ayurvedacharya will know if he/ she can treat your condition. There are no comparative research studies between Ayurvedic and allopathic regimens to conclude if one is better than the other but as an Allopathy practitioner, I find satisfactory response with psychotropics. 4. Depression and anxiety are neurochemical responses to emetic and environmental factors. Treatment includes both medicines and psychotherapy for developing positive coping skills. Duration and response depend on a number of factors like history, symptom severity, duration and individual personality. Only time will tell if one is completely cured with or without medicines.
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FAQs

Q. Is Dothivin a sedative?

No. Dothivin is an antidepressant (TCA) that is used to treat depression, nerve pain, and anxiety disorder. It can cause drowsiness or sedation as a side effect. Therefore caution is advised when driving or operating dangerous machinery and even when getting out of bed at night.

Q. Is Dothivin a muscle relaxant?

No. Dothivin is not a muscle relaxant. It is a tricyclic antidepressant (TCA) used in the treatment of depression, nerve pain, and anxiety disorder.

Q. What is the difference between Dothivin and amitriptyline?

Dothivin is chemically related to Amitriptyline and both are tricyclic antidepressant (TCA) medicine. There is overlap in pharmacological property of this medicine.

Q. Is Dothivin the same as doxepin?

Dothivin and doxepin are different medicines but belong to the similar chemical class. Doxepin, at low doses, can improve sleep in patients with insomnia. It is also available in the topical form for use in various neuro-dermatitis syndrome, especially itching.

Q. How to stop Dothivin?

If your doctor asks you to stop Dothivin, you should reduce the dose slowly over 4 weeks. You should not discontinue it abruptly. Sudden discontinuation may cause aggression, anxiety, blurred vision, concentration impairment, constipation and crying spell.

Q. Is Dothivin fatal?

Yes. Dothivin can be fatal (can cause death) in overdose. This is due to a life-threatening or dangerous side effect in overdose like hyperthermia, seizure, arrhythmia, tachycardia, orthostatic hypotension or sudden death. That's why it is generally not considered a first-line option for depression because of side effect profile.

Q. Can Dothivin be used along with mirtazapine?

It is better to avoid Dothivin with mirtazapine. Mirtazapine, which is used in the treatment of depression, can potentiate the sedative effects of Dothivin.

Q. Can Dothivin be used with citalopram?

No. Citalopram and Dothivin both are the antidepressant. Citalopram may increase the high blood level of Dothivin. This may lead to a life-threatening or dangerous side effect of hyperthermia, seizure, arrhythmia, tachycardia, orthostatic hypotension or sudden death.

Q. Can Dothivin be used with sertraline?

No. Sertraline and Dothivin both are the anti-depressant. Sertraline may increase the high blood level of Dothivin. This may lead to a life-threatening or dangerous side effect of hyperthermia, seizure, arrhythmia, tachycardia, orthostatic hypotension or sudden death.

Q. Can I take Dothivin with diazepam?

It is better to avoid this combination. Diazepam is a sedative drug and Dothivin may cause sedation as a side effect too. Taking both of them together can increase the drowsiness or sleepiness. Inform your doctor if you are taking diazepam.

Q. Can Dothivin be used in the treatment of trigeminal neuralgia?

No. Dothivin is not approved for the treatment of trigeminal neuralgia. Trigeminal neuralgia is a chronic pain condition that affects the trigeminal or 5th cranial nerve, one of the most widely distributed nerves in the head.

Q. Can Dothivin be used in the treatment of burning mouth syndrome?

No. Dothivin is not approved for the treatment of burning mouth syndrome. Burning mouth syndrome is a painful condition of mouth that is burning, scalding, tingling or feeling of numbness that may occur every day for months or longer.

Q. Can I take Dothivin for depression?

Yes. Dothivin is indicated for the treatment of depression. It has a potential advantage in the patient with depression if associated with insomnia and anxiety. It is generally not considered a first-line option for depression because of side effect profile but very useful for severe or treatment-resistant depression.

Q. Can Dothivin used to treat IBS (Irritable Bowel Syndrome)?

No. Dothivin is not approved for the treatment of Irritable Bowel Syndrome (IBS). Irritable Bowel Syndrome is a functional gastrointestinal disorder characterised by chronic or recurrent abdominal pain or discomfort associated with altered bowel habits.

Q. Can Dothivin be used to treat insomnia with depression?

Yes. Dothivin may be used for the treatment of insomnia (too much arousal both at night and during the day) associated with depression. Because it can cause drowsiness or sedation as side effects, it is effective in treating insomnia associated with depression.

Q. Can I use Dothivin for fibromyalgia?

Yes. Dothivin is not approved for the treatment of fibromyalgia. Fibromyalgia is a pain syndrome with tenderness but no structural pathology in muscles, ligamanets or joints.

Q. Can I use Dothivin for nerve pain?

Yes. Dothivin is indicated for the treatment of nerve pain/neuropathic pain. Chronic pain/Neuropathic pain is described as pain that arises from damage to, or dysfunction of, any part of peripheral or central nervous system. It is associated with the disease which can affect nerves like diabetes mellitus or herpes infections.

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Manufacturer/Marketer Address
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