Dothivin 50 mg Tablet is a prescription medicine used in the treatment of depression, neuropathic pain, and anxiety disorder. It is used in patients intolerant of or unresponsive to alternative treatment options for depression.

Dothivin 50 mg Tablet works by increasing the level of chemical messengers in the brain that help in regulating mood. It is taken by mouth with or without food and preferably at night. Take it at a fixed time each day to maintain consistent level of medicine in the blood. If you have missed a dose, take it as soon as you remember it. You should never skip any doses and finish full course of treatment even if you feel better. It is important that this medication is not stopped suddenly without talking to doctor as it may worsen your symptoms. Remember to take this medicine as advised by doctor only as it can be extremely dangerous in overdose.

Some common side effects of this medicine includes dryness in mouth, blurred vision, and increased heart rate. Initially, this medicine may cause sudden drop in the blood pressure when you change positions, rise slowly if you have been sitting or lying down. It even causes dizziness and sleepiness, do not drive or do anything that requires mental focus until you know how this medicine affects you. This medicine may cause weight gain and to control it, you should have a balanced diet and exercise regularly.

Uses of Dothivin Tablet

Anxiety disorder

Dothivin Tablet side effects

Common

Dryness in mouth
Increased heart rate
Orthostatic hypotension (sudden lowering of blood pressure on standing)
Weight gain
Difficulty in urination
Constipation

How to use Dothivin Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Dothivin 50 mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Dothivin Tablet works

Dothivin 50 mg Tablet increases the levels of chemical messengers in the brain that help in regulating the mood and treat depression.

Dothivin Tablet related warnings

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Dothivin 50 mg Tablet. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Dothivin 50 mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Lactation

CONSULT YOUR DOCTOR

Dothivin 50 mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

CONSULT YOUR DOCTOR

It is not known whether Dothivin 50 mg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.

Kidney

CONSULT YOUR DOCTOR

There is limited information available on the use of Dothivin 50 mg Tablet in patients with kidney disease. Please consult your doctor.
However, some studies suggest a cautious use of this medicine in patients with kidney disease.

Liver

CONSULT YOUR DOCTOR

There is limited information available on the use of Dothivin 50 mg Tablet in patients with liver disease. Please consult your doctor.

What if you miss a dose of Dothivin Tablet?

If you miss a dose of Dothivin 50 mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.

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Interaction with Drugs

Taking Dothivin with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Alprazolam

Brand(s): Eurolam

SERIOUS

Tramadol

Brand(s): Tremash

SERIOUS

Paroxetine

Brand(s): Leparox, Prx

SERIOUS

Clonazepam

Brand(s): Panik

SERIOUS

Clobazam

Brand(s): Risure

SERIOUS

Lithium carbonate

Brand(s): Psycolith

SERIOUS

Venlafaxine

Brand(s): Vlx

SERIOUS

Phenobarbitone

Brand(s): Shinosun

SERIOUS

Lorazepam

Brand(s): Psycopan

SERIOUS

Sertraline

Brand(s): Zosert

SERIOUS

View all interactions

Patient Concerns

Questions Related to Dothivin

I have hyperacidity pitta gas due to which i have high blood pressure and anxiety disorder some time whwn there is no gas my bp comes normal doctor has given me telpress ct 40 how can the bp come in control and all report are normalMy bp was 160/100

Dr. Aanchal Maheshwari

Ayurveda

Take avipattikar churan 1 spoon twice with water before meal, kaam dudha ras 1 tab twice, brahmi vati 2 tablet twice with water

sir if i mastribute 2 times per day i got nervou and muscle tightness sleepinessand eyes was paining (litle bit) and i have anxiety disorder using tabs from 20 days

Dr. Pranay Gandhi

Sexologist

1.stop smoking and alcohol 2.join a gym and reduce weight. Do weight lifting exercises. 3.tablet sildenafil or viagra 1 tablet 1 hour before sexual activity. 4.Get tested so that u don?t have any of the following causes: 1.heart diseases 2. diabetes 3.neurological problems 4.hormonal problems 5.drug side effects

Hello sir, I have been taking tablets for anxiety and depression for last one year. Gradually my doctor decreased dosage. Now iam using stresloc, Opiprol(antidepressant), and Alzolam 0.5. With capi gold vitamin tablet.I have generalised anxiety disorder. Six days ago I dint take that stresloc tablet. It's a combination of alprazolam and propranolol. And it's for morning and night. I decided to skip the morning dosage. First day I dint feel anything. But I couldn't sleep well. Second day I was feeling migraine in head. Anxiety has increased. On that day night I felt there was a fluid running in my head. At that same time , I heard some insect sounds coming from my head. It means insects are produced sound at night time and it's pitch level is high. That sound disturbed me a lot and my concentration was always on that. Before that incident I was watching movie through headphone with full sound in my mobile. I always used to watch movies or videos using headphone with full sound . After that incident I used to take that morning dosage also. Anxiety has controlled but still that ringing sound disturbed at some time . Not all time. My question is that ringing sound produced by any ear problem or that anxiety effects. Plz reply fast ly bcoz it affects my concentration Is that ear problem or anxiety effects??

Dr. Vijay Verma

Ear Nose Throat Specialist

See both ear and anxiety issues can cause ringing better get audiometry test if it is normal than ringing is due to anxiety

What is the best ayurvedic medicine for lethargy,dullness,obsessive compulsive disorder, bipolar mood disorder,general anxiety disorder,gas,bloating,low digestive strength,low body energy,low concentration,too much attachment and paranoid behavior?

Dr. Deepak Kumar Soni

Skin Specialist

https://www.1mgayush.com/otc/jiva-ashwagandha-tablet-otc3299671-1 Tablet after lunch & dinner, Take at least 1-2 months.

Having anxiety disorder and depression for the last 4 yrs undergone course for the same but symptoms persist and now having more negative feelings now taking peroxtine release and cloanezapam tablet daily night Suggest cure in homeopath.

Dr. Saurav Arora

Homeopathy

In your case I advise you to visit a homeopathic doctor and take treatment under supervision. In homeopathy symptoms, history and examination is very important. In majority of cases, after a long case taking and case workout, we try to select a constitutional remedy which is used to treat the disease from its root cause. Taking a constitutional treatment shall also take care the reoccurrence of disease.

I am suffering from anxiety disorder and panic disorder since 2009 I was prescribed with clonazepam 1mg-3times a day and cita s 20mg-while a day From 2 weeks I'm getting suicidal thoughts If I stop any one tablet a day I'm getting sick from next day Please suggest me what I have to do. ??

Dr. Jyoti Kapoor Madan

Psychiatrist

Maximum therapeutic dose of Clonazepam is 2mg/day for not more than 4-6weeks. Medicines are optimised till the response come and anxiolytics are generally tapered of. You are expected to maintain regular follow up with your psychiatrist. Current symptoms are suggestive of mood disorder and you need to see your psychiatrist asap so that proper medicines can be prescribed.

I have sleep disorder from last 8 years. During the sleep dreams comes. I took quatan 25mg and nexito forte approx 5 years.After changing the doctor i have been prescribed mirtaz 7.5mg ,nexito 10 and 0.5 lonazep fir 2 years. After that i took sertraline 50mg ,lonazep 0.5mg then 100 mg sertraline ,lonazep 0.5mg then mirnite 15mg then 100 mg sertraline ,lonazep 0.5mg and arip mt-5 . I am getting a solutions for sleep disorder. You are requested to review and advise me.

Dr. Jyoti Kapoor Madan

Psychiatrist

Sleep problems are often caused by underlying physical and/ or psychological cause. This requires examination of the patient so that proper treatment can be initiated. Often stress/ anxiety/ depression or mood disorder needs to be dealt with and sleeping pills are not adequate treatment. Please go through the link below - http://drjyotikapoor.com/2015/01/26/sleep-disorders/

Do you have any questions related to Dothivin 50 mg Tablet?

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User Feedback

What are you using Dothivin Tablet for?

Anxiety disor*

100%

*Anxiety disorder

FAQs

Q. Is Dothivin a sedative?

No. Dothivin is an antidepressant (TCA) that is used to treat depression, nerve pain, and anxiety disorder. It can cause drowsiness or sedation as a side effect. Therefore caution is advised when driving or operating dangerous machinery and even when getting out of bed at night.

Q. Is Dothivin a muscle relaxant?

No. Dothivin is not a muscle relaxant. It is a tricyclic antidepressant (TCA) used in the treatment of depression, nerve pain, and anxiety disorder.

Q. What is the difference between Dothivin and amitriptyline?

Dothivin is chemically related to Amitriptyline and both are tricyclic antidepressant (TCA) medicine. There is overlap in pharmacological property of this medicine.

Q. Is Dothivin the same as doxepin?

Dothivin and doxepin are different medicines but belong to the similar chemical class. Doxepin, at low doses, can improve sleep in patients with insomnia. It is also available in the topical form for use in various neuro-dermatitis syndrome, especially itching.

Q. How to stop Dothivin?

If your doctor asks you to stop Dothivin, you should reduce the dose slowly over 4 weeks. You should not discontinue it abruptly. Sudden discontinuation may cause aggression, anxiety, blurred vision, concentration impairment, constipation and crying spell.

Q. Is Dothivin fatal?

Yes. Dothivin can be fatal (can cause death) in overdose. This is due to a life-threatening or dangerous side effect in overdose like hyperthermia, seizure, arrhythmia, tachycardia, orthostatic hypotension or sudden death. That's why it is generally not considered a first-line option for depression because of side effect profile.

Q. Can Dothivin be used along with mirtazapine?

It is better to avoid Dothivin with mirtazapine. Mirtazapine, which is used in the treatment of depression, can potentiate the sedative effects of Dothivin.

Q. Can Dothivin be used with citalopram?

No. Citalopram and Dothivin both are the antidepressant. Citalopram may increase the high blood level of Dothivin. This may lead to a life-threatening or dangerous side effect of hyperthermia, seizure, arrhythmia, tachycardia, orthostatic hypotension or sudden death.

Q. Can Dothivin be used with sertraline?

No. Sertraline and Dothivin both are the anti-depressant. Sertraline may increase the high blood level of Dothivin. This may lead to a life-threatening or dangerous side effect of hyperthermia, seizure, arrhythmia, tachycardia, orthostatic hypotension or sudden death.

Q. Can I take Dothivin with diazepam?

It is better to avoid this combination. Diazepam is a sedative drug and Dothivin may cause sedation as a side effect too. Taking both of them together can increase the drowsiness or sleepiness. Inform your doctor if you are taking diazepam.

Q. Can Dothivin be used in the treatment of trigeminal neuralgia?

No. Dothivin is not approved for the treatment of trigeminal neuralgia. Trigeminal neuralgia is a chronic pain condition that affects the trigeminal or 5th cranial nerve, one of the most widely distributed nerves in the head.

Q. Can Dothivin be used in the treatment of burning mouth syndrome?

No. Dothivin is not approved for the treatment of burning mouth syndrome. Burning mouth syndrome is a painful condition of mouth that is burning, scalding, tingling or feeling of numbness that may occur every day for months or longer.

Q. Can I take Dothivin for depression?

Yes. Dothivin is indicated for the treatment of depression. It has a potential advantage in the patient with depression if associated with insomnia and anxiety. It is generally not considered a first-line option for depression because of side effect profile but very useful for severe or treatment-resistant depression.

Q. Can Dothivin used to treat IBS (Irritable Bowel Syndrome)?

No. Dothivin is not approved for the treatment of Irritable Bowel Syndrome (IBS). Irritable Bowel Syndrome is a functional gastrointestinal disorder characterised by chronic or recurrent abdominal pain or discomfort associated with altered bowel habits.

Q. Can Dothivin be used to treat insomnia with depression?

Yes. Dothivin may be used for the treatment of insomnia (too much arousal both at night and during the day) associated with depression. Because it can cause drowsiness or sedation as side effects, it is effective in treating insomnia associated with depression.

Q. Can I use Dothivin for fibromyalgia?

Yes. Dothivin is not approved for the treatment of fibromyalgia. Fibromyalgia is a pain syndrome with tenderness but no structural pathology in muscles, ligamanets or joints.

Q. Can I use Dothivin for nerve pain?

Yes. Dothivin is indicated for the treatment of nerve pain/neuropathic pain. Chronic pain/Neuropathic pain is described as pain that arises from damage to, or dysfunction of, any part of peripheral or central nervous system. It is associated with the disease which can affect nerves like diabetes mellitus or herpes infections.

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Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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References

Stahl SM, editor. Dothiepin. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 205-10.
Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 20 Mar. 2019] (online) Available from:
PubChem. Dothiepin. [Accessed 22 Mar. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 22 Mar. 2019] (online) Available from:

Manufacturer/Marketer Address

Industrial Estate,madhupatna Industrial Estate,madhupatna, Madhupatna, Cuttack-753010, Odisha, India

A licensed pharmacy from your nearest location will deliver Dothivin 50mg Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your prescription and the availability of this medicine.